Clinical trials: Knee Surgeries
Infection of Total Knee Joint Prosthesis, Aseptic Loosening of Prosthetic Joint
Surgical / Economic Effect of the Aquamantys System in Blood Management for Aseptic and Septic Revision TKA
To assess the surgical and economic effectiveness of the Aquamantys System in managing intra- and post-operative blood loss, and reducing transfusion needs in patients undergoing both aseptic and septic revision total knee…
- Trial name
- NCT02266407
- Testing
- Aquamantys System
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medtronic Surgical Technologies
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Effects of Different Relaxation Therapies on Pain and Sleep in Hip and Knee Arthroplasty Patients
Hip and knee replacement surgery is commonly performed in older adults. After surgery, many patients experience pain, limited movement, and sleep problems.
- Trial name
- NCT07354542
- Testing
- Virtual Reality-Based Relaxation, Traditional Relaxation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Arthritis Knee, Spine Fusion
Goal-directed vs Preemptive Tranexamic Acid Administration in Non-cardiac Surgery
The present study is a multi-center randomized prospective non-inferiority trial. The study's primary objective is to compare the coagulation profile upon using two different TXA administration strategies: empirical TXA…
- Conditions
- Arthritis Knee, Spine Fusion, Prostate Cancer, Arthritis of Hip
- Trial name
- NCT05957822
- Testing
- TXA, TEG6
- Where
- South Korea
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
ACL Injury, Postoperative Pain
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following ACL reconstruction surgery. 2.
- Trial name
- NCT04246554
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Knee Arthritis Osteoarthritis, Cruciate Ligament Rupture
A Retrospective and Prospective Study: Monocompartimental Knee Arthroplasty Combined With Anterior Cruciate Ligament Reconstruction Surgery - a Pilot Study
This study aims to collect datas about patient who underwent simultaneous monocompartimental knee replacement and anterior cruciate ligament recontruction
- Trial name
- MONO-LCA (NCT07377669)
- Testing
- UKA + ACLr
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Anterior Cruciate Ligament Tear, Medial Collateral Ligament
A Study to Evaluate the Incrediwear Products Immediately After ACL Repair
To assess the benefits of using the Incrediwear knee products after ACL or ACL+MCL arthroscopic surgery, on the postoperative pain, range of motion and effusion.
- Trial name
- NCT06668376
- Testing
- Leg Sleeve
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Texas Bone and Joint
Sedentary Lifestyle, Knee Osteoarthritis
NEAT!2 Sedentary Behavior Reduction for Individuals With Past or Present Knee Symptoms, Injuries, or Surgeries
This study will evaluate the effectiveness of an mHealth sedentary reduction program over a 6-month period of time in adults with past or present knee symptoms, injuries, or surgeries.
- Conditions
- Sedentary Lifestyle, Knee Osteoarthritis, Knee Injuries, Knee Pain Chronic
- Trial name
- NCT03987932
- Testing
- NEAT!2, NEAT!2+Calls, Delayed NEAT!2
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
ACL Injury
Effects of HMB Supplementation on Recovery Following ACL Surgery
The anterior cruciate ligament (ACL) is a primary stabilizer of the knee, and thus when ACL injury occurs participation in physical activity is compromised.
- Trial name
- NCT02602561
- Testing
- HMB
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.
Pain, Postoperative
The Effect of Post-Surgery Exercise in Patients With Total Knee Replacement Surgery
postoperative pain; It is acute pain that begins with surgical trauma and decreases during tissue healing. Although it is predictable and treatable, it still seems to be an important problem today.
- Trial name
- NCT05331261
- Testing
- Total diz replacement ameliyatı
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Alev Keskin
Elective Surgery, Postoperative Cognitive Dysfunction
Effect Of Aspirin Preoperative on Postoperative Cognitive Dysfunction In Elderly Patients Undergoing Knee Arthroplasty
Studies have shown that the lifetime risk of developing symptomatic knee osteoarthritis is 40% in men and 47% in women; and the risk can be increased to 60% when the patient's BMI reaches 30 kg/m2.
- Conditions
- Elective Surgery, Postoperative Cognitive Dysfunction, Knee Arthroplasty
- Trial name
- NCT04225702
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Xuzhou Medical University
Knee Prosthesis
Effect of Normothermia Care Bundle in Knee Replacement Surgery
Osteoarthritis is a disease characterized by disruption of the integrity of articular cartilage as a result of erosion of articular cartilage.
- Trial name
- NCT06454877
- Testing
- active heating, pasive heating
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Periprosthetic Knee Infection
Outcome After Revisions of Infected Knee Arthroplasties
A prospective multicenter cohort study on all types of revision knee arthroplasty procedures performed due to infection.
- Trial name
- RIKA (NCT04427943)
- Testing
- revision surgery
- Where
- 8 sites in Denmark
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Pain, Spinal Surgeries, Hip and Knee Joint Replacement, Adverse Events
RAHM Foundation Retrospective Study of Various Diseases
This is a retrospective data collection on treatment of various disorders. This registry will include a variety of different products, implants, technologies and procedures.
- Trial name
- NCT02359786
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Rahm Foundation
Pain, Postoperative, Surgery
The Effect of Baduanjin on Patients Undergoing Knee Replacement Surgery
This randomized controlled trial aims to evaluate the effects of Baduanjin, a traditional Chinese mind-body exercise, on pain, comfort, and quality of recovery in patients undergoing total knee arthroplasty (TKA).
- Conditions
- Pain, Postoperative, Surgery, Knee Replacement, Nurse's Role
- Trial name
- NCT07109557
- Testing
- Baduanjin
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Niran Çoban
Postoperative Pain
Arthroplasty Inflammation Prophylaxis With Celecoxib
This double blinded, placebo controlled, study seeks to determine the efficacy of preoperative anti-inflammatory therapy on the reduction of postoperative pain in knee arthroplasty surgery.
- Trial name
- NCT00533247
- Testing
- Celecoxib
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zanbilowicz, Adam, DPM MS
Osteoarthritis, Sarcopenia
The Strong Brain Study
To evaluate operational aspects of studying pre to post surgery/hospitalization changes in the integrity of a major white matter pathways and how these contribute to reductions in the ability to produce forceful muscle…
- Trial name
- NCT02320864
- Testing
- Total knee replacement surgery
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Florida
Knee Arthritis
Internal Unicompartmental Arthroplasty After Tibial Valgization Osteotomy
This retrospective, monocentric study is about outcomes concerning patients who benefit from medial unicompartmental knee arthroplasty after previous high tibial osteotomy.
- Trial name
- ArOs (NCT06559592)
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Anesthesia Morbidity, Osteoarthritis, Knee
Evaluation of Anesthetic Techniques in Outpatient Total Joint Replacement Surgery in an Integrated Health Care Delivery System
The study is a retrospective cohort study of adult patients undergoing outpatient primary unilateral total knee or total hip replacement surgeries from 2017 to 2019 assessing for difference in anesthetic techniques and outcomes.
- Conditions
- Anesthesia Morbidity, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT04203732
- Testing
- Anesthesia Type
- Where
- United States
- Volunteers
- 12,466 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Osteo Arthritis Knee
Surgical Excision of the Fat Pad
Introduction: The infrapatellar fat pad (Hoffa's fat pad) is a structure which is located intra-articularly. Its function is not well known.
- Trial name
- NCT04503512
- Testing
- removal of fat pad, non removal of fat pad
- Where
- United Kingdom
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Spinal Anesthesia
Spinal Anesthetic for Hip and Knee Replacement Surgery - Intrathecal Morphine or Hydromorphone
In the current healthcare system, a short length of stay is paramount, for medical, functional, and financial reasons. Most patients undergoing hip and knee replacement at Hôpital Montfort institution receive spinal anesthetic…
- Trial name
- NCT04280939
- Testing
- spinal anesthesia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hopital Montfort