Clinical trials: Intermittent Fasting
Metabolic Syndrome, Obesity and Obesity-related Medical Conditions
Effects of Intermittent Fasting and Exercise on Inflammation, Metabolism, and the Microbiome in Metabolic Syndrome
The goal of this intervention trial is to assess the effects of intermittent fasting, both alone and in combination with high-intensity interval training, on patients with obesity and metabolic syndrome.
- Trial name
- FIT (NCT06885255)
- Testing
- Alternate day fasting, Time restricted eating, High-intensity interval training
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Energy Deficiency Due to Short-term Fasting
Pharmacokinetics of Leptin Administration During Fasting
The purpose of this study will be to determine the correct dose of leptin, a natural hormone secreted by the fat cells, to give to people when they are fasting and also to determine whether giving leptin to a person when he or…
- Trial name
- NCT00140205
- Testing
- r-metHuLeptin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Diet, Healthy, Weight Change, Body
Effects of a Daily Time-Restricted Feeding Protocol on Diet Quality
As a result of unhealthful lifestyle practices including nighttime ingestion and excess energy-dense food and beverage intake, college students are presenting with metabolic abnormalities and excess weight gain that increases…
- Conditions
- Diet, Healthy, Weight Change, Body, Dyslipidemias, Blood Pressure
- Trial name
- NCT04348019
- Testing
- Fasting
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Obesity & Overweight, Gut -Microbiota
Effects of Monday-Thursday Sunnah Fasting on Short-Chain Fatty Acids, GLP-1, Satiety, and Nutritional Status in Obese Males
This quasi-experimental study investigated the effects of 8 weeks of Monday-Thursday Sunnah fasting on fecal short-chain fatty acids (SCFA), fasting total GLP-1, appetite regulation (hunger and satiety area under the curve)…
- Trial name
- NCT07703865
- Testing
- Monday-Thursday Sunnah Dry Fasting
- Where
- Indonesia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Muhammadiyah Jakarta
Type 2 Diabetes, Insulin Resistance
Intermittent Fasting for Metabolic Health, Does Meal Timing Matter?
Obesity is a serious medical condition, the adverse consequences of which include increased risk of cardiovascular disease, diabetes mellitus, reduced fertility and cancer.
- Trial name
- NCT02633722
- Testing
- Lifestyle intervention B, Lifestyle Intervention D
- Where
- Australia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Weight Loss
Meal Timings, Appetite, Mood and Weight Loss in Individuals on a Commercial Intermittent Fasting Programme
Although individuals following commercial intermittent fasting programmes consume meal replacement products during fasting days, further behavioural variables such as time of food consumption, sleep quality and duration, appetite…
- Trial name
- DASMA (NCT04893772)
- Testing
- Intermittent fasting
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- King's College London
Obesity, Fasting
Investigating the Effect of Short-term Fasting on T Cell Metabolism, Function, and Phenotype in Obesity
The immune system is made up of many types of immune cells, each of which play a specialized role in protecting against pathogens.
- Conditions
- Obesity, Fasting, T-Cell Dysfunction
- Trial name
- NCT05886738
- Testing
- Fasting
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Vaccination, Immunosenescence
VITAL: Vaccination, Immunity, Time-restricted Eating, Aging and Lifestyle
The aim of this study is to investigate the effects of a four-week time-restricted eating (TRE) intervention on autophagy, immune function, and vaccine response to a seasonal influenza and COVID-19 vaccines in older healthy…
- Conditions
- Vaccination, Immunosenescence, Metabolism
- Trial name
- VITAL (NCT07000708)
- Testing
- TRE: Time-restricted eating
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Obesity and Type 2 Diabetes, Metabolic Diseases
Effects of HIIT vs. TRE on Type 2 Diabetes Risk
The primary aim of this randomized controlled trial is to examine the effects of a 4-week high-intensity interval training (HIIT) and time-restricted eating (TRE) intervention on cardiometabolic biomarkers in adolescents and…
- Conditions
- Obesity and Type 2 Diabetes, Metabolic Diseases, High-intensity Interval Training, Time-restricted Eating
- Trial name
- NCT07215533
- Testing
- High-intensity interval training, Time-restricted eating
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Sleep Quality, Compliance
Changes in 24-hour Activity Cycle Behaviors During a Time-Restricted Eating Intervention in College-Aged Women
Time-restricted Eating (TRE) is a dietary approach that limits food intake to 4 - 12-hour windows without intentionally altering diet quality.
