Clinical trials: Ischaemic Stroke
Ischemic Stroke
A Study to Evaluate the Effect of Diltiazem on the Pharmacokinetics (PK) of BMS-986141 in Healthy Subjects
This study is to evaluate the effect of dilitazem on the single-dose PK of BMS-986141 with parameters like Cmax, AUC(INF), and AUC(0-T).
- Trial name
- NCT02922452
- Testing
- BMS-986141, Dilitazem
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Cerebral Small Vessel Diseases, Cadasil
Taiwan Associated Genetic and Nongenetic Small Vessel Disease
The TAG-SVD enrolled patients with clinical and neuroimaging features of cerebral small vessel disease (CSVD). All enrolled patients will receive next-generation sequence (NGS) with probes designed to target five candidate CSVD…
- Conditions
- Cerebral Small Vessel Diseases, Cadasil, HTRA1-Related Autosomal Dominant Cerebral Angiopathy, COL4A1-Related Brain Small Vessel Disease With Haemorrhage
- Trial name
- TAG-SVD (NCT05473637)
- Testing
- MRI
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Calcified Cerebral Embolism
Calcified Cerebral Embolism: a Descriptive Study in a Large Single Center Cohort
Calcified cerebral embolism (CCE) is a relatively rare but underdiagnosed cause of infarction. CCE diagnosis is made by CT. Radiological characteristics of CCE have been reported in small case series.
- Trial name
- CCE Cohorte (NCT06309069)
- Testing
- None, purely observational study
- Where
- France
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Stroke, Vascular Diseases
Passive Limb Movement Study
Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance.
- Conditions
- Stroke, Vascular Diseases, Ischemic
- Trial name
- PLM (NCT05935670)
- Testing
- Ischemic Conditioning
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Stroke
Cortical Ischemic Stroke and Serotonin
In this study the investigators want to test the hypotheses that, serotonergic neuromodulation increases perilesional neuroplasticity, leading to improved behavioural outcomes through a more efficient allocation of functional…
- Trial name
- CISS (NCT02865642)
- Testing
- Serotonin Uptake Inhibitors
- Where
- 2 sites in Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ischemic Stroke
Preliminary Study of Pharmacokinetics of Ginkgolides Meglumine Injection.
To explore the rule of absorption, distribution, metabolism and elimination after intravenous administration of Ginkgolides Meglumine Injection healthy subjects.
- Trial name
- NCT02046031
- Testing
- Ginkgolides Meglumine Injection
- Where
- China
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Jiangsu Kanion Pharmaceutical Co., Ltd
Stroke, Acute Coronary Syndrome
Factors Associated With Perioperative Outcomes in Non-emergency Surgery
This epidemiological study investigates the association of recent stroke, acute coronary syndrome or pneumonia and adverse perioperative outcomes following elective non-cardiac and cardiac surgery using routinely collected UK…
- Conditions
- Stroke, Acute Coronary Syndrome, Pneumonia
- Trial name
- NCT02455492
- Testing
- stroke or myocardial infarction or pneumonia
- Volunteers
- 266,436 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Atherosclerosis
Progression of Early Subclinical Atherosclerosis
The overall objective of this study is to characterize the prevalence and progression rate of subclinical atherosclerotic lesions and to study their association to the imaging characteristics of atheroma plaques and to the…
- Trial name
- PESA (NCT01410318)
- Where
- Spain
- Volunteers
- 4,184 people, healthy volunteers welcome
- Sponsor
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Stroke
Guideline-recommended Basic Parameter Adherence in Neurocritical Care Patients
The aim of the planned study project is to assess the current situation regarding the treatment of patients with severe stroke at the neuro-critical care unit.
- Trial name
- NORMONICU (NCT06367543)
- Testing
- Time in therapeutic range of vital parameters
- Where
- Germany
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- University of Giessen