Clinical trials: Labor Complications
Prematurity, Framing
Framing and Decision Making in Neonatology
The purpose of this study is to study how people make decisions regarding delivery room management for infants born extremely premature when survival and long term outcomes are uncertain.
- Conditions
- Prematurity, Framing, Perinatal Decision Making
- Trial name
- NCT01421238
- Testing
- Survey
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Columbia University
Advanced Maternal Age Pregnancy, Premature
Pregnancies Outcomes in Advanced Maternal Age Women
Pregnancies occurring in advanced maternal age (AMA) have become more common over the last few decades for a variety of reasons.
- Conditions
- Advanced Maternal Age Pregnancy, Premature, Labor Complication, Delivery Complication
- Trial name
- POIAMA (NCT06528340)
- Testing
- spontaneous delivery
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centro di Ricerca Clinica Salentino
Preterm Labor, Preterm Birth
Use of Placental Alpha Microglobulin-1(PAMG-1) to Diagnose Premature Rupture of Membranes in Pregnant Women
The study is to evaluate the accuracy of a test device called "PAMG-1" to see if a pregnant women has ruptured membranes in comparison to standardly used testing methods.
- Trial name
- PAMG-1 (NCT03715530)
- Testing
- PAMG-1 immunoassay
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Mark Santillan
Infants, Premature, Breastfeeding
Effect and Experience of PreHomeCare of Preterm Infants Using Telecommunication and Smartphone Application
Background: Premature infants and their patents are discharged earlier from hospital and sent home in early in-homecare programs.
- Conditions
- Infants, Premature, Breastfeeding, Telecommunication, Patient Discharge
- Trial name
- NCT02581800
- Testing
- App group
- Where
- 4 sites in Denmark
- Volunteers
- 186 people
- Sponsor
- Mai-Britt Hägi-Pedersen
Premature
The Effect of Metaverse-Based Nursing Skills Laboratory
Depending on the education system, the increasing number of students, inadequate practice/skill laboratories, a small number of lecturers and students with limited time in the clinic have a negative impact on obtaining…
- Trial name
- NCT05706584
- Testing
- control grup (skills lab.) and experimental group (mateverse skill lab.)
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Medipol University
Premature Birth, Theory, Double Bind
The Meleis Theory on Postpartum Depression, Breastfeeding, and Maternal Self-Efficacy in Women Experiencing Preterm Birth
The aim of this study was to evaluate the effect of a nursing approach based on Meleis' Transition Theory on postpartum depression, maternal self-efficacy and breastfeeding self-efficacy in women who gave birth preterm.
- Conditions
- Premature Birth, Theory, Double Bind, Postpartum Depression, Breast Feeding
- Trial name
- NCT06250933
- Testing
- Postpartum Maternal Care and Premature Infant Care Training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Prelabor Rupture of Membranes, Premature Rupture of Membrane
Labor Induction With Misoprostol Versus Oxytocin in Women With Premature Rupture of Membranes
This study compares the rate of vaginal delivery after induction of labor with misoprostol versus oxytocin in women with prelabor rupture of membranes.
- Trial name
- NCT04143685
- Testing
- Misoprostol, Oxytocin
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- sammour.rami
Respiratory Distress Syndrome, Newborn, Premature Birth
Prophylactic Minimally Invasive Surfactant Evaluation
The purpose of this study is to explore the question: Does prophylactic administration of exogenous surfactant in the delivery room, using a minimally-invasive technique, improve outcome in preterm infants 22-29 weeks' gestation…
- Trial name
- PreProMISe (NCT06007547)
- Testing
- Poractant Alfa
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Placenta Accreta
Bilateral Internal Iliac Artery Ligation Before Cesarean Hysterectomy
All women with placenta accreta will be managed by upper segment cesarean section followed by cesarean hysterectomy without attempts of placental removal.
- Trial name
- NCT03129035
- Testing
- Cesarean hystrectomy, Internal iliac artery ligation
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
PREMATURITY
Skin-to-skin Contact to Promote Bacterial Decolonization in Preterm Infants
BACKGROUND Decolonization with topical antibiotics is necessary to prevent and / or control outbreaks of multidrug-resistant bacterial infection in the NICU (Neonatal Intensive Care Unit), but can trigger bacterial resistance.
- Trial name
- NCT01498133
- Testing
- skin-to skin contact
- Where
- Brazil
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Maranhão
Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary
Magnesium for Neonatal Neuroprotection and Mothers
Magnesium is a treatment for mothers to protect brains of babies born early. This study investigates combined effects of magnesium and spinal or epidural anesthesia on mothers having cesareans.
- Conditions
- Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary, Respiratory Depression
- Trial name
- MnMs (NCT01482078)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Bedrest, Premature Labor
Bed Rest for Threatened Preterm Labor. Pilot Study
The aim of the pilot trial is to assess at what extend women with arrested threatened preterm labor change their activity patterns at home in response to bed rest prescription.
- Trial name
- NCT00873314
- Testing
- Bed rest, Activity restriction
- Where
- Uruguay
- Volunteers
- 46 people
- Sponsor
- Institute for Clinical Effectiveness and Health Policy
Pregnancy Preterm, Neonatal Hypoglycemia
Continuous Glucose Monitoring of Late Preterm Birth After Corticosteroids
Women undergoing late preterm birth are at high risk of delivering a newborn with neonatal hypoglycemia. The investigators plan to monitor interstitial glucose levels prior to delivery in these women in order to develop a better…
- Conditions
- Pregnancy Preterm, Neonatal Hypoglycemia, Prematurity
- Trial name
- NCT03738293
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pediatrix
Placenta Accreta
3D Placental Volume in Placenta Accreta
Placenta Accreta spectrum is a major obstetric disease nowadays. Different methods are used for antenatal diagnosis. In our study, investigators are aiming to compare 2 common ways for diagnosis, i.e; 3D Ultrasound and 2D with…
- Trial name
- NCT06755047
- Testing
- 3D Ultrasound, 2D ultrasound
- Where
- Egypt
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cervical Insufficiency, Preterm Birth
Optimal Timing of Routine Cervical Length Measurements During Anatomy Survey
The goal of this clinical trial is to determine the optimal timing for measuring cervical length (CL) during fetal anatomy surveys in pregnant individuals.
- Conditions
- Cervical Insufficiency, Preterm Birth, Cervical Length Measurement
- Trial name
- NCT06822647
- Testing
- Cervical Length Measurement at the Beginning of the Anatomy Survey, Cervical Length Measurement at the End of the Anatomy Survey
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- Henry Ford Health System
Infant, Premature
Less Invasive Beractant Administration in Preterm Infants
The aim of this study is to assess the efficacy and feasibility of a new less invasive surfactant administration (LISA) technique with a specific designed cannula for surfactant administration using Beractant replacement in…
- Trial name
- NCT02611284
- Testing
- LISA, INSURE
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Premature Birth
NIRS Levels of Infants in Neonatal Intensive Care
Aim: This study was conducted to determine the effect of nursing care practices on the Near Infrared Spectroscopy (NIRS) levels of premature infants in the neonatal intensive care unit (NICU).
- Trial name
- NCT05246150
- Testing
- nursing care practices
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Placenta Accreta, Third Trimester
the Efficacy and Safety of the 3-steps Conservative Approach in the Management of Placenta Accreta Spectrum (a Novel Technique)
Placenta accrete spectrum (PAS) is an heterogeneous condition associated with a high maternal morbidity and mortality rate, presenting unique challenges in its diagnosis and management (Morlandoi et al., 2020).
- Trial name
- NCT05191316
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Obesity, Labor Complications
Labor Induction and Maternal BMI, Comparison of Different Pre-induction Cervical Ripening Methods
The purpose of this study is to investigate whether mechanical cervical ripening (using the Cook double balloon catheter) is superior or inferior to pharmacological agents (PGE1) in overweight and obese women undergoing labor…
- Trial name
- NCT02223949
- Testing
- Cook double balloon catheter, PGE1 tablet
- Where
- Israel
- Volunteers
- 624 people
- Sponsor
- Hillel Yaffe Medical Center
Labor, Premature, Preterm Premature Rupture of the Membranes
N-acetylcysteine in Intra-amniotic Infection/Inflammation
The aim of the study is to determine if N-acetylcysteine (a potent free radical scavenger) prevents the occurrence of adverse neonatal outcomes in preterm deliveries complicated by infection associated with preterm labor or…
- Conditions
- Labor, Premature, Preterm Premature Rupture of the Membranes, Infection, Inflammation
- Trial name
- NCT00397735
- Testing
- amniocentesis
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- Ohio State University
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