Clinical trials: Labor
Preterm Birth, Short Cervical Length
The Impact of Vaginal and IM Progestins on the Cervix
The purpose of this study is to analyze how the body handles and responds to progesterone treatment in parous and nulliparous women at risk of pre-term birth.
- Trial name
- NCT01954095
- Where
- 4 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Term Delivery With Preterm Labor, Third Trimester, Term Delivery With Preterm Labor, Unspecified Trimester
Tidal Neonatal NO, Vitamins A and D, and Infant Lung Disease - The AD-ON Study
Children born prematurely are of greater risk of developing chronic lung disease (Bronchopulmonary Dysplasia). With an increase in the amount of premature children, we expect an increasing number of children with BPD.
- Conditions
- Term Delivery With Preterm Labor, Third Trimester, Term Delivery With Preterm Labor, Unspecified Trimester, Bronchopulmonary Dysplasia
- Trial name
- NCT01722760
- Testing
- measurements
- Where
- 2 sites in Denmark
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Stress, Burn Out
Effects of a Thermal Spa Short Residential Program for Prevention of Work-related Stress / Burn-out on Biomarkers of Stress - A Proof of Concept Study
Work-related stress is a public health issue. Among the multiple physical and psychological consequences of stress, increased mortality and cardiovascular morbidity seem the main concern.
- Conditions
- Stress, Burn Out, Heart Rate Variability
- Trial name
- ThermStress (NCT03536624)
- Testing
- 6 days spa residential program
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Mother-Child Relations, Preterm Birth
The 2015 Pelotas (Brazil) Birth Cohort Study
This is the fourth birth cohort to be carried out in the city of Pelotas (Brazil) including more than 4 thousand children followed-up since the pre-natal period to study maternal-child health.
- Conditions
- Mother-Child Relations, Preterm Birth, Infant Development, Breast Feeding
- Trial name
- NCT03271723
- Testing
- Observational study
- Where
- Brazil
- Volunteers
- 4,275 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Inflammatory Disease, Autoimmune Disease
Screening Protocol for Subjects Being Evaluated for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Protocols
Background: For every CHI research study, patients must fulfill a list of criteria, based primarily on their medical condition. To determine whether a patient meets these eligibility criteria to participate in a research…
- Conditions
- Inflammatory Disease, Autoimmune Disease, Immunologic Disease, Healthy Volunteers
- Trial name
- NCT00968084
- Where
- United States
- Volunteers
- 587 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
EOS, Pregnancy Related
Breech Pelvimetry by EOS® Technique With Change of Maternal Position and Delivery Route
When a patient presents with a fetus in PS after 36+0SA, after acceptance of participation in the study, pelvimetry with evaluation of the height of the fetal presentation by EOS® system in the upright and sitting position will…
- Conditions
- EOS, Pregnancy Related, Fetus Fetus, Breech Fetal Presentation
- Trial name
- PelviEOS (NCT05224908)
- Testing
- EOS
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
MDD
Can Mental Health Apps Work in the Real World? A Feasibility Pilot Study.
Over two million people in the US download health apps onto their smartphones and tablets, with the intent of improving their quality of life.
- Trial name
- NCT01808976
- Testing
- Problem Solving Therapy, Evolution, Basic health push app
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anxiety
Level of Anxiety Among Nurses Working in Psychiatric Settings
Anxiety is common among healthcare professionals, particularly nurses, who are faced with major responsibilities and stressful situations.
- Trial name
- Anxiété-IDE (NCT07418255)
- Testing
- data collection
- Where
- 2 sites in France
- Volunteers
- 543 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
Preeclampsia, Premature Birth
Cohort Study on the Levels of Placental Growth Factor and Nucleosomes in Early Pregnancy and Adverse Pregnancy Outcomes
Objective: This study aims to investigate the association between maternal serum placental growth factor (PLGF) and nucleosome levels in early pregnancy and adverse pregnancy outcomes, and to evaluate their predictive value for…
- Conditions
- Preeclampsia, Premature Birth, Fetal Growth Restriction, Recurrent Miscarriage
- Trial name
- NCT07841197
- Testing
- Measurement of plasma nucleosome and placental growth factor (PLGF) levels
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Sedentary Behavior, Motor Control Impairment
Lumbar Stabilization Exercises in Sedentary Adults
This pilot randomized controlled trial will examine the effects of a four-week lumbar spine stabilization exercise program on motor control, dynamic balance, and quality of life in healthy sedentary adults.
- Conditions
- Sedentary Behavior, Motor Control Impairment, Quality of Life
- Trial name
- NCT07447167
- Testing
- Ergonomic and Stretching Instructions, Lumbar Stabilization Exercise Program
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of West Attica
Physical Activity
Working on Wellness (WOW) Intervention
The main aim of this study is to measure the effectiveness of a worksite health promotion programme on improving physical activity behaviour and associated biological risk factors for cardiovascular disease among South African…
- Trial name
- WOW (NCT01494207)
- Testing
- Wellness counseling
- Where
- South Africa
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Stress, Position
The Effect of Positioning With Material and Hand-Face Maneuver
The study was administered in a randomized controlled experimental design to evaluate the effects of material positioning and hand-face maneuver on physiological parameters and stress symptoms in preterm newborns with gestational…
- Trial name
- NCT06136130
- Testing
- Tortoise Positioning Material Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Preterm Birth, Injuries
Nurse-Family Partnership Impact Evaluation in South Carolina
This study evaluates the effects of the Nurse Family Partnership (NFP), an established home-visiting program, using a scientifically rigorous individual-level randomized controlled trial.
- Conditions
- Preterm Birth, Injuries, Maternal Behavior
- Trial name
- NFP (NCT03360539)
- Testing
- Nurse-Family Partnership
- Where
- 9 sites in United States
- Volunteers
- 5,670 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Labor (Obstetrics)--Complications, Labor; Prolonged, First Stage
BUSCLAB - Buscopan to Prevent Slow Progress in Labor
To study the effect of Butylscopolamine Bromide on duration of the active phase of first stage of labor in first time mothers who cross the alert-line for labor dystocia, according to the WHO partograph.
- Trial name
- NCT03961165
- Testing
- Butylscopolamine Bromide 20 MG/ML, Sodium Chloride 9mg/mL
- Where
- Norway
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Poverty
Comprehensive Follow-up of Low Income Families. A Cluster-randomized Study
In a cluster-randomized design, the study evaluates the effectiveness of a skill- training program for social work professionals with the aim of improving the follow-up of low income families within Norwegian labor and welfare…
- Trial name
- CRCT-HOLF (NCT03102775)
- Testing
- Comprehensive follow-up program for low-income families, local family projects
- Where
- 29 sites in Norway
- Volunteers
- 884 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Pregnancy Preterm, Pregnancy Prom
Outpatient Antibiotics Following Previable Rupture of Membranes (pPPROM) Between 18 0/7 and 22 6/7 Weeks Gestational Age
A randomized, controlled, non-placebo trial to primarily assess the effect of oral, outpatient antibiotics (i.e., azithromycin and amoxicillin) on latency (i.e., proportion of patients that deliver within 28 days from membrane…
- Conditions
- Pregnancy Preterm, Pregnancy Prom, PROM, Preterm (Pregnancy), PROM (Pregnancy)
- Trial name
- NCT05345457
- Testing
- Azithromycin Pill, Amoxicillin Pill
- Where
- 3 sites in United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Premature Labor
Pharmacokinetics (PK) and Modeling of Betamethasone Therapy in Threatened Preterm Birth
Respiratory distress syndrome (RDS) is a life-threatening condition for premature neonates. Antenatal glucocorticoids have been used clinically in women with threatened preterm birth to accelerate lung maturation for more than 40…
- Trial name
- NCT02793700
- Where
- 2 sites in United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Indiana University
Post Partum Hemorrhage
Prophylactic Regimen of Intravenous Oxytocin, Intravenous Tranexamic Acid, and Intramuscular Ergot Derivative for Primary Prevention of Postpartum Hemorrhage in Intrapartum Cesarean Section Versus Intravenous Carbetocin Alone
While Carbetocin is effective in reducing PPH, the combination of oxytocin, Tranexamic acid, and Ergot derivatives may offer additional benefits in high-risk populations.
- Trial name
- NCT07318467
- Testing
- Intravenous Oxytocin, Intravenous Tranexamic Acid, and Intramuscular Ergot Derivative, Intravenous Carbetocin alone
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Diabetes
The Effects of Work Schedule and Sleep Patterns on Caregivers' Health
BACKGROUND. Sleep deficiency (not getting enough sleep) is widespread in American adults and can lead to many harmful health outcomes such as a higher risk of obesity, heart disease, and diabetes.
- Conditions
- Obesity, Diabetes, Cancer, Metabolic Syndrome
- Trial name
- NCT01443156
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Puerperal Sepsis, Postpartum Hemorrhage
Assessing Childbirth-related Complications at the Community Level in Kenya
Kenya is one of the countries in sub-Saharan Africa that still experience high maternal mortality. For instance, in 2008/09 maternal mortality ratio was estimated to be 488/100,000 live births.
- Conditions
- Puerperal Sepsis, Postpartum Hemorrhage, Preeclampsia and Eclampsia, Retained Placenta, Without Hemorrhage
- Trial name
- NCT01665456
- Where
- Kenya
- Volunteers
- 585 people, healthy volunteers welcome
- Sponsor
- Wilson Liambila
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