Clinical trials: Interaction
Schizophrenia
Interactions of Fronto-Parietal High Frequency rTMS on Anterior Cingulate Cortex Activation in Schizophrenia
This will be a single site pilot study. 20 subjects with EPP (Early Phase Psychosis), defined as medical record documentation of the onset of clinically significant psychotic symptoms within the past 10 years, will be enrolled.
- Trial name
- rTMS-FPCC (NCT04309370)
- Testing
- 20 Hz rTMS
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Indiana University
HIV Infections, Malaria
Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected Patients
Malarone® (atovaquone/proguanil) is frequently used in malaria prophylaxis. Unfortunately, there are indications that certain anti-HIV agents may decrease atovaquone plasma levels by induction of atovaquone metabolism.
- Trial name
- NCT00421473
- Testing
- Atovaquone / Proguanil
- Where
- 5 sites in Netherlands
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Drug-drug Interaction Study
Drug-drug Interaction Study of Rifampin and Anaprazole Sodium
A drug-drug interaction study designed to evaluate the drug-drug interaction between rifampin capsules and anaprazole sodium enteric-coated tablets in healthy adult subjects
- Trial name
- NCT07330531
- Testing
- Anelazol Sodium Enteric-coated Tablets, Rifampicin Capsules
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Xuanzhu Biopharmaceutical Co., Ltd.
Nursing Diagnosis, Psychosocial Diagnoses
Blended Learning for Psychosocial Nursing Diagnoses
The nursing process is a systematic approach forming the basis of professional nursing care. Literature indicates that nursing students experience the most difficulty in determining nursing diagnoses, often focusing predominantly…
- Conditions
- Nursing Diagnosis, Psychosocial Diagnoses, Psychosocial Care
- Trial name
- NCT07670351
- Testing
- Case-Based Blended Learning Module
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Bacterial Infections
P1, DDI & MAD PK and Safety Study of Xeruborbactam Oral Prodrug in Combo With Ceftibuten in Healthy Participants
A Phase 1, Open-Label, Drug-drug Interaction, and Randomized, Double-blind, Controlled, Multiple-dose Pharmacokinetics and Safety Study of Xeruborbactam Oral Prodrug (QPX7831) in Combination with Ceftibuten in Healthy Adult…
- Trial name
- NCT06079775
- Testing
- Xeruborbactam Oral Prodrug, Ceftibuten
- Where
- Australia
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Qpex Biopharma, Inc.
Autism, Autism Spectrum Disorder
Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions
This study is a 12-week randomized-controlled trial of memantine hydrochloride (Namenda) for the treatment of social impairment in youth with Non-Verbal Learning Disorder, High-Functioning Autism Spectrum Disorder, and related…
- Conditions
- Autism, Autism Spectrum Disorder, Nonverbal Learning Disability
- Trial name
- NCT03553875
- Testing
- Memantine Hydrochloride
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Hemiparetic Stroke
Integration and Interactions Between Visual and Proprioceptive Feedbacks
Mental imagery is a rehabilitation technique for stroke patients, involving the mental representation of movement. Recent technical advancements have enabled the use of visual, proprioceptive, and mixed feedback to enhance motor…
- Trial name
- OptiVis (NCT06931509)
- Testing
- Computerized mirror therapy (IVS3) + Tendon vibration (Vibramoov)
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Hiv
Efficacy Trial of Life Simulation Game to Routinize Adolescent HIV Testing
This study will aim to assess the acceptability, usability and efficacy of using state-of-the-art video game technology to increase HIV testing among adolescents and young adults (AYA) ages 13-24.
- Trial name
- NCT04917575
- Testing
- Mobile Game, Mobile Application
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- George Washington University
Healthy
Comparative Effects of Azithromycin, Telithromycin and Levofloxacin on Drug Metabolizing Enzymes
Studies have previously shown that a broad drug interaction screening can be performed using enzyme specific probes such as oral caffeine for CYP1A2, N-acetyltrasferase-2 (NAT-2), and xanthine oxidase (XO), warfarin plus vitamin…
- Trial name
- NCT00164112
- Testing
- Cooperstown 5+1 alone, Azithromycin plus Cooperstown 5+1, Telithromycin plus Cooperstown 5+1
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bassett Healthcare
Cognitive Decline Prevention in Robust Older Adults, Cognitive Decline Prevention in Pre-frail Older Adults
The StayFitLonger Study: an Innovative Computerized Home-based Training to Foster Independent Life at Home
Multimodal training, including physical and cognitive activities, has been associated with a reduction in age-related physical and cognitive decline.
- Conditions
- Cognitive Decline Prevention in Robust Older Adults, Cognitive Decline Prevention in Pre-frail Older Adults, Physical Decline Prevention in Robust Older Adults, Physical Decline Prevention in Pre-frail Older Adults
- Trial name
- SFL (NCT04237519)
- Testing
- SFL training, Active controlled training
- Where
- 4 sites in Belgium, Canada and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Type 2 Diabetes Mellitus
Interaction Study SLV337/Simvastatin
To investigate the effect of multiple doses of SLV337 on the pharmacokinetics of simvastatin and simvastatin acid when co-administered in healthy male subjects
- Trial name
- NCT00924430
- Testing
- Simvastatin- SLV337 SD beta- SLV337 SD alpha - SLV337 MD beta- SLV337 SD beta+ Simvastatin, Simvastatin - SLV337 SD alpha - SLV337 SD beta - SLV337 MD beta - SLV337 SD beta+ Simvastatin
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Solvay Pharmaceuticals
Healthy
Pharmacokinetic Study of Primaquine and Dihydroartemisinin-Piperaquine in Healthy Subjects
The observed changes of P. falciparum sensitivity to artemisinin leads to the intensification of early detection as well as treatment monitoring in malaria infection.
- Trial name
- NCT01525511
- Testing
- A, B
- Where
- Thailand
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Methamphetamine Use Disorder
Study of Pomaglumetad and Methamphetamine
This is the first study of pomaglumetad in humans using methamphetamine. The goal of the study is to determine if pomaglumetad is safe when administered with methamphetamine.
- Trial name
- POMA-MA-Ph1 (NCT03106571)
- Testing
- Pomaglumetad methionil, Methamphetamine
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, Los Angeles
Smoking
Computer-Based Program to Facilitate Readiness and Motivation for Smoking Cessation
The current study seeks to use a computer-based program to target parents of children who smoke. Parents will be randomly assigned to either receive personalized feedback about their smoking behaviors or not.
- Trial name
- NCT01326234
- Testing
- Personalized Feedback, Treatment as Usual
- Sponsor
- University of Oklahoma
Healthy
A Drug-Drug Interaction Study of Orforglipron (LY3502970) With Quinidine in Healthy Participants
The purpose of this study is to determine the effect of quinidine on the levels of orforglipron in the blood stream and how long it takes the body to eliminate it, when administered orally in healthy participants.
- Trial name
- NCT06704763
- Testing
- Orforglipron, Midazolam, Quinidine
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Migraine
AI Chatbot for Migraine Management in Hong Kong Women
The goal of this randomized crossover trial is to examine whether the AI-empowered chatbot will effectively collect comprehensive migraine feature data and demonstrate higher compliance, accuracy, utilization, acceptability…
- Trial name
- NCT06920602
- Testing
- AI-empowered voice-interactive chatbot, Paper migraine diary
- Where
- Hong Kong
- Volunteers
- 49 people
- Sponsor
- The Hong Kong Polytechnic University
HIV Infections
The Safety and Effectiveness of U-90152 in HIV-1 Infected Patients Who Take Zidovudine
To evaluate the pharmacokinetics, safety, and tolerance of delavirdine mesylate ( U-90152 ) after multiple doses given orally to asymptomatic HIV-1 positive patients who are maintained on a stable dose of zidovudine ( AZT ).
- Trial name
- NCT00002312
- Testing
- Delavirdine mesylate, Zidovudine
- Where
- United States
- Sponsor
- Pharmacia and Upjohn
Live Face Processing in Typically Developed Participants
Neural Mechanisms of the Social Brain
This study aims to understand the neural mechanisms that underlie synchronization of two brains during social interactions.
- Trial name
- NCT07457567
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yale University
Older Adults
Online Interactive Courses on Loneliness and Quality of Life of Older Adults
Background: The early stage of the COVID-19 pandemic can be marked as a critical period in human history as it increased loneliness in people's lives.
- Trial name
- NCT05007600
- Testing
- Online Interactive Courses
- Where
- Taiwan
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Yang Shang-Yu
COPD Exacerbation, Bronchiectasis With Acute Exacerbation
Multi-omics Studies of Host-microbiome Interaction in Chronic Obstructive Pulmonary Disease and Bronchiectasis
Chronic obstructive pulmonary disease (COPD) and bronchiectasis are common chronic respiratory diseases in China. COPD is characterized by irreversible lung function decline due to airway inflammation, emphysema and alveolar…
- Trial name
- NCT05738044
- Testing
- No intervention
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ruijin Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.