Clinical trials: Labour Induction
Failed Induction, Cervical Dystocia
Transvaginal Sonographic Measurement of Cervical Length Versus Bishop Score in Induction of Labour for Prediction of Caesarean Delivery.
Transvaginal sonographic measurement of cervical length versus Bishop score in labour induction at term for prediction of Caesarean delivery. This study is prospective study.
- Trial name
- NCT03430804
- Testing
- Bishop score calculation of modified Bishop score in numbers by digital vaginal examination
- Where
- Egypt
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obesity, Induced; Birth
Effect of Maternal Obesity on Labour Induction in Postdate Pregnancy
This study investigate the progression of labour in 144 normal weight pregnant women (BMI <30) and 144 obese pregnant women (BMI >30) , not in labor admitted for induction of labor.
- Trial name
- NCT02788305
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Induction of Labour, Labour, Induced
Misoprostol Labour Induction Study
Labour induction is a frequent obstetric intervention (~20%). Prostaglandins (PGs) are effective agents, but gastrointestinal (GI) intolerance has limited use to non-oral routes.
- Trial name
- NCT03489928
- Testing
- Oral Misoprostol, Vaginal Misoprostol, Dinoprostone
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- David Young
Induction of Labor
Dilapan-S Versus Double Balloon Catheter (CRB) for Preinduction of Labor at Term
Induction of labor (IOL) is a frequently performed procedure in obstetrics, aimed to achieve vaginal delivery when continuing the pregnancy is no longer advisable.
- Trial name
- NCT07010653
- Testing
- Higroscopic Cervical ripening, Cervical ripening via CRB
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Cervical Ripening
Induction of Labor in Oligohydramnios
When oligohydramnion - decreased amniotic fluid, is diagnosed at term pregnancies, the common practice is to induce labor. Whenever the cervix is not ripened, there are several methods to ripen the cervix, two of which are…
- Trial name
- NCT00815542
- Testing
- double balloon catheter, prostaglandins E2
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Preeclampsia, Intrauterine Growth Restriction
sFlt1/PlGF and Planned Delivery to Prevent Preeclampsia at Term.
Preeclampsia (PE) affects ~5% of pregnancies. Although improved obstetrical care has significantly diminished associated maternal mortality, PE remains a leading cause of maternal morbidity and mortality in the world.
- Conditions
- Preeclampsia, Intrauterine Growth Restriction, Maternal Hypertension, Neonatal Outcome
- Trial name
- PE37 (NCT04766866)
- Testing
- sFlt1/PlGF screening in maternal blood at 35 to 36.6 weeks of gestation
- Where
- 21 sites in Belgium, Colombia and 7 more
- Volunteers
- 9,132 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Previous; Cesarean Section, Cicatricial, Complicating Pregnancy or Childbirth, Affecting Fetus or Newborn, Prelabor Rupture of Membranes
Balloon Induction of Labor in PROM for TOLAC
A prospective randomized controlled trial to evaluate the safety and efficacy of labor induction with a double balloon catheter (Atad Ripener Device) in women desiring TOLAC (trial of labor after cesarean) with PROM (pre labor…
- Trial name
- BILROM-TOLAC (NCT03399266)
- Testing
- Double Balloon catheter for induction of labor
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Prelabor Rupture of Membranes, Premature Rupture of Membrane
Labor Induction With Misoprostol Versus Oxytocin in Women With Premature Rupture of Membranes
This study compares the rate of vaginal delivery after induction of labor with misoprostol versus oxytocin in women with prelabor rupture of membranes.
- Trial name
- NCT04143685
- Testing
- Misoprostol, Oxytocin
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- sammour.rami
Second Trimester Labor Induction
Second Trimester Labor Induction
A superior second trimester medical abortion regimen has not been identified. Studies suggest that a regimen of mifepristone and misoprostol given 36 to 48 hours apart has the shortest median induction-to-abortion interval…
- Trial name
- NCT00592215
- Testing
- Experimental (mifepristone and misoprostol)
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Fetus or Newborn or Maternal; Effects of Induction of Labor
Tearing of Membranes Before Birth - a Comparison Between Two Ways of Induction of Labor Pitocin Opposite Prostaglandin
Premature rupture of membranes (PROM) is a common occurrence that occurs in the incidence of 8-10% of births. Since the duration until delivery is important in avoiding the risk of complications, several studies have been…
- Trial name
- NCT02720978
- Testing
- Intravenous oxytocin, vaginal prostaglandin
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Labor Onset and Length Abnormalities, First Birth
Use of Cinnamomum Verum for Induction of Labor. Double Blind Randomized Clinical Trial
The purpose of the research protocol is to evaluate the effectiveness of Cinnamomum verum extract for the initiation of labor. Cinnamaldehyde ((E)-3-Phenylprop-2-enal) is an α, β unsaturated aromatic aldehyde, derived from…
- Trial name
- CINNALAB (NCT06164613)
- Testing
- Cinnamomum Verum oil extract
- Where
- Honduras
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Induced Vaginal Delivery
Potential of Vojta's Reflex Locomotion as a Pre/Induction Method for Uterine Activity: a Pilot Study
The Vojta's method is neurophysiological rehabilitation method used to support and induce reflex responses of locomotor and vegetative system.
- Trial name
- NCT06339528
- Testing
- Vojta's Reflex Locomotion
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Induction of Labor Affected Fetus / Newborn
Vaginal Misoprostol and Foley Catheter for Induction of Labor
to compare between sequential and concurrent use of vaginal misopristol plus foleys catheter for induction of labor
- Trial name
- NCT02952807
- Testing
- Misoprostol, Foley Catheter
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Induction of Labor
Cervical Ripening Balloon for 12 Hours vs. 1 Hour.
The aim of this study is a comparison of induction of labor with a cervical ripening balloon left in place for one hour compared to twelve hours. The primary outcome is time to delivery.
- Trial name
- NCT05922111
- Testing
- cervical ripening balloon for one hour, cervical ripening balloon for twelve hours
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Labor, Induced, Amniotomy
Early Versus Late Amniotomy During Labor Induction in Women With Bishop's Score of ≥ 6
Labor induction is the stimulation of uterine contractions during pregnancy, before labor begins on its own to achieve a vaginal birth.
- Trial name
- NCT04731896
- Testing
- Amniotomy
- Where
- Tunisia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Obstetric Labour, Premature
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Retosiban (GSK221149) When Dosed With Efavirenz (EFZ)
This will be a randomized single sequence open label study. This study is designed to determine if chronic dosing with efavirenz (EFZ) will have an effect on the pharmacokinetics (PK) of intravenously-administered retosiban in…
- Trial name
- NCT01867996
- Testing
- Retosiban, EFZ 600 mg
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Normal Vaginal Delivery
Oral Misoprostol Solution in Comparison to Vaginal Misoprostol in Induction of Labor
Induction of labour at term is a common obstetric intervention. Induction of labour is the artificial initiation of labour before its spontaneous onset for the purpose of delivery of the fetoplacental unit using mechanical or…
- Trial name
- NCT03863392
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Induction of Labour
To Study the Efficacy and Safety of Misoprostol by Sublingual Routes for Induction of Labour
This research is to compare the efficacy and the safety of sublingual misoprostol with vaginal misoprostol administration for the induction of labour for primigravida at 41 or more weeks of pregnancy.
- Trial name
- SL-IOL (NCT04887493)
- Testing
- Misoprostol
- Where
- Bhutan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bhutan
Induction of Labor Affected Fetus / Newborn
A Comparison Between the Effect of Oxytocin Only and Oxytocin Plus Propranolol on Induction of Labor in Term Pregnancy
The present study is conducted to compare the effect of Oral Propranolol and Oxytocin, versus Oxytocin only on induction of labor in term pregnancy.
- Trial name
- NCT03533699
- Testing
- Propranolol
- Where
- Egypt
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Oxytocin, Labor Pain
The Stimulation To Induce Mothers Study
The investigators propose a parallel group randomized clinical trial of intrapartum nipple stimulation versus exogenous oxytocin infusion for nulliparous women undergoing induction of labor near term.
- Conditions
- Oxytocin, Labor Pain, Induction of Labor Affected Fetus / Newborn, Physiologic Effects of Drugs
- Trial name
- STIM (NCT05079841)
- Testing
- Electric breast pump, Exogenous oxytocin intravenous infusion without nipple stimulation.
- Where
- 3 sites in United States
- Volunteers
- 933 people, healthy volunteers welcome
- Sponsor
- Yale University