Clinical trials: Joint Stiffness
Knee Osteoarthritis
Improvement in Pain and Function Following a Physiotherapy Program in Older Adults With Knee Osteoarthritis
This study evaluates the combination of a therapeutic exercise program and dry needling in the treatment of knee osteoarthritis in older adults.
- Trial name
- NCT02698072
- Testing
- Therapeutic exercise, Dry needling
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Rey Juan Carlos
Osteoarthritis, Knee
A Pilot Study Assessing the Treatment Responsiveness of a Novel Osteoarthritis Stiffness Scale
Osteoarthritis is a common, chronic, progressive, skeletal, degenerative disorder that frequently affects several joints such as knee, hip, spine and hands.This placebo-controlled clinical trial assessed the effects of naproxen…
- Trial name
- NCT03570554
- Testing
- Naproxen Sodium (Aleve, BAY117031), Acetaminophen ER, Celecoxib
- Where
- 5 sites in United States
- Volunteers
- 41 people
- Sponsor
- Bayer
Ankylosing Spondylitis (AS)
The Relationship Between Arterial Stiffness and Pulmonary and Extrapulmonary Features in Ankylosing Spondylitis
The aim of this study was to investigate the relationship between arterial stiffness and pulmonary and extrapulmonary features in patients with ankylosing spondylitis.
- Trial name
- NCT06739369
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Joint Pain, Stiffness, Function
Instaflex and Joint Pain in Community Adults
The primary purpose of this study is to assess the effect of 8-weeks ingestion of the Instaflex Joint Support supplement (Direct Digital, Charlotte, NC) compared to placebo on joint pain, stiffness, and function (questionnaires…
- Trial name
- NCT01956500
- Testing
- Instaflex
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Thumb Joint Stiffness
Electrical Stimulation to Recover Greater Range of Motion After Surgery
Background One of the potentially debilitative complications of operative repair and subsequent immobilization is stiffness that appears secondary to inflammation and adhesions.
- Trial name
- NCT01082432
- Testing
- electrically induced muscle activation
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Université Joseph Fourier
Hyperuricemia or Gout, Hypertension
Effect of Dotinurad in Hyperuricemia With Hypertension
The effect of dotinurad on CAVI (cardio-ankle vascular index) will be compared with that of febuxostat in patients with hyperuricemia complicated by hypertension.
- Trial name
- DIANA-NEXT (NCT06834230)
- Testing
- Dotinurad, Febuxostat
- Where
- Japan
- Volunteers
- 360 people
- Sponsor
- Saga University
Rheumatoid Arthritis, Stiffness, Aortic
Methotrexate, Blood Pressure and Arterial Function in Rheumatoid Arthritis
The investigators will study the effects of methotrexate on blood pressure, arterial stiffness and endothelial function in patients with rheumatoid arthritis.
- Conditions
- Rheumatoid Arthritis, Stiffness, Aortic, Endothelial Dysfunction, Cardiovascular Risk Factor
- Trial name
- NCT03254589
- Testing
- Methotrexate, Sulfasalazine, Other DMARDs
- Where
- Australia
- Volunteers
- 124 people
- Sponsor
- Flinders University
Rheumatoid Arthritis
Prednisone Timed-Release Tablet (TRT) Study: Modified-Release (MR) Formulation of Prednisone Compared to Standard Immediate-Release (IR) Prednisone in Participants With Rheumatoid Arthritis
The objective of this study is to investigate if low doses of prednisone MR formulation, given at night and, with active drug release at 2 am, are more effective in controlling joint stiffness, and other disease symptoms of…
- Trial name
- NCT00146640
- Testing
- MR Prednisone, IR Prednisone
- Where
- 24 sites in Germany, Poland
- Volunteers
- 288 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Hypermobile EDS (hEDS), Hypermobile Ehlers-Danlos Syndrome
Hamstring Strengthening in Hypermobile Conditions
The goal of this clinical trial is to determine how strengthening the hamstring muscles affects the knee joint in people living with hypermobility spectrum disorders (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS).
- Conditions
- Hypermobile EDS (hEDS), Hypermobile Ehlers-Danlos Syndrome, Hypermobile Spectrum Disorder, Hypermobility Type Ehlers-Danlos Syndrome
- Trial name
- NCT07626957
- Testing
- Progressive resistance exercise with an emphasis on eccentric hamstring loading.
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Arthritis, Joint Pain
A Controlled Study to Evaluate the Effects of a Topical Cream on Symptoms of Arthritis, Joint, and Muscle Pain
This is a randomized, triple-blind, controlled clinical trial evaluating the effects of Saje Pain Release Joint \& Arthritis Cream on symptoms of arthritis, joint pain, and muscle pain in adults aged 20-65.
- Conditions
- Arthritis, Joint Pain, Muscle Pain, Musculoskeletal Pain
- Trial name
- NCT07767669
- Testing
- Intervention (Saje Pain Release Joint & Arthritis Cream)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Saie Beauty
Arthritis, Rheumatoid
Dataglove to Measure Joint Stiffness in Patients With Arthritis
This study will investigate if an electronic dataglove can be used to measure joint stiffness in patients with Rheumatoid Arthritis.
- Trial name
- NCT01705834
- Where
- United Kingdom
- Sponsor
- Western Health and Social Care Trust
Low Back Pain, Thoracic
Investigation of Regional Interdependence of the Hip and Spine in Baseball Players With Low Back Pain
Low back pain (LBP) is a common musculoskeletal symptom in athletes. More than 40% percent of high school baseball players reported incidents of LBP during the previous year.
- Trial name
- NCT06252740
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Stiffness; Spine, Mobility Limitation
Comparison of Active Isolated Stretching Versus Myofascial Release of Knee Joint in Office Workers
"Office workers often spend long hours sitting, which can lead to stiffness and reduced mobility. By studying these two techniques AIS and MFR, we can determine which one is more effective in helping office workers to improve…
- Trial name
- NCT06352450
- Testing
- Active isolated stretching (AIS), Myofascial release (MFR)
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Superior University
Shoulder Stiffness
Can Vitamin C Reduce the Risk of Postoperative Shoulder Stiffness?
Postoperative shoulder stiffness is a common complication after shoulder surgery (incidence 10-15%). The symptoms consist primarily in a painful impairment of the mobility of the glenohumeral joint, usually after initially good…
- Trial name
- VitC (NCT04472000)
- Testing
- Vitamin C
- Where
- 2 sites in Switzerland
- Volunteers
- 46 people
- Sponsor
- Lindenhofgruppe AG
Rheumatoid Arthritis
A Comparison of Two Electronic Gloves in the Measurement of Joint Movement in Patients With Rheumatoid Arthritis
In this study we will compare two electronic goniometric gloves to see if they can be used in research on joint movement in arthritis.
- Trial name
- NCT02026245
- Testing
- Data gloves to perform movements
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Ulster
Pain, Stiffness
Telerehabilitation for Knee Osteoarthritis: Study Protocol
Patient Recruitment and Enrolment All patients diagnosed with knee OA who present at Artros Medical Center for an orthopaedic specialist consultation will undergo a radiological examination.
- Conditions
- Pain, Stiffness, Physical Function
- Trial name
- NCT07137897
- Testing
- Telerehabilitation, Control group
- Where
- Slovenia
- Volunteers
- 118 people
- Sponsor
- University of Novo Mesto
Osteoarthritis, Knee, Osteoarthritis
Low Intensity Pulsed Ultrasound Versus High Intensity Continuous Ultrasound Therapy in Knee Osteoarthritis
To compare the effects of low intensity pulsed ultrasound with high intensity continuous ultrasound in knee osteoarthritis
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Rheumatic Diseases, Musculoskeletal Diseases
- Trial name
- NCT04406337
- Testing
- Low intensity pulsed ultrasound, High intensity continuous ultrasound
- Where
- Burma
- Volunteers
- 86 people
- Sponsor
- Ministry of Health and Sports, Myanmar
Neck Pain
Bio-mechanical Reasoning and Lateral Specificity of Upper Cervical Joint Mobilization
Participants with limited neck rotation are recruited to determine if manual therapy (joint stretching) techniques applied in a bio-mechanically correct sequence will improve neck motion, function and pain better than if the…
- Trial name
- NCT04054869
- Testing
- Bio-mechanically correct manual therapy at the cervical atlanto-axial joints, Bio-mechanically in-correct manual therapy at the cervical atlanto-axial joints
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Andrews University
Arthritis, Rheumatoid, Arthritis, Psoriatic
Impact of Nurse-led Programme With Carotid Ultrasound on Addressing Cardiovascular Risk in Patients With Arthritis
Elevated CVD risk is a significant public health problem that contributes greatly to the increased morbidity and shortened lifespan of individuals with RA and PsA.
- Trial name
- NCT03625089
- Testing
- Atorvastatin
- Where
- Hong Kong
- Sponsor
- Chinese University of Hong Kong
Knee Osteoarthritis
Knee Ligament Stiffness Across Ethnicities Before and After Osteoarthritis Treatment
This prospective clinical study aims to establish normative values of knee ligament stiffness across different ethnic populations using shear wave elastography (SWE) and to investigate biomechanical alterations associated with…
- Trial name
- NCT07744789
- Testing
- Shear Wave Elastography, Ultrasound-Guided Injection Therapy
- Where
- Taiwan
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital