Clinical trials: Labour Induction
Labor Induction, Cervical Ripening
Trial of Foley Catheter With and Without Extra-Amniotic Saline Infusion for Labor Induction
The purpose of this study is to compare the efficacy of a transcervical Foley catheter with and without extra-amniotic saline infusion (EASI) for priming the cervix for labor.
- Trial name
- FOLEYEASI (NCT00442663)
- Testing
- Transcervical Foley Catheter, Transcervical Foley Catheter with an EASI
- Where
- 4 sites in United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Induction of Labor Affected Fetus / Newborn, Cervical Ripening
Patient Satisfaction During Outpatient Versus Inpatient Foley Catheter Induction of Labor
Labor induction is one of the most common obstetric procedures performed in the U.S. In 2012, the last year for which data is available, 23.7% of all deliveries were the result of inductions.
- Conditions
- Induction of Labor Affected Fetus / Newborn, Cervical Ripening, Patient Satisfaction
- Trial name
- NCT02975167
- Testing
- Outpatient Cervical Ripening, Inpatient Cervical Ripening, Foley catheter placement
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Labor (Obstetrics)--Complications
Uterocervical Angle Versus Cervical Length as a Predictor of Labor Induction in Term Singleton Pregnancy
Induction of labor is frequently performed in all obstetric clinics. Failed IOL has been defined in many different ways.Bishop scoring, which is a traditional and subjective method, is more frequently evaluated with cervical…
- Trial name
- NCT06558500
- Testing
- Uterocervical angle
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Normal Vaginal Delivery
Oral Misoprostol Solution in Comparison to Vaginal Misoprostol in Induction of Labor
Induction of labour at term is a common obstetric intervention. Induction of labour is the artificial initiation of labour before its spontaneous onset for the purpose of delivery of the fetoplacental unit using mechanical or…
- Trial name
- NCT03863392
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Gestational Diabetes, Pre-Eclampsia
Body Fat Index for Obstetric Risk Stratification
Primary Outcome:- GDM Diagnosis Secondary Outcomes:- Pre-eclampsia diagnosis. Cesarean section delivery due to labor dystocia defined as protracted or arrested progress of labor using labor partogram.
- Conditions
- Gestational Diabetes, Pre-Eclampsia, Labour Dystocia
- Trial name
- BFIors (NCT05533996)
- Testing
- ultrasound
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pregnancy, Obesity
When to INDuce for OverWeight? (WINDOW)
The rate of overweight and obese women becoming pregnant is increasing. Obesity in pregnancy along with delivery by cesarean section in obese women is associated with several complications as compared to normal weight women.
- Conditions
- Pregnancy, Obesity, Parturition
- Trial name
- WINDOW (NCT04603859)
- Testing
- Elective induction of labor at 39 gestational weeks and 0 to 3 days
- Where
- 12 sites in Denmark
- Volunteers
- 1,901 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cervical Ripening, Unfavorable Cervix
Oxytocin vs Prostaglandins for Labor Induction of Women With an Unfavorable Cervix After 24h of Cervical Ripening
Twenty-two percent of deliveries in France are induced. In cases where labor is induced and cervix is unfavorable, cervical ripening prior oxytocin administration is advised in order to reduce the risk of cesarean delivery.
- Trial name
- OPIC (NCT04949633)
- Testing
- Prostaglandins, Oxytocin
- Where
- 14 sites in France
- Volunteers
- 1,494 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Induction of Labor, Previous Cesarean Section
Labor Induction After Cesarean Section: Outcome, Hormonal Trends
Objectives- To compare changes in labour-associated maternal and fetal hormone levels during breast stimulation, balloon induction and spontaneous labour.
- Conditions
- Induction of Labor, Previous Cesarean Section, Hormonal Changes
- Trial name
- NCT04244747
- Testing
- induction of labor by breast stimulation, induction of labor by catheter balloon
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Induction of Labor Affected Fetus / Newborn
A Comparison Between the Effect of Oxytocin Only and Oxytocin Plus Propranolol on Induction of Labor in Term Pregnancy
The present study is conducted to compare the effect of Oral Propranolol and Oxytocin, versus Oxytocin only on induction of labor in term pregnancy.
- Trial name
- NCT03533699
- Testing
- Propranolol
- Where
- Egypt
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Intrapartum Fetal Monitoring, Pregnancy
Feasibility and Acceptability of the Combination of Propess and AN24 Monica for Outpatient Labour Induction (PRAM)
In order to confirm the feasibility of home monitoring with Monica AN 24, a licensed portable device for measuring fetal and maternal electrocardiogram (ECG), and the feasibility of inpatient monitoring with Monica AN 24 in…
- Trial name
- PRAM (NCT01026948)
- Testing
- Dinoprostone, Monica AN 24
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Liverpool Women's NHS Foundation Trust
Cervical Ripening, Induction of Labor
Heated Saline in Cervical Balloon for Labor Induction, a RCT
This study is a single-center, randomized, two-arm, controlled trial, including women requiring cervical ripening during the process Induction of Labor using Balloon catheter (BC).
- Conditions
- Cervical Ripening, Induction of Labor, Unfavorable Cervix, Mechanical Method
- Trial name
- NCT05864326
- Testing
- Warm group, Room temperature group
- Where
- Switzerland
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Begona Martinez de Tejada
Induction of Labor
Stepwise Labor Induction Following Failure of Prostaglandin Vaginal Insert for Labor Induction
Induction of labor is one of the most common obstetrical medical procedures performed today. Iatrogenic stimulation of uterine contractions prior to the onset of spontaneous labor is undertaken for various maternal and fetal…
- Trial name
- NCT02684305
- Testing
- Administration of Propess, balloon, Intravenous oxytocin infusion
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Induced; Birth, Labor Onset and Length Abnormalities
Papaverine and Oxytocin vs Oxytocin Alone in Labor Induction
This study aims to evaluate the efficacy and safety of combining papaverine with oxytocin for labor induction compared to oxytocin alone
- Trial name
- NCT06547437
- Testing
- Papaverine, normal saline
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Oligohydramnios
Active Induction of Labor in Pregnancies Complicated With Oligohydramnios at Term
The purpose of this study is to evaluate the risk of cesarean delivery in pregnancies complicated with isolated oligohydramnios managed by induction of labor.
- Trial name
- NCT02581774
- Testing
- normal delivery tracking
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Induction of Labor Affected Fetus / Newborn
The Use of D5LR Versus LR for Induction of Labor and Time to Delivery in Multiparous and Primiparous Patient's With Favorable and Unfavorable Bishop's Scores
Currently, the optimum IV fluid for induction of labor is unknown. The goal of this study is to determine the optimum fluid for induction of labor, D5LR versus LR.
- Trial name
- NCT03822052
- Testing
- Lactated ringers, 5% dextrose lactated ringers
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Infections
Azithromycin Before Induction
This is a double blinded randomized control trial involving administration of 2 grams prophylactic azithromycin in third trimester patients undergoing induction of labor at our institution to demonstrate reduction in maternal and…
- Trial name
- NCT06543290
- Testing
- Azithromycin Pill
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Arrowhead Regional Medical Center
Failed Induction of Labor
A Novel Protocol for Labour Induction
The use of foley catheter was tested many times and proved to be effective for induction of labour.
- Trial name
- NCT01506388
- Testing
- foley catheter, Misoprostol, Vaginal IMN
- Where
- 2 sites in Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain
Preventive Analgesia in Multiparas Undergoing Induction of Labour
Our study is about providing a better birthing experience by placing and initiating epidural for labour pain before the contractions start.
- Trial name
- NCT00465231
- Testing
- bupivacaine, fentanyl, preservative free saline
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Castor Oil, Prolonged Pregnancy
Effectiveness of Castor Oil in Preventing Formal Induction of Labour in a Tertiary Institution
This study demonstrated that castor oil was effective in reducing the need for formal induction of labour and the administration-delivery interval with minimal maternal side-effects, at an initial dose of 30ml and single repeat…
- Trial name
- NCT06841939
- Testing
- castor oil, Water
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assumpta Nnenna Nweke
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Labor for Induction Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women scheduled for an induction of labor, with whom analgesia is maintained with a combined spinal…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982851
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Northwestern University