Clinical trials: Intervention Effectiveness
Physical Activity, Sedentary Behaviour
Intervention to Improve 24-Hour Movement Behaviors in University Students
This study examined whether a personalized, WeChat-based behavioural intervention could help improve how university students allocate their time across daily movement behaviours, including physical activity, sedentary behaviour…
- Conditions
- Physical Activity, Sedentary Behaviour, Sleep
- Trial name
- NCT07393698
- Testing
- Personalized Online Behavioral Intervention
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- South China Normal University
Pleural Effusion
Comparing Active Versus Passive Aspiration in Therapeutic Thoracentesis: Efficacy, Procedure Time, and Patient Safety
This single-blind randomized controlled trial (RCT) aims to compare the efficacy and safety of active manual aspiration versus passive gravity drainage during therapeutic thoracentesis for large symptomatic pleural effusions.
- Trial name
- Thoracentesis (NCT07184736)
- Testing
- Active Manual Syringe Aspiration, Passive Gravity Drainage
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Physical Exercise
A Randomized Controlled Trial Using Stage-matched Intervention Based on the Transtheoretical Model of Change to Enhance Engaging in Regular Physical Exercise Among High School Female Students.
A randomized controlled trial that uses a Stage-matched intervention based on the Transtheoretical Model of Change to enhance engaging in regular physical exercise among high school female students.
- Trial name
- NCT05938634
- Testing
- Stage-matched interventions
- Where
- Iraq
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Clinical Practice Guidelines, Lower Limb Amputation Above Knee (Injury)
TeleEducation for Implementing a Clinical Practice Guideline For Amputees
The publication of a Clinical Practice Guideline (CPG) is often not enough for its correct use in the field of health care. There are barriers to the implementation of the CPG recommendations, including those related to the lack…
- Conditions
- Clinical Practice Guidelines, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Knee
- Trial name
- TEFICA (NCT05601349)
- Testing
- Telehealth-based strategy
- Where
- Colombia
- Volunteers
- 7 people
- Sponsor
- Grupo Rehabilitacion en Salud
Prevent Child Maltreatment
Family Networks Project Study One: An Efficacy Study of Stepping Stones Triple P for Children Under Age Two
The purpose of the project is to assess the initial efficacy of Stepping Stones Triple P-Positive Parenting Program (SSTP) with parents of children below age two with developmental disabilities to strengthen families and prevent…
- Trial name
- NCT01424943
- Testing
- Stepping Stones Triple P, BabyNet Services As usual
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of South Carolina
Affective Disorder
Effectiveness of a Cognitive Remediation Intervention Based on Virtual Reality for Promotion of Cognitive Functioning and Participation in Daily Life Among Persons With Affective Disorder
The purpose of this study is to test the efficacy of remedial cognitive intervention using The Functional Brain Trainer VR (FBT, Intendo ©) to improve cognitive functioning, participation in daily life occupations, and functional…
- Trial name
- NCT04288609
- Testing
- Intendu, Paper and Pencil cognitive remediation training
- Volunteers
- 40 people
- Sponsor
- Geha Mental Health Center
Hypertension, Diabetes Mellitus, Type 2
Implementation of a Comprehensive Intervention on Hypertension（HTN） and Type 2 Diabetes Mellitus（DM） at PHC Level
Background: The disease burden of hypertension(HTN) and type 2 diabetes mellitus(DM) is rising rapidly in China.Comprehensive interventions(Implementation strategies for providers and interventions for patients) are critical to…
- Trial name
- NCT05353699
- Testing
- Implementation strategies
- Where
- China
- Volunteers
- 12,648 people
- Sponsor
- National Center for Chronic and Noncommunicable Disease Control and Prevention, China CDC
Prediabetes, Hyperglycemia
Personalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With Prediabetes - Main Study
Sweetch is a personalized mobile-health platform coaching system (mobile phone app) designed to promote adherence to physical activity guidelines for people with prediabetes.
- Conditions
- Prediabetes, Hyperglycemia, Postprandial Hyperglycemia, Impaired Glucose Tolerance
- Trial name
- NCT03315663
- Testing
- Sweetch App & DBWS, Sweetch App Alone
- Where
- 2 sites in United States
- Sponsor
- Johns Hopkins University
Anxiety, Signs and Symptoms
Effectiveness of a Music Therapy Intervention in Cancer Patients Undergoing Active Treatment at the Jaén University Hospital: a Non-randomized Controlled Trial.
A cancer diagnosis and its clinical progression can cause patients physical, psychological, emotional, social, and spiritual distress.
- Conditions
- Anxiety, Signs and Symptoms, Oncologic Complications
- Trial name
- ECMONC (NCT07886658)
- Testing
- Music Therapy
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Jaén
Pain
Pharmacology and Non-pharmacology Approaches in Reducing Children's Pain and Fear During Painful Procedures
This study Will contribute in the knowledge of pediatric nurses during painful procedures such venipuncture
- Trial name
- NCT06326125
- Testing
- TICK-B, TKTX-Cream, TICK-B and TKTX-C
- Where
- Iraq
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Atrial Fibrillation
Effectiveness of Pulmonary Vein Isolation in Prevention of Atrial Fibrillation Following Heart Bypass Surgery
Atrial fibrillation (AF) is an irregular heart rhythm that occurs in 30% to 40% of patients following heart surgery. This irregular heart rhythm, although often self-limiting, can be cause for concern.
- Trial name
- NCT00338715
- Testing
- PVI with Medtronic's Cardioblate BP2 radiofrequency catheter
- Where
- Canada
- Volunteers
- 193 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Parkinson Disease
Can tDCS Enhance Efficacy of Rehabilitative Intervention for Freezing of Gait in Parkinson's Disease?
Freezing of gait in Parkinson's disease (PD) is a major cause of disability and falls and responds often incompletely to conventional therapy. The pathogenesis remains largely unknown and therapeutic alternatives are needed.
- Trial name
- NCT02205216
- Testing
- Active tDCS, Rehabilitation Therapy
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Tinnitus, Acute
In This Study, we Are Testing Whether Combining Two Interventions, in the Early Stages of Tinnitus, is More Effective in Quieting Tinnitus Than Using One Treatment Alone in the Later Stages of Tinnitus
Tinnitus affects one in seven adults long-term Once present persistently for 4 weeks, tinnitus does not usually disappear People generally become less aware of, and less affected by, their tinnitus over time Only one in six…
- Trial name
- ATtDCS (NCT07128004)
- Testing
- tDCS, sound therapy
- Volunteers
- 80 people
- Sponsor
- Newcastle University
HIV
Switching From Protease Inhibitor (PI) to Etravirine in HIV-1 Infected Subjects With Viremia Suppression
This is a 48 week randomized, prospective, controlled, open-label, proof-of-concept pilot clinical trial. Patients with HIV-1 infection on HAART PI-based regimen will be randomized to switch from the PI to etravirine (400 mg…
- Trial name
- NCT01034917
- Testing
- Etravirine 400 mg dissolved in water every 24 hours, Continue with the same antiretroviral regimen
- Where
- Spain
- Volunteers
- 43 people
- Sponsor
- Germans Trias i Pujol Hospital
Heart Failure
The Effect of Model-based Cardiac Rehabilitation on Self-care, Quality of Life, and Self-efficacy in Patients With Heart Failure
The main reason why heart failure (HF) is an important public health problem is that the incidence of HF is increasing and mortality rates remain unchanged despite the decline in the incidence of coronary artery disease.
- Trial name
- NCT06074887
- Testing
- transtheoretical model-based intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Cukurova University
Substance Use Disorders, Addiction, Alcohol
Evaluating the Effectiveness of Mobile Self-guided Psychological Interventions to Reduce Relapse in Substance Use Disorder
The aim of the study is to evaluate the effectiveness of mobile interventions in reducing craving and lapses in patients diagnosed with Substance Use Disorder.
- Conditions
- Substance Use Disorders, Addiction, Alcohol, Addiction, Substance
- Trial name
- NCT05730504
- Testing
- Mobile app-based self-guided interventions
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- PredictWatch
Cardiovascular Health, Physical Function
Preliminary Efficacy of a Technology-based Physical Activity Intervention for Older Korean Adults During the COVID-19 Pandemic
This study tested preliminary efficacy of a hybrid (web-based and center-based) PA intervention combining use of a smartwatch and mobile application.
- Trial name
- NCT05986058
- Testing
- Golden Circle
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- University of Illinois at Urbana-Champaign
Psychosis
Testing the Effectiveness of The Welcome Basket Intervention
The investigators propose to examine the effectiveness of a brief intervention that might better facilitate the transition into the community for people with schizophrenia or bipolar disorder with psychotic features.
- Trial name
- NCT02946255
- Testing
- Welcome Basket (WB), Welcome Basket Brief (WBbr), Treatment As Usual
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Centre for Addiction and Mental Health
Child Development, Maternal Depression
WASH Benefits Child Development Follow up
The purpose of this study is to determine if the effects of individual and combined water, sanitation, hygiene, and nutrition interventions in early childhood on child development and maternal mental health persist into middle…
- Trial name
- WASH-BFU (NCT04443855)
- Testing
- Water quality, Sanitation, Hand washing
- Where
- Bangladesh
- Volunteers
- 4,932 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Caregiver Subjective Burden, Depressive Symptoms
Effectiveness of an Online Training and Support Program (iSupport) for Informal Dementia Caregivers
Informal caregivers of people with dementia are at greater risk of developing physical and mental health problems when compared to the general population and to informal caregivers of people with other chronic diseases.
- Conditions
- Caregiver Subjective Burden, Depressive Symptoms, Anxiety Symptoms
- Trial name
- iSupportPT (NCT04104568)
- Testing
- iSupport for dementia - European-Portuguese version, e-book (comparator)
- Where
- Portugal
- Volunteers
- 184 people
- Sponsor
- Universidade do Porto
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