Clinical trials: Laboratory Procedure Development and Validation
Autism Spectrum Disorder, Developmental Delay
A Salivary miRNA Diagnostic Test for Autism
The goal of this study is to validate a panel of miRNAs that distinguish children with autism spectrum disorder (ASD) from their non-ASD peers with a positive MCHAT-R.
- Trial name
- NCT02832557
- Testing
- Salivary collection, Vineland Adaptive Behavior Scale-III Assessment, Medical history questionaire
- Where
- United States
- Volunteers
- 998 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Cancer
Development and Validation of Harbinger Health Test for Early Cancer Detection
This is a prospective, multi-center, observational study with a collection of biospecimens and clinical data from approximately 10,000 participants from up to 125 clinical network sites and locations in the United States.
- Trial name
- CORE-HH (NCT05435066)
- Testing
- Harbinger Health Test
- Where
- 128 sites in United States
- Volunteers
- 8,038 people, healthy volunteers welcome
- Sponsor
- Harbinger Health
Healthy Nurses, Educational Activities
The Study Focuses on Training Newly Employed Nurses With Two Groups Interventional (Simulation Training) & Control (Brochure) Group Using BLS -AHA 2020 Using Simulation, the Test Includes Pre-test & 2 Post-test Surveys to Assess Knowledge, Practice & Confidence Level.
The general objective of this study is to develop, validate and evaluate the effectiveness of simulation in basic life support training (SBLST) among newly employed nurses in Jordanian governmental hospitals; the study design is…
- Trial name
- BLS-NEN-HCP (NCT06001879)
- Testing
- Simulation in basic life support training (SBLST), standard treatment by using an AHA-BLS 2020 brochure
- Where
- Jordan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- yousef Shukry Mohammad Abu-Wardeh
Validation Study, Athletic Performance
Development of a Judo Specific Reactive Agility Test: a Reliability and Validity Study
Primary aim of this study is to develop a new reactive agility test spesific for Judokas and evaluate it's validity and reliability.
- Trial name
- NCT06663774
- Testing
- Physical Fitness Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Colorectal Carcinoma, Advanced Adenomas (AA)
Development and Validation of a Blood Test for Early Diagnosis of Colorectal Cancer
This is a prospective, multicenter, case-control study. The aim is to develop an optimized algorithm by combining the levels of molecular markers in plasma together with risk factors for developing colorectal cancer and clinical…
- Trial name
- ColoDix (NCT06889883)
- Where
- 9 sites in Spain
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- ADVANCED MARKER DISCOVERY S.L.
Healthy
Clock'N' Test: Development and Validation of a Test to Evaluate Emotional Disorders
This study concerns the validation of a clinical test that aims to reveal "first level" emotional disorders in neurological diseases.
- Trial name
- Clock'N'test (NCT03243370)
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Presbyopia, Refractive Errors
Development and Validation of an Internet-based Near and Intermediate-vision Reading Test
Primary objective of our study is to develop and validate an internet-based digital near and intermediate-vision reading test in the greek language.
- Conditions
- Presbyopia, Refractive Errors, Low Vision, Near Vision
- Trial name
- wDDART (NCT04618224)
- Testing
- DDART Testing, wDDART Testing
- Where
- 2 sites in Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Aminoglycoside Toxicity, Aminoglycoside-Induced Hearing Loss
Video Game Hearing Tests for Remote Monitoring of Ototoxicity
The reason for this clinical trial is to test different ways of carrying out hearing tests to be able to detect for hearing loss within the hospital and at home.
- Conditions
- Aminoglycoside Toxicity, Aminoglycoside-Induced Hearing Loss, Hearing Loss, Video Games
- Trial name
- VAROT (NCT05847556)
- Testing
- video game hearing tests, Audio-training
- Where
- 2 sites in United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Cancer
a PROspective Case Control Study to Develop and Validate a Blood Test FOr mUlti-caNcers Early Detection（PROFOUND）
This study is a multi-center, case-control study aiming at developing and blinded testing machine learning-based multiple cancers early detection model by prospectively collecting blood samples from newly diagnosed cancer…
- Trial name
- PROFOUND (NCT06217900)
- Where
- 8 sites in China
- Volunteers
- 16,666 people, healthy volunteers welcome
- Sponsor
- Shanghai Weihe Medical Laboratory Co., Ltd.
Gastroesophageal Reflux, Respiratory Aspiration
Cromolyn Detection of Silent Aspiration
The overall purpose of this project is to develop and validate a simple, non-invasive method to detect aspiration of gastro-intestinal fluid into the respiratory tract.
- Conditions
- Gastroesophageal Reflux, Respiratory Aspiration, Idiopathic Pulmonary Fibrosis, Lung Transplantation
- Trial name
- NCT01841307
- Testing
- Cromolyn Sodium
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Thoracic Cancer, Ovarian Cancer
Project CADENCE (CAncer Detected Early caN be CurEd)
With existing evidence showing the difference in miRNA expression levels between non-cancer and cancer groups, the investigators assume that levels of DNA methylation, RNA expression as well as protein concentration will also be…
- Conditions
- Thoracic Cancer, Ovarian Cancer, Liver Cancer, Prostate Cancer
- Trial name
- CADENCE (NCT05633342)
- Where
- Singapore
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- MiRXES Pte Ltd