Clinical trials: Injections
Healthy Japanese and Caucasian Male Adults
Phase 1 Single Subcutaneous Dose Study of MLN1202
The objective of the study is to investigate the safety, pharmacokinetics, and pharmacodynamic effect of a single dose of MLN1202 in healthy Japanese male adults.
- Trial name
- NCT02426021
- Testing
- MLN1202
- Where
- Japan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Takeda
Procedural Pain
The Effect of Audio Book and Local Vibration on Pain and Fear in Intramuscular Injection in Children
The study is conducted based on a randomized controlled experimental design to determine the effect of an audio book and local vibration on intramuscular injection in pediatric emergency unit patients aged 4-6 years on pain and…
- Trial name
- NCT06354608
- Testing
- Audio Book Group, Local Vibration Group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Bruxism
Change in Biting Force After Botox Injection
Implant rehabilitation is a successful treatment option for edentulous patients. Decreasing bone loss around implants is an important target for all implantologists.
- Trial name
- NCT04940104
- Testing
- Botox Injectable Product
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Children, Respiration Disorder
The Effect of a Multimodal Approach on Pain, Fear, and Anxiety in Injection Experiences in Children
Reducing the pain and fear experienced by children during IM injections, one of the painful procedures commonly seen in emergency departments, is an important midwifery/nursing intervention.
- Trial name
- Randomized (NCT07509164)
- Testing
- Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Pain and Anxiety During Intramuscular Injection
Effects of Virtual Reality Glasses and Stress Ball Application on Pain, Anxiety and Patient Satisfaction in Intramuscular Injection Application
Purpose: This study was planned to examine the effects of virtual reality glasses and stress ball application on pain, anxiety and patient satisfaction in intramuscular injection application.
- Trial name
- NCT06512909
- Testing
- Virtual Reality Glasses Application, Stress Ball Application
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
HIV Pre-exposure Prophylaxis
Study of Lenacapavir as a Once-Yearly Injection for HIV Pre-exposure Prophylaxis (PrEP)
The goal of this clinical study is to learn more about the study drug lenacapavir (LEN), safety, tolerability, and pharmacokinetics (how LEN is absorbed, modified, distributed, and removed from the body of the participants) of…
- Trial name
- PURPOSE 365 (NCT07047716)
- Testing
- Lenacapavir Injection, Lenacapavir Tablet
- Where
- 31 sites in United States
- Volunteers
- 339 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Motor Learning, Physical Activities
Video Modeling on Shot-Put Acquisition
Video modeling is widely used in motor skill instruction, yet its optimal modality and timing within a session remain unclear, particularly for complex athletic tasks.
- Conditions
- Motor Learning, Physical Activities, Video Modeling
- Trial name
- NCT07849504
- Testing
- Video expert Modeling, Video self-modeling, Peer-to-peer learning video
- Where
- Tunisia
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- High Institute of Sports and Physical Education of Kef
Healthy Volunteers
Biopsy Study for Sculptra (Poly-L-Lactic Acid)
The primary objective of this study involves research to evaluate new collagen (the elastic fibers that provide skin with its strength and resilience) formation in the skin following injections of Sculptra (Poly-L-Lactic Acid or…
- Trial name
- NCT00869687
- Testing
- Poly-L-Lactic Acid Injection
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Gummy Smile Due to Hypermobile Upper Lip
Satisfaction Of Adult Patients With Gummy Smile Treated By Botulinum Toxin A Injection
The aim of the proposal study is to answer the question of how to manage gummy smiles due to hypermobile upper lip with less invasive and low risk level procedure .
- Trial name
- NCT03186547
- Testing
- Botulinum Toxin A Injection, Modified Lip Repositioning Surgery
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
COVID-19
Clinical Study of F61 Injection in Healthy Chinese Subjects
Main purpose： To evaluate the safety and tolerability of single-dose ascending intravenous infusion of F61 in healthy subjects. Secondary purpose： To evaluate the pharmacokinetic profile and immunogenicity of F61 administered by…
- Trial name
- NCT05483504
- Testing
- F61 injection
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wuhan Institute of Biological Products Co., Ltd
Aesthetics, Intradermal Injections
Clinical Evaluation of the Safety and Performance of a Filler in Correction of Mid-face Age-related Volume Deficit
Prospective, single center study, on healthy subjects to evaluate the aesthetic improvement of facial volume, effect on the restoration and/or augmentation in subjects with mid-face age-related volume deficit after injection of a…
- Trial name
- NCT04505319
- Testing
- DEFINISSE CORE FILLER
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Relife S.r.l.
Dental Anxiety, Dental Fear
The Effect of a Kaleidoscope and Cartoons for Dental Treatment in Children
Dental fear and anxiety are among the most common challenges encountered in pediatric dental practice and may negatively affect children's cooperation and acceptance of dental treatment.
- Conditions
- Dental Anxiety, Dental Fear, Pain
- Trial name
- Pain (NCT07462364)
- Testing
- Kaleidoscope Distraction, Cartoon Distraction
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Dicle University
Episiotomy Wound
Comparison Between Lidocaine Prilocaine Cream and Lidocaine Injection on Pain Control During Episiotomy.
The present study aims to compare the effects of lidocaine-prilocaine cream and lidocaine injection on the reduction of pain while doing and repairing episiotomy, controlling the pain in the post-partum period, and reduction the…
- Trial name
- NCT05891132
- Testing
- 10 ml of lidocaine 2%, lidocaine prilocaine cream 15gm
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy
Study to Compare Blood Levels of Ceftriaxone Given by Suppository or Injection.
Phase 1, three-way cross-over, randomised, open label comparison of intravenous versus two rectal dosage forms of ceftriaxone in 37 healthy Thai adults.
- Trial name
- CefREC (NCT03895567)
- Testing
- A. Ceftriaxone (Roche ®) 500mg (slow intravenous injection), B. Ceftriaxone rectal dosage form test formulation 1 (1 x 500mg), C. Ceftriaxone rectal dosage form test formulation 2 (1 x 500mg)
- Where
- Thailand
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Intramuscular Injection Pain
Effect of Traction-Pressure-Release and Manual Pressure on Intramuscular Injection Pain
The goal of this clinical trial is to evaluate whether two different intramuscular (IM) injection techniques-Manual Pressure and Traction-Pressure-Release (TPR)-can effectively reduce injection-related pain and improve patient…
- Trial name
- IM-PainTech (NCT07262463)
- Testing
- Standard Intramuscular Injection, Manual Pressure Technique, Traction-Pressure-Release (TPR) Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Melek Sahin
Healthy Volunteers
Bioequivalence Study With Pharmacokinetic Endpoints, Comparing a Single Dose of Iron Sucrose Azad Injection of Azad Pharma Corporation (AG), With a Single Dose of Venofer® Injection of Vifor Corporation (AG) in Healthy Adult Volunteers
A Clinical Trial to Demonstrate the Comparability of the Two Iron Sucrose Injection Solutions Iron Sucrose Azad of Azad Pharma AG and Venofer® of Vifor Pharma AG.
- Trial name
- NCT02391181
- Testing
- Iron Sucrose Azad, Venofer®
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Azad Pharma AG
UC - Ulcerative Colitis
To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of LYNC-101 for Injection in Healthy Adult Participants
This Phase I study is designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity, and cytokine profiles of LYNC-101 for Injection in healthy adult participants.
- Trial name
- NCT07505030
- Testing
- LYNC-101
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- LyncBio Therapeutics Co., Ltd.
Pain
Minimal Effective Concentration of Lidocaine in Propofol Lidocaine Mixture for Relief of Pain on Propofol Injection
The research will be carried out in order to determine the optimal lidocaine concentration in propofol lidocaine mixture to prevent pain on propofol injection during induction of general anesthesia using a modified Dixon's…
- Trial name
- NCT05165303
- Testing
- lidocaine with propofol
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Pruritus
Study of Itch Control by VLY-686 in Healthy Volunteers After Intradermal Injections of Substance P
The purpose of this study is to test whether VLY-686 can prevent or reduce the itch and dermatological reaction observed after healthy volunteers are injected with Substance P in comparison with placebo.
- Trial name
- NCT01919944
- Testing
- VLY-686
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Vanda Pharmaceuticals
General Anesthesia
Dose-Finding and Human Abuse Potential Study Of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users
Part 1: To determine the doses of IV HSK3486 and propofol for use in Part 2, the abuse potential part of the study. Part 2: To evaluate the abuse potential of HSK3486 compared with propofol when administered IV to healthy…
- Trial name
- NCT05614544
- Testing
- HSK3486, Propofol
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Haisco-USA Pharmaceuticals, Inc.
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