Clinical trials: Labour
Epidural, Analgesia
Epidural Analgesia and Delivery of Second Twin
Over an 8-year period, 124 twin pregnancies at gestational age ≥32 weeks with both twins presenting as a vertex and eligible for vaginal delivery were reviewed.
- Conditions
- Epidural, Analgesia, Labor Pain
- Trial name
- Epidural (NCT04608006)
- Testing
- Bupivacaine-fentanyl
- Where
- Egypt
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Abdelrady S Ibrahim, MD
Labor, Induced
Sublingual Misoprostol for Induction of Labor
The purpose of this study is to compare effectiveness and safety of a sublingual misoprostol 12,5 mcg with vaginal misoprostol 25 mcg for induction of labour with an alive and term fetus.
- Trial name
- SUBMISO (NCT01406392)
- Testing
- Misoprostol 25mcg, Sublingual Misoprostol
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Labor Complication, Labor Pain
Wide Use of Paperless Partograph in Evaluation of Labour
Paperless partograph wide using in labour room as simple tool in evaluation of labour
- Trial name
- labourRecord (NCT03276117)
- Where
- 6 sites in Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Labor Induction, Dinoprostone Vaginal Insert
Does Vaginal Washing Affect the Success Rate of the Labour Induction?
Investigators will use dinoprostone(Propess TM) for cervix ripening and labor induction in term pregnant women.Vaginal pH base is achieved with the effect of hormones in pregnancy and associated with this, vaginal infections…
- Conditions
- Labor Induction, Dinoprostone Vaginal Insert, Vaginal Infection, Effect Increased
- Trial name
- NCT03050684
- Testing
- vaginal lavage group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Obstetric Labour, Premature
A Two Cohort Study to Look at the Metabolites of GSK221149, the Metabolism of GSK221149 Administered With a High Fat Meal and With Ketoconazole
This is a two part study. Part A of the study will evaluate the metabolites of GSK221149 following single and repeat oral dosing and will also assess the pharmacokinetics of GSK221149 when administered with a potent CYP3A4…
- Trial name
- NCT01627587
- Testing
- GSK221149 750 mg, Ketoconazole, GSK221149 100 mg
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Delivery, Obstetric, Cesarean Section
Comparison Between Two Medical Devices for Labor Induction After Previous C-section
The objective of the study ist to compare the Dilapan-S and the Cook Ballon device for the mechanical induction of labour in women with a previous C-section.
- Conditions
- Delivery, Obstetric, Cesarean Section, Obstetric Delivery
- Trial name
- DiBal (NCT06506721)
- Testing
- Double ballon device, Cook, Hygroscopic cervix dilators, Dilapan-S
- Where
- Switzerland
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Therapeutic Touch, Childbirth
Effect of Therapeutic Touch on Labor Pain and Hormone Levels
This study was conducted to determine the effect of sacral region-focused therapeutic touch applied during the latent phase of labour on hormone levels, labour comfort, and perception.
- Trial name
- NCT05179915
- Testing
- Therapeutic Touch focused on sacral region
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cukurova University
RSV Infections, RSV Immunisation
A Clinical Trial on Safety in Pregnant Women and How Well the Infant is Protected Against RSV-associated Lower Respiratory Tract Infection When the Pregnant Woman Receives the Approved RSV Vaccine Compared to a Placebo.
Respiratory syncytial virus (RSV) is a virus that often affects children during childhood. Even though most cases of RSV are mild, it can cause serious disease and even death - especially in very young babies, babies born too…
- Conditions
- RSV Infections, RSV Immunisation, Preterm Labour
- Trial name
- NCT06955728
- Testing
- Vaccine
- Where
- 11 sites in Ghana, Kenya and 2 more
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- University of Witwatersrand, South Africa
Gestational Diabetes, Hypoglycemia, Neonatal
Glucose Control During Labour in Gestational Diabetes Mellitus With Insulin Treatment: A Randomized Controlled Trial
Pregnant women with gestational diabetes who are treated with insulin and their daily insulin dose is 30 IU or more will be randomized into two groups. Active treatment group will receive insulin-glucose-infusion during labour.
- Trial name
- NCT02590016
- Testing
- Insulin, Aspart
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Obesity
Ultrasound Imaging For Facilitating Labour Epidurals in Obese Parturients
The efficacy of an epidural depends mainly on accurate placement of the catheter in the epidural space. Therefore, identification of the epidural space is the most vital part of the procedure.
- Trial name
- NCT00439998
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Medical Education, Normal Vaginal Delivery
Virtual Reality Birth Simulator
The investigators compared an in-house developed virtual reality simulator for normal vaginal deliveries with a legacy mannequin-based simulation in a cluster randomised study involving Year 4 medical students undergoing their…
- Conditions
- Medical Education, Normal Vaginal Delivery, Simulation Training, Virtual Reality
- Trial name
- ViVaDeX (NCT06653270)
- Testing
- Virtual reality simulator, Mannequin-based simulator
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Intrapartum Fetal Monitoring
WHO Labor Care Guide for Obstetric Care Providers in Public Health Facilities in Mbarara, Southwestern Uganda
The goal of this mixed method multisite effectiveness-implementation study across all basic and comprehensive emergency obstetric and newborn care facilities in Mbarara district and Mbarara City in Southwestern Uganda is to…
- Trial name
- NCT05979194
- Testing
- Labor Care Guide
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Mbarara University of Science and Technology
Labour Pain, Cold Therapy
Effect of Intermittent Heat and Cold Therapy on Comfort During Labor
Summary of the Study Childbirth is one of the most significant and complex experiences in any mother's life. According to a study, labour pain ranges from mild to severe and is felt throughout the body, particularly in the lower…
- Conditions
- Labour Pain, Cold Therapy, Heat Therapy
- Trial name
- NCT06214585
- Testing
- Intermittent heat and cold versus heat-only therapy, Heat- only Therapy
- Where
- Nepal
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University, Nepal
Duration of Labour
Metoclopramide Versus Hyoscine Butylbromide in Shortening Duration of First Stage of Labour
BACKGROUND Prolonged labour can lead to increased maternal and neonatal mortality and morbidity. The risk for complications of prolonged labour is more in poor resource settings.
- Trial name
- NCT05222646
- Testing
- Metoclopramide
- Where
- Nigeria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Uwakwe Emmanuel Chijioke
Premature Obstetric Labor
Progesterone and Aminophylline for the Prevention of Preterm Labour
The aim of this study is to investigate whether the combination of aminophylline and Progesterone (P4) is acceptable to women at high-risk of Pre-term labour (PTL).
- Trial name
- PROGRAM (NCT03152942)
- Testing
- Progesterone, Aminophylline
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- St Stephens Aids Trust
Pre-Eclampsia
qMOLI- A Qualitative Assessment of Misoprostol or Oxytocin for Labour Induction
Q MOLI is an alongside qualitative study, for the 'Misoprostol or Oxytocin for Labour Induction' (MOLI) pragmatic, open-label, randomised controlled trial, comparing a misoprostol/misoprostol regime vs the standard…
- Trial name
- qMOLI (NCT04037683)
- Testing
- Misoprostol Oral Tablet, Oxytocin
- Where
- India
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Anesthesia, Obstetrical, Analgesia, Epidural
Epidural Analgesia During Labour
Randomized single blind trial based on comparing the way the local anesthetic is dosificated during labour. The pain control is evaluated and compared with both dosage techniques (PCEA vs PIEB)using levobupivacaine and fentanyl.
- Trial name
- PIEBvsPCEA (NCT03133091)
- Testing
- PIEB: Patient Intermittent Epidural Boluses, PCEA: Patient Controlled Epidural Analgesia
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital del Rio Hortega
Prolonged Pregnancy, Sleep Disturbance
Sleep and Depression in Induction of Labour
Randomised trial comparing double balloon catheter for induction of labor between inpatient and outpatient groups. The investigators assess how sleep disturbances and depression of the mother affect to the pain during balloon…
- Conditions
- Prolonged Pregnancy, Sleep Disturbance, Depression
- Trial name
- NCT03380897
- Testing
- Intervention for outpatient group was to go home, Intervention for inpatient group was to stay at ward
- Where
- Finland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Pain
Tsui Test as a Predictor of Bupivacaine Consumption in Labour Epidurals
Low current electrical stimulation test, also called the Tsui test, has been used successfully to confirm the catheter location in the epidural space in various patient populations.
- Trial name
- NCT00792311
- Testing
- Tsui test
- Where
- Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labour
Pain Management at Latent Period of Labour
Examine the effectiveness of an analgesic in PERFALGAN maternity latent phase of labor. Examine the safety in PERFALGAN in the mother and the newborn in terms of the level of drug in blood
- Trial name
- NCT03105830
- Testing
- iv paracetamol
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya