Clinical trials: Intrathecal Morphine
Opioid-Related Disorders
Intrathecal Morphine for Robotic-assisted Laparoscopic Hysterectomy.
Is there any difference in the intensity of postoperative pain, nausea, urinary retention and legth of hospital stay in patients undergoing robotic assisted laparoscopic surgery if they receive intrathecal morphine or peroral and…
- Trial name
- NCT04675840
- Testing
- Robotic-assisted hysterectomy
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karlstad Central Hospital
Cesarean Section Complications
Comparison of the Erector Spinae Plane Block Versus Intrathecal Morphine on Post-Cesarean Delivery Analgesia
This study is a Randomized Control Trial comparing the Erector Spinae Plane Block with intrathecal morphine for post cesarean delivery analgesia.
- Trial name
- ESPCS (NCT04256642)
- Testing
- Erector Spinae Plane Block, Intrathecal morphine
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Intrathecal Morphine, Caesarean Section
Intravenous Nalbuphine for Prevention of Intrathecal Morphine-induced Nausea and Vomiting in Patients Undergoing Cesarean Section: A Double-blind, Randomized Controlled Trial.
We study efficacy of iv nalbuphine in prevention of intrathecal morphine-induced nausea and vomiting in patients undergoing cesarean section.
- Conditions
- Intrathecal Morphine, Caesarean Section, Postoperative Nausea and Vomiting, Neuraxial Opioid
- Trial name
- NCT06837129
- Testing
- A single dose of 4 mg iv nalbuphine
- Where
- 2 sites in Thailand
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Post Operative Nausea and Vomiting
Aromatherapy for Prevention of Intrathecal Morphine Induced Nausea and Vomiting
This study evaluates the effect of combining non pharmacological anti emetic prophylaxis, namely peppermint essential oil to granisetron and dexamethasone in patient who receive intrathecal morphine for lower segment cesarean…
- Trial name
- NCT03434340
- Testing
- Peppermint essential oil, Granisetron, Dexamethasone
- Where
- Malaysia
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Postoperative Pain
Quadratus Lumborum Block vs Intrathecal Morphine for Post-Cesarean Analgesia
İn this study, planned to compare the post-operative analgesic efficacy of Intrathecal Morphine Administration and anterior Quadratus lumborum Block in elective cesarean section operations.
- Trial name
- NCT06612424
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK, İNTRATECHAL MORPHİNE GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Cesarean Section, Spinal Anesthesia
Comparison of Three Different Doses of Intrathecal Morphine for Analgesia After Cesarean Section
In our study, It was aimed to determine the dose of morphine that provides the most effective analgesia with the least incidence of side effects in the postoperative period.
- Conditions
- Cesarean Section, Spinal Anesthesia, Postoperative Analgesia
- Trial name
- NCT05317572
- Testing
- 80 mcg intrathecal morphine, 120 mcg intrathecal morphine, 160 mcg intrathecal morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Pruritus
Effect of Granisetron on Morphine Induced Pruritus in Cesarean Section
Neuraxial anesthesia, which includes epidural anesthesia and intrathecal anesthesia, is a frequent anesthetic approach for caesarean delivery and other lower abdominal and lower limb anesthetic procedures.
- Trial name
- NCT03483870
- Testing
- Morphine Sulfate, Granisetron
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cesarean Delivery
Intravenous Methadone Versus Intrathecal Morphine for Analgesia Following Cesarean Delivery
The purpose of this study is to determine if there is a difference in opioid requirements at 0-48 hours after scheduled cesarean delivery in patients receiving 150 mcg intrathecal morphine compared to 0.2 mg/kg (maximum 20 mg)…
- Trial name
- NCT06826742
- Testing
- Intravenous line (IV) Methadone, Intrathecal Morphine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Perineal Surgery
Intrathecal Atropine Versus Intravenous Ondasetron in Post Operative Nausea Due to Intrathecal Morphine
To compare between intrathecal atropine versus preoperative administration of IV ondansetron in decreasing incidence of post operative nausea and vomiting related to intrathecal opioids in post operative period in perineal…
- Trial name
- NCT05137288
- Testing
- Ondansetron , atropine and bupivacaine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Post-operative Pain
The Pectoralis (PECS2) Block Versus Intrathecal Morphine
50 patients with American Society of Anesthesiologists (ASA) grade I to II, 18 to 60 years of age scheduled for Modified Radical Mastectomy surgery, Will be included in the study.
- Trial name
- NCT06016205
- Testing
- intrathecal morphine injection, ultrasound guided PECS2 block
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Analgesia Obstetrical, Analgesia
Intrathecal Versus Epidural Morphine for Post-Cesarean Analgesia
Cesarean section is one of the most commonly performed surgical procedures worldwide, making effective management of acute postoperative pain a key issue in obstetric anesthesiology.
- Conditions
- Analgesia Obstetrical, Analgesia, Post Operative Pain, Patient Satisfaction
- Trial name
- NCT07386353
- Testing
- Intrathecal Morphine, Epidural Morphine
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital Central do Funchal
Postoperative Pain
Abdominal Wall Local Anesthesia to Maximize Postoperative Pain Control After Cesarean Delivery
This study has been designed to determine if women undergoing cesarean delivery with spinal anesthesia and routine pain management who also have an additional ultrasound guided transversus abdominis plane (TAP)block using…
- Trial name
- NCT01261637
- Testing
- Ropivicaine
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Postoperative Analgesia
Quadratus Lumborum in Cesarean Section Trial
Postoperative pain of a caesarean section may be of high intensity, especially in the first 48 hours after the procedure, which affects the mother / newborn relationship, in addition to having the potential to progress to chronic…
- Trial name
- QUALICS (NCT03673280)
- Testing
- Quadratus Lumborum Block
- Where
- Brazil
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Pruritus Caused by Drug
Propofol for Prophylaxis of Morphine Induced Pruritis in Caesarean Section
the goal of this randomized clinical trial is to find the optimum sub hypnotic dose of iv propofol that prevents the incidence of itching induced from intrathecal morphine used in spinal anesthesia in caesarean section operation.
- Trial name
- NCT06188546
- Testing
- Propofol
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postdural Puncture Headache, Post-Lumbar Puncture Headache
Incidence of Headache Following an Unintentional Dural Puncture
The purpose of this study is to evaluate the use of intrathecal morphine administration following an unintentional dural puncture, to decrease the incidence of post dural puncture headaches (PDPH) in obstetric patients.
- Conditions
- Postdural Puncture Headache, Post-Lumbar Puncture Headache, Cerebrospinal Fluid Leaks
- Trial name
- NCT01977898
- Testing
- Morphine, Saline
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Quality of Recovery, Anesthesia
Improving ObsQoR-11 With Continuous Wound Infusion Versus Intrathecal Morphine After Elective Cesarean Delivery
The purpose of this prospective randomized double-blinded and controlled study is to evaluate the quality of recovery after elective cesarean delivery using the Obstetric Quality-of-Recovery-11 (ObsQoR-11) score at 24 hours…
- Conditions
- Quality of Recovery, Anesthesia, Postoperative Pain, Cesarean Section
- Trial name
- CIVIMEC (NCT05696678)
- Testing
- Intrathecal Morphine, Ropivacaine 0.2%
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Gynecological Cancer Surgery, Regional Anesthesia Morbidity
The Effect of Analgesia Methods Applied in Gynecological Cancer Surgeries on Postoperative Analgesia
The aim of this study is to compare the effectiveness of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia in gynecological cancer surgeries.
- Trial name
- NCT06382376
- Testing
- Intrathecal morphine administered group, Four quadrant transversus abdominis plane block applied group
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Cesarean Section, Intrathecal Morphine
The Contribution of Intrathecal Morphine Administration to Postoperative Patient Satisfaction During Cesarean Delivery
Evaluating the contribution of intrathecal morphine administration to postoperative patient satisfaction during cesarean delivery with the QoR-40 (Quality of Recovery 40) patient satisfaction compilation quality scale, scored…
- Conditions
- Cesarean Section, Intrathecal Morphine, Quality of Recovery 40
- Trial name
- ITM (NCT06076018)
- Testing
- Group morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Labor Pain
CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens
Analgesia in labour is not readily available in many parts of Sub-Saharan Africa. The overall cost of Epidural services in terms of human personnel and financial implication makes this inaccessible to many women in labour.
- Trial name
- SSS (NCT03117595)
- Testing
- Bupivacaine-fentanyl, Bupivacaine-fentanyl morphine
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Beckley
Analgesic Drug Dependence, Sensory Disorders
Intrathecal Morphine Microdose Method Sensory Changes
Following the retrospective study on the effectiveness of the microdose method of intrathecal morphine therapy, the investigators are interested in measuring the sensory changes at 4 time points during the microdose method.
- Conditions
- Analgesic Drug Dependence, Sensory Disorders, Chronic Pain
- Trial name
- NCT03395275
- Testing
- Quantitative Sensory Tests, surveys
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston