Clinical trials: Inhalation
Pain
The Role of Opioidergic Systems in Breathing Based Analgesia
The purpose of this psychophysical and pharmacologic study is to determine if slow-breathing induced pain relief is mediated by endogenous opioids in response to intravenous (IV) administration of the opioid antagonist naloxone…
- Trial name
- NCT03419858
- Testing
- Mindfulness Meditation, Slow-Breathing, Naloxone
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Asthma
Comparison of Absorption of Budesonide and Formoterol From Budesonide/Formoterol Easyhaler and Symbicort Turbuhaler
The purpose of this study is to compare the test product Budesonide/formoterol Easyhaler with the marketed product Symbicort Turbuhaler in terms of the drug absorbed into the bloodstream.
- Trial name
- NCT01593826
- Testing
- Charcoal and Budesonide/formoterol Easyhaler 320/9 microg, Charcoal and Symbicort Turbuhaler, Budesonide/formoterol Easyhaler 320/9 microg
- Where
- Finland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Orion Corporation, Orion Pharma
E Cigarette Use
Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users
This study aims to investigate the acute effects of a circuit breathing intervention on nicotine withdrawal symptoms and respiratory parameters among youth who use e-cigarettes.
- Trial name
- NCT07886099
- Testing
- Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Vagus Nerve Stimulations
Comparison of the Acute Effects of Auricular Vagus Nerve Stimulation and Deep Breathing Exercise
The goal of this clinical trial is to investigate whether vagus stimulation and breathing exercises are more effective in healthy adults.
- Trial name
- NCT06740032
- Testing
- Transcutaneous vagus nerve stimulation, Deep breath exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Panic Disorder
Breathing Regulation Training for Individuals With Panic Disorder
This study will compare two different breathing regulation techniques to determine which is more effective in reducing the rate of panic attacks in people with panic disorder.
- Trial name
- NCT00183521
- Testing
- Raise-CO2 breathing regulation training, Lower-CO2 breathing regulation training, Control
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Stanford University
Sleep Breathing Disorders
A Clinical Trial Evaluating the Effectiveness and Safety of a mmWave Radar Based Sleep Respiratory Monitoring System
This study compares the diagnostic capability of a millimeter-wave radar-based Sleep Respiratory Monitoring System to the gold standard polysomnography.
- Trial name
- NCT06038006
- Testing
- Sleep Respiratory Monitoring System
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Changsha Tsingray Technology Co., Ltd.
Snoring, Mouth Breathing
Does myTAP Oral Appliance Therapy Including a Mouth Shield Lessen Periodontitis in Mouth-Breathers Who Snore?
Mouth breathing, snoring and poor sleep can contribute to and worsen periodontitis (gum disease). The purpose of this study is to test whether the myTAP oral appliance with a mouth shield (OA+) can lessen periodontal symptoms in…
- Conditions
- Snoring, Mouth Breathing, Daytime Sleepiness, Periodontitis
- Trial name
- OAplusPerio (NCT06797089)
- Testing
- Oral appliance therapy plus scaling and root planing on left or right of mouth
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Fatigue
Fatigue and Kinematics During Isometric Activity of the Upper Limbs in Young and Older Adults
The aim of this study is to understand the relationship between perceived effort and physiological and kinematic variables caused by isometric activity of the upper limbs, as well as its relationship with socio-demographic…
- Trial name
- NCT04938791
- Testing
- Isometric activity
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Saude da Cruz Vermelha Portuguesa - Lisboa
Miscellaneous Disorders in the Fetus or Newborn
The Safety and Adverse Reaction Study of Neonatal to Inhaled Carbon Monoxide
Based on the study about carbon monoxide in human inflammatory and other beneficial physiological function , now we'll be going to research its application in neonates .Phase 1 Study as a foundation for the further test is, the…
- Trial name
- CO (NCT01818843)
- Testing
- Inhaled Carbon Monoxide
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- CAN WANG
Healthy Participants
ACUTE EFFECTS OF INSPIRATORY MUSCLE WARM-UP ON INSPIRATORY MUSCLE STRENGTH DURING AEROBIC AND ANAEROBIC EXERCISE IN ATHLETES
Inspiratory muscle warm-up (IMW) is a specific pre-exercise breathing intervention designed to prepare the respiratory muscles before physical activity and potentially enhance exercise performance.
- Trial name
- IMW-AE (NCT07445269)
- Testing
- Inspiratory Muscle Warm-Up (40% MIP)
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hitit University
Intensive Care Unit Syndrome, Muscle Weakness
Inspiratory Muscle Training and Expiratory Muscle Thickness
the specific effect of IMT on expiratory muscle strength and abdominal wall thickness during weaning remains unclear. To address this significant research gap, the primary objective of our study was to evaluate the effect of IMT…
- Conditions
- Intensive Care Unit Syndrome, Muscle Weakness, Rehabilitation
- Trial name
- NCT06251791
- Testing
- conventional physiotherapy+ IMT, conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Demiroglu Bilim University
Acute Inflammatory Response to Non-antigenic Stimulus
Phase 1a Study in Healthy Smokers to Investigate the Effect With MMI-0100 on Airway Inflammation in Induced Sputum After Challenge With Inhaled Lipopolysaccharide
A Phase 1a, randomized, placebo controlled, two-way crossover study is to determine the effect of inhaled MMI-0100 compared to placebo following LPS challenge on inflammatory markers.
- Trial name
- LPS (NCT02515396)
- Testing
- MMI-0100
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Moerae Matrix, Inc.
Influenza
Safety, Tolerability, and PK of Escalating Doses of Flufirvitide-3 Dry Powder for Inhalation in Healthy Subjects
To evaluate the safety, tolerability and pharmacokinetics (PK) of single,and repeat escalating doses of FF-3 dry powder administered via inhalation in healthy adult subjects
- Trial name
- NCT01990846
- Testing
- Flufirvitide 3
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Autoimmune Technologies, LLC
Healthy
Study to Investigate Safety and Tolerability of BI 1744 CL in Free Dose Combination With Tiotropium Bromide Both Administered by Respimat® in Healthy Male Volunteers
Study to investigate safety and tolerability of single, inhaled doses (2.5 μg, 5 μg, 10 μg, 20 μg and 40 μg) of BI 1744 CL in free dose combination with tiotropium bromide 5 μg (for doses up to and including 20 μg BI 1744 CL) and…
- Trial name
- NCT02259946
- Testing
- BI 1744 CL, Tiotropium bromide
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Fear Anxiety
Inhalation Treatment Distraction in Children
The aim of the project is to examine the effects of two different distraction methods used in preschool children receiving inhalation therapy on fear and anxiety levels.
- Trial name
- NCT06874491
- Testing
- Moving and 3D Book, Hand Puppet
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Autonomic Nervous System Disease
Resonance Breathing and Postural Resonance: Acute Modulation of Autonomic and Hemodynamic Responses Via Arterial Baroreflex Mechanisms
This randomized crossover study compared the acute autonomic and hemodynamic responses to three experimental conditions: control, resonance breathing (RB), and postural resonance (PR), in healthy young adults.
- Trial name
- Autonomic (NCT07536997)
- Testing
- Resonance Breathing, Postural Resonance
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Aging
The Effect of Age and Inspiratory Resistance on the Inspiratory Gas Levels While Wearing Air Purifying Respirator "
20 healthy young subjects and 20 healthy older subjects will go through a medical examination. Subjects will be asked for their medical history especially on respiratory and cardiac diseases.
- Trial name
- NCT03522493
- Testing
- "Yaalom Katom"
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Acute Respiratory Distress Syndrome
Decision Support System to Evaluate VENTilation in ARDS
Patients with Acute Respiratory Distress Syndrome (ARDS) residing in the intensive care unit (ICU) often require support for their breathing from a mechanical ventilator to provide adequate gas exchange, and although it is…
- Trial name
- DeVENT (NCT04115709)
- Testing
- Beacon Caresystem device with advice, Beacon Caresystem device without advice activated
- Where
- 3 sites in Austria, France and 1 more
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Breathing, Mind-body Practices
Study to Measure Relaxation From Different Types of Focused Breathing Exercises
Mind-body practices, such as yoga, ta'i chi, mindfulness and biofeedback, commonly use slow breathing techniques to induce physiological and mental relaxation.
- Conditions
- Breathing, Mind-body Practices, Yoga, Meditation
- Trial name
- NCT02226744
- Testing
- Focused Breathing
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Bronchopulmonary Dysplasia
Early Predictors of Bronchopulmonary Dysplasia in Extremely Preterm Infants
Bronchopulmonary dysplasia (BPD) remains one of the most common complications in extremely preterm infants despite advances in neonatal intensive care.
- Trial name
- EPIRESP (NCT07771387)
- Where
- Austria
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
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