Clinical trials: Iodine
Iodine Deficiency
Prevalence of Iodine Deficiency in Remote Communities of Haiti
Haiti is one of the few remaining countries that is at risk of iodine deficiency disorders. In the 2018 survey, iodized salt was found in <20% of households and iodine excretion from non-pregnant and pregnant women suggested…
- Trial name
- NCT05275452
- Testing
- No intervention
- Where
- Haiti
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Hypothyroidism, Pregnancy Related
Normal Range of TSH and FT4 in Pregnancy
Physiological changes necessitate the use of pregnancy-specific reference ranges for thyrotrophin (TSH) and free T4 (FT4) to diagnose thyroid dysfunction during pregnancy.
- Conditions
- Hypothyroidism, Pregnancy Related, Thyroid, Dysfunction
- Trial name
- NRTSHTURKEY (NCT04860622)
- Testing
- Serum thyroid function tests
- Where
- Turkey (Türkiye)
- Volunteers
- 528 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Iodine Deficiency
Variability of Daily Iodine Intake: The Effects of Intra- and Inter-individual Variability in Iodine Nutrition Studies
Iodine status in populations is assessed using urinary iodine concentration (UIC) measured in spot urine samples. The iodine intake is classified as deficient, sufficient, or excessive iodine based on the median UIC (mUIC).
- Trial name
- VIOLET (NCT03731312)
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iodine Bioavailability
Bioavailability of Iodine for Natural Kelp and Iodized Salt in Young Adults
Iodine is an essential micronutrient for the production of thyroid hormones and its deficiecny remains a global problem impairing health.
- Trial name
- NCT04933279
- Testing
- iodine-containg spareribs soup, intrinsic iodine in natural kelp
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Liu Xiao Bing
Iodine Bioavailability
Seaweed, the Food Matrix, and Iodine Bioavailability
This study explores the influence of the food matrix of seaweed-containing food products on iodine bioavailability. The investigation will ascertain whether iodine bioavailability (as a percentage of the dose ingested that is…
- Trial name
- IoBio (NCT04867291)
- Testing
- Pizza, Seaweed Sheets, Seaweed Powder
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Nodule Solitary Thyroid, Toxic Multinodular Goiter
An Assessment of the Occurrence of Hypothyroidism in Patients Treated With RAI for Hyperthyroidism.
Low RAIU in patients with hyperthyroidism represents a common obstacle in the treatment with RAI. Therefore, a higher dose of RAI must be administered to cure hyperthyroidism in these patients.
- Conditions
- Nodule Solitary Thyroid, Toxic Multinodular Goiter, Radioactive Iodine-Induced Hypothyroidism
- Trial name
- NCT04663451
- Testing
- radioacive iodine therapy
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitair Ziekenhuis Brussel
Iodine Deficiency
Climat Impact on Urinary Iodine Concentration
Urinary iodine concentration (UIC) is the recommended biomarker of iodine status in populations. Yet, the influence of climate on UIC remains unclear.
- Trial name
- LION (NCT03215680)
- Testing
- Climate
- Where
- 2 sites in South Africa, Tanzania
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iodine Deficiency
Caribbean Island Urinary Iodine Survey 2018
Many of the Caribbean island nations have no data on iodine status in their populations. Iodine deficiency in children can reduce IQ but can be easily corrected through a program of salt iodization.
- Trial name
- CRUISE (NCT04388540)
- Where
- 10 sites in Antigua and Barbuda, Barbados and 8 more
- Volunteers
- 3,080 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Covid19, Povidone Iodine Adverse Reaction
Phase I/II Trial of Povidone-iodine (PVP-I) Nasal Swab For Preventing COVID-19 Spread in Healthy Subjects
Title: Phase I/II Trial (Safety and Dosing) of Povidone-iodine (PVP-I) Nasal Swab For Preventing COVID-19 Spread in Healthy Subjects: Summary: This study will evaluate in a PH I/II trial in healthy volunteers the safety and…
- Trial name
- NCT04510402
- Testing
- Povidine iodine nasal swabs
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Iodine Deficiency, Pregnancy Related
Assessment of Dried Blood Spot Thyroglobulin and Urinary Iodine Concentration in Pregnant Women
To avoid iodine deficiency and its consequences in pregnant women and their offspring, women should reach a sufficient iodine intake long before conception.
- Trial name
- STRIPE (NCT03176706)
- Testing
- no intervention
- Where
- New Zealand
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Pregnancy, Iodine Deficiency
Iodine Nutrition During Pregnancy and Related Neonatal Physical Development
Recent studies have found, in both developed and developing countries, there is still a considerable number of pregnant women in iodine deficiency status.Our overall aim is to monitor iodine status of pregnant women in China, and…
- Trial name
- NCT02586220
- Where
- 2 sites in China
- Volunteers
- 250 people
- Sponsor
- qingya tang
Hyperthyroidism/Thyrotoxicosis, Hyperthyroidism; Goiter
Iodinated Contrast Media Induced Hyperthyroidism
The proper synthesis of thyroid hormones is dependent on adequate iodine supply. The mean daily iodine intake recommended by World Health Organization is 150 mg.
- Conditions
- Hyperthyroidism/Thyrotoxicosis, Hyperthyroidism; Goiter, Iodine Induced Thyrotoxicosis, Contrast Media Adverse Reaction
- Trial name
- NCT04304794
- Testing
- Administration of iodinated contrast media, Prophylactic administration of antithyroid drugs before iodinated contrast media exposure
- Volunteers
- 36 people
- Sponsor
- Medical University of Warsaw
The Effect of Iodine and BPA on AITD in Reproduction Women
The Relationship Between Urine Iodine, Urine Bisphenol A and Autoimmune Thyroid Disease in Reproductive Women
Autoimmune thyroid disease (AITD) is the main cause of hypothyroidism in reproduction women, iodine and bisphenol A are the environmental factors for AITD.
- Trial name
- NCT03932487
- Testing
- urinary iodine and urine BPA
- Where
- China
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Xiaomei Zhang
Patients With a Thyroid Tumor Who Received Radioactive Iodine Treatment
Thyroid Cancer Database
Thyroid cancer database collects clinical and laboratory data from patients with a thyroid tumor who received radioactive Iodine treatment.
- Trial name
- NCT04031638
- Testing
- Radioactive Iodine treatment
- Where
- France
- Volunteers
- 2,300 people
- Sponsor
- Centre Georges Francois Leclerc
Iodine Deficiency Goiter, Infant Development
Community Salt Testing and Relation of Iodine Intake to Visual Information Processing of Ethiopian Infants
This study evaluated efficacy of iodized salt for mothers and their six-month-old infants' thyroid hormones and visual information processing.
- Trial name
- NCT03889431
- Testing
- Iodine capsule, Iodized Salt
- Where
- Ethiopia
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Iodine Bioavailability
Bioavailability of Iodine in Cow's Milk in Swiss Adults
Iodine deficiency remains a global problem impairing health and development in affected populations. Although there has been remarkable global progress against iodine deficiency, mild and moderate iodine deficiency remain common…
- Trial name
- BICOM (NCT03590431)
- Testing
- extrinsic iodine in milk, intrinsic iodine in milk, water iodine solution
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Isabelle Herter-Aeberli
Urine Iodine
Urine Iodine Levels of Surgical Staff
Objective: The routine use of topical iodinated antiseptic could be a possible cause of iodine contamination. The aim of this study is to evaluate iodine concentrations in operation-room staff who routinely use iodine-containing…
- Trial name
- NCT03845777
- Testing
- Using Antiseptic solution
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Iodine Excess in Pregnancy, Selenium Excess in Pregnancy
The Correlation Between Iodine and Selenium Status in Pregnancy and Risk of Thyroid Disease
Two hundred and ninety pregnant women with gestational age less than 20 weeks will be recruited in this study. Selenium and iodine conditions, and risk of thyroid disease will be monitored until termination of pregnancy, with…
- Conditions
- Iodine Excess in Pregnancy, Selenium Excess in Pregnancy, Iodine Deficiency in Pregnancy, Selenium Deficiency in Pregnancy
- Trial name
- NCT03761602
- Testing
- Not applicable (for observational studies)
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Rongrong Li
Iodine Reaction, Iodine Compounds Overdose
The Effect of Iodine Intakes on Maternal and Infant Health and the Study of Iodine RNI for Different Stages of Pregnancy
This study determined the effects of different iodine intake on the maternal and infant health and provide evidence for studying the RNI and UL of iodine in pregnant women. 1.
- Conditions
- Iodine Reaction, Iodine Compounds Overdose, Pregnancy Related
- Trial name
- NCT03710148
- Testing
- Natural exposure of deficient or excessive iodine
- Where
- 3 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Wanqi Zhang
Dietary Intervention, Pregnancy Jail
Group Education to Improve the Iodine Nutrition in Pregnancy: Cluster Randomized Trial
The purpose of this study is to assess the effectiveness of individual education versus group education about dietary habits and iodine supplementation to decrease iodine deficiency in pregnant women
- Conditions
- Dietary Intervention, Pregnancy Jail, Iodine Deficiency
- Trial name
- NCT01301768
- Testing
- Group Education
- Where
- Spain
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina