Clinical trials: Kinetic Control
Skeletal Muscle Protein Synthesis in Elderly, Protein Kinetics
Effect of Low Intensity Exercise and Protein Intake on Skeletal Muscle Protein Synthesis in Elderly
Maintenance of skeletal muscle mass is crucial during lifespan to retain health and functional autonomy. Sarcopenia, being the loss of muscle mass during aging, is a well-known phenomenon in the elderly and a major challenge…
- Conditions
- Skeletal Muscle Protein Synthesis in Elderly, Protein Kinetics, Sarcopenia
- Trial name
- NCT01640145
- Testing
- Protein, Exercise
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Stroke
Effect of Soleus Muscle Kinetic Control Training on Gait and Electromyographic Activity in Patients With Stroke
this study was designed to investigate the effect of soleus muscle kinetic control training on Gait and electromyographic activity of the calf muscle in patients with stroke
- Trial name
- EMG (NCT07309081)
- Testing
- soleus kinetic control, conventional therapy
- Volunteers
- 40 people
- Sponsor
- Cairo University
Respiratory Infection (for Example, Pneumonia, Bronchitis), Respiratory Infection Virus
Kinetics and Metabolism of Nicotinamide Provided as a Dietary Supplementation
The diet of patients with reduced tryptophan serum levels that are either hospitalized for acute respiratory infection or treated for chronic inflammatory diseases such as inflammatory bowel diseases (in- or outpatients) is…
- Conditions
- Respiratory Infection (for Example, Pneumonia, Bronchitis), Respiratory Infection Virus, Community Acquired Pneumonia (CAP), COPD Acute Exacerbation
- Trial name
- CICR-NAM_PK (NCT07156929)
- Testing
- Controlled-ileocolonic-release nicotinamide (CICR-NAM): 500 mg/d, Controlled-ileocolonic-release nicotinamide (CICR-NAM): 1000 mg/d
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- University Hospital Schleswig-Holstein
Healthy
How Eccentric Closed Chain Training Affects Knee Strength and Muscle Properties in Soccer Players
The goal of this study is to learn whether a 6-week lower-body training program using closed kinetic chain (CKC) exercises with slow, controlled movements (called "eccentric time under tension") can improve leg muscle strength…
- Trial name
- NCT06987344
- Testing
- Field-based closed kinetic chain exercise with progressively increased time under tension, Regular soccer training routines
- Where
- Chile
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Americas - Chili
Kinetic Control, Dysfunction
Effect of Kinetic Control Exercise on Shoulder Dysfunction Post Mastectomy
The purpose of this study is to evaluate the effect of kinetic control exercises on shoulder dysfunction in post-mastectomy.
- Conditions
- Kinetic Control, Dysfunction, Shoulder, Mastectomy
- Trial name
- NCT07023913
- Testing
- kinetic Control exercises, traditional treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Low Back Pain
Kinetic Control Training Versus Core Stability Exercises on Proprioception and Spatiotemporal Gait Parameters in Chronic Non-specific Low Back Pain
This study will be conducted to comapre between kinetic control training versus core stability exercises on proprioception and spatiotemporal gait parameters in chronic non-specific low back pain.
- Trial name
- CNSLBP (NCT07683676)
- Testing
- Kinetic control exercises, Core stability exercises, conventional physical therapy
- Volunteers
- 60 people
- Sponsor
- Cairo University
Influenza
Phase II Study to Investigate the Kinetics of the Immune Response Generated by Influenza Virus Vaccine.
The primary objective of this study was to perform a variety of assays on blood, serum, nasal wash and cell samples obtained from healthy adult subjects for the purposes of developing assays for application in the further…
- Trial name
- NCT00192309
- Testing
- CAIV-T, TIV
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Urinary Bladder Neoplasm, Transitional Cell Carcinoma
CTC Quantification During TURBT and PKVBT of Transitional Cell Carcinoma in Purging Fluid and Blood
Transurethral resection of bladder tumor (TURBT) is usually performed in a piecemeal technique. Tumor fragmentation and cell spilling could be responsible for high recurrence rates.
- Conditions
- Urinary Bladder Neoplasm, Transitional Cell Carcinoma, Urogenital Neoplasms, Circulating Tumor Cell
- Trial name
- NCT04811846
- Testing
- Bipolar transurethral resection of bladder tumor (TURBT), Bipolar transurethral plasma kinetic vaporization of bladder tumor (PKVBT)
- Where
- 2 sites in Austria
- Volunteers
- 40 people
- Sponsor
- University Teaching Hospital Hall in Tirol
Gait
Normative Database for Gait Analysis on the GRAIL UZ Gent
The aim of this study is to collect a large set of norm/control data on an instrumented treadmill (the Gait Real-time Analysis Interactive Lab - GRAIL) at the university hospital of Ghent for the purpose of clinical studies as…
- Trial name
- B670201942108 (NCT04987346)
- Testing
- Walking on an instrumented treadmill, Walking on an instrumented treadmill while dual-tasking
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Caffeine, Biomechanics
Effects of Caffeine Ingestion on the Biomechanics of Healthy Young Subjects
Caffeine is one of the few supplements that have enough scientific evidence to state that can notably improve performance, as different remarkable organizations in the sports nutrition context have classified it as an ergogenic…
- Conditions
- Caffeine, Biomechanics, Fatigue, Injuries
- Trial name
- NCT06039358
- Testing
- Caffeine., Cellulose.
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Infertility
Type of Gonadotropin and Embryo Kinetics of Development
The study is proposed to determine the effect of three types of gonadotropins that are currently used in protocols of controlled ovarian stimulation in women undergoing in vitro fertilization techniques on the kinetics of…
- Trial name
- PEM-ESD (NCT02402192)
- Testing
- Corifollitropin alfa
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Asthma (Part 1), COPD (Part 2)
Two-part Safety, Tolerability, Pharmacodynamic and -Kinetic Study of Inhaled AZD8871 in Asthmatic and COPD Subjects
This is a phase I, randomised, placebo-controlled 2-part study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD8871 delivered by inhalation, in asthmatic and chronic obstructive pulmonary disease…
- Trial name
- NCT02573155
- Testing
- Dose 1, AZD8871 50 μg (Part 1), Dose 2, AZD8871 100 μg (Part 1), Dose 3, AZD8871 300 μg (Part 1)
- Where
- 2 sites in United Kingdom
- Volunteers
- 134 people
- Sponsor
- AstraZeneca
Chronic Hepatitis B
A Phase 1b Study Assessing GS-7340 in Treatment-Naive Adults With Chronic Hepatitis B
This is an open-label study evaluating multiple doses of GS-7340 versus Tenofovir disoproxil fumarate (TDF).
- Trial name
- NCT01671787
- Testing
- GS-7340, Tenofovir disoproxil fumarate
- Where
- 19 sites in United States, Australia and 3 more
- Volunteers
- 51 people
- Sponsor
- Gilead Sciences
Appetite Depressant, Overweight
Safety, Tolerability, Kinetics and Efficacy Study of Hoodia Gordonii Purified Extract (PYM50717)
The objective of this clinical study was to assess the safety, tolerability, efficacy (effects on appetite scores, food intake) and plasma kinetics of Hoodia gordonii purified extract (H.g.PE), when consumed twice-daily for 2 or…
- Conditions
- Appetite Depressant, Overweight, Body Weight
- Trial name
- NCT01306422
- Testing
- Hoodia gordonii purified extract (H.g.PE)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Motor Control Retraining, Close Kinetic Chain Exercises
Motor Control Retraining vs Close Kinetic Chain Exercises for Pain, Function and Vastus Medialis Oblique Strength in Patients With Patellofemoral Pain Syndrome
This study compares two treatments - motor control retraining and close kinetic chain exercises - to improves the pain, VMO strength, knee function.
- Conditions
- Motor Control Retraining, Close Kinetic Chain Exercises, Patellofemoral Pain Syndrome
- Trial name
- MCR VS CKC (NCT07766083)
- Testing
- Motor Control Retraining, Close Kinetic Chain Exercises
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Faisalabad
ARDS, Sepsis Syndrome
Kinetics of Surfactant Proteins, Phosphatidylcholine and Body Water in Intensive Care Unit (ICU)
Analysis of kinetics of phosphatidylcholine and specific surfactant proteins, total body water and water turnover in patients with acute respiratory distress syndrome (ARDS) and in intensive care unit (ICU) patients by using non…
- Trial name
- NCT03371680
- Testing
- Injection of 1-13 Carbon Leucine and deuterated water
- Volunteers
- 21 people
- Sponsor
- University of Padova
Patellofemoral Pain, PFP, Flatfeet
Comparison Between Foot Segment Mulligan Mobilization and Ilium Mulligan Mobilization in Treatment Patellofemoral Pain Patients With Flatfeet: a Randomized Controlled Comparative Study
This three-arm, parallel-group randomized controlled trial will investigate the comparative effects of adding Mulligan foot-segment mobilization or Mulligan ilium mobilization to a standardized hip-knee focused exercise program…
- Trial name
- PFP (NCT07806929)
- Testing
- mobilization with movement of the foot segment, Mobilization with movement of the Ilium, Hip-knee focused exercises
- Where
- Jordan
- Volunteers
- 90 people
- Sponsor
- Cairo University
Hyperlipidemia
A Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Effects of JS401
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetcs and pharmacodynamics of single-dose of JS401 in healthy volunteers with normal or mildly elevated triglycerides.
- Trial name
- NCT06041165
- Testing
- JS401
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Shanghai Junshi Bioscience Co., Ltd.
Primary Hyperlipidemia and Mixed Dyslipidemia
Effects on Lipoprotein Metabolism From PCSK9 Inhibition Utilizing a Monoclonal Antibody
This is a randomized, double-blind, placebo-controlled trial to evaluate the effect of evolocumab, atorvastatin, and combination therapy on lipoprotein kinetics.
- Trial name
- FLOREY (NCT02189837)
- Testing
- Evolocumab, Atorvastatin
- Where
- 2 sites in Australia
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Amgen
Loiasis
Efficacy and Microfilaricidal Kinetics of Imatinib for the Treatment of Loa Loa
Background: Many people who live in west or central Africa are at risk for infection from a very small worm called Loa loa. This infection is acquired through the bite of a fly. Baby worms called microfilariae live in the blood.
- Trial name
- NCT02644525
- Testing
- Imatinib Mesylate
- Where
- Cameroon
- Volunteers
- 20 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)