Clinical trials: Knee Surgeries, open to volunteers
Knee Osteoarthritis
SII Levels Following iPACK Block With Adductor Canal Block in Knee Arthroplasty
This randomized controlled trial evaluates the effect of ultrasound-guided iPACK block with Adductor Canal Block (ACB) on the Systemic Immune-Inflammation Index (SII) in elderly patients undergoing total hip arthroplasty under…
- Trial name
- NCT07449442
- Testing
- sodium Chloride, Ropivacaine Hydrocloride
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Prosthetic Joint Infection of Knee
Sola2 AMF Knee System Added to Surgery and Antibiotics in Adults With Knee Implant Infection
The goal of this clinical trial is to learn whether the Sola2 AMF Knee System, when added to surgery and antibiotic treatment, can safely improve outcomes, knee function, and quality of life in adults with knee implant infection.
- Trial name
- AMPLIFY (NCT07700927)
- Testing
- Intervention 1: Alternating Magnetic Field Treatment, Debridement, Antibiotics, Implant Retention
- Where
- 2 sites in United States
- Volunteers
- 165 people
- Sponsor
- Solenic Medical, Inc.
Hip Osteoarthritis, Hip Arthritis
Evaluating XPERIENCE™ Advanced Surgical Irrigation
A prospective, multi-center, double-arm, parallel, interventional, randomized, controlled clinical trial to assess the rate of periprosthetic joint infection (PJI) in patients undergoing primary total knee arthroplasty (TKA)…
- Conditions
- Hip Osteoarthritis, Hip Arthritis, Knee Osteoarthritis, Knee Arthritis
- Trial name
- XPERIENCE (NCT05543941)
- Testing
- XPERIENCE Advanced Surgical Irrigation, Dilute Betadine
- Where
- 8 sites in Canada
- Volunteers
- 7,600 people
- Sponsor
- Ottawa Hospital Research Institute
Aseptic Revision Knee Arthroplasty, Stiffness Following Revision Knee Arthroplasty
Does Joint Immobilization Following Revision Total Knee Arthroplasty Improve Range of Motion Following Surgery?
The goal of this study is to evaluate if knee immobilization for 10 days following revision total knee arthroplasty (rTKA) improves knee joint range of motion at 3 months postoperatively compared to standard of care postoperative…
- Trial name
- NCT07552415
- Testing
- Knee immobilizer, No Knee Immobilizer
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Hospital for Special Surgery, New York
Knee Osteoarthritis
Robotic Assisted Surgery In Total Knee Replacement
The goal of this clinical trial is to compare robotic arm assisted surgery with manual surgery in patients operated with knee replacement.
- Trial name
- NCT05842538
- Testing
- Triathlon
- Where
- 2 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Sahlgrenska University Hospital
Anesthesia, Surgery
Veterans Enhanced Recovery Using Integrative Treatments Around Surgery
The study aims to assess the implementation and effectiveness of Integrative Treatments - Music Medicine, Aromatherapy, and Battlefield Acupuncture - in the management of perioperative pain and anxiety, and in the reduction of…
- Conditions
- Anesthesia, Surgery, Knee Arthropathy
- Trial name
- VERITAS (NCT06333938)
- Testing
- Nonpharmacologic Treatment, Standard Care
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Durham VA Medical Center
Osteoarthritis, Knee, Osteoarthritis, Hip
Promoting Sleep to Alleviate Pain - Arthroplasty
PROSAP-A is a perioperative randomized, controlled trial with a 12-month follow-up period after total knee arthroplasty (TKA) or total hip arthroplasty (THA), aiming to investigate both acute and long-term postoperative effects…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Insomnia, Surgery
- Trial name
- PROSAP-A (NCT06145516)
- Testing
- Cognitive behavioral therapy for insomnia (CBT-I), Sleep education therapy (SET)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Uppsala University
Femur Fracture
Vastus Intermedius Dry Needling for Knee Stiffness Resulted From Surgically Managed Femoral Fractures With Open Reduction & Internal Fixation.
Orthopedic traumatic injuries are considered a major health epidemic, challenged by high morbidity, mortality, and socioeconomic burden.
- Trial name
- NCT06307587
- Testing
- dry needling
- Volunteers
- 44 people
- Sponsor
- Al-Razi Hospital
Knee Arthropathy
Virtual Rehabilitation Platform for Patients With Knee Prothesis
This clinical trial aims to evaluate the effectiveness and usability of the Trak Rehabilitation Platform in patients who have undergone knee replacement surgery.
- Trial name
- NCT06720779
- Testing
- TRAK physio knee prosthesis protocol, Knee conventional rehabilitation program
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Trak Health Solutions S.L.
Anesthesia
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block…
- Trial name
- EKAT-TeleTPS (NCT03747146)
- Testing
- Continuous Adductor Canal Catheter (ACC)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Postoperative Pain After Arthroscopic Knee Surgery
Adductor Canal Block Versus Parasartorial Compartment Block for Pain Relief and Recovery After Arthroscopic Knee Surgery
The goal of this clinical trial is to compare adductor canal block and parasartorial compartment block for pain relief and functional recovery in adults undergoing elective arthroscopic knee surgery.
- Trial name
- NCT07790393
- Testing
- Meperidine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Knee Arthroplasty, Total
The Effect of Tele-Consultation Supported Education After Total Knee Arthroplasty Surgery
Following total knee arthroplasty, patients may encounter numerous problems that can hinder the performance of daily living activities, negatively impact quality of life, and increase morbidity and mortality rates.
- Trial name
- NCT06784596
- Testing
- Teleconsulting supported training
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Turgut Sohret
Sport Surgery
Sport Surgery Products Outcomes - A Post-market Follow-up
Teknimed is currently conducting a post-market clinical follow-up which will confirm performance, safety and usability for all the Teknimed range of Sports products.
- Trial name
- NCT06532929
- Testing
- Orthopaedic surgeries (ankle), Orthopaedic surgeries (shoulder), Orthopaedic surgeries (knee)
- Where
- 10 sites in France
- Volunteers
- 390 people
- Sponsor
- Teknimed
Acute Postoperative Pain, Surgery
Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty
This is a single-center pilot study to determine if an adductor canal continuous nerve block is superior to single injection nerve block following total knee arthroplasty.
- Trial name
- NCT06784882
- Testing
- continuous peripheral nerve block with OnQ pump, single injection nerve block
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego
Arthroplasty, Replacement, Knee, Blood Loss, Surgical
Early Outcome of Simultaneous Bilateral Total Knee Replacement With and Without Tourniquet
This randomized controlled trial compared early outcomes after replacement of both knees during the same operation, with and without tourniquet use.
- Conditions
- Arthroplasty, Replacement, Knee, Blood Loss, Surgical, Pain, Postoperative
- Trial name
- NCT07905495
- Testing
- Simultaneous Bilateral Total Knee Replacement with Tourniquet, Simultaneous Bilateral Total Knee Replacement without Tourniquet
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Shifa International Hospital
Prosthesis-Related Infections
PCA Loading Time Before Knee Prosthetic Joint Infection Revision
Proof of principle pilot study of the effect of dietary nutritional loading of protocatechunic acid (PCA) on the health and welfare of individuals with prosthetic joint infection (PJI), as measured by standard biomarkers
- Trial name
- NCT06591728
- Testing
- Oral PCA
- Volunteers
- 10 people
- Sponsor
- Dr. Dean Reeves Clinic
Knee Injuries
Comparison Between the Use of the Tensioner and Standard Surgical Technique for Ligament Balancing of Total Knee Prostheses
the objective of the present study is to compare the post-operative laxity using stress radiographs and clinical scores in two groups of patients undergoing primary PS TKA with identical prosthetic model performed in two…
- Trial name
- NCT06770153
- Testing
- Tensor, standard
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis (Knee / Hip), Sarcopenia
Preoperative Muscle Stiffness, Functional Reserve, and Postoperative Quality of Recovery in Lower Extremity Arthroplasty
In elderly patients undergoing arthroplasty surgery, postoperative recovery quality is closely related to preoperative physical reserve. Sarcopenia and reduced muscle quality can increase postoperative complications.
- Conditions
- Osteoarthritis (Knee / Hip), Sarcopenia, Postoperative Recovery
- Trial name
- PRE-QoR (NCT07879209)
- Testing
- Handgrip Strength (HGS) Measurement, Ultrasound Shear Wave Elastography (SWE)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Etlik City Hospital
Patellofemoral Pain, PFP
A Study on the Effectiveness of Ankle Dorsiflexion Range of Motion Training in Patients With Patellofemoral Joint Pain.
Patellofemoral Pain (PFP) is a common knee condition causing pain around the kneecap during activities like running or squatting.
- Trial name
- NCT06958757
- Testing
- Standard Exercise Therapy + Ankle Dorsiflexion Training, Standard Exercise Therapy Only
- Volunteers
- 64 people
- Sponsor
- Tianjin University of Sport
Chronic Knee Pain, Obesity, Morbid
Photobiomodulation in Chronic Knee Pain in Patients Who Are in PreRehabilitation for Bariatric Surgery
Chronic pain is a global public health problem, which intensifies even more in the obese population, reaching about 33% of these patients.
- Trial name
- NCT05816798
- Testing
- Photobiomodulation, Standard Physiotherapy Tretament
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- University of Nove de Julho