Clinical trials: Labor, Obstetric
Preterm Birth, Prenatal Care Late
This Study Was to Investigate the Efficacy of Fetal Right Heart Doppler Findings in Determination of Pulmonary Maturity
Objective: The aim of this study was to investigate the efficacy of fetal right heart doppler findings in determination of pulmonary maturity.
- Conditions
- Preterm Birth, Prenatal Care Late, Preterm Labor
- Trial name
- NCT04296591
- Testing
- fetal heart doppler findings
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Pregnancy Preterm, Labor; Irregular
Multichannel EMG Diagnosing True Preterm Labor
We have designed new electromyography sensors for measuring uterine activity. These sensors are directional - they preferentially report uterine muscle contractions at specific locations, called regions.
- Conditions
- Pregnancy Preterm, Labor; Irregular, Preterm Labor
- Trial name
- PTL (NCT03785795)
- Testing
- Uncertain diagnosis of true labor
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- PreTeL, Inc
Obstetric Labor Complications, Staging of Placental Invasion
Ultrasound Staging in the Placenta Accreta
The investigators evaluated the efficacy of a staging system introduced by the American Institute of ultrasound in medicine 2015 including sonographic parameters associated with morbidly adherent placenta for antenatal prediction…
- Trial name
- NCT04253197
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Beni-Suef University
Obstetric Labor Complications, Hemorrhage
Thromboelastometry-guided Treatment Protocol Versus Standard Care of Major Haemorrhage in Obstetric Patients
This is a prospective, randomized and controlled study to find out if a rotational thromboelastometry(ROTEM) guided treatment protocol reduces the need for blood transfusions in major obstetric haemorrhage compared to standard…
- Trial name
- ROTEM-PPH (NCT02461251)
- Testing
- Rotational Thromboelastometry (ROTEM)
- Where
- Finland
- Volunteers
- 59 people
- Sponsor
- Tampere University Hospital
Vaginal Bleeding During Pregnancy
Tranexamic Acid in Pregnancies With Vaginal Bleeding
Tranexamic acid has been proposed and used for prevention and management of antepartum and postpartum hemorrhage.
- Trial name
- NCT03632824
- Testing
- Tranexamic Acid
- Where
- Iraq
- Volunteers
- 139 people
- Sponsor
- Hawler Medical University
Preterm Labor, Preterm Delivery
Two Methods of Diagnosing Preterm Labor
Use of modern diagnostic tools e.g. fetal fibronectin and ultrasound measurement of cervical length to diagnose preterm labor can result in improved outcomes compared to traditional diagnosis based on digital examination to…
- Trial name
- NCT01431885
- Testing
- Diagnosis by cervical length and fibronectin, Cervical change
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Preterm Labour
Detection of Preterm Labour by Cervical Length
Detection of short cervix by transvaginal ultrasound and its evidence based management to prevent preterm birth .
- Trial name
- NCT04104984
- Testing
- transvaginal ultrasound, Progesterone Vaginal Suppository, cervical cercalage
- Volunteers
- 966 people, healthy volunteers welcome
- Sponsor
- Assiut University
Obstetric Complication, Obstetric Labor Complications
ePartogram Effectiveness Study in Kenya
Quasi-experimental study to evaluate whether clinical care offered to clients was more appropriate and in line with WHO recommendations for care in normally progressing labor and in labor with complications, among providers using…
- Conditions
- Obstetric Complication, Obstetric Labor Complications, Newborn Morbidity
- Trial name
- NCT03757598
- Testing
- ePartogram use
- Where
- 12 sites in Kenya
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Labor Pain, Obstetric Pain
Association Between Bolus Rate and the Adequacy of Labor Analgesia Using Timed-intermittent Boluses
Administration of anesthetic solution into the epidural space is usually accomplished by a combination of continuous infusion, provider-administered boluses and patient-administered boluses (patient controlled epidural analgesia…
- Trial name
- NCT02340806
- Testing
- CADD-Solis pump (Smiths Medical)
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Preterm Birth, Preterm Labor
Effect of Supplementation of Fluoride on Maternal Periodontal Health, Preterm Delivery, and Perinatal Well-Being
The purpose of this study is to determine whether fluoride supplementation during pregnancy is effective in extending the length of gestation and improving overall perinatal well-being.
- Conditions
- Preterm Birth, Preterm Labor, Bacteremia, Preterm Premature Rupture of Fetal Membranes
- Trial name
- NCT02536352
- Testing
- Prenatal vitamin-mineral containing 3 mg fluoride, Prenatal vitamin-mineral containing 0 mg fluoride
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Preterm Labor
Study on Prevention, Treatment and Mechanism of Preterm Labor for Chinese Pregnant Women ≥35 Years Old
In China, there's no effective prevention and treatment on preterm birth for pregnant women ≥35 years old, so this study is necessary.
- Trial name
- NCT03210415
- Testing
- Observational Study Model
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Ministry of Science and Technology of the People´s Republic of China
Preterm Labor, Preterm Birth
Use of Placental Alpha Microglobulin-1(PAMG-1) to Diagnose Premature Rupture of Membranes in Pregnant Women
The study is to evaluate the accuracy of a test device called "PAMG-1" to see if a pregnant women has ruptured membranes in comparison to standardly used testing methods.
- Trial name
- PAMG-1 (NCT03715530)
- Testing
- PAMG-1 immunoassay
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Mark Santillan
Obstetric Labor Complications, Stillbirth
The PartoMa Project: For Improving Monitoring, Action and Triage During Labour
OVERALL OBJECTIVE In an East African referral hospital, to develop and analyze the effect of locally agreed and achievable guidelines and a continual in-house training program for strengthening partogram-based…
- Conditions
- Obstetric Labor Complications, Stillbirth, Maternal Death
- Trial name
- PartoMa (NCT02318420)
- Testing
- The PartoMa intervention
- Where
- Tanzania
- Volunteers
- 3,087 people
- Sponsor
- Ib Christian Bygbjerg
Labor, Premature
Correlation Between Vitamin D and B Regulatory Cell in Pregnancy
During pregnancy , the maternal immune system is always confronted with fetal alloantigens. the immunological mechanisms that prevent the rejection of the fetus are still not under understood.
- Trial name
- NCT04105881
- Testing
- Investigation
- Where
- 2 sites in Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Premature Labor
Performance of the Monica Novii Wireless Patch System in Threatened and Actual Pre-Term Labour
To study the equivalence of the Monica Novii™ Patch System in patients admitted for threatened pre-term labor and for pre-term labor \& delivery from 32 +0 weeks gestation by determining the equivalence of the Novii™ Patch System…
- Trial name
- NCT03223324
- Testing
- abdominal fetal/maternal monitor
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Monica Healthcare Ltd
Preterm Labor
Uterocervical Angle in Patients With Preterm Premature Rupture of the Membranes
To evaluate the performance of uterocervical angle (UCA) in the prediction of labor timing in patients with preterm premature rupture of the membranes
- Trial name
- NCT04095507
- Testing
- uterocervical angle
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nefise Nazlı YENIGUL
Labor Complication
Fetal Pillow Randomized Controlled Trial
The purpose of this study is to evaluate outcomes following cesarean delivery for failure to progress with the use of the Fetal Pillow.
- Trial name
- NCT03342508
- Testing
- Fetal Pillow
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Length of Pregnancy Prolongation in Hours
Antibiotics and the Prolongation of Pregnancy in Preterm Labor With an Advanced Cervical Exam
Preterm birth remains a major health concern affecting up to 12% of all live births prior to 37 weeks gestation. As preterm birth can often be associated with infection our proposal is to evaluate in a randomized fashion…
- Trial name
- NCT00589329
- Testing
- erythromycin and metronidazole (antibiotics)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Obstetric Complication, Vaginal Bleeding
Reliability of Simple Sonographic Findings Acquired With Hand-held Apparatuses to Inform Obstetric Diagnosis
the study aims to assess the reliability of ultrasound findings measured by hand held ultrasound probes used by operators with variable experience in a low resource hospital.
- Conditions
- Obstetric Complication, Vaginal Bleeding, Eclampsia Preeclampsia, Obstructed Labor
- Trial name
- NCT03856307
- Testing
- point of care ultrasound
- Where
- Sierra Leone
- Volunteers
- 300 people
- Sponsor
- Doctors with Africa - CUAMM
Preterm Labor
Uterocervical Angle in Idiopathic Polyhydramnios
To evaluate the performance of uterocervical angle (UCA) in the prediction of preterm labor in isolated polyhydramnios
- Trial name
- NCT03828695
- Testing
- uterocervical angle
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nefise Nazlı YENIGUL