Clinical trials: Intense Exercise, open to volunteers
Atrial Fibrillation (AF), Atrial Fibrillation (Paroxysmal)
PREACTIVE: Preconditioning Exercise Intervention to Improve Symptoms and Quality of Life in Comorbid Atrial Fibrillation and HFpEF
Atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) are very common conditions that often occur together and result in worsening symptoms and reduced quality of life (QoL).
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation (Paroxysmal), Persistent Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction (HFPEF)
- Trial name
- PREACTIVE (NCT07324772)
- Testing
- progressive resistance training, combined aerobic + resistance training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Healthy Adult Male and Female Volunteers, Intervention
Exploring Resistance Exercise Training Plus High-Intensity Interval Training (ReHIIT) as Cancer Prehabilitation
Colorectal cancer is the fourth most common cancer in the UK. Prehabilitation, including exercise, can improve recovery from surgery.
- Trial name
- ReHIIT_CON (NCT07313332)
- Testing
- ReHIIT Training Intervention
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Chronic Low-back Pain, Exercise Therapy
Technology Supported High Intensity Training in Chronic Low Back Pain: the Techno-HIT Trial
Chronic low back pain (CLBP) is one of the most common chronic musculoskeletal disorder worldwide and is responsible for the highest levels of disability of all diseases.
- Conditions
- Chronic Low-back Pain, Exercise Therapy, Telerehabilitation
- Trial name
- TECHNO-HIT (NCT06491121)
- Testing
- Technology supported High Intensity Training, Moderate Intensity Training, High Intensity Training
- Where
- 4 sites in Belgium
- Volunteers
- 168 people
- Sponsor
- Hasselt University
Hemiplegia and/or Hemiparesis Following Stroke
High-Intensity Laser Therapy in Hemiplegic Shoulder Pain
This randomized, sham-controlled clinical trial aims to evaluate the effectiveness of high-intensity laser therapy (HILT) combined with exercise on pain, functional status, disability, and ultrasonographic findings in patients…
- Trial name
- NCT07501416
- Testing
- High-Intensity Laser Therapy (HILT), Exercise therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kutahya Health Sciences University
High Intensity Interval Training, Heart Failure
Effects of Upper Extremity Low Volume HIIT in Heart Failure
This study was planned to investigate the effects of upper extremity low-volume high-intensity interval training (LV-HIIT) on physical and cognitive function in patients with heart failure with preserved ejection…
- Conditions
- High Intensity Interval Training, Heart Failure, Exercises
- Trial name
- NCT06754475
- Testing
- Low-volume, high-intensity interval training, Standart medical treatment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Tarsus University
Physical Activity, Energy Intake
Effects of Different Timing of Bodyweight High-intensity Exercise on Human Behaviours
The purpose of this project is to investigate the effects of exercise at different times of day on 72-hour eating behaviour, physical activity and sedentary behaviour in physically inactive adults.
- Conditions
- Physical Activity, Energy Intake, Sedentary Behavior
- Trial name
- NCT06966414
- Testing
- Morning exercise, Evening exercise
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Functional Constipation (FC)
Implementation of Physical Therapy Protocol for Functional Constipation
The goal of this randomized controlled trial is to investigate the effects of standard medical treatment alone and the effects of adding different physiotherapy protocols to standard medical treatment on constipation severity…
- Trial name
- NCT07719504
- Testing
- Standard medical treatment, Maitland orthopedic manual therapy (MOMT), Russian current stimulation (ERS)
- Volunteers
- 60 people
- Sponsor
- Cairo University
Cognitive Impairment
The Effect of Upper Limb Low-intensity Motor Control Training Program on Cognitive Function in Healthy Older Adults
This healthy volunteer intervention study is designed to evaluate the effectiveness of upper limb motor control training (uMCT) on physical and cognitive functions in older adults.
- Trial name
- uMCON (NCT06962722)
- Testing
- Upper limb motor control training (uMCON)
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Overweight and/or Obesity
Effects of Whole-Body High-Intensity Interval Training on Fitness in Overweight Adults
This study aims to evaluate the effects of a supervised whole-body high-intensity interval training (WB-HIIT) program on physical fitness and health outcomes in adults with overweight and obesity.
- Trial name
- WB-HIIT (NCT07582718)
- Testing
- Whole-Body High-Intensity Interval Training (WB-HIIT)
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Université Libre de Bruxelles
Aging, Frailty
Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults
This is a randomized, double-blind, placebo-controlled, two-arm crossover clinical trial evaluating the effects of nicotinamide mononucleotide (NMN) combined with trimethylglycine (TMG) supplementation, compared to NMN alone.
- Conditions
- Aging, Frailty, Exercise Tolerance, Healthy Male and Female Subjects
- Trial name
- NCT07144527
- Testing
- NMN and TMG (Euexia), Nicotinamide Mononucleotide (NMN)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Scott Silveira
Obesity, NAFLD
Vigorous- Versus Moderate-intensity Exercise to Reduce Liver Fat in Adults With Obesity and NAFLD
Non-alcoholic fatty liver disease (NAFLD) arising from obesity has become a global health concern. Although exercise is a cornerstone approach for managing NAFLD, detailed exercise prescription guidelines are unavailable.
- Trial name
- NCT06124456
- Testing
- Usual Care Control Group, Moderate-intensity Exercise Intervention, Vigorous-intensity Exercise Intervention
- Where
- Hong Kong
- Volunteers
- 330 people
- Sponsor
- The University of Hong Kong
Acute Effects of Exercise in Healthy People, Health Adult Subjects
Acute Effects of Aerobic Exercise and High-intensity Interval Exercise With Immersive Virtual Reality
This study aims to compare the acute effects at the cardiovascular (heart rate, blood pressure) and physiological (lactate) levels, as well as the perception of effort and fatigue, of four exercise modalities, one based on the…
- Trial name
- NCT07101341
- Testing
- Traditional aerobic training, High Intensity Interval Training (HIIT), Aerobic training performed with a immersive virtual reality application
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Glucose Control
The Effect of High-Intensity Short-Duration Exercise Versus Moderate-Intensity High-Volume Exercise on Glucose Control
This study will be conducted as a prospective, randomized crossover trial evaluating non-diabetic and pre-diabetic adults ($n=12$) continuously monitored with Dexcom G7 continuous glucose monitors over an 11-day period.
- Trial name
- NCT07829042
- Testing
- High Intensity Interval Training, Moderate Intensity aerobic training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Type 1 Diabetes (T1D)
Exercising in Hot Conditions: How Does it Effect Blood Glucose in People With T1D
A randomised, crossover, counterbalanced repeated measures study will be conducted to examine the effect of acute heat exposure on rate of change in blood glucose concentration during 40 minutes of moderate-intensity exercise and…
- Trial name
- T1D-Heat (NCT07341243)
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 38 people
- Sponsor
- Liverpool John Moores University
Stroke
Does High-intensity Exercise Lead to Better Functional Outcomes Early After Stroke in an Inpatient Rehabilitation Setting?
The purpose of this study is to find out the effectiveness of high intensity exercise (HIE) early after stroke, this study is hoping to recruit 36 participants in total and will be analysing pre- and post- outcomes of patients in…
- Trial name
- NCT06913127
- Testing
- High intensity exercise post stroke
- Where
- Singapore
- Volunteers
- 36 people
- Sponsor
- Mah Shi Min
Aging, High-intensity Interval Training
Can Exercise Ameliorate Immunosenescence and Thereby Reduce Relapse in Head and Neck Cancer Patients
Through the implementation of this three-year project, investigators expect to find a safe and effective exercise prescription for patients with oral cancer after surgery.
- Conditions
- Aging, High-intensity Interval Training, Head and Neck Cancers - Tonsils
- Trial name
- NCT06851988
- Testing
- HIIT & Record of physical activities at home., HIIT only
- Where
- Taiwan
- Volunteers
- 290 people
- Sponsor
- Chang Gung Memorial Hospital
Energy Metabolism, Exercise
Energy Cost and Metabolic Intensity of Pilates Exercises in Older Adults
Pilates is one of the most popular forms of exercise among older adults worldwide. However, no study has measured how many calories a Pilates session burns or how hard the body works during it in people aged 60 and over.
- Conditions
- Energy Metabolism, Exercise, Aging
- Trial name
- NCT07621523
- Testing
- Mat Pilates, Equipment-Based Pilates, Treadmill Walking
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Norte do Parana
HIV, Arterial Stiffness
High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV
This is a single site, randomized exercise trial with individuals at least 50 years of age living with HIV who experience suboptimal cognition.
- Conditions
- HIV, Arterial Stiffness, Cognitive Dysfunction
- Trial name
- NCT05965518
- Testing
- High-Intensity Interval Training, Continuous Moderate Exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Type 2 Diabetes
Acute Effect of Tai Chi Versus Moderate-Intensity Combined Exercise on Cardiovascular, Metabolic, and Cardiac Autonomic Control Parameters in Older Men and Women With Type 2 Diabetes Mellitus
Type 2 diabetes mellitus (T2DM) in the elderly population is associated with compromised cardiovascular and metabolic functions, thereby necessitating the implementation of safe exercise interventions.
- Trial name
- NCT07113444
- Testing
- Tai Chi, Moderate-Intensity Combined Exercise (MICE), Control ( No Exercise )
- Volunteers
- 24 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Exercise Training, Breast Cancer
Moderate-Intensity Exercise and Pain Sensitization in Breast Cancer Survivors: A Case-Based Study
The aim of this study was to evaluate the feasibility, safety, and acceptability of a supervised, combined moderate-intensity aerobic and resistance training program designed to reduce pain sensitization in BCS with persistent…
- Conditions
- Exercise Training, Breast Cancer, Pain Management
- Trial name
- NCT07128030
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Rey Juan Carlos