Clinical trials: Injuries
Dental Anxiety, Dental Phobia
Virtual Reality Distraction for Dental Anxiety (RCT)
The aim of this randomized clinical trial is to verify the efficacy of VR immersion over a muted cartoon on a wall-mounted TV to decrease dental fear and anxiety of children undergoing dental procedures.
- Conditions
- Dental Anxiety, Dental Phobia, Dental Trauma, Dental Diseases
- Trial name
- NCT06182462
- Testing
- Virtual Reality Distraction, Dental Clinic's Standard Treatment
- Where
- Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Traumatic Brain Injury
Effects of Intravascular Administration of Mesenchymal Stromal Cells Derived from Wharton's Jelly of the Umbilical Cord on Systemic Immunomodulation and Neuroinflammation After Traumatic Brain Injury.
Traumatic brain injuries (TBI) are one of the leading causes of death and disability worldwide. These patients are burdened by physical, cognitive, and psychosocial deficits, leading to an important economic impact for society.
- Trial name
- TRAUMACELL (NCT06146062)
- Testing
- Mesenchymal Stromal Cells (MSC)
- Where
- 3 sites in France
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Back Pain, Back Strain Lower Back
Efficacy of Postural Reeducation in Elite Gymnasts With Back Pain
Introduction: Low back pain is a musculoskeletal disorder that is associated with symptoms such as pain, limitation of joint range and postural problems in athletes.
- Conditions
- Back Pain, Back Strain Lower Back, Athletic Injuries
- Trial name
- NCT05149703
- Testing
- Mezieres Postural Treatment
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Dental Implant Failed, Bone Fracture
Alveolar Ridges Expansion Using Osseodensification Versus Screw Expansion Technique
Alveolar ridge expansion is suggested for alveolar crest thicknesses of 3-5 mm. Osseodensification (OD) and screw expansion (SE) techniques have been utilized to expand narrow alveolar ridges (NAR).
- Conditions
- Dental Implant Failed, Bone Fracture, Bone Infection
- Trial name
- NCT05895903
- Testing
- Screw expander, Osseodensification drills
- Where
- Iraq
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Risk Reduction Behavior, Injuries
Driver Education Research Study
This study will test the effectiveness of different types of driver training interventions for reducing young new driver crash risk early after licensure.
- Conditions
- Risk Reduction Behavior, Injuries, Accident, Traffic, Development, Adolescent
- Trial name
- DRIVER (NCT06413927)
- Testing
- Online Vehicle and Driver Safety Education, Online Driver Skills Training, Behind-the-Wheel Driver Training
- Where
- United States
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Post-operative Cognitive Dysfunction
Target Hemodynamics and Brain Injury During General Anesthesia in the Elderly
BACKGROUND: Post-operative cognitive dysfunction (POCD) is a potentially irreversible loss of brain functions observed in elderly patients after surgical operations under general anaesthesia.
- Trial name
- THE BRIDGE (NCT02428062)
- Testing
- Hemodynamic target, Phenylephrine, Intravenous fluids
- Where
- Italy
- Volunteers
- 1,812 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Hand Injuries
Three-dimensional Kinematic Motion Analysis of Finger and Wrist During Daily Activities
Development of reliable and objective evaluation methods is required for natural upper-extremity tasks. Three-dimensional imaging measurement techniques are a powerful tool for quantitative assessment of multijoint movements.
- Trial name
- NCT02890862
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hip Fractures
Effects of S-ketamine and Continuous Iliac Fascia Space Block on Perioperative Neurological Cognitive Impairment and Postoperative Rehabilitation in Elderly Patients With Hip Fracture
Elderly patients with hip fracture are older and have a high incidence of perioperative complications. the postoperative recovery of elderly patients with hip fracture is affected by hemodynamic instability and pain caused by…
- Trial name
- NCT05304559
- Testing
- S-Ketamine, Continuous iliac fascia space block, Normal saline
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Cesarean Wound Disruption
The Influence of Endometrial Suturing on the Risk of Uterine Scar Defect
Caesarean section (CS) is the commonest major operation performed on women worldwide with progressively rising incidence. Consequently, long-term adverse sequelae due to uterine scar defect have been increasing.
- Trial name
- NCT03851003
- Testing
- Endometrial suturing, Non- endometrial suturing, Vaginal ultrasonography
- Where
- Israel
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Scleroderma, Systemic
Role of Circulating Cytotoxic Lymphocytes in Endothelial Cell Injury in Systemic Sclerosis
Systemic Sclerosis (SSc) is an auto-immune systemic disease characterized by vascular damage, cutaneous and visceral fibrosis and a dysimmune condition.
- Trial name
- NCT02636127
- Testing
- blood samples
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Palate; Wound, Wound Heal
Comparison of Palatal Wound Healing in Diabetic and Non-diabetic Patients
This study aims to characterize and compare the closure of open wounds in the palatal mucosa of diabetic and non-diabetic patients, evaluate clinical, patient-centered and immunological parameters as well as wound microbiome…
- Conditions
- Palate; Wound, Wound Heal, Diabetes
- Trial name
- NCT06540690
- Testing
- Palatal Wound
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Recurrent Patellar Dislocation, Patellar Instability
The Comprehensive Assessment in Children After Surgical Treatment of Patellar Recurrent Dislocation.
The aim of this prospective study is to assess extension apparatus function of the knee based on clinical, radiological, isokinetic and gait analysis data in patients after surgical treatment.
- Trial name
- NCT03983213
- Testing
- mpfl reconstruction
- Where
- Poland
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Polish Mother Memorial Hospital Research Institute
Muscle Injury
Vacuum Myofascial Therapy Device in Treatment of Muscle Fibrosis
We present the case of a 24-year-old professional soccer player, with no personal history of interest, who came to the X-Ray diagnosis service due to severe pain in the right quadriceps muscle after a 10-month evolution of muscle…
- Trial name
- Physium (NCT04352920)
- Testing
- Experimental group
- Where
- Spain
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Knee Pain Chronic, Knee Injuries
Treatment of Knee Pain With Topical Diclofenac Cream 8% or Diclofenac Gel 1%
Non-steroidal anti-inflammatory medication (NSAID) therapy is a mainstay treatment for joint pain and painful musculoskeletal disorders.
- Trial name
- NCT02068859
- Testing
- Diclofenac Cream 8%, Diclofenac Gel 1%
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- FPR Specialty Pharmacy
Traumatic Knee Arthrotomy
Sensitivity Diagnosing Traumatic Knee Injuries With and Without Injection of Blue Dye Into the Knee Joint
The purpose of this study is to determine if adding blue dye improves the saline load test, which is a way to detect a traumatic intraarticular knee injury by injecting normal saline into the knee and looking for outflow through…
- Trial name
- NCT01073124
- Testing
- Saline Load Test
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Healthy
A Clinical Study to Explore Biomarkers for Drug-induced Liver Injury (DILI)
This study has an open-label, one-sequence, multiple drug administration design. The purpose of this study is as follows; To evaluate the change of liver function according to glutathione s-transferase (GST) genotype after the…
- Trial name
- NCT02143323
- Testing
- Augmentin tablet
- Where
- 2 sites in South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Spinal Cord Injuries
Functional Interval Training for People With Spinal Cord Injury and Their Care Partners
Functional Interval Training for People with Spinal Cord Injury and Their Care Partners (SCI-FIT) aims to address barriers to physical activity for people with spinal cord injury and their care partners.
- Trial name
- SCI-FIT (NCT05221723)
- Testing
- High Intensity Interval Exercise Training Group
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Wound Healing
Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: Vacuum Assisted Closure (VAC) and Gauze Suction (GSUC)
The purpose of this study is to compare how well two methods (VAC and G-SUC) of securing skin grafts using negative pressure wound therapy work.
- Trial name
- NCT00952120
- Testing
- GSUC, VAC
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Chronic Lateral Epicondylosis
PEAK Platelet Rich Plasma Injection Treatment for Chronic Lateral Epicondylosis
The proposed project will be the first to assess pain- and function-dependent, elbow-specific quality of life and in-vivo mechanical properties of common extensor tendons post-treatment with PRP in a Level 1, RCT with subject and…
- Trial name
- NCT03072381
- Testing
- Platelet Rich Plasma - Group 1, Corticosteroid Control - Group 2
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Decompression Sickness
NASA Exercise Prebreathe Study
This study evaluates oxygen prebreathe protocols and exercise conditions to reduce risk of decompression sickness during simulated extravehicular activity.
- Trial name
- NCT07702539
- Testing
- Oxygen Prebreathe and Hypobaric Exposure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Duke University
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