Clinical trials: Ischemic Disease
Ischemic Heart Disease, Congestive Heart Failure
The Influence of Different Training Regimens on Electrical Stability Following Myocardial Infarction
The hypothesis of the study is that aerobic conditioning following acute heart attack will improve autonomic function and electrical stability of the heart.
- Trial name
- NCT01912690
- Testing
- aerobic training, aerobic and strength training
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
ST Elevation (STEMI) Myocardial Infarction
LA Strain in Predicting Early Complication in STEMI After PPCI
The goal of this observational study To evaluate the predictive value of left atrial strain for in-hospital outcomes in patients with ST-segment elevation myocardial infarction undergoing PPCI.
- Trial name
- NCT07263282
- Testing
- 2D echocardiography
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Assiut University
Subarachnoid Haemorrhage (SAH), Delayed Cerebral Ischemia
Metabolomics in Subarachnoid Hemorrhage
The goal of this observational study is to learn whether blood and cerebrospinal fluid markers, combined with clinical, imaging and brain monitoring data, can help predict the outcome of adults with spontaneous subarachnoid…
- Trial name
- NeuroMetas (NCT07865182)
- Testing
- Blood and cerebrospinal fluid sampling
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Unidade Local de Saude Sao Jose
Acute Coronary Syndrome, Coronary Artery Disease
Salts of Clopidogrel: Investigation to ENsure Clinical Equivalence
Clopidogrel besylate (CB) is not differentiated relative to the orignal clopidogrel hydrogen sulfate (CHS) in the pharmacokinetics and in antiplatelet potency in healthy volunteers.
- Conditions
- Acute Coronary Syndrome, Coronary Artery Disease, Ischemic Stroke, Peripheral Artery Disease
- Trial name
- SCIENCE (NCT02126982)
- Where
- Greece
- Volunteers
- 1,500 people
- Sponsor
- University of Ioannina
Coronary Artery Disease(CAD)
Curative Effect Evaluation of Danlou Tablet on Coronary Artery Disease Not Amenable to Revascularization
The purpose of this study is to determine whether Danlou Tablet is effective in the treatment of coronary artery disease not amenable to revascularization on the basis of western medicine therapy.
- Trial name
- NCT03072082
- Testing
- Danlou Tablet, Aspirin Enteric-coated Tablets, Clopidogrel Hydrogen Sulfate 75 MG Oral Tablet
- Volunteers
- 440 people
- Sponsor
- Jun Li
Coronary Artery Disease, Coronary Artery Bypass Graft (CABG)
Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vein Harvesting.
This randomized, double-blind clinical trial aims to evaluate the impact of photobiomodulation therapy on postoperative outcomes in patients undergoing coronary artery bypass grafting (CABG).
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Graft (CABG), Surgical Wound Healing
- Trial name
- PHOTON (NCT07699679)
- Testing
- Photobiomodulation Therapy, Conventional Saphenous Vein Harvesting, No-Touch Saphenous Vein Harvesting
- Where
- Brazil
- Volunteers
- 292 people
- Sponsor
- Federal University of São Paulo
Peripheral Arterial Disease, Vascular Surgery
Remote Ischemic Preconditioning Prior to Vascular Surgery
The investigators have previously shown that elective vascular surgery is a high-risk operation with an anticipated risk of either death or heart attack of 15%.
- Trial name
- CRIPES (NCT01558596)
- Testing
- Preconditioning, Control
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- VA Office of Research and Development
Acute Myocardial Infarction
Impact of Guidelines on Cardiovascular and Economic Outcomes With Focus on Lipid Lowering Drugs
Methods: All patients <75 years registered in the Swedish Secondary Prevention after Heart Intensive care Admission registry (SEPHIA), will be followed-up within one year post-myocardia infarction (MI).
- Trial name
- GuLLD (NCT02929550)
- Testing
- Well-controlled
- Volunteers
- 5,304 people
- Sponsor
- Karolinska Institutet
Coronary Artery Disease, Coronary Artery Bypass Graft Surgery
The Effect of Listening to Holy Quran Recital on the Incidence of Delirium Post-CABG
This study is planned to check the effect of holy Quran recital on the development of delirium after conronary artery bypass graft surgery (CABG).
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Graft Surgery, Delirium, Postoperative
- Trial name
- NCT06346990
- Testing
- Holy Quran Recital
- Volunteers
- 264 people
- Sponsor
- Applied Science Private University
Myocardial Ischemia, Coronary Artery Bypass Grafting
The Effects of Allicor on Patients After Coronary Arteria Revascularization Treatment
Coronary revascularization interventions such as coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI) are the standard of surgical treatment of patients with myocardial ischemia.
- Conditions
- Myocardial Ischemia, Coronary Artery Bypass Grafting, Coronary Arteriosclerosis, Percutaneous Coronary Revascularization
- Trial name
- TEA-CART (NCT05803759)
- Testing
- Allicor
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Institute for Atherosclerosis Research, Russia
Stroke, Ischemic, Dysbiosis
A Randomized Double Blinded Placebo Controlled Study on the Effects of Dietary Supplementation With a Probiotic on Stroke Patients
The aim of this study is to determine the effects of an intervention using a commercially available probiotic in a cohort of acute stroke patients.
- Trial name
- PRISE (NCT04954846)
- Testing
- OMNi-BiOTiC SR-9
- Where
- Germany
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Delirium, Ischemic Stroke
CTSN Embolic Protection Trial
This is a prospective, multi-center, randomized effectiveness trial of the CardioGard Embolic Protection Cannula in high-risk valve surgery patients.
- Conditions
- Delirium, Ischemic Stroke, Acute Kidney Injury, Heart Valve Disease
- Trial name
- EMPRO (NCT06027788)
- Testing
- CardioGard Embolic Protection Cannula, Standard Aortic Cannula
- Where
- 24 sites in United States, Canada
- Volunteers
- 842 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Symptomatic Non-acute Intracranial Artery Occlusion, Ischemic Stroke
Randomized Clinical Trial of Endovascular Recanalization for Symptomatic Non-Acute Intracranial Artery Occlusion（REPAIR）
A multicenter, randomized, open-label, endpoint-blinded trial to compare the effects of endovascular recanalization plus aggressive medical management with aggressive medical management alone on stroke recurrence and mortality in…
- Trial name
- NCT07495969
- Testing
- Endovascular Recanalization Strategy, Aggressive Medical Management
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Feng Gao
STEMI, Anterior MI
Pressure-controlled Intermittent Coronary Sinus Occlusion (PiCSO) in Acute Myocardial Infarction
The objective of this study is to assess efficacy and safety of Pressure-controlled intermittent Coronary Sinus Occlusion (PiCSO) therapy started post flow restoration but prior to stenting during percutaneous coronary…
- Trial name
- PiCSO-AMI-I (NCT03625869)
- Testing
- PiCSO
- Where
- 17 sites in Denmark, France and 4 more
- Volunteers
- 145 people
- Sponsor
- Miracor Medical SA
Diabetic Foot Ulcer, Venous Leg Ulcer
Post-Marketing Surveillance of Dehydrated Human Amnion/Chorion Membrane (DHACM) in Non-Ischemic Chronic Wounds
The purpose of this survey is to observe the efficacy and safety of EPIFIX® dehydrated human amnion/chorion membrane (DHACM) for the treatment of intractable diabetic foot ulcers or venous leg ulcers.
- Trial name
- NCT06236750
- Testing
- EPIFIX
- Where
- 5 sites in Japan
- Volunteers
- 75 people
- Sponsor
- MiMedx Group, Inc.
Acute Kidney Injury
Acute Kidney Injury in Children Operated for Congenital Heart Disease
The purpose of this study was to investigate if repeated inflation of a blood pressure cuff applied around one leg causing mild ischemia ("remote ischemic preconditioning") could protect children operated for congenital heart…
- Trial name
- NCT01316497
- Testing
- Remote ischemic preconditioning (RIPC), Control
- Where
- Denmark
- Volunteers
- 105 people
- Sponsor
- University of Aarhus
Kidney Cancer
Robot-assisted Partial Nephrectomy With and Without Mixed Reality (REALITATEM Study)
Kidney cancer has had a raising diagnostic incidence and partial nephrectomy (PN) is the standard of care for renal masses stage cT1a and a possible treatment choice for cT1b/T2; PN may be associated to a variety of tools, such…
- Trial name
- NCT06903260
- Testing
- Mixed Reality
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hospital Moinhos de Vento
Myocardial Infarction, Acute
Mechanocardiography in Patients With STEMI
The study aim is to evaluate the capability of mechanocardiography in detecting acute myocardial ischemia in patients suffering evolving ST-segment elevation infarction.
- Trial name
- MECHANO-STEMI (NCT03441724)
- Testing
- Mechanocardiography
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- University of Turku
ST-segment Elevation Myocardial Infarction
Association Between Plasma Melatonin and No-reflow
ST-segment elevation myocardial infarction (STEMI) is an acute manifestation of coronary heart disease, remaining a frequent cause of death.
- Trial name
- NCT03306303
- Volunteers
- 1,700 people
- Sponsor
- Chinese PLA General Hospital
Atherosclerosis, Coronary Disease
Study of the Interaction Between the Cells Lining Blood Vessels and Angiotensin-Converting Enzyme
The walls of blood vessels are lined by flat cells that are responsible for releasing substance(s) that control the activity of the blood vessel. These cells are referred to as the endothelium of the blood vessel.
- Trial name
- NCT00001461
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
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