Clinical trials: Inhalation
Inhalation of Nitrous Oxide, Opioid Analgesic Adverse Reaction
Combination of Nitrous Oxide 70% With Fentanyl Intranasal for Procedural Analgosedation in Children
This study analyzes the analgesic efficacy and adverse events of nitrous oxide 70% combined with basic analgetics compared to nitrous oxide 70% with fentanyl intranasal for analgosedation for short and painful procedures in…
- Conditions
- Inhalation of Nitrous Oxide, Opioid Analgesic Adverse Reaction, Pain
- Trial name
- NCT02533908
- Testing
- Fentanyl intranasal, NaCl 0.9% intranasal
- Where
- Switzerland
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Postoperative Pain
The Role of Preoperative Melatonin in Reducing the Inhaled Isoflurane Requirements in Open Nephrectomy
Melatonin is a hormone that the pineal gland in the brain produces. Melatonin fulfills many functions in the body but it is mostly known for maintaining a circadian rhythm that is governed by the central circadian pacemaker…
- Trial name
- NCT04959825
- Testing
- Melatonin 5 mg, Sugar Coated Tablets
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Birch Pollen Allergy, Healthy Control Subjects
Effect of the Nasal Provocation on the Breathing Style
The purpose of this study is to find out how the provocation of the nose changes breathing style (specifically, frequency and tidal volume changes)
- Trial name
- NCT02146300
- Testing
- 1. session birch pollen nasal exposure 2. session xylometazoline nasal exposure
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Innate Immunity
Effect of Anti-Inflammatory Agents on Biological Responses to Endotoxin Inhalation in Healthy Subjects
The main objective of this study is to characterize the biological responses elicited by endotoxin inhalation applied to healthy subjects, and to assess the effect of standard anti-inflammatory agents (i.e.
- Trial name
- NCT02252809
- Testing
- adalimumab, methylprednisolone
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Hyperoxia
Hyperoxygenation in Anesthetized Children
This study is aiming at assessing the effect of inspired oxygen fraction during general anesthesia on children's lung mechanics and volume.
- Trial name
- OXPED (NCT02384616)
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Walid HABRE
Breathing, Mind-body Practices
Study to Measure Relaxation From Different Types of Focused Breathing Exercises
Mind-body practices, such as yoga, ta'i chi, mindfulness and biofeedback, commonly use slow breathing techniques to induce physiological and mental relaxation.
- Conditions
- Breathing, Mind-body Practices, Yoga, Meditation
- Trial name
- NCT02226744
- Testing
- Focused Breathing
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Sleep Disordered Breathing
Evaluation of Software Enhancements to the Respironics BiPAP autoSV Device Compared to BiPAP S/T Device
This study is being undertaken to collect data from Respironics, Inc's BiPAP autoSV3 and compare with data from Respironics, Inc's BiPAP S/T device, to confirm that the algorithms in the BiPAP autoSV3 device can safely and…
- Trial name
- SV3-ST (NCT01241604)
- Testing
- BiPAP S/T, BiPAP Auto SV3
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Philips Respironics
Progressive Muscle Relaxation, Deep Breath
Progressive Muscle Relaxation and Deep Breathing Exercises
The population of the study was composed of 186 patients whose cells were assigned to Atatürk University Hospital Educational Diseases Polyclinic between April and June 2023, and whose cells were found to have COPD according to…
- Conditions
- Progressive Muscle Relaxation, Deep Breath, COPD
- Trial name
- NCT05846204
- Testing
- Progressive Muscle Relaxation, Deep Breathing Exercise Group-DBE
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Asthma, Distal Lung Inflammation
Mentored Patient-Oriented Research Career Development Award
Asthmatics have inflammation in the large airways (tubes through which air travels in and out of the lungs). The large airways are located in the central lung.
- Trial name
- NCT00203684
- Testing
- Flunisolide-HFA, Flunisolide-CFC
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Safety Issues
Phase 1A Safety Trial of Inhaled PK10571 (GB002)
This is a phase 1A randomized double blind placebo controlled single ascending dose and multiple ascending dose trial of inhaled PK10571 (GB002) in healthy adult subjects.
- Trial name
- NCT03473236
- Testing
- GB002, Generic Dry Powder Inhaler
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- GB002, Inc., a wholly owned subsidiary of Gossamer Bio, Inc.
Haemorrhage
A Non-investigational Product (IP) Study to Investigate Lung Function in Women in the Third Stage of Labour
The purpose of this study is to record and compare the inhalation profiles of non pregnant women and those who are in the third stage of labour.
- Trial name
- NCT02106000
- Testing
- Inhalation profile recorder
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
E Cigarette Use
A Behavioral Circuit Breathing Training Intervention on Smoking Cessation and Respiratory Function Among Youth Who Use E-cigarettes
This study aims to evaluate the effects of a six-week behavioral circuit breathing training intervention on smoking cessation and respiratory function compared with diaphragmatic breathing training and usual daily activities
- Trial name
- NCT07882407
- Testing
- Circuit Breathing Intervention, Diaphragmatic Breathing
- Where
- Thailand
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Acute Allergic Reaction, Anaphylaxis
Phase 1 Crossover Study Evaluating the Safety, Tolerability, and Pharmacokinetics of KP001 in Healthy Adult Volunteers
The goal of this clinical trial is to evaluate the safety, tolerability, and pharmacokinetics (PK) of several KP001 dose regimens to identify a treatment regimen with a PK profile that safely meets or exceeds the PK profile of…
- Trial name
- NCT06963411
- Testing
- KP001
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kokua Pharma Inc.
Healthy
Single Ascending Dose and Multiple Ascending Dose Study of Niclosamide Inhalation Powder in Healthy Adult Subjects
This is a Phase 1 (healthy adult volunteers), 2-part, double-blind, randomized, placebo controlled trial to evaluate the safety and pharmacokinetic (PK) profiles of escalating single doses of Niclosamide Inhalation Powder versus…
- Trial name
- NCT05168644
- Testing
- Niclosamide Inhalation Powder
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TFF Pharmaceuticals, Inc.
Accident Caused by Snow Avalanche
Evaluation of Gas Propagation in Snow During Breathing of Subjects Under Simulated Avalanche Snow
The study is aimed at investigation of respiratory gases propagation in snow. The study involves volunteers breathing into the snow whereas concentrations of gases are measured at various positions in the snow.
- Trial name
- GasProp (NCT05262894)
- Testing
- extreme hypercapnia induced by ventilation insufficiency
- Where
- Czechia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Mild Cognitive Impairment
Effects of Thai Dance With Twenty-five Squares in Elderly With Mild Cognitive Impairment
The objective of this study was to determine the effects of Thai dance with twenty-five squares on cerebrovascular and cognitive function in elderly with mild cognitive impairment
- Trial name
- NCT06236646
- Testing
- Thai dance with twenty-five squares (TDT), Control (CON)
- Where
- 2 sites in Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Older Adults (60 - 85 Years Old)
Effect of Exercise of Shoulder - Pelvic Coupling Pattern on Breathing Using Proprioceptive Technique
The purpose of this study is to determine the effects of proprioceptive neuromuscular facilitation scapula-pelvis coupling pattern exercise on Respiratory capacity and quality of life in elderly people aged 65 years or older and…
- Trial name
- NCT07442942
- Testing
- PNF combination of scapular and pelvic pattern intervention, Chest cages expansion exercises intervention
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boung-hyoun Moon
Lower Respiratory Tract Disease, Respiratory Disease
The Effects Of Toy In Chıldren Durıng Inhaler Therapy
The purpose of the study is to investigate the effect of using a toy that children like during inhaler treatment on children's anxiety and emotional state.
- Trial name
- NCT06924528
- Testing
- using toy during inhaler treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Pneumonia
Combined Effects of Breathing Teach Back Training And Percussion In Patients With Pneumonia
Pneumonia, marked by lung inflammation, leads to symptoms like fever and difficulty breathing, affecting millions globally. It particularly impacts children and the elderly.
- Trial name
- NCT06732739
- Testing
- percussions with teach-back breathing exercise, PERCUSSION
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Psychological Well Being, Behavioral Management
Behavioral Management and Psychological Well-Being
The aim of present study is to evaluate whether a program of behavioral and cognitive procedures for emotional control, and assertive training, produces well-being and improvement in quality of life of healthy volunteers.
- Trial name
- NCT01823601
- Testing
- Behavioral Management Program, Seminars in Health
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Centro de Estudos em Medicina Comportamental
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