Clinical trials: Investigation Time
Evaluate Both Technics on Procedure Duration, Characteristics and Perioperative Complications
Evaluation of a Hysteroscopic Morcellator in Hysteroscopic Treatment of Submucosal Fibroids
Hysteroscopic surgery is the gold standard for intra uterine pathology especially fibroma. Limit of this technic is duration of procedure which is correlated to operative complications.
- Trial name
- NCT02406898
- Testing
- morcellator uterine system (MH)Karl Storz, Tuttligen- Germany
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Pneumonia
Evaluation of Ventilatory Strategies During Laparoscopic Surgery
Atelectasis involving declive areas often occurs during general anesthesia and may persist postoperatively. This phenomenon could be amplified by pneumoperitoneum and Trendelenburg position.
- Trial name
- NCT01923038
- Testing
- First arm: patients ventilated with zero end expiratory pressure, Patients ventilated with Positive End Expiratory Pressure, Patients ventilated with Positive End Expiratory Pressure plus Recruitment maneuver
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Maria Vittoria Hospital
Bladder Cancer, Hematuria; Benign
PENK Methylation Test for Detecting Bladder Cancer
The primary objective of this clinical trial is to determine the sensitivity and specificity of the EarlyTect® Bladder Cancer test for bladder cancer among patients with hematuria by comparing it to the results of cystoscopy…
- Trial name
- NCT05220189
- Testing
- EarlyTect® Bladder Cancer test
- Where
- South Korea
- Volunteers
- 1,549 people
- Sponsor
- Asan Medical Center
Peripheral Artery Disease, Intermittent Claudication
Patients With Intermittent Claudication Injected With ALDH Bright Cells
The purpose of this study is to find out if aldehyde dehydrogenase bright (ALDHbr) cells taken from a patient's bone marrow can be placed safely, via intramuscular injections, into their affected calf and lower thigh muscles and…
- Trial name
- PACE (NCT01774097)
- Testing
- ALD-301
- Where
- 9 sites in United States
- Volunteers
- 82 people
- Sponsor
- The University of Texas Health Science Center, Houston
Kidney Transplant; Complications
Pulse Wave Velocity, Tacrolimus Time in Therapeutic Range and CV in African American Kidney Transplants
The primary purpose of this study is to evaluate the pulse wave velocity and vascular compliance measurements at the beginning and the end of the study while the participants are taking either extended release tacrolimus tablets…
- Trial name
- PTAAK (NCT03841097)
- Testing
- Extended Release Tacrolimus Tablets, Immediate Release Tacrolimus Capsule
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Roy D. Bloom, MD
Pregnancy
Evaluation of the Efficacy of the Becoming Parents Program
The primary aim of this study is to test the effectiveness of the Becoming Parents Program--a couple focused educational program for couples having a first child--on individual and couple well being and the parent-infant…
- Trial name
- NCT00243997
- Testing
- Becoming Parents Program
- Volunteers
- 940 people, healthy volunteers welcome
- Sponsor
- University of Washington
Moderate to Severe Chronic Obstructive Pulmonary Disease
A Continuation Study of Tilrekimig in Adults With Moderate-to-Severe Long-Term Breathing Difficulty, Known by the Medical Term of Chronic Obstructive Pulmonary Disease (COPD) to Learn About This Medicine When Used for a Long Period of Time
A Continuation Study of Tilrekimig in Adults with Moderate-to-Severe Long-Term Breathing Difficulty, Known by the Medical Term of Chronic Obstructive Pulmonary Disease (COPD) to Learn About this Medicine when Used for a Long…
- Trial name
- NCT07839884
- Testing
- Tilrekimig
- Volunteers
- 1,360 people
- Sponsor
- Pfizer
Traumatic Brain Injury
Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury
This study will look to validate predictive algorithms developed in a previous study where we collected relevant data from trauma registry and after using advanced signal-processing and machine-learning, determined prediction…
- Trial name
- RAPID-TBI (NCT05084352)
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- University of Maryland, Baltimore
Oncology
Geriatric Assessment Reporting in Real Time (GARRT) in Non-electively Hospitalized Older Cancer Patients
This study prospectively evaluates the impact of geriatric assessment reporting in real-time (GARRT) on key hospital based outcomes in a cohort of non-electively hospitalized older (> 70 years) adults with cancer.
- Trial name
- NCT03951090
- Testing
- Results of the brief geriatric assessment, No results of brief geriatric assessments
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Pulmonary Embolism
Duration of Therapeutic Anticoagulation in Patients With Pulmonary Embolism
Current management of intermediate- and high-risk pulmonary embolism is primarily based on curative subcutaneous or intravenous anticoagulation, with or without systemic fibrinolytic therapy or thrombectomy.
- Trial name
- ACEP (NCT06912009)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Knee Osteoarthritis
Diagnostic Performance of Ultrasound Imaging Technique for Femoral Condyle Cartilage Evaluation and Osteoarthritis
This study investigates the potential of the ultrasound imaging technique to diagnose the severity of knee osteoarthritis (OA). In parallel, measurements will also be conducted using Magnetic Resonance Imaging (MRI) and histology…
- Trial name
- CARTILAGE (NCT03184051)
- Where
- France
- Volunteers
- 16 people
- Sponsor
- University Hospital, Grenoble
Sleep Apnea Syndromes
Left Atrial Volume and Function Evaluation in Patients With Obstructive Sleep Apnea
The purpose of this study is to determine whether patients with obstructive sleep apnea have any changes in left atrial morphology and function evaluated by echocardiography three dimensional
- Trial name
- NCT00570115
- Where
- Brazil
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Neurodevelopment, Child Growth
Building Opportunities for Nurturing Care to Enhance Child Development in Eastern and Southern Africa
The goal of this randomized controlled trial is to adapt and test a package of interventions to provide nurturing care for children aged 0-2 years in three countries (Botswana, Kenya, Zimbabwe).
- Trial name
- BONDS (NCT07430826)
- Testing
- Friendship Bench, Infant and Young Child Feeding (IYCF) Curriculum, Play-Based Curriculum
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- University of Washington
Non-Melanoma Skin Cancer (NMSC), Benign Skin Growth
Assessment of Skin Lesions Using a Tissue Oxygen Imager Based on Protoporphyrin IX (PPIX) Fluorescence. This is an Open-label, Non-randomized, Feasibility Study That Includes a One-time Application of an FDA Approved Medication Followed by Local Imaging for Benign Skin Growth and Lesions Clinically
The primary objective of this study is the evaluation of the efficacy of the tissue oxygen imager based on PpIX DF in differentiating benign skin growth from non-melanoma skin cancer (NMSC).
- Trial name
- PPIX (NCT07201376)
- Testing
- Ameluz 10% Topical Gel, Protoporphyrin IX
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Newly Diagnosed Carcinoma of Breast, Genetic Predisposition to Disease
4R for Guideline Indicated BRCA Testing of Breast Center Patients
Currently, many breast center patients with a positive family history receive information about BRCA testing after breast cancer diagnosis, typically after definitive breast surgery or at a time point that does not allow them to…
- Trial name
- 4R (NCT01320540)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Health Risk Behaviors
Core Endurance in Healthy Young Adults
This study aimed to examine the effect of core endurance levels on upper extremity function, muscle strength and reaction time in healthy young adults.
- Trial name
- NCT06260540
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Aspiration of Food, Pediatric ALL
Ultrasound Assessment On Effectiveness of Cricoid Pressure In Paediatric Population
Cricoid pressure (CP) confers Grade IIA evidence in preventing gastric insufflation during general anaesthesia. However, a retrospective review of computed tomography scans by Dotson et al.
- Trial name
- NCT05509335
- Where
- Malaysia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Diagnostic Techniques and Procedures, Cardiac Surgical Procedure
Evaluation of a New Sonoclot Device for Heparin Management in Cardiac Surgery
The SONOCLOT Analyzer (S1; Sienco, Inc. Boulder, CO USA, Model DP-2951) is used to perform kaolin-based activated clotting time as routine monitor of heparin therapy in patients undergoing cardiac operations.
- Trial name
- SONEW (NCT02588976)
- Testing
- Sonoclot Analyzer
- Volunteers
- 30 people
- Sponsor
- Triemli Hospital
Mental Health
Seguimos Avanzando - Latino Youth Coping With Discrimination
The overall objective of this study is to investigate mediators and moderators at multiple ecological (individual, family/peer and school/neighborhood levels) and time-scale (micro- and macro-time) levels in the link between…
- Trial name
- NCT04875208
- Where
- United States
- Volunteers
- 886 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Asthma
A Study to Evaluate the Onset of Effect and Time Course of Change in Lung Function With Benralizumab in Severe, Uncontrolled Asthma Patients With Eosinophilic Inflammation
The purpose of this study is to investigate the onset and maintenance of effect of benralizumab on lung function, blood eosinophils, asthma control metrics and quality of life during 12-week treatment in patients with…
- Trial name
- SOLANA (NCT02869438)
- Testing
- Benralizumab
- Where
- 54 sites in United States, Chile and 4 more
- Volunteers
- 233 people
- Sponsor
- AstraZeneca
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