Clinical trials: Injections
Relapsing-remitting Multiple Sclerosis (rrMS)
Assess Safety, Bio-distribution, Radiation Dosimetry and Optimize the Imaging Protocol of GEH120714 (18F) Injection in Healthy Volunteers and Participants With Relapsing and Remitting Multiple Sclerosis (rrMS).
To evaluate the safety, bio-distribution, and radiation dosimetry; and to optimize the Imaging Protocol of GEH120714 (18F) Injection.
- Trial name
- NCT01738347
- Testing
- Arm 1 - GEH120714 (18F) Injection
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Rabies Human, Antibody Titer
Vaccine Prevention of Rabies Adopts 4-shot Immunization Method
A phase III clinical trial to evaluate the immunogenicity and safety of freeze-dried human rabies vaccine (Vero cell) developed by Changchun Zhuoyi Biological Co., Ltd. inoculated in a 4-dose procedure (2-1-1)
- Trial name
- NCT05549908
- Testing
- rabies vaccine
- Where
- China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Changchun Zhuoyi Biological Co., Ltd
Healthy
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Following Subcutaneous Injection of JNJ-64304500 in Healthy Japanese and Caucasian Male Participants
The primary purpose of this study is to assess the safety, tolerability, and pharmacokinetics (PK) following single-dose subcutaneous (SC) injection of JNJ-64304500 in healthy Japanese male participants.
- Trial name
- NCT03002025
- Testing
- JNJ-64304500
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutical K.K.
Virus Diseases, Hepatitis B
Pilot Safety Study to Determine the Ability of the Protector Cap Jet Injector to Prevent Cross-Contamination
The primary purpose of this study is to determine the ability of the Protector Cap Jet Injector to prevent cross-contamination in the next injection sample.
- Trial name
- NCT00219453
- Testing
- Jet Injector with Protector Cap (HSI-500)
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- PATH
Healthy
A Study of Benzathine Benzylpenicillin Intramuscular Injection in Japanese Healthy Subjects
This will be an open label study to investigate the pharmacokinetics (PK) and safety of a single intramuscular injection of penicillin G benzathine in Japanese healthy subjects.
- Trial name
- NCT03612557
- Testing
- penicillin G benzathine
- Where
- Japan
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Pfizer
Subcutaneous Fat
A Study to Evaluate the Efficacy, Safety, and Tolerability of CBL-514 Injection for Reducing Subcutaneous Fat (Stage 2)
The Stage 2 of this phase 2 study will be a randomized, single-blind, placebo-controlled, parallel, and multiple-dose study to assess the efficacy, safety, and subject satisfaction of CBL-514.
- Trial name
- NCT04897412
- Testing
- CBL-514 Injection
- Where
- 5 sites in United States, Australia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Caliway Biopharmaceuticals Co., Ltd.
Obesity/Overweight
Study of Pharmacokinetics and Safety of GZR18 Injection in Subjects With Liver Insufficiency and Normal Liver Function
This study adopts a multicenter, single-dose, open-label, and parallel design, which is aimed at assessing the PK and safety profiles of GZR18 Injection in subjects with normal liver function and those with mild, moderate or…
- Trial name
- NCT07144098
- Testing
- GZR18 injection
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gan & Lee Pharmaceuticals.
Peridontal Disease
Efficacy of Injectable Platelet-rich Fibrin Versus Platelet-Rich Plasma As Adjunctive to Scaling and Root Planning in Non-surgical Periodontal Therapy of Periodontitis Patients
The study aims to evaluate the Efficacy of Injectable Platelet-rich Fibrin versus Platelet-Rich Plasma as adjunctive to scaling and root planning in non-surgical periodontal therapy of Periodontitis patients (Randomized…
- Trial name
- PRP-IPRF (NCT06685393)
- Testing
- Platelet rich plasma (PRP), INJECTABLE PLATELET RICH FIBRIN(I-PRF)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ELsabbahy Ahmed Mohamed Youssef
Nursing Education, Intramuscular Injection
Gamified Metaverse Education for Ventrogluteal IM Injection (G-META-IM)
This study aims to examine the effect of a gamified, metaverse-based education program on nursing students' knowledge and attitudes regarding ventrogluteal intramuscular injection.
- Conditions
- Nursing Education, Intramuscular Injection, Metaverse
- Trial name
- G-META-IM (NCT07396207)
- Testing
- Gamified Metaverse-Based Education Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Propofol Adverse Reaction
Lignocaine Versus Sodium Bicarbonate on Reducing Pain During Propofol Injection
To compare the effect of adding lignocaine and sodium bicarbonate to propofol in reducing pain on propofol injection (POPI).
- Trial name
- NCT05486819
- Testing
- Propofol Injection
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Cairo University
Levator Ani Syndrome With Pain and/or Constipation Symptoms.
Comparison of Biofeedback vs. Botox Injection to Treat Levator Ani Syndrome
Purpose: To assess whether EMG directed biofeedback therapy or Botulinum toxin type A injection of the levator ani muscles has any effect on pain from the levator ani syndrome, and, in addition, to what extent either treatment is…
- Trial name
- NCT00564707
- Testing
- Biofeedback therapy, Botulinum Toxin Type A Injection
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Rheumatoid Arthritis
A Trial With Humanized TNFα Monoclonal Antibody Injection by Single Dose and Dose Escalation in Healthy Subjects
This study is a randomized, double-blind and placebo-controlled trial with healthy subjects. There are 6 Groups as follows: 5mg, 15mg, 30mg, 50mg, 75mg, 100mg, and each group includes12 people.
- Trial name
- NCT02460393
- Testing
- Humanized TNFα monoclonal antibody
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shenyang Sunshine Pharmaceutical Co., LTD.
Chondromalacia, Osteoarthritis
Efficacy of Intra-articular Collagen Injection in Patients With Knee Joint Pain Compared to Normal Saline Injection
The primary objective of this study is to confirm the superiority of intra-articular collagen injection in patients with knee joint pain compared to the control group.
- Conditions
- Chondromalacia, Osteoarthritis, Traumatic Arthritis
- Trial name
- NCT02539095
- Testing
- CartiZol, Normal saline
- Where
- 5 sites in South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Pain
Intravitreal Injection Site and Perceived Pain
The objective of this study is to explore the perception of pain during intravitreal injection related to the distance of the entry site from the limbus.
- Trial name
- NCT05640895
- Testing
- Intravitreal injection site
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Androgenetic Alopecia, Male Pattern Baldness
A Study to Evaluate and Compare Injections of Autologous Dermal and Epidermal Cells Into the Balding Scalp of Subjects With Hair Loss (CA-0002899)
Evaluate the ability of injections of Ji Gami(TM) and Ji Gami(TM) DO to induce hair growth in male and female subjects with hair loss.
- Conditions
- Androgenetic Alopecia, Male Pattern Baldness, Female Pattern Baldness
- Trial name
- NCT01451112
- Testing
- Autologous cultured dermal and epidermal cells
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aderans Research Institute
Needlestick Injuries
The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic
The aim of the study is to find a simple method for pain reduction that can be used in clinical practice when administering digital nerve block with a single subcutaneous injection.
- Trial name
- NCT02086292
- Testing
- 2 ml 1% Lidocaine, 1 ml 2% Lidocaine
- Where
- Norway
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Osteoarthritis, Knee
Parabens Flocculation on the Anti Inflammatory Effects of Corticosteroid Injections for Total Knee Arthroplasty
The purpose of this study is to identify whether corticosteroid use with anesthetics containing preservatives (parabens) reduces clinical effectiveness of the anti-inflammatory agent Up to 100 patients, both male and female…
- Trial name
- 5160373 (NCT03445611)
- Testing
- corticosteroid solution with lidocaine containing parabens., corticosteroid solution with lidocaine containing no paraben
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
HIV
A Phase 1 Trial to Evaluate CAP256V2LS in Healthy Adults
Background: HIV is a serious disease with no cure or vaccine to prevent it. Using antibodies could be a way to prevent HIV infection. Antibodies are made by the human body to fight germs.
- Trial name
- VRC 611 (NCT04408963)
- Testing
- VRC-HIVMAB0102-00-AB
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Injectable Plasma-rich Fibrin Versus Low-Level Laser Therapy on Othodontic Movement
Assessment of Different Orthodontic Tooth Movements Assisted With Low-level Laser Therapy vs. Injectable Platelets-rich Fibrin
The present prospective clinical study will be undertaken for assessment of the effect of application of Injectable plasma-rich fibrin versus Low-Level Laser Therapy onthe rate of different orthodontic tooth movements,
- Trial name
- NCT05966987
- Testing
- Low-level Laser Therapy vs. Injectable Platelets-rich Fibrin
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Cancer Cachexia, Cancer Cachexia Syndrome
The First in Human Study of QLS2319 in Healthy Subjects and Cancer Cachexia
Study To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of QLS2319 in Healthy Subjects and Cancer Cachexia
- Trial name
- NCT07735104
- Testing
- QLS2319
- Where
- 2 sites in China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
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