- Conditions
- Sleep Quality, Compliance, Physical Activity, Sedentary Behaviors
- Trial name
- DAWG-TREAT (NCT07520786)
- Testing
- Time Restricted Eating, Control
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Healthy
Influence of Meal Skipping on Macronutrient Oxidation and Glucose Metabolism Under Isocaloric Conditions
Aim of the study is to investigate the impact of meal skipping (breakfast or dinner skipping) on the regulation of glucose metabolism and macronutrient balance (protein/fat/carbohydrate intake vs. -oxidation).
- Trial name
- NCT02635139
- Testing
- Breakfast skipping, Dinner skipping
- Where
- Germany
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Obesity, Morbid, Time Restricted Eating
Time-restricted Eating Among Pregnant Females With Severe Obesity
In the United States, a body mass index (BMI) of at least 35.0 kg/m2 affects about 15% of women of reproductive age. Severe obesity is a significant predictor of adverse perinatal outcomes including gestational diabetes mellitus…
- Conditions
- Obesity, Morbid, Time Restricted Eating, Pregnancy Weight Gain
- Trial name
- TRE-Preg (NCT06477120)
- Testing
- Time Restricted Eating
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Cardiometabolic Risk, Executive Function
Effects of Diet and Exercise Interventions on Cardiometabolic Risk Markers, Executive Function, and Intestinal Flora
The purpose of this study is to estimate the effects of diet and exercise interventions on body weight, cardiovascular metabolic markers, executive function, and intestinal flora among undergraduate students, as well as the…
- Conditions
- Cardiometabolic Risk, Executive Function, Intestinal Microbiome
- Trial name
- NCT04834687
- Testing
- Exercise, Diet
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Skipping Breakfast, Circadian Rhythms
Effect of Skipping Breakfast on Metabolic Function
The purpose of this study is to test the hypothesis that the disruption of the "normal" (three meals a day) eating pattern and prolonged overnight fasting caused by skipping breakfast: i) alters the expression of specific clock…
- Trial name
- NCT02093572
- Testing
- 3 standard meals/day, 2 meals/day (omit breakfast)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Healthy
Intermittent Fasting on Body Fat and Quality of Life
The purpose of this investigator-initiated study to check the feasibility that intermittent fasting has on body fat loss and quality of life.
- Trial name
- NCT06307275
- Testing
- Fasting, non fasting
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Obesity, Time Restricted Feeding
Time Restricted Feeding on Weight Loss and Cardio-protection (TREATY Trial)
Time restricted feeding (TRF) is a novel type of intermittent calorie restriction diet that involves eating a daily period of 8 hours or less.
- Conditions
- Obesity, Time Restricted Feeding, Weight Loss, Calorie Restriction
- Trial name
- TREATY (NCT03745612)
- Testing
- Time restricted feeding, Continuous Energy Restriction
- Where
- China
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Healthy, Impaired Glucose Tolerance
Effects of an Intermittent Fasting and Dietary Supplement Regimen on Glycemic Variability
The purpose of this study is to determine the short-term effect of a nutritional program consisting of a yerba mate supplement, fiber supplement, and intermittent fasting on glycemic variability in men and women with risk factors…
- Trial name
- NCT05493553
- Testing
- Dietary supplement regimen, Dietary supplement and intermittent fasting regimen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Unicity International, Inc.
Sports Injury, Intermittent Fasting
The Effect of Intermittent Fasting on Acute Subconcussive Head Impacts
The purpose of this study is to examine the effect of intermittent fasting on the acute neural responses to subconcussive head impacts.
- Trial name
- NCT05236127
- Testing
- Soccer Heading, Intermittent Fasting
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indiana University
Non-Alcoholic Fatty Liver Disease, Time Restricted Feeding
Effects of Time-restricted Eating Supported by Mobile Technology in Patients With Non-alcoholic Fatty Liver Disease: Randomized Controlled Trial
In non-alcoholic fatty liver disease (NAFLD), it is established that calorie restriction is the most essential dietary modification.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Time Restricted Feeding, Mobile Technology
- Trial name
- NCT05579158
- Testing
- Mobile application and wearable device, Time-restricted eating
- Where
- South Korea
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Intermittent Fasting, Obesity
Longitudinal Monitoring During Intermittent Fasting Protocols in Obese Adults
LIMITFOOD2 is a randomized clinical intervention study that investigates the effects of two different intermittent fasting protocols compared to a control group on the health of obese adults.
- Conditions
- Intermittent Fasting, Obesity, Time Restricted Eating
- Trial name
- LIMITFOOD2 (NCT06323889)
- Testing
- Modified Alternate Day Fasting, Time-Restricted Eating, Weight-loss counseling
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Zurich