Clinical trials: Ischemic Heart Diseases
Microvascular Angina
Microvascular Assessment of Ranolazine in Non-Obstructive Atherosclerosis (MARINA)
The purpose of this study is to look at the effects of the drug Ranolazine compared to Placebo on symptoms of chest pain or chest tightness (known as angina), exercise endurance and ability, and changes in blood flow to the very…
- Trial name
- MARINA (NCT02147067)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Emory University
Coronary Artery Disease
Comparison of the HyperQ Versus Conventional Electrocardiogram (ECG) to Detect Ischemia
The purpose of the investigation is to verify the efficiency of the HyperQ™ system in detecting exercise induced ischemia, with higher specificity and sensitivity than conventional ECG Stress testing.
- Trial name
- NCT00917800
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- West German Heart Center Essen
Stable Coronary Artery Disease
Prognostic Models for People With Stable Coronary Artery Disease
There is currently no published algorithm for secondary prevention prognosis of CHD that is representative of the England GP-registered population and that includes both symptomatic and asymptomatic patients (as identified…
- Trial name
- NCT01609465
- Where
- United Kingdom
- Volunteers
- 300,000 people
- Sponsor
- University College, London
Acute Coronary Syndrome, Chronic Heart Failure
Influenza Vaccination During Coronavirus Disease 2019 Outbreak After Acute Coronary Syndrome and Chronic Heart Failure
Study Description: Background: Well-known fact that the number of cardiovascular diseases is on the rise during influenza epidemic.
- Trial name
- IV-ACS&CHF (NCT05232292)
- Testing
- Ultrix Quadri
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Samara Regional Cardiology Dispensary
Transposition of Great Vessels, Surgery
MRI Study After Arterial Switch Operation in Patients With Transposition of the Great Arteries
This study involves adolescents operated with arterial switch procedure for transposition of the great arteries during the neonatal period.
- Trial name
- NCT01916499
- Testing
- 3 tesla magnetic resonance imaging findings; coronary artery status, 3 tesla magnetic resonance imaging findings; ventricular function and morphology
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Oslo University Hospital
Coronary Artery Disease (CAD), Ischemic Heart Disease
Coroflex® ISAR NEO PMCF Study
International, Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Coroflex® ISAR NEO coronary stent system to meet EU Medical Device…
- Trial name
- rEPIC07 (NCT05698732)
- Testing
- Coroflex® ISAR NEO coronary stent system
- Where
- 26 sites in France, Spain and 1 more
- Volunteers
- 3,000 people
- Sponsor
- Fundación EPIC
Coronary Heart Disease, Cardiovascular Risk Factor
Individual Variability of Coronary Heart Disease Risk Markers and Sleep Responses to Exercise
The aim of this study is to examine the reproducibility of postprandial coronary heart disease (CHD) risk marker and sleep responses to acute exercise bouts and to quantify the magnitude of individual variability in responses…
- Conditions
- Coronary Heart Disease, Cardiovascular Risk Factor, Arterial Stiffness, Blood Pressure
- Trial name
- NCT05022498
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Socioeconomic Status, Secondary Prevention
Socioeconomic Status, Secondary Prevention Activities and Recurrence After a Myocardial Infarction
This is a nationwide cohort study on real-world patients (n≈30,000) surviving a first myocardial infarction (MI) 2006-2013 and alive to attend a routine 1-year follow-up.
- Conditions
- Socioeconomic Status, Secondary Prevention, Myocardial Infarction, Cardiovascular Disease
- Trial name
- NCT04199663
- Volunteers
- 30,191 people
- Sponsor
- Karolinska Institutet
Atrial Fibrillation, Ischemic Heart Disease
Epicardial Fat Pads Ablation During Coronary Surgery
The aim of this prospective randomized study was to assess the efficacy of ablation of the ganglionated plexi localized in the epicardial fat pads for preventing recurrences of atrial tachyarrhythmia in patients with paroxysmal…
- Trial name
- NCT02984371
- Testing
- Coronary artery bypass grafting, Epicardial ganglionated plexi ablation, implantable loop recorder
- Where
- 2 sites in Russia
- Volunteers
- 264 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Ischemic Heart Disease
Patterns of Antiacids Use in Patients With IHD Admitted to Department of Internal Medicine
There is substantial, continuing, and unexplained rise in prescribing of proton pump inhibitors. It is unknown whether their use in practice has corresponded to their licensed indications.
- Trial name
- NCT00392964
- Where
- 2 sites in Israel
- Volunteers
- 1,200 people
- Sponsor
- Rambam Health Care Campus
Ischemic Heart Disease
Sevoflurane Effect on Left Atrial Performance: A Transoesophageal Echocardiographic Study
The left atrial performance is affected by the preload as well as the afterload. The LA active pumping is increased by stretching of the LA but within limits, after which the active pumping declines.
- Trial name
- NCT03999463
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Acute Coronary Syndrome
Suxiao Jiuxin Pills in Microvascular Obstruction in Patients With Acute Coronary Syndrome
Microvascular obstruction is the severe complication of percutaneous coronary intervention (PCI) in patients with acute coronary syndrome. Microvascular obstruction after PCI is often association with poor prognosis.
- Trial name
- NCT04814121
- Testing
- Suxiao Jiuxin Pills
- Volunteers
- 198 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Coronary Artery Disease, Coronary Artery Bypass Grafting
Total Arterial Revascularization (TAR)
Total arterial revascularisation with in-situ confihuration of BITA is superior than y-graft in patients underwent CABG.
- Trial name
- NCT03753048
- Testing
- Y-Graft, In-Situ
- Where
- Russia
- Volunteers
- 880 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Stroke
Cardiac MRI in Ischemic Stroke Study
The purpose of this prospective single-center trial is to compare the safety and diagnostic value of contrast medium-enhanced cardiac magnetic resonance imaging and transesophageal echocardiography in patients with acute ischemic…
- Trial name
- CaMriSS (NCT01917955)
- Where
- 2 sites in Germany
- Volunteers
- 103 people
- Sponsor
- Charite University, Berlin, Germany
Cardiogenic Shock
Physiology of Unloading VA ECMO Trial
The goal of this clinical trial is to compare the use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) with and without left ventricular (LV) unloading in patients being treated for cardiogenic shock (CS).
- Trial name
- NCT06336655
- Testing
- IABP
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Utah
Stroke
Finding Atrial Fibrillation in Stroke - Evaluation of Enhanced and Prolonged Holter Monitoring
The purpose of this study is to assess whether repeated enhanced and prolonged ECG monitoring after ischemic stroke results in a higher detection of atrial fibrillation (/flutter) compared to usual care (at least 24 hour of…
- Trial name
- NCT01855035
- Testing
- prolonged ECG monitoring, standard care
- Where
- 4 sites in Germany
- Volunteers
- 402 people
- Sponsor
- Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH
Ischaemic Heart Disease
Motion and IntraCoronary Ecg Ischemia Development Study (MICE)
The concept of the "ischemic cascade" is generally accepted hypothesis, according to which whenever ischemia of the myocardium occurs there is a consequence of events, that always occur in a given order - diastolic dysfunction…
- Trial name
- MICE (NCT04061525)
- Testing
- Percutaneous coronary intervention with FFR measurement and intracoronary ECG registration
- Where
- Bulgaria
- Volunteers
- 30 people
- Sponsor
- University National Heart Hospital
Shock, Cardiogenic, Surgery
Validity of Cardiac Output Measurement Using Niccomo Device After Cardiac Surgery
Cardiac surgery is at high risk of low cardiac output syndrome after procedure. Monitoring cardiac function, and especially cardiac output, is important to identify cardiovascular dysfunction and to introduce and adjust optimal…
- Conditions
- Shock, Cardiogenic, Surgery, Output, Low Cardiac
- Trial name
- Niccomo-Card (NCT04643509)
- Testing
- Niccomo
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Rouen
Left Ventriclar Mass
Metformin Reduces Left Ventricular Mass in Patients With Ischemic Heart Disease
Cardiovascular disease is the most common cause of death in the world. Most of the attention in treating ischemic heart disease (IHD) is understandably directed toward treating coronary artery disease.
- Trial name
- NCT01879293
- Testing
- Metformin
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Wuhan General Hospital of Guangzhou Military Command
ST Elevation (STEMI) Myocardial Infarction
Correlation Between Triglyceride Glucose Index and Myocardial Injury Assessed by Cardiac Magnetic Resonance Imaging (CMR) in Patients With STEMI
This research aim is to investigate the correlation between triglyceride glucose index (TyG index) and myocardial infarct size, microcirculation obstruction (MVO) and intramyocardial hemorrhage (IMH) assessed by cardiac magnetic…
- Trial name
- NCT07261514
- Where
- China
- Volunteers
- 674 people
- Sponsor
- Chinese PLA General Hospital