Clinical trials: Inhalation; Gas
Oxygen Inhalation Therapy, Labour
Maternal Oxygen Administration for Fetal Distress II
Supplementary oxygen is routinely administered to patients, even those with adequate oxygen saturations, in the belief that it increases oxygen delivery.
- Conditions
- Oxygen Inhalation Therapy, Labour, Fetal Distress
- Trial name
- NCT03764696
- Testing
- tight-fitting simple facemask
- Where
- 3 sites in China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Navy General Hospital, Beijing
Healthy Volunteers
Development of Hardware and Software for Pulmonary Magnetic Resonance Imaging Using Inhaled Tracer Gases
This is a single centre study. The overarching hypothesis of this study is that MRI with inhaled tracer gases can provide high quality images of lung function to complement conventional 1H MRI.
- Trial name
- NCT04726618
- Testing
- Hyperpolarized 129-xenon gas and Perfluoropropane gas
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Prostatic Neoplasm, Urinary Bladder Neoplasm
The Effect of Prolonged Inspiratory Time on Gas Exchange During Robot-assisted Laparoscopic Surgery With Steep Trendelenburg Position : A Crossover Randomized Clinical Trial
Gas exchange disturbance frequently occurs in steep Trendelenburg position during robot-assisted laparoscopic prostatectomy or cystectomy.
- Trial name
- NCT02966535
- Testing
- Adjustment of Mechanical Ventilator Inspiratory to expiratory time ratio (1:2 to 1:1), Adjustment of Mechanical Ventilator Inspiratory to expiratory time ratio (1:1 to 1:2)
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Aging
The Effect of Age and Inspiratory Resistance on the Inspiratory Gas Levels While Wearing Air Purifying Respirator "
20 healthy young subjects and 20 healthy older subjects will go through a medical examination. Subjects will be asked for their medical history especially on respiratory and cardiac diseases.
- Trial name
- NCT03522493
- Testing
- "Yaalom Katom"
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Healthy
Safety of Inhaled Hydrogen Gas Mixtures in Healthy Volunteers
Hydrogen gas may decrease the degree or incidence of brain injury following ischemia. The purpose of this study is to determine the safety and tolerability of inhaled hydrogen gas at the dose exposures required for a clinical…
- Trial name
- NCT04046211
- Testing
- Hydrogen
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Accident Caused by Snow Avalanche
Physiological Values When Breathing in an Air-pocket. Mountain Lab 2019 (ML2019)
The literature describes and report neurologic intact patients surviving an avalanche several hours after they were buried. The most important factor for surviving more than 15-35 min of burial is considered to be the presence of…
- Trial name
- NCT03911011
- Testing
- Fresh air
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Inhalation; Gas
Sevoflurane Wash in Method Using Conventional Flows Versus Low Flows of 0.5L
The goal of this observational study is to to evaluate a technique of initiating Sevoflurane low-flow anesthesia which is simple, has a quick wash-in and minimises gas consumption without compromising the safety when compared to…
- Trial name
- NCT06209112
- Testing
- Sevoflurane
- Where
- Oman
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Royal Hospital, Oman
Nitrous Oxide Poisoning
Effects of Low Concentrations of Nitrous Oxide
The aim of the study is to test the effects of low concentrations of nitrous oxide on cognitive functions and reaction time in human.
- Trial name
- NCT04050267
- Testing
- Nitrous Oxide
- Where
- Czechia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
COPD
Evaluation Inhaled Corticosteroids on Exhaled Nitric Oxide Gas Exchange
To evaluate the role of inhaled corticosteroids to suppress nitric oxide gas exchange in stable patients with moderate-to-severe COPD who are current non-smokers and not on oral corticosteroids.
- Trial name
- NCT00568347
- Testing
- fluticasone 100mcg/ salmeterol 50mcg, fluticasone 250/salmeterol 50, salmeterol
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Arthur F Gelb MD
Healthy Volunteers - Male and Female
¹²⁹Xe(XENON) MRI Program
Healthy volunteers aged 18 to 85 will undergo hyperpolarized Xenon-129 (¹²⁹Xe) MRI and pulmonary function testing. The study aims to develop evaluation tools for ventilation defect percent (VDP), signal-to-noise and…
- Trial name
- NCT07533981
- Testing
- Hyperpolarized Xenon MRI
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Alexei Ouriadov
Accident Caused by Snow Avalanche
Snow Properties and Its Modeling for Studying Gas Exchange Under the Simulated Avalanche Snow
The aim of the study is to investigate respiratory parameters of a person in the simulated avalanche snow and consequent use of the measured data for development of a mathematical-physical model of breathing during increasing…
- Trial name
- SPAM (NCT03413878)
- Testing
- Breathing in the simulated avalanche snow
- Where
- 2 sites in Czechia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Work of Breathing
The Gas Mask: the Effects on Respiration!
Background: The gas mask is used to protect military and non-military subjects exposed to respiratory hazards (CBRN agents). The aim of the study was to evaluate the impact of the gas mask on respiratory patterns and indexes of…
- Trial name
- NCT02782936
- Testing
- measurement of the work of breathing, Gas mask
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Laval University
Hypoxia, Normobaric Hypoxia
Effect of Acute Hypoxia on RIght VEntRicular Function in Healthy Adults.
More and more people are engaging in sports in the mountains, including individuals with heart or lung diseases. At the same time, such diseases are becoming more common in Switzerland.
- Conditions
- Hypoxia, Normobaric Hypoxia, Altitude Hypoxia, Right Heart Function
- Trial name
- RIVER-H (NCT07431567)
- Testing
- Normobaric Hypoxia
- Where
- 2 sites in Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mona Lichtblau
Healthy Volunteer Study
Exploratory Clinical Study to Assess Safety and Efficacy of Xenon Gas Inhalation to Control Neuroinflammation
The goal of this clinical study is to evaluate safety of Xenon gas inhalation in healthy volunteers. This first phase safety clinical study is part of evaluation of the xenon gas inhalation as a therapy for neurodegenerative…
- Trial name
- NCT06945614
- Testing
- Xenon gas inhalation
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- General Biophysics LLC
Idiopathic Pulmonary Fibrosis
Inhaled Nitric Oxide (iNO) in Idiopathic Pulmonary Fibrosis (IPF).
Idiopathic Pulmonary Fibrosis (IPF) is a progressive lung disease marked by reduced exercise capacity and activity-related breathlessness (commonly termed dyspnea).
- Trial name
- NCT05052229
- Testing
- Nitric Oxide, Medical air
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. Denis O'Donnell
Acute Mountain Sickness
Voluntary Isocapnic Hyperpnea in Hypoxia to Mitigate Acute Mountain Sickness
This study investigates the effects of a brief Voluntary Isocapnic Hyperpnoea (VIH) on Acute Mountain Sickness (AMS) symptoms, SpO₂, blood pressure, and blood gas homeostasis in normobaric hypoxia, to evaluate whether such…
- Trial name
- NCT07126834
- Testing
- VIH
- Where
- Poland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institute of Sport - National Research Institute, Poland
Healthy Volunteers - Male and Female
¹⁹F (Perfluoropropane) MRI
Healthy volunteers aged 18 to 85 will undergo ¹⁹F (perfluoropropane) MRI to support the development of imaging sequences, reconstruction algorithms, and hardware necessary for acquiring high-spatial resolution lung images.
- Trial name
- NCT07305532
- Testing
- 19F(perfluoropropane) MRI
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Alexei Ouriadov
High Altitude, Inhalation; Gas
Effect of Inhalation of Low Dose CO2 on Exercise Performance at High Altitude
High altitude (>2400 m) is associated with decreased atmosphere pressure leading to hypoxia which in turn impairs exercise capacity and causes acute mountain sickness (AMS).
- Conditions
- High Altitude, Inhalation; Gas, Acute Mountain Sickness
- Trial name
- NCT05798416
- Testing
- Exercise under inhalation CO2, Exercise under inhalation ambient air
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- State Key Laboratory of Respiratory Disease
Acute Mountain Sickness, High Altitude
CO2 Supplement for Treatment of Acute Mountain Sickness
It was reported that up to 76% people who rapidly ascend to the altitude higher than 4500 m without sufficient acclimatization will have AMS which often develops 6-8 hours after reaching at high altitude.
- Conditions
- Acute Mountain Sickness, High Altitude, Inhalation; Gas
- Trial name
- NCT06393998
- Testing
- Breathing with CO2 during daytime and night at high altitude, Sleep and doing exercise test under inhalation of air
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- State Key Laboratory of Respiratory Disease
Respiration, Artificial, Critical Illness
Medical Gas Humidification During Noninvasive Mechanical Ventilation
In this study, the investigators aimed to study the role of medical gas humidification during noninvasive mechanical ventilation.
- Trial name
- NCT00124345
- Testing
- MR730
- Where
- Italy
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital