Clinical trials: Insulin Response
Blood Glucose, Postprandial, Blood Insulin, Postprandial
Effects of Berries on Post-meal Blood Sugar
The purpose of this study is to investigate whether berries are effective in lowering blood glucose and insulin responses to meals containing starch or sucrose.
- Conditions
- Blood Glucose, Postprandial, Blood Insulin, Postprandial, Hyperglycemia
- Trial name
- SOMA (NCT01580150)
- Testing
- Berries, No berries
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marjukka Kolehmainen
Type 1 Diabetes
Suppression of Endogenous Glucose Production by Injectable HDV-Insulin Lispro: A Dose Response Study in Human Subjects With Type 1 Diabetes
Single-center, double-blind, random-sequence study assessing the HDV dose-response relationship to Endogenous Glucose Production (EGP), Free Fatty Acids (FFA) and Glucose Disposal Rate (GDR) during a euglycemic clamp procedure…
- Trial name
- NCT05689424
- Testing
- HDV-Insulin Lispro
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Insulin Resistance
Cardiovascular and Metabolic Responses to a Mixed Meal
The purpose is to determine whether regular endurance exercise and/or body weight influence the way our nervous and vascular systems respond during the metabolism of meals.
- Trial name
- NCT00882986
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- John Thyfault
Insulin Response, Type 1 Diabetes
Advancing Precision Nutrition: Wearable Technology for Noninvasive Insulin Monitoring
Noninvasively monitoring insulin is crucial for advancing precision nutrition and promoting healthy living by enabling a deeper understanding of individual metabolic responses to dietary intake.
- Trial name
- NCT07254364
- Testing
- Standardized meal 1
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Glucose Levels, Lipid Profile
Effects of Fasted- Versus Fed-exercise on Metabolic Health in Physically Active Adults
The purpose of this study is to investigate whether the sequence meal and exercise (exercise before meal or exercise after meal) affects the postprandial metabolism.
- Conditions
- Glucose Levels, Lipid Profile, Substrate Oxidation, Blood Pressure
- Trial name
- NCT06949709
- Testing
- Fasted-exercise, Fed-exercise
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Blood Glucose; Subjective Hunger, Insulin
Glycemic and Insulinemic Impact of Oats With Additional Dried Fruits, Nuts and Seeds Soaked Overnight
The purpose of this study is to compare the glucose, insulin and subjective hunger responses elicited by oats with additional dried fruits, nuts and seeds soaked overnight in skim milk and consumed cold versus Cream of Rice…
- Trial name
- NCT03091946
- Testing
- Overnight oats with additional dried fruits, nuts and seeds, Cooked cream of rice with additional dried fruits, nuts and seeds
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Pharmacodynamic Response to Small Doses of Insulin
Transdermal Insulin Response In Healthy Volunteers
Bio-fermentation produced Human insulin is available without prescription in the U.S. This study is a physician-initiated trial of a formula enabling transdermal delivery of human insulin.
- Trial name
- NCT04857320
- Testing
- Human insulin
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Transdermal Delivery Solutions Corp
Obesity
Acylated Ghrelin Response to Acute Exercise in Obesity
Ghrelin is a GH-secretagogue gastrointestinal hormone that regulates feeding behavior by interacting directly with hypothalamic centers in concert with other negative and permissive neuromodulators.
- Trial name
- aeroghre (NCT00486161)
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Obesity, Weight Loss
Weight Loss Study-Mechanism Underlying the Improvement of Insulin Resistance in Response to Weight Loss
The main purpose of this study is to assess factors mediating the changes in insulin sensitivity and glucose tolerance before and after 10 lbs ± or 2% weight loss reduction as well as 2, 3, 6, 12, and 24 months after initiation…
- Trial name
- NCT01780870
- Testing
- Weight loss group (Full meal replacement products)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Type 2 Diabetes, Insulin Resistance
The Effects of Two Days of Bedrest on Insulin Resistance in Type 2 Diabetics
The hypothesis of this study is that bed rest in diabetic patients will result in a deterioration of metabolic control (primarily glucose). Specific aims: 1.
- Trial name
- NCT00508599
- Testing
- Study 2 (48 hours of complete bed rest)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Type 2 Diabetes, Healthy
Type 2 Diabetes and the Effect of Probiotics
Insulin-resistance in type 2 diabetes is associated with chronic inflammation. Anti-inflammatory actions might increase sensitivity to insulin.
- Conditions
- Type 2 Diabetes, Healthy, Endotoxemia
- Trial name
- NCT00413348
- Testing
- Lactobacillus acidophilus NCFM
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diabetes Mellitus, Type 2
Effect of LY2189265 on Insulin Secretion in Response to Intravenous Glucose
The purpose of this study is to measure the effect of LY2189265 to increase insulin levels in response to glucose intake.
- Trial name
- NCT01300260
- Testing
- LY2189265, Insulin, Glucose
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Healthy
A Dose-response Study Examining the Contribution of GLP-1 Receptor Signaling to Glucagon-stimulated Insulin Secretion
The GLP-1 receptor (GLP1R) gene is found on the beta cells of the pancreas. Its role is in the control of blood sugar level by enhancing insulin secretion from the pancreas after eating a meal.
- Trial name
- NCT04459338
- Testing
- Exendin-9,39, Saline
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Adrian Vella
Type 1 Diabetes Mellitus
A Study of How Insulin Peglispro (LY2605541) and Insulin Glargine Affect the Breakdown of Fat and Sugar in Type 1 Diabetics
This is a two-period study of participants with type 1 diabetes mellitus (T1DM). In each period, participants will receive once daily injections of stable dose LY2605541 or insulin glargine for 28 to 35 days followed by…
- Trial name
- NCT01925989
- Testing
- LY2605541, Insulin Glargine
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Postprandial Hyperglycemia
Determination of the PPG and Insulin Responses of Rice Alone and Rice Consumed With Sugardown™
This study was a partly controlled laboratory-based study comparing the short-term postprandial blood glucose and insulin responses produced by 3 test meals containing white rice alone or with SUGARDOWN™ (Galactomannan) in…
- Trial name
- NCT03375398
- Testing
- Rice, Sugardown™
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston Therapeutics
Healthy, Body Mass Index, Normal
Glycemic Response of Whole Beans and Bean Products
The main goal of this clinical trial is to learn if alpha-galactosidase (tradename Beano) changes in post-prandial (after-meal) blood glucose after eating whole cooked whole pulses or pulse-based pasta products in comparison to…
- Conditions
- Healthy, Body Mass Index, Normal, Postprandial Hyperglycemia
- Trial name
- BH-GLY (NCT06630312)
- Testing
- Alpha galactosidase
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Insulin Resistance, Cardiovascular Disease
Processing Responses of Grains (PRO-Grains) Study
The primary objective of this pilot study will be to examine the effects of consuming whole grains, differing in the degree of processing, on insulin sensitivity and other cardiometabolic risk factors.
- Conditions
- Insulin Resistance, Cardiovascular Disease, Diabetes
- Trial name
- NCT02186353
- Testing
- Partial feeding study
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Insulin Resistance
The Effects of Altering Physical Activity on Cardiometabolic Health
The effects of physical inactivity on variations in blood glucose and vascular health are not fully understood. The purpose of this study is to determine if an acute transition from physical activity to inactivity alters vascular…
- Trial name
- PIA (NCT01879059)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Obesity, Diabetes Mellitus, Type 2
Enteroendocrine Hormonal Response After the Ingestion of Cola Beverages With Sucrose and Non-nutritive Sweeteners
Introduction: The consumption of non-nutritive sweeteners (NNS) has been increasing in recent years, as an alternative to replace sugars and reduce the additional intake of carbohydrates, with the idea of reducing the risk of…
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Metabolic Syndrome
- Trial name
- NCT05654285
- Testing
- Cola beverage with aspartame and acesulfame K, Cola beverage with sucrose and stevia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Artificial Intelligence Mobile Application
Food-i-Sense Analytics: Integrating AI Into Continuous Glucose Monitoring Data Analysis for Precision Nutrition.
This study aims to improve how we understand and manage blood sugar responses in adults without diabetes. Even in people who appear healthy, blood sugar levels after meals can behave in different ways.
- Trial name
- Food_i Sense (NCT07626658)
- Testing
- Continuous glucose monitoring using a wearable sensor (flash interstitial glucose monitor)
- Where
- Spain
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- IMDEA Food