Clinical trials: Interventions
Obesity
Plant-based Protein-rich Weight Loss Intervention in 55+ Adults With Obesity
The objective of the 2EAT RCT is to investigate whether a shift towards more plant-based (≥60% with a minimum of 50%) protein intake can be achieved in an energy restricted diet for three and six months in older adults (55+) with…
- Trial name
- 2EAT (NCT07429136)
- Testing
- More plant-based protein intake during weight loss
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Amsterdam University of Applied Sciences
Autism Spectrum Disorder, Autism
Halliwick Hydrotherapy and Snoezelen
The aim of this study was to evaluate the effectiveness of the Halliwick concept in the adapted Snoezelen multi-sensory environment, in the gross mobility of children belonging to the autism spectrum.
- Conditions
- Autism Spectrum Disorder, Autism, Sensory Disorder
- Trial name
- NCT05134844
- Testing
- Hydrotherapy- Snoezelen, Snoezelen
- Where
- Greece
- Volunteers
- 53 people
- Sponsor
- University of Thessaly
Physical Activity, Childhood Obesity
The LEADS Trial (Linking Exericise for Advancing Daily Stress Management)
Chronic stressors have wide-reaching harmful effects on the physical, social, and psychological well-being of many African American (AA) families.
- Trial name
- LEADS (NCT07176234)
- Testing
- Treatment, Health Education
- Where
- 2 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Social Isolation in Older Adults, Loneliness
Community-Based Social Connection Intervention Program to Improve Cardiovascular and Brain Health
This study evaluates the effectiveness of a community-based social connection intervention program (SCIP) designed to reduce social isolation and loneliness and improve cardiovascular and brain health among older adults living in…
- Conditions
- Social Isolation in Older Adults, Loneliness, Stroke, Cognitive Decline
- Trial name
- NCT07319663
- Testing
- Social Connection Intervention Program (SCIP): Community activities, peer-support groups, and home-based coaching to reduce social isolation and loneliness.
- Where
- Ecuador
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Early Life Adversity, Chronic Stress
Health Experiences & Early Life Disadvantages
Growing up in a low-income household has been shown to increase risk for, and susceptibility to many illnesses.The purpose of the study is to test an affective intervention for reversing biological risk factors, as related to…
- Trial name
- HEELD (NCT02400593)
- Testing
- Meditation Workshop
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
COVID-19 Vaccination
HOPE Intervention for COVID-19
The Harnessing Online Peer Education COVID-19 (HOPE COVID-19) intervention will assess whether a peer-led online support community can improve behavioral health outcomes related to COVID-19.
- Trial name
- NCT04376515
- Testing
- HOPE intervention
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Breastfeeding, Intention
Prenatal Interventions to Promote Exclusive Breastfeeding
Background: Exclusive breastfeeding through age 6 months is the optimal infant feeding method due to lifesaving benefits for children and mothers (AAP, others).
- Conditions
- Breastfeeding, Intention, Health Behavior
- Trial name
- NCT03107715
- Testing
- Breastfeeding Champion, Positive Messaging
- Where
- United States
- Volunteers
- 243 people
- Sponsor
- Lydia Furman
Prostate Cancer
Decision Support Interventions (DESI) for Prostate Cancer Screening and Treatment - Study 2
Researchers in this study will determine whether providing decision support interventions (DESIs) to men with low risk prostate cancer improves their decision-specific knowledge and alters their treatment decisions.
- Trial name
- NCT01244568
- Testing
- Prostate cancer treatment DESI
- Where
- 2 sites in United States
- Volunteers
- 218 people
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Psychological Distress
German Evaluation of the Effectiveness of the Psychological Intervention Managing Cancer and Living Meaningfully (CALM)
Purpose of this randomized controlled trial is to test the efficacy of the individual psychotherapeutic intervention Managing Cancer and Living Meaningfully (CALM) in a German sample of patients with advanced cancer.
- Trial name
- NCT02051660
- Testing
- Manualized CALM intervention, Non-manualized supportive intervention.
- Where
- 2 sites in Germany
- Volunteers
- 206 people
- Sponsor
- University of Leipzig
Melanoma Stage Iv, Metastatic Melanoma
Metastatic Melanoma Patients on Immunotherapy With Nutritive Intervention Based on Mediterranean Diet
This research will study the effect of Mediterranean diet intervention in patients undergoing immunotherapy treatment for metastatic melanoma and its relationship with gut microbiome and quality of life.
- Trial name
- MINI-MD (NCT06236360)
- Testing
- Mediterranean Diet Intervention
- Where
- Croatia
- Volunteers
- 30 people
- Sponsor
- University Hospital Rijeka
Smoking Cessation, Motivation
Mating-EFT Smoking Cessation Intervention
The current proposal aims to develop and establish the effectiveness of a novel behavioral smoking cessation intervention. Previous research has shown that having smokers engage in episodic future thinking (EFT) about specific…
- Trial name
- NCT03431324
- Testing
- Episodic Future Thinking about Mating Opportunities, Targeted Mating-EFT Intervention
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Respiratory Tract Infections, Pneumonia
Randomised Exposure Study of Pollution Indoors and Respiratory Effects
The purpose of this study was to determine whether reduced exposure to indoor air pollution would reduce ALRI incidence in children <18 months of age.
- Trial name
- RESPIRE (NCT01047696)
- Testing
- Plancha
- Where
- Guatemala
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Parkinson Disease
Changes in Functional Performance in Individuals With Parkinson's Disease Following 2-month Physiotherapy Intervention
Aim of current study was to evaluate the effect of a 2-month comprehensive physiotherapy intervention on different aspects of functional performance.
- Trial name
- NCT03568903
- Testing
- Comprehensive physical therapy
- Volunteers
- 44 people
- Sponsor
- University of Tartu
Bleeding
Novel Approaches in Preventing and Limiting Events III Trial (NAPLES III): Bivalirudin in High-risk Bleeding Patients
Bleeding occurring during percutaneous coronary interventions (PCI has now emerged as one of the most common complication of PCI and adversely affect in-hospital, short- and long-term outcome.As bivalirudin proved its…
- Trial name
- NAPLESIII (NCT01465503)
- Testing
- Bivalirudin, Unfractionated Heparin
- Where
- 2 sites in Italy
- Volunteers
- 837 people
- Sponsor
- Clinica Mediterranea
Cardiac Surgery
Non-pharmacologial, Non-invassive Intervention Before Cardiac Surgery: a Randomized Controlled Trial
Perioperative neurological complications in cardiovascular surgical procedures are associated with a significant risk of mortality and disability.
- Trial name
- NICE (NCT06791551)
- Testing
- active RIPC and tDCS
- Where
- China
- Volunteers
- 200 people
- Sponsor
- China National Center for Cardiovascular Diseases
Breast Cancer Female
Breaking Through the Brain Fog: An Online Research Study
This study will investigate the benefits of distinct brain health trainings in breast cancer survivors (age 30-80) with cognitive concerns post-chemotherapy. This study can be completed from the comfort of participant's own home.
- Trial name
- NCT05444231
- Testing
- Brain Training A, Brain Training B, Brain Training C
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- The University of Texas at Dallas
Foreign Body Airway Obstruction
Prospective Evaluation of Foreign Body Airway Obstruction Interventions Among Adults and Children
Foreign body airway obstruction (FBAO, choking) is a life-threatening emergency requiring time-sensitive treatment to prevent severe injury or deaths.
- Trial name
- NCT07365137
- Testing
- Abdominal thrust, Back blows, Chest compressions/thrusts
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- University of Calgary
Exercise Training
Plyometric Exercise to Improve Rapid Force Production in Older Men
Rapid force production declines as a consequence of ageing. Given the functional relevance of rapid force production, exercise interventions in older adults should aim at improving the capacity to produce force rapidly.
- Trial name
- NCT03645772
- Testing
- Exercise intervention
- Where
- Belgium
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Overweight, Obesity
New DIETs: New Dietary Interventions Enhancing the Treatment for Weight Loss
Several studies have shown differences in health-related outcomes by dietary pattern. These patterns have included those participants following vegan (no meat, poultry, fish, dairy, or eggs), vegetarian (no meat, poultry, or…
- Trial name
- New DIETs (NCT01742572)
- Testing
- Diet
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Dietary Intervention, Pre Diabetes
Acceptability, Feasibility and Effectiveness of a Worksite Intervention to Lower Cardiometabolic Risk in South Africa
As an important way to translate cardiovascular disease prevention efforts, worksite interventions can facilitate healthy food choices, health education, and social support.
- Conditions
- Dietary Intervention, Pre Diabetes, Hypertension
- Trial name
- NCT04494139
- Testing
- Behavioral and Canteen intervention, Canteen
- Volunteers
- 350 people
- Sponsor
- Durban University of Technology
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