Clinical trials: Invasive Ventilation
Chronic Obstructive Pulmonary Disease
Effects of Non-invasive Ventilation on Rehabilitation Outcome in COPD-patients
The aim of the study is to find out if nocturnal non-invasive ventilation during pulmonary rehabilitation increases exercise capacity and quality of life more than pulmonary rehabilitation alone.
- Trial name
- NCT01384981
- Testing
- pulmonary rehabilitation
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Hyaline Membrane Disease, Preterm Infant
Evaluation of the Neonatal Autonomic Stress During Intubations Under Propofol in a Population of Premature Infants Under 33 w'GA
Hyaline membrane disease is one of the leading causes of morbidity and mortality in premature newborns in industrialized countries.
- Trial name
- PROPOSURF (NCT03721640)
- Testing
- electrocardiogram
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Coronary Artery Bypass
Noninvasive Ventilation After Coronary Bypass Grafting
This is a prospective, quantitative, randomized, crossover study. Were included in this study 10 people in the Intensive Care Unit at University Hospital in Uberlandia, on the first day of the postoperative coronary artery bypass…
- Trial name
- Physiotherapy (NCT02352376)
- Testing
- Conventional ventilator, Specific ventilator
- Volunteers
- 10 people
- Sponsor
- Federal University of Uberlandia
Respiratory Insufficiency, Hypoxia
Prehospital CPAP vs. Usual Care for Acute Respiratory Failure
The purpose of this study is to evaluate the effectiveness of continuous positive airway pressure ventilation when applied by paramedics to individuals with severe breathing difficulties in the prehospital setting.
- Trial name
- NCT00405314
- Testing
- Continuous positive airway pressure ventilation mask
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Dalhousie University
Bronchiolitis
Non-Invasive Ventilation Versus Neurally-Adjusted Ventilatory Assistance (NAVA) for the Treatment of Bronchiolitis
This project aims to answer whether the use of a Neurally-Adjusted Ventilatory Assistance mode for non-invasive ventilation in pediatric patients with bronchiolitis results in improved comfort and reduced escalations in therapy…
- Trial name
- NCT06053684
- Testing
- Standard Non-Invasive Mechanical Servo Ventilation, Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Mechanical Servo Ventilation
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Montefiore Medical Center
Sepsis, Acute Respiratory Distress Syndrome (ARDS)
Evaluating Artificial Intelligence-Based Clinical Decision Support for Sepsis and ARDS
Sepsis and acute respiratory distress syndrome (ARDS) are common in intensive care units. Managing sepsis and ARDS is inherently complex and requires making numerous decisions under uncertainty.
- Trial name
- NCT07025096
- Testing
- Artifical Intelligence-Generated Treatment Recommendations
- Where
- United States
- Volunteers
- 355 people
- Sponsor
- University of Pennsylvania
Respiratory Failure Requiring Non Invasive Ventilation
NIV With Airway Washout for Dual Limb Ventilation: Improvement in Minute Ventilation
This is a prospective, non-randomized, non-blinded, crossover feasibility investigation to assess the safety, usability, and efficacy of the investigational mask in the hospital environment.
- Trial name
- NCT06939920
- Testing
- Non-invasive ventilation mask with airway washout, non-invasive ventilation
- Volunteers
- 20 people
- Sponsor
- Fisher and Paykel Healthcare
Invasive Ventilation
Nasal Airflow in Post-operative Patients
The goal of this investigation is to examine the effect of nasal airflow in invasively ventilated adult patients following planned surgery.
- Trial name
- NCT07468266
- Testing
- TUI-1, TUI-2
- Where
- New Zealand
- Volunteers
- 12 people
- Sponsor
- Fisher and Paykel Healthcare
Motor Neuron Disease / Amyotrophic Lateral Sclerosis
Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease
A two-arm, individual participant randomised controlled, assessor-blinded trial in 7 MND care centres across Australia will be undertaken.
- Trial name
- 3TLA (NCT05136222)
- Testing
- Intervention polysomnography
- Where
- 13 sites in Australia
- Volunteers
- 244 people
- Sponsor
- University of Melbourne
Upper Abdominal Surgery, Critical Ill Patients in SICU
Non-Invasive Respiratory Monitoring to Predict Successful Separation From Mechanical Ventilation Following Upper Abdominal Surgery
The VALUE Study is a two-phase, prospective clinical trial conducted at King Chulalongkorn Memorial Hospital (KCMH). The study evaluates the prevalence of mechanical ventilation (MV) separation failure in post-open upper…
- Trial name
- VALUE (NCT07678502)
- Testing
- High Flow Oxygen, Nasal canula oxygen
- Volunteers
- 40 people
- Sponsor
- Papawee Chennavasin
Respiratory Failure, Re-intubation Rate
High Flow Nasal Cannula Versus Non Invasive Positive Pressure Ventilation in Reducing The Rate of Reintubation
This is study aim to compare between high flow nasal canula (HFNC) and non invasive positive pressure ventilation (NIPPV) in reducing the rate of reintubation in mechanically ventilated patient with successful weaning
- Trial name
- NCT06029699
- Testing
- high flow nasal cannula, non invasive positive pressure ventilation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
INvasive Aspergillosis, Mechanical Ventilation
Diagnostic Study of Biomarkers in BAL of ICU Patients With Lung Infiltrates
The aim of this project is therefore to explore on the clinical significance of analyzing surrogate markers combined with conventional diagnostics in the ICU setting.
- Conditions
- INvasive Aspergillosis, Mechanical Ventilation, Lung Infiltrates, Diagnostics
- Trial name
- NCT01695499
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Heidelberg University
High Flow Oxygen Therapy, Non Invasive Ventilation (NIV)
Predicting the Need for Invasive Mechanical Ventilation Using Different Risk Scores
This prospective, single-center observational study aims to evaluate the predictive performance of the ROX index, modified ROX index, and HACOR score for the need for invasive mechanical ventilation in adult intensive care unit…
- Trial name
- HFNC-NIV (NCT07896616)
- Volunteers
- 84 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
ALS
Factors Associated With Success of NIPPV in ALS Patients
This is a retrospective cohort study to assess the factor associated with success of non-invasive positive ventilation in ALS patients.
- Trial name
- NCT05581771
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Seoul National University Bundang Hospital
Weaning, Chronic Respiratory Failure
Non Invasive Ventilation and Weaning : VENISE Trial
The clinical efficacy of noninvasive ventilation (NIV) has now been demonstrated in the management of acute-on-chronic respiratory failure (ACRF) of various etiologies.
- Trial name
- VENISE (NCT00213499)
- Testing
- non invasive ventilation
- Where
- France
- Volunteers
- 205 people
- Sponsor
- University Hospital, Rouen
Hypercapnic Respiratory Failure
High Flow Oxygen and Non Invasive Ventilation for Hypercapnic Respiratory Failure
this study evaluates high flow oxygen therapy in addition to non invasive ventilation (NIV) to treat hypercapnic respiratory failure.
- Trial name
- NCT03627598
- Testing
- HFNC, standard
- Where
- Tunisia
- Volunteers
- 100 people
- Sponsor
- University Hospital, Mahdia
Respiration Disorders
Non-invasive Methods of Measuring Lung Volume
Each breath humans take can be split into different measurements that clinicians can use to see how well a patient's lungs are working.
- Trial name
- NIM-LV (NCT06681467)
- Testing
- Respiratory monitoring band
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Hypoventilation
Monitoring of Non-invasive Ventilation
The purpose of this study is to determine whether clinical examination, report from ventilator software, nocturnal Sp02 and daytime arterial blood gas are sufficient as screening tools to reveal clinical relevant problems with…
- Trial name
- NCT01845233
- Where
- Norway
- Volunteers
- 67 people
- Sponsor
- Oslo University Hospital
Post-Traumatic Respiratory Failure
Efficacy of Non-Invasive Mechanical Ventilation in Early Hypoxia Secondary to Thoracic Trauma
Severe post-traumatic hypoxia is mainly due to lung contusion. The intubation rate of these patients is near 20%. Treatment before intubation is needed, is based on pain control with epidural anesthesia and oxygen.
- Trial name
- NCT00557752
- Testing
- Non-invasive ventilation
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Virgen de la Salud
Infant, Newborn, Diseases, Intubation Complication
Noninvasive Positive Pressure Ventilation During Neonatal Nasal Intubation
The goal of this study is to perform a quality control assessment of our local intubation protocol in any newborn infant requiring endotracheal intubation in the delivery room or neonatal intensive care unit at the Department of…
- Trial name
- IntubAID (NCT06139809)
- Testing
- Intubation
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich