Clinical trials: Ivf
EMBRYO IMPLANTATION
Endometrial Scratch Effect on Pregnancy Rates in Patients Undergoing Egg-donation IVF
Clinical trial about the effect of endometrial scratch on pregnancy rates in patients undergoing a treatment with in-vitro fertilization with donor eggs, when doing the endometrial biopsy during the cycle prior to the embryo…
- Trial name
- NCT03108157
- Testing
- Endometrial scratch
- Where
- Spain
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Procreatec
Depression Relapse in Women Undergoing Fertility Treatment
Symptom Tracking in Assisted Reproductive Technologies
This study assesses risk factors for depressive relapse in women undergoing fertility treatment with histories of major depressive disorder (MDD) or bipolar disorder.
- Trial name
- START (NCT01746797)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Infertility
In Vitro Maturation With in Vitro Fertilization (IVF) Compared to Mild in Vitro Fertilization
Methods of infertility treatment may involve in vitro fertilization or IVF. Though effective, IVF is complex and expensive. Methods using no gonadotropin hormone stimulation of the ovaries are being compared to mild stimulation…
- Trial name
- IVM vs IVF (NCT00867763)
- Testing
- In vitro maturation and in vitro fertilization, Low doses of gonadotropin stimulation.
- Where
- 2 sites in United States
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- Batzofin Fertility Services
Poor Responders Undergoing IVF
The Comparison of Effect of Four Different Treatment Protocols on IVF Outcomes in Poor Responders Undergoing in Vitro Fertilization.
The comparison of effect of four different treatment protocols: Antagonist/letrozole protocol, microdose flare-up protocol, Antagonist/clomiphene protocol, Antagonist on IVF outcomes in poor responders undergoing in vitro…
- Trial name
- NCT01948804
- Testing
- GnrH Antagonist/letrozole protocol (Cetrotide; serono + Femara; Novartis Pharma AG), microdose flare-up protocol (Lucrin; Abbott + Gonal F, Serono), Antagonist/clomiphene protocol (Cetrotide; serono + Klomen, Kocak pharma)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pınar Özcan Cenksoy
Infertility
IVF Treatment in Women With Immature Oocytes in Previous Cycle
In standard IVF stimulation cycle,human chorionic gonadotropin (hCG) is usually used at the end of controlled ovarian hyperstimulation (COH) as a surrogate to only the luteinizing hormone (LH) surge.
- Trial name
- NCT02368964
- Testing
- GnRH agonist 0.2 mg + hCG 250 mcg, high dose hCG 500 mcg
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Endometrial Receptivity and Success Rate of IVF
Pilot Study on Molecular Quantitation and Sequencing of Endometrial Cytokines Gene Expression and Their Effect on the Outcome of In-vitro Fertilization (IVF) Cycle
Pilot study on molecular quantitation and sequencing of endometrial cytokines gene expression and their effect on the outcome of in-vitro fertilization (IVF) Cycle
- Trial name
- NCT01809509
- Testing
- Endometrial biopsy
- Where
- 2 sites in Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infertility, Female
The Effectiveness and Safety of the Prolonged Down-regulation Protocol for Controlled Ovarian Hyperstimulation
Since the first "tube baby", Louise Brown, was born in the United Kingdom in 1978, many infertile couples have been benefitted from in vitro fertilization and embryo transfer (IVF-ET) and intracytoplasmic sperm injection (ICSI).
- Trial name
- NCT03809221
- Testing
- Triptorelin acetate
- Volunteers
- 1,892 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Immunomodulatory Drugs, Killer-cell Immunoglobulin-like Receptors (KIRs)
Effect of Immunomodulatory Treatment on IVF (in Vitro Fertilization) Outcomes in Patients With KIR AA Genotype
The aim of the study is to investigate the immune cause of recurrent implantation failure (RIF) and the role of immunomodulatory treatment in IVF (in vitro fertilization) patients that have a KIR AA genotype.
- Conditions
- Immunomodulatory Drugs, Killer-cell Immunoglobulin-like Receptors (KIRs), KIR Alleles (KIR AA)
- Trial name
- NCT06264206
- Testing
- Killer-cell immunoglobulin-like receptors (KIRs) testing
- Where
- Romania
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Calla IVF Center
IVF
Luteal Phase Estradiol Support for In Vitro Fertilization/Intracytoplasmic Sperm Injection Cycles
Optimizing in vitro fertilization (IVF) success is more important than ever, in light of new public funding of IVF in Ontario, Canada.
- Trial name
- NCT02677259
- Testing
- 17-beta estradiol, Micronized progesterone
- Volunteers
- 506 people, healthy volunteers welcome
- Sponsor
- One Fertility
Endometriosis, Omics
SH-SDU Shandong Endometriosis Reproductive Cohort
Endometriosis (EMs) is a chronic, estrogen-dependent, multi-systemic disease that affects approximately 190 million women worldwide.
- Conditions
- Endometriosis, Omics, Assisted Reproductive Technology
- Trial name
- NCT07558629
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Shandong University
Infertility, Aneuploidy
Time Lapse Assisted Embryo Selection Versus Non Invasive PGT-A Assisted Embryo Selection
This is a prospective randomised study of the evaluation of the clinical IVF results after time lapse assisted embryo selection versus Non-invasive PGT-A assisted embryo selection in subfertile women.
- Conditions
- Infertility, Aneuploidy, Chromosome Abnormality
- Trial name
- NCT05545995
- Testing
- embryo selection
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
HCG; IVF; Pregnancy Rates; ART; Chorionic Gonadotropin
Low-dose HCG as an Adjunct to Ovarian Stimulation in Subfertile Women Undergoing ART
The objective of this prospective randomized clinical trial is to investigate whether the addition of low-dose hCG to a short GnRH-agonist protocol for IVF and ovarian stimulation with rFSH from the onset of the follicular phase…
- Trial name
- HCG (NCT03423537)
- Testing
- hCG
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Anesthesia, IVF
Does Camel Milk Consumption Decrease The Efficacy Of Midazolam For Sedation
The primary aim is to verify if camel milk consumption has an impact on the amount of Midazolam needed to achieve a satisfactory level of sedation for oocyte retrieval, compared to patients never having consumed camel milk.
- Trial name
- NCT04397393
- Testing
- Midazolam
- Where
- United Arab Emirates
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Poor Ovarian Response
Novel Therapy for Poor Responders Management
Unfortunately for some infertile women, gonadotrophin administration results in a desultory ovarian response. While this is commonly due to diminished ovarian reserve, as indicated by advanced age and/or elevated basal day 3 FSH…
- Trial name
- NCT04310293
- Testing
- Femara,Grotwth hormone,HMG
- Where
- Bahrain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al Baraka Fertility Hospital
Infertility
Comparison of Transfers of Thawed Blastocysts Versus Blastocysts Derived From Thawed Bipronuclear Oocytes
The purpose of this study is to determine if cryopreservation at the blastocyst stage followed by embryo thaw and transfer is as effective as cryopreservation of bipronuclear oocytes followed by post-thaw extended culture (PTEC)…
- Trial name
- NCT01247987
- Testing
- Blastocyst cryopreservation, Bipronuclear oocyte cryopreservation
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Bruce Shapiro M.D.
PCO - Polycystic Ovaries, Infertility
Mild Stimulation Protocol Using Clomiphene Citrate for Women With PCOS Undergoing in Vitro Fertilization
Infertility is of increasing significance affecting almost 48.5 million couples around the world. Anovulation is a major cause of infertility in women with polycystic ovary syndrome (PCOS) accounting for about 80% of women with…
- Trial name
- NCT04157725
- Testing
- mild stimulation protocol: oral Clomiphene Citrate, Conventional Stimulation Protocol: will receive FSH/HMG
- Where
- Lebanon
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Pregnancy, In Vitro Fertilization
The Impact of Early Embryos Incubation on Pregnancy Rate in IVF
Frozen- thawed embryos obtained by IVF treatments are transferred to the uterus immediately following thawing or after incubation for additional 24-72 hours. The two methods are routine in IVF laboratories.
- Trial name
- IVF-2010 (NCT01287273)
- Where
- Israel
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Martha Dirnfeld
In Vitro Fertilisation (IVF) Treatment
Effect of Oxytocin and Vasopressin Antagonists on Uterine Contractions
The main purpose of this clinical research trial was to evaluate the effects of barusiban and atosiban compared to placebo on luteal phase uterine contractions in oocyte donors supplemented with progesterone.
- Trial name
- OVANCON (NCT00587327)
- Testing
- Barusiban, Atosiban
- Where
- 5 sites in Belgium, Czechia and 1 more
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Fertilization in Vitro
Ejaculation Abstinence Time and Assisted Reproductive Technology Outcomes
The goal of this clinical trial is to learn if reducing the ejaculation abstinence time can improve the outcome of assisted reproductive technology.
- Trial name
- NCT06410417
- Testing
- Shorten abstinence time
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Infertilities
Comparison of the Efficiency of Intra-uterine Insemination and in Vitro Fertilization in Women Over 37 Years
As age increases the chances for a woman to become pregnant decrease as well spontaneously as through assisted reproductive technologies (ART).
- Trial name
- AMPAGE (NCT02001870)
- Testing
- In Vitro Fecundation (IVF), Intra Uterine Insemination (IUI)
- Where
- 12 sites in France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse