Clinical trials: Interventions
Cardiovascular Diseases
Web-based Physical Activity Intervention to Promote Physical Activity
In this study insufficiently active adults with obesity will be assigned to either the Physical Activity for The Heart (PATH) intervention or an attention control group.
- Trial name
- NCT05803304
- Testing
- PATH Intervention, Attention Control Intervention, Physical activity tracker
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Emory University
Overweight, Obesity
Toddler Overweight Prevention Study Among Low-Income Families
The hypothesis is that toddlers with parents who are randomized to a parenting intervention and toddlers with parents who are randomized to the maternal intervention focused on maternal diet and physical activity will be more…
- Conditions
- Overweight, Obesity, Depression
- Trial name
- TOPS (NCT02615158)
- Testing
- Maternal Physical Activity and Nutrition, Parenting, Child Safety
- Where
- 2 sites in United States
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
HIV, AIDS
Adherence Support Intervention for Persons Living With HIV/AIDS (PLWHA) on Antiretroviral Therapy (ART) in Estonia
The specific aim of the study is to assess antiretroviral therapy adherence and evaluate the impact of a situated treatment adherence intervention program among persons living with HIV/AIDS on antiretroviral therapy in Estonia.
- Conditions
- HIV, AIDS, Medication Adherence
- Trial name
- NCT01789138
- Testing
- Situated Optimal Adherence Intervention
- Where
- 2 sites in Estonia
- Volunteers
- 519 people
- Sponsor
- University of Tartu
Cardiovascular Risk Factor
South Asian Healthy Lifestyle Initiative (SAHELI)
Research show that South Asians (SA) have a high burden of Cardiovascular Disease (CVD) risk factors of which, poor diet and physical inactivity remain the major lifestyle risk factors in SA.
- Trial name
- SAHELI (NCT03336255)
- Testing
- South Asian Healthy Lifestyle Initiative (SAHELI)
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Prospective, Single-blind
Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children.
In high-income societies the use of health care and medication is steadily increasing. Children have high morbidity, many visits at the general practitioner, an increasing number of hospitalisations, and an increasing use of…
- Conditions
- Prospective, Single-blind, Clinical, Trial
- Trial name
- NCT01694108
- Testing
- BCG-vaccine (SSI)
- Where
- 3 sites in Denmark
- Volunteers
- 4,262 people
- Sponsor
- Lone Graff Stensballe
Alcohol Consumption
Pilot Study of a Computer-Based Intervention for Alcohol Misuse in the Emergency Department
Alcohol misuse amongst youth is a significant clinical and public health problem. The Emergency Department (ED) is an important setting for the treatment of alcohol-related problems as it is often the first point of contact…
- Trial name
- NCT01146665
- Testing
- Computer-based PAF
- Where
- 3 sites in Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Cocaine Dependence
A Sequenced Behavioral and Medication Intervention for Cocaine Dependence
This study will investigate a treatment strategy in which a computer-assisted behavioral intervention will be used to help individuals stop their use of cocaine.
- Trial name
- NCT01986075
- Testing
- Computer-assisted behavior therapy, Mixed-Amphetamine Salts- Extended Release (MAS-ER)
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- New York State Psychiatric Institute
HIV Infections
A Peer-Driven Intervention to Increase PrEP Uptake Among Minority MSM
The objective of this study is to develop an effective peer-driven intervention (PDI) approach and assess its feasibility and efficacy on pre-exposure prophylaxis (PrEP) uptake among men who have sex with men.
- Trial name
- NCT05161663
- Testing
- Peer-driven intervention
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Sedentary Behavior
A Culturally Adapted, Social Support-Based, Physical Activity Interventions for South Asian Indian Women in the United States
The purpose of this study is to assess the feasibility and acceptability of a peer-based dyadic social support health coaching physical activity (PA) intervention in inactive South Asian Indian (SAI) and to explore preliminary…
- Trial name
- NCT05966506
- Testing
- Dyad-based Zoom health coaching, Fitbit activity monitor, Electronic newsletters
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Aged, Experiential Learning
Community Beauty and Health Program for Older Adults: An Experiential Learning Trial
This study develops and evaluates a "Senior Beauty and Health Care" course designed to improve students' awareness, attitudes, and skills in caring for older adults' appearance and well-being.
- Conditions
- Aged, Experiential Learning, Health Education
- Trial name
- NCT07053592
- Testing
- Geriatric Ｂeauty and Ｈealth Care Learning Program
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Burns, Pediatric ALL
Telemedicine Optimized Burn Intervention
Because burn patients and their caregivers often live long distances from regional burn centers, access to expert burn care is limited, resulting in a negative effect on adherence to treatment and a higher risk of wound…
- Trial name
- TOBI (NCT05019144)
- Testing
- Face-to-face burn care, Telemedicine enhanced burn care
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Medical University of South Carolina
Acute Coronary Syndrome (ACS)
PROSPECT II & PROSPECT ABSORB - an Integrated Natural History Study and Randomized Trial.
The present study has two components, an overall prospective observational study using multimodality imaging (PROSPECT II) that will examine the natural history of patients with unstable atherosclerotic coronary artery disease…
- Trial name
- P2 (NCT02171065)
- Testing
- ABSORB BVS
- Where
- Sweden
- Volunteers
- 902 people
- Sponsor
- Uppsala University
Major Depressive Disorder
The Effects of Videogames on Depression Symptoms and Brain Dynamics
The purpose of the study is to evaluate the effects of a game-based digital-therapeutics (DTx) medical software device on the symptoms of depression in adults with confirmed major depressive disorder.
- Trial name
- NCT05426265
- Testing
- MEL-T01, MEL-S01
- Where
- 6 sites in Finland
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- Aalto University
Angina
Effectiveness of Ranolazine on Reducing Chest Pain in Patients With Blockage But no Stents
To determine if ranolazine improves angina symptoms at 4 months compared with placebo among patients who are deferred for receiving a Percutaneous Coronary Intervention (PCI) based on the Fractional Flow Reserve (FFR) measurement.
- Trial name
- IMWELL3 (NCT02147834)
- Testing
- Ranolazine, Sugar pill
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- North Florida Foundation for Research and Education
Diabetes Mellitus, Type 2, Substance-related Disorders
Screening, Brief Intervention, and Referral to Treatment in Primary Care
This add-on study of providing tobacco, alcohol and other drug screening, brief intervention and referral for treatment to a primary care high risk diabetic population leverages the existing research resources of a funded parent…
- Trial name
- SBIRT-PC (NCT01966432)
- Testing
- Referral to Treatment, Brief Intervention
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Duke University
Vaccine Refusal, Covid19
Project 2VIDA! COVID-19 Vaccine Intervention Delivery for Adults in Southern California
The United States (U.S.) is the country with the largest number of infections and deaths due to COVID- 19 and racial/ethnic minorities are disproportionately affected.
- Trial name
- 2VIDA! (NCT05022472)
- Testing
- COVID-19 Individual Awareness and Education., COVID-19 Community Outreach & Health Promotion., COVID-19 Individual Health Education & Linkages to Medical and Supportive Services.
- Where
- 6 sites in United States
- Volunteers
- 1,051 people, healthy volunteers welcome
- Sponsor
- Britt Skaathun
Weight Loss, Pre Diabetes
Healthy Body Healthy Souls in the Marshallese Population
The primary aim is to pilot test a weight-loss intervention for Marshallese adults, referred to throughout as Healthy Bodies Healthy Souls (HBHS).
- Conditions
- Weight Loss, Pre Diabetes, Overweight and Obesity
- Trial name
- NCT03377244
- Testing
- HBHS, HBHS Policy, WORD DPP
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Bariatric Surgery
Gaining Optimism After Weight Loss Surgery (GOALS) II
This randomized controlled trial examines the feasibility, acceptability, and preliminary impact of an adapted positive psychology-motivational interviewing (PP-MI) intervention for physical activity among patients who have…
- Trial name
- GOALS (NCT04868032)
- Testing
- Positive Psychology-Motivational Interviewing, Physical Activity Education Control
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Massachusetts General Hospital
Suicide
Suicide Prevention Intervention for At-Risk Individuals in Transition
The four year SPIRIT Trial, or Suicide Prevention Intervention for at-Risk Individuals in Transition, will recruit 800 pretrial jail detainees at risk for suicide.
- Trial name
- SPIRIT (NCT02759172)
- Testing
- Safety Planning Intervention
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- Michigan State University
Breast Cancer, Pregnancy Related
Hair Care Product Use Among Women Of Color
The purpose of this study is to reduce use of personal care products that contain endocrine disrupting chemicals among women. For this pilot intervention, the investigators focus on the hair care product class of personal care…
- Conditions
- Breast Cancer, Pregnancy Related, Exposure During Pregnancy
- Trial name
- NCT04493892
- Testing
- Educational Intervention
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Columbia University
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