Clinical trials: Interventional；
Tobacco Use
Pilot Randomised Controlled Trial of ToQuit Intervention in India
Tobacco use is associated with high mortality, and a range of morbidities including cancer, and lung and cardiovascular diseases.
- Trial name
- ToQuit (NCT04782453)
- Testing
- ToQuit, a technology delivered tobacco cessation intervention, Tobacco quitting helplines
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sangath
Opioid Misuse and Addiction, Pain
Toward Zero Prescribed Opioids for Outpatient General Surgery
Investigators have created an opioid reduction "package" which includes patient education, non-narcotic pain control instructions, and limited (or no) opioid pain prescriptions provided at discharge in an attempt to reduce the…
- Trial name
- NCT05327777
- Testing
- Oxycodone, Zero Opioid Protocol
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Mental Illness Persistent, Chronic Disease
Reverse Colocated Integrated Care Intervention Among Persons With Severe Persistent Mental Illness at US-Mexico Border
This study evaluated whether patients with severe and persistent mental illness (SPMI) who received coordinated co-located behavioral health and primary care services were more likely to improve health outcomes after 12 months…
- Conditions
- Mental Illness Persistent, Chronic Disease, Hypertension, Diabetes
- Trial name
- NCT03881657
- Testing
- Reverse Colocated Integrated Care, Usual Care
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Health Resources in Action, Inc.
Healthy Nutrition, Diet, Healthy
Acute Effects of Dietary Medium-chain Fatty Acids on Lipid Profile
In the present study the plasma lipid profile was elucidated in healthy, lean males by the use of lipidomic analysis in the hours after an acute intake of medium-chain fatty acids (MCT) and long chain fatty acids (LCT)…
- Trial name
- Lipidomix (NCT06368271)
- Testing
- Lipidomics
- Where
- 2 sites in Denmark
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Diet Modification
Comparing Diet and Exercise Approaches in Women
The purpose of this study is to determine whether following a Curves high protein/low fat diet (30% carbohydrate, 45% protein, 25% fat) for 30-days several times during 16 weeks of participating in the Curves fitness program…
- Trial name
- CWW (NCT04372771)
- Testing
- Curves Circuit, Weight Watchers
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Posttraumatic Stress Symptoms
The Effect of Guided Narrative Technique on Child Post-traumatic Stress Symptoms Related to Teachers' Improper Criticism
Teachers' improper criticism may lead to posttraumatic stress symptoms (PTSS) in children. This cluster randomized controlled trial examined the effect of guided narrative technique (GNT) on child PTSS caused by teachers'…
- Trial name
- NCT05416671
- Testing
- guided narrative technique-writing
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Peking University
Functional Fitness
Development and Evaluation of the Healthy Beat Accupunch (HBA) Exercise Program for the Community Older Adults
The goals of this research project were: 1) to develop a senior-tailored Healthy Beat Accupunch (HBA) exercise program for community-dwelling older adults, 2) to test the effects of a six-month, instructor-led HBA exercise…
- Trial name
- HBA (NCT02567864)
- Testing
- Healthy Beat Accupunch exercise program, control
- Where
- Taiwan
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Sexual Violence
Pilot Study of the Ntombi Vimbela Sexual Violence Intervention Among Female Tertiary Students in South Africa
The pilot study aims to test the acceptability of content, feasibility of delivery methods and preliminary assessment of outcomes from the implementation of the Ntombi Vimbela intervention with volunteer groups of female first…
- Trial name
- NCT04607564
- Testing
- Ntombi Vimbela! intervention
- Where
- 6 sites in South Africa
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Medical Research Council, South Africa
Family Conflict, Marital Conflict
Families of Youth with Developmental Disabilities: a Theory-Based Intervention
This study is designed to evaluate a preventive intervention program designed to support families (parents and typically developing adolescent siblings) that include a child with an intellectual and/or developmental disability.
- Conditions
- Family Conflict, Marital Conflict, Communication
- Trial name
- NCT03495440
- Testing
- Center Sessions, At-home
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Chronic Kidney Diseases, Metabolic Syndrome
Theory-based Health Behaviour Change Intervention in Patients of Metabolic Syndrome With Chronic Kidney Disease
The pilot study will adopt a 2-arm, pretest-posttest, and assessor-blind randomized controlled trial design to examine the feasibility and acceptability of a theory-based health behaviour change intervention and examine its…
- Trial name
- NCT06527768
- Testing
- Theory-based health behaviour change interventio
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Exercise
Active Play Intervention for Preschoolers
The goal of this randomized clinical trial is to examine the effects of a planned movement in preschool-aged children. The main question is to determine What are the effects of a planned movement program on physical activity…
- Trial name
- Active Play (NCT05744791)
- Testing
- Active Play planned movement program
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Auburn University
Mental Health Issue
Mindfulness, Compassion and Self-compassion
Teachers in Hong Kong are susceptible to professional stress and its associated psychosomatic illnesses. To enhance teachers' well-being, mindfulness training is conducted in local schools.
- Trial name
- NCT05046691
- Testing
- 8-week mindfulness program
- Where
- Hong Kong
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cognitive Decline
ADL+2.0: Intervention for Prevention of Cognitive Decline in Community-dwelling Older Adults
Singapore's rising dementia incidence with an ageing population presents an urgent need for effective interventions that delay or prevent cognitive decline.
- Trial name
- ADL+ 2 (NCT07141160)
- Testing
- Combined: Mobile app + 6WELLS, Remote mobile based app
- Where
- Singapore
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Behavior, Eating
Menu to Meal (M2M) Menu Labeling Intervention Study
This study evaluates the impact of culturally tailored menu labeling interventions on psychosocial factors and ordering behavior among customers in two independently owned Hispanic restaurants in East-Central Texas.
- Trial name
- NCT07329452
- Testing
- Paper menu, Digital menu condition
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Smoking Cessation, Mental Illness
Mobile App for Smoking Cessation and Mental Health
Adults with serious mental illness (SMI) represent 5% of the United States population, yet account for 30% of all cigarettes smoked and are 2 to 3 times more likely to be dependent on nicotine compared with the general…
- Trial name
- NCT04887558
- Testing
- Smart-T Mental Health and NRT, Smart-T Mental Health+ and NRT, QuitGuide + NRT
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Healthy
A Study to Understand How the Study Medicine Called ARV-471 is Processed in Healthy Adults
The purpose of the study is to understand how the study medicine ARV-471 is processed in the body of healthy males and females who do not have the potential to have children.
- Trial name
- NCT05930925
- Testing
- [phenyl-14C]ARV-471, [oxoisoindolin-14C]ARV-471
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Frail Elderly Syndrome, Cognitive Impairment
Investigating My Active and Healthy Aging
This is a multicenter, multicultural, randomized control trial. Participants will be recruited from 10 centers located in Italy, Germany, Austria, Spain, United Kingdom, Belgium, Sweden, Japan, South Korea and Australia.
- Conditions
- Frail Elderly Syndrome, Cognitive Impairment, Physical Dependence
- Trial name
- my-AHA (NCT03342976)
- Testing
- My-AHA platform
- Where
- Italy
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Cardiovascular Diseases
Growing Healthy Hearts: A Pilot Randomized Control Trial to Test Gardening as an Intervention to Improve Health
The purpose of this study is to test the effect of group-based nutrition advice plus gardening (intervention) versus group-based nutrition advice alone on dietary intake of fruits and vegetables, physical activity, and lifetime…
- Trial name
- NCT04207268
- Testing
- Gardening and Nutrition Advice, Nutrition Advice
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Type 2 Diabetes, Quality of Life
Feasibility of Kanasina Gulabi, a Pilot Peer Support Intervention for Young Adults With Type 2 Diabetes in Mysore District, South India
The purpose of this study is to evaluate a pilot peer support intervention, entitled "Kanasina Gulabi" (Translation "My Dream Rose" in Kannada), designed to improve quality of life and diabetes management among young adults…
- Conditions
- Type 2 Diabetes, Quality of Life, Depression, Stigma, Social
- Trial name
- NCT06259318
- Testing
- Kanasina Gulabi
- Where
- India
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Duke University
Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter
Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers
This randomized clinical trial studies the Family Caregiver Palliative Care Intervention in supporting caregivers of patients with stage II-IV gastrointestinal, gynecologic, urologic and lung cancers.
- Conditions
- Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter, Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT01846520
- Testing
- educational intervention, telephone-based intervention, quality-of-life assessment
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
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