Clinical trials: Interventional
This Study Will Focus on In-office Dermatological Procedures
Split Face Study of the Duration of Local Anesthetics - Fifth Arm
This study will compare how long local anesthesia lasts when it is injected into different layers of the skin on the forearm. The investigators hypothesize that the numbing effect will last for different amounts of time depending…
- Trial name
- NCT07724418
- Testing
- Lidocaine HCl/Epinephrine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Endodontically Treated Teeth, Post Operative Pain
Effect of Intra-Canal Cryotherapy on Postoperative Pain After Endodontic Procedures
The goal of this randomised clinical trial is to evaluate the effect of cryotherapy on postoperative pain after primary and secondary root canal treatment.
- Trial name
- NCT06134713
- Testing
- cryotherapy with sterile saline at 2.5ºC, control with sterile saline at room temperature
- Where
- United Arab Emirates
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ajman University
Sleep
A Theory-based Sleep Intervention in Improving Sleep Quality in Adolescents
Sleep education has been used as a method of primary and secondary prevention of sleep problems in all age groups. An especially vulnerable age group are adolescents who frequently have poor sleep habits and suffer from sleep…
- Trial name
- NCT02551913
- Testing
- Control, Intervention
- Where
- Iran
- Volunteers
- 2,841 people, healthy volunteers welcome
- Sponsor
- Qazvin University Of Medical Sciences
Healthy Adults.
Investigating the Acute Effects of Flavonoids in Blueberries on Cognitive Function.
This study was a controlled, cross-over, acute flavonoid intervention trial with younger and older adults. Subjects consumed a blueberry beverage during one visit and a control beverage on another.
- Trial name
- NCT01289860
- Testing
- Flavonoids, Control
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Reading
Dementia, Alzheimer Disease
Translating a Dementia Caregiver Intervention Into a Mobile Application
The overall goal of this development project is to combine elements of two efficacious interventions into a mobile health (mHealth) App for informal dementia caregivers.
- Conditions
- Dementia, Alzheimer Disease, Caregiver Burnout
- Trial name
- NCT04330482
- Testing
- CARE-Well App, Internet Links
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Health, Subjective, Work Related Stress
Evaluation of the CHIME Intervention for Improving Early Head Start/Head Start Educator Well-being
This study will test how well a mindfulness-based intervention called CHIME improves the emotional well-being of educators in Early Head Start and Head Start (EHS/HS) settings.
- Conditions
- Health, Subjective, Work Related Stress, Compassion, Social Skills
- Trial name
- CHIME (NCT05791825)
- Testing
- Cultivating Healthy Intentional Mindful Educators
- Where
- United States
- Volunteers
- 571 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Primary Prevention
FIT FIRST Teen - School Intervention Study
The goal of this cluster randomised controlled trial is to investigate the effects of the FIT FIRST Teen program on adolescents' physical fitness, motivation, and well-being, as well as the implementation of such a program within…
- Trial name
- NCT06615791
- Testing
- FIT FIRST Teen
- Where
- Denmark
- Volunteers
- 912 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Healthy Aging
An Aging Healthy Intervention for Older Adults Delivered by Community Health Workers in Senior Centers: A Clinical Trial
The aCT Study will develop, implement and evaluate a community health worker (CHW) integrated model of care delivery for older adults that is senior center based.
- Trial name
- aCT (NCT07428174)
- Testing
- aCT CHW intervention
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- George Mason University
HIV Prevention
Scalable Interventions to Increase PrEP Adherence: Value Affirmation and Future Selves
Pre-exposure prophylaxis, or PrEP, is a relatively new HIV prevention method where individuals who are at risk for HIV but do not currently have it take a daily pill (Truvada).
- Trial name
- SIIPA (NCT03278990)
- Testing
- Value Affirmation and Future Selves Combination, Control writing exercise
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Stuart Fisk
Older People
Impact of a Musical Intervention in Older Adults (ARA Project - Armonía Recreativa Para El Adulto Mayor)
Currently, the world is facing the challenge of population aging. At this stage of life, various deteriorations, such as cognitive decline, begin to appear, significantly impairing the quality of life.
- Trial name
- ARA (NCT06787820)
- Testing
- Music intervention
- Where
- Chile
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Diego Portales
Lung Cancer, Nonsmall Cell, COPD
Breathe Easier II: A Dyad-based Multiple Behavior Intervention
This pilot randomized control trial (RCT) will test a 12-week, multiple behavior intervention physical activity and stress management for survivors with early stage lung cancer (stages I-III) and their family members (1 survivor…
- Conditions
- Lung Cancer, Nonsmall Cell, COPD, Self-Management, Physical Inactivity
- Trial name
- BE (NCT05956782)
- Testing
- Breathe Easier
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Cognitive Aging
Intervention Comparative Effectiveness for Adult Cognitive Training
The study will compare the effect of broad and directed (narrow) technology-based training on basic perceptual and cognitive abilities in older adults and on the performance of simulated tasks of daily living including driving…
- Trial name
- ICE-ACT (NCT03141281)
- Testing
- BrainHQ, Rise of Nations, IADL Training
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Florida State University
Urinary Tract Infection, Kidney Diseases
A Randomized Control Trial Comparing Single vs. Multiple Application of Lidocaine Analgesia Prior to Urethral Catheterization Procedures
The purpose of this study is to determine if a single application of Lidocaine gel topical anesthesia is as effective in decreasing the discomfort associated with urinary catheterization as two applications, within our pediatric…
- Conditions
- Urinary Tract Infection, Kidney Diseases, Ureteral Diseases, Ureteral Obstruction
- Trial name
- NCT00142064
- Testing
- observed levels of pain
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Elective Procedures Requiring Mechanical Ventilation
Evaluation of Novel Cardio-Pulmonary Physiological Monitor, the VQm PHM™, for Acute Care Medicine
This is a prospective, observational study to assess agreement of pulmonary health parameters measured by a new non-invasive physiologic monitor, the VQm pulmonary health monitor (PHM)™ with clinical gold standards.
- Trial name
- NCT04730063
- Testing
- VQm PHM™
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rostrum Medical Innovations Inc.
Nasal Obstruction
The Vivaer Procedure for Treatment of the Septal Swell Bodies (SWELL)
Post-market study to access the clinical use of the Vivaer Arc Stylus to treat Septal Swell Bodies (SSB).
- Trial name
- SWELL (NCT05099263)
- Testing
- Vivaer Arc Stylus
- Where
- 9 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aerin Medical
Low Back Pain, Neck Pain
ENBORTH-TR Intervention for Back/Neck Pain
This study was conducted to investigate the effectiveness of the ENBORTH-TR training programme given in addition to client-centred intervention in individuals with low back and/or neck pain.
- Trial name
- NCT06916533
- Testing
- ENBORTH-TR Intervention, Client-centred Occupational Therapy Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
The Focus is the Prevention and Promotion of Mental Well-being and is a Universal Delivery Intervention
Promotion of Mental Health in Adolescents: A School-Based Preventive Version of the Unified Protocol (UP-A Kind)
The goal of this clinical trial is to assess the efficacy of the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders for Adolescents (UP-A; Ehrenreich-May et al., 2018) as a universal school-based preventive…
- Trial name
- UP-A Kind (NCT07021001)
- Testing
- UP-A, a cognitive-behavioral structured group intervention, was adapted as a universal preventive intervention to be delivered in school settings (UP-A Kind).
- Where
- Portugal
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Influenza
A Study of Exclusion Criteria in a University Population
Much of community transmission of seasonal and pandemic influenza occurs in younger individuals, because of their susceptibility and their social interaction patterns.Universities are places where transmission of influenza is…
- Trial name
- eX-FLU (NCT01472536)
- Testing
- Sequestration
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pain During and After Endovenous Laser Obliteration of Large Saphenous Vein Based on Lidocaine Tumescent Concentration
Efficacy of Variable Lidocaine Concentrations in Tumescent Anesthesia for Pain Control During and After Endovenous Laser Procedure; Non-inferiority Trial
Endovenous laser treatment is a minimally invasive procedure that has been shown to be a safe and effective treatment for varicose veins.
- Trial name
- NCT02192411
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Midwest Vein Center
Periodontitis, Attachment Loss, Periodontal
The Use of a Non-Incised Minimally Invasive Flap Procedure in Conjunction With Emdogain® MI Compared to Traditional SRCP
This study is designed to evaluate the use of Emdogain® MI in a procedure where a significant portion of the lining of the sulcus is removed by curettage (similar to the traditional clinical procedure described as "gingival…
- Trial name
- NCT05964699
- Testing
- Minimally invasive periodontal therapy with use of Emdogain, Minimally invasive periodontal therapy without the use of Emdogain
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
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