Clinical trials: Labour
Cesarean Section
Misoprostol Versus Active Management of Labour in CS
Several treatment strategies are emplemented to prevent post delivery hemorage and decreasing maternal morbidity and mortality .
- Trial name
- NCT03390010
- Testing
- Misoprostol + syntocinon and using extra uterotonic drugs when needed ; methergine, Syntocinon and using extra uterotonic drugs when needed ; methergine carboprost
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Labor Pain
CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens
Analgesia in labour is not readily available in many parts of Sub-Saharan Africa. The overall cost of Epidural services in terms of human personnel and financial implication makes this inaccessible to many women in labour.
- Trial name
- SSS (NCT03117595)
- Testing
- Bupivacaine-fentanyl, Bupivacaine-fentanyl morphine
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Beckley
Labour Analgesia
Spinal Analgesia in Labour Pain
To evaluate the efficacy and safety of dexmedetomidine as an adjuvant to bupivacain and fentanyl in spinal Analgesia to decreases pain during normal labour
- Trial name
- NCT07332130
- Testing
- injecting dexmedetomidine, injecting mixture of bupivacaine fentanyl
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Minia University Hospital
Labor Pain
Response Patterns to the Electric Stimulation of Epidural Catheters in Term Pregnant Women
Lumbar epidural analgesia is commonly used for labor pain relief due to its effectiveness and safety. Despite its very high success rate, the epidural technique remains a rather blind technique and failures continue to occur.
- Trial name
- NCT02274467
- Testing
- Trans-catheter electric stimulation test
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Induction
Observatory on Artificial Labour-induction Methods and Measuring Immediate Postpartum Maternal Satisfaction
Our hypothesis is that there is one sequence of labour-induction that leads to a better experience of childbirth than others. This is based on the following underlying theories : Maternal satisfaction depends on the number of…
- Trial name
- SATISFACC (NCT04075630)
- Where
- 2 sites in France
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Labour Onset
Investigating the Physiology of Labour and Labour Onset Through Longitudinal Measurements Performed With a Wearable Sensor
The purpose of the study is to collect data to support the development and validation of a machine learning model for the automatic detection, prediction and monitoring of labour, through the use of a wearable sensor (Bloomlife…
- Trial name
- NCT03982654
- Testing
- Bloomlife
- Where
- 2 sites in Belgium
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Bloom Technologies
Birth, First, Labor Pain
Effects of Yoga and Meditation on The Birth Process
Introduction: Today it is seen that women lose their birthing strength, give the control to healthcare personnel during labour and the rate of c-section or interventional labour is increasing.
- Conditions
- Birth, First, Labor Pain, State Anxiety, Self Efficacy
- Trial name
- NCT04883541
- Testing
- yoga and meditation, Birth preparation training
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Primary Postpartum Haemorrhage
Comparative Study on the Effects of Sublingual Misoprostol in Addition to Standard AMTSL in Low Risk Parturients in LASUTH, Ikeja.
Postpartum haemorrhage is the leading cause of maternal haemorrhage globally. With active management of labour 3 to 16.5% of parturients still experience postpartum haemorrhage.
- Trial name
- NCT02424201
- Testing
- Misoprostol, vitamin c
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Lagos State University
Labour Pains, Massage
Effect of Nonpharmacological Methods on The Active Phase Of Labour
The aim of this clinical trial is to evaluate the effects of methods such as exercise and hot showers applied during the active phase of labour on labour pain, labour duration, mode of delivery, newborn health, and the labour…
- Conditions
- Labour Pains, Massage, Exercise
- Trial name
- EFPCMUAPLBO (NCT07060339)
- Testing
- Exercise Programme, Hot Shower Programme, Combined Application (Exercise + Hot Shower)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Labour Dystocia
Implementation of AFL Monitoring in Clinical Use
The overall objective of this randomized controlled trial is to develop a clinical standard procedure for measuring lactate in amniotic fluid (amniotic fluid lactate = = AFL) during childbirth before oxytocin stimulation is…
- Trial name
- NCT03650972
- Testing
- Samarin
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Parturition
The Effect of Foot Bath on Birth Pain and Birth Comfort
Although childbirth is seen as a natural, happy, meaningful and universal experience, women are often faced with severe pain, discomfort and a sensory state that can be overwhelming.
- Trial name
- NCT06380400
- Testing
- Foot bath
- Where
- Turkey (Türkiye)
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Birth Injuries
The Effect of Primary Delivery of the Anterior Compared With the Posterior Shoulder on Perineal Trauma: a Randomized Controlled Trial
It is unknown if primary delivery of the anterior or the posterior shoulder causes less perineal tear. The objective of this trial is to evaluate the incidence and degree of perineal trauma after primary delivery of the anterior…
- Trial name
- NCT01937546
- Testing
- Primary delivery of anterior shoulder, Primary delivery posterior shoulder
- Where
- Denmark
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Holbaek Sygehus
Preterm Birth
Atosiban Versus Placebo in the Treatment of Late Threatened Pre-term Birth
The aim of this study is to investigate if tocolysis with atosiban in late preterm birth (30 to 34 weeks) is (cost-) effective compared with placebo in improving neonatal morbidity and mortality.
- Trial name
- APOSTEL 8 (NCT05693688)
- Testing
- Atosiban
- Where
- Netherlands
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
First Pregnancy, Vaginal Delivery
Therapeutic Touch on Labour Pain, Anxiety and Childbirth Attitude
Introduction: Touching ensures physical, emotional and spiritual relaxation, confidence, peace, calmness and well-being, and increases self-esteem.
- Trial name
- touch (NCT04543487)
- Testing
- Therapeutic touch
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Neonatal Infection
Prevention of Bacterial Infections in Newborn
The last decade has witnessed an important reduction of the mortality in children under 5 years but such reduction has not impacted in neonates.
- Trial name
- PregnAnZI (NCT01800942)
- Where
- The Gambia
- Volunteers
- 829 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Blood Loss, Surgical
Ergot and Oxytocin During Cesarean Delivery Following Failure to Progress in Labour
Despite of marked improvements in clinical management, early postpartum hemorrhage(PPH)remains a significant contributor to maternal morbidity and mortality both in developing countries and in hospitals equipped with all that…
- Trial name
- NCT00481533
- Testing
- Methyl-Ergonovine-Oxytocin, Oxytocin
- Where
- Canada
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Parturition, Natural Childbirth
Effects of Aromatherapy on Childbirth
Aromatherapy is a form of complementary medicine that uses scented materials known as essential oils for the purpose of affecting a person's health or mood.
- Conditions
- Parturition, Natural Childbirth, Labor Pain
- Trial name
- NCT01051726
- Testing
- Aromatherapy oil, None essential oil
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Labor Long
Effect of Date Fruit Consumption in Later Pregnancy
EFFECT OF DATE FRUIT CONSUMPTION IN LATER PREGNANCY ON LENGTH OF GESTATION LABOR AND DELIVERY OF NULLIPAROUS WOMEN
- Trial name
- NCT05105893
- Testing
- Dates group
- Where
- Pakistan
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Pak Emirates Military Hospital
Labor Long, Labour;Obstructed
Biofeedback for Second Stage of Labor
The purpose of this study is to examine whether transperineal ultrasound as visual biofeedback can be used during labor as an effective tool for shortening the second stage of labor and reducing the need for instrumental…
- Trial name
- NCT04210908
- Testing
- Visual biofeedback
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Labour Pain
Spoken Animation for Labour Epidural
The purpose of this study is to evaluate a new animated information film as a tool for introducing the concept of epidural as a method of labour pain relief to expectant women.
- Trial name
- SALE (NCT07202221)
- Testing
- Participant views Epidural animation before reading gold standard written information, Participant receives current gold standard written information alone
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust