Clinical trials: Labour Induction
Induction of Labor Affected Fetus / Newborn
A Trial of Cervidil for Outpatient Pre-induction of Cervical Ripening
Induction of labor is a frequently planned obstetric procedure. Induction for women with an unfavorable cervix (bishop score <6) increases the risk of cesarean section.
- Trial name
- NCT03806231
- Testing
- Outpatient Dinoprostone 10mg, Inpatient Dinoprostone 10 mg
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Induction of Labour
Effectiveness and Safety of Induction of Labour Using a Double Balloon Catheter (INDOBA)
The goal of induction of labor is to achieve vaginal delivery by stimulating uterine contractions before the spontaneous onset of labor.
- Trial name
- INDOBA (NCT04163744)
- Testing
- Double balloon catheter
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Labor Onset and Length Abnormalities, Induced; Birth
Comparison of Misoprostol Ripening Efficacy With Dilapan
The purpose of this study is to find out if Dilapan works as well as Misoprostol for preparing the mouth of the uterus (cervix) for inducing labor in women who need to undergo this procedure.
- Trial name
- COMRED (NCT03670836)
- Testing
- Dilapan, Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Columbia University
Pregnancy Outcome
Foley Balloon Study for Cervical Ripening - Cost Comparison Between Outpatient and Inpatient Cervical Ripening
The objective of this study is to determine the impact of outpatient cervical ripening with transcervical balloon placement for induction of labor at term on the length and cost of inpatient hospitalization when compared to…
- Trial name
- Balloon (NCT05506631)
- Testing
- Outpatient Foley balloon placement, Inpatient Foley Balloon placement
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Lehigh Valley Hospital
Vaginal Delivery, Labor
Labor Protocol Study
The goal of this study is to see if there is a better way to induce labor.
- Conditions
- Vaginal Delivery, Labor, Induced; Birth
- Trial name
- NCT04004845
- Testing
- Cytotec, oxytocin, Cervical Foley Balloon
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Prelabour Rupture of Membranes at Term
A Pilot RCT on the Management of Term Prelabour Rupture of Membranes
This is a pilot study that will eventually result in a main randomised controlled trial that will look at what management is associated with a higher rate of normal birth and a lower rate of chorioamnionitis (maternal infection)…
- Trial name
- NCT02872883
- Testing
- Expectant management, Minimal Vaginal examinations (only when necessary), Active management
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Central Lancashire
Induction of Labor
Intravaginal Isosorbide Mononitrate in Addition to Misoprostol Versus Misoprostol Only for Induction of Labor
Evaluation of safety \& efficacy of nitric oxide donors such as intravaginal isosorbide mononitrate in addition to misoprostol Versus misoprostol only for the whole process of induction of labor.
- Trial name
- NCT03523754
- Testing
- Isosorbide Mononitrate 40 MG to study group
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dina Yahia Mansour
Unfavorable Cervix for Induction of Labor
Induction of Labor in Patients With Unfavorable Cervical Conditions
Artificial ripening of the cervix and induction of labor remain as one of the therapeutic challenges in Obstetrics. The method widely used, the intravenous administration of Oxytocin, is associated with prolonged induction…
- Trial name
- NCT00604487
- Testing
- ARD (Atad Ripener Device), AID (Atad double balloon Instillation Device), folly catheter
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Obesity, Induction of Labor Affected Fetus / Newborn
Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term
Obesity increases the risk of pregnancy complications, including among others puerperal infections and cesarean delivery, and risk rises with increasing body mass index (BMI).
- Trial name
- APPOINT (NCT03801252)
- Testing
- Cefazolin, Azithromycin
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Obesity, Pregnancy
Randomized Controlled Trial: Induction of Labour of Obese Women With Dinoprostone or Single Balloon Catheter
The purpose of this study is to compare the efficacy of single balloon foley catheters to dinoprostone for the induction of labour of obese women.
- Conditions
- Obesity, Pregnancy, Labor, Induced
- Trial name
- NCT01962831
- Testing
- Dinoprostone, Single balloon foley catheter
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
Induction of Labor, Previous Cesarean Section
Labor Induction After Cesarean Section: Outcome, Hormonal Trends
Objectives- To compare changes in labour-associated maternal and fetal hormone levels during breast stimulation, balloon induction and spontaneous labour.
- Conditions
- Induction of Labor, Previous Cesarean Section, Hormonal Changes
- Trial name
- NCT04244747
- Testing
- induction of labor by breast stimulation, induction of labor by catheter balloon
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Cesarean Delivery
A RCT of Labor Induction at 39 Weeks in Low - Risk Women in China
The investigators are committed to identifying the optimal timing of delivery for low-risk pregnancies. While current guidelines typically recommend induction at 41 weeks, emerging evidence suggests that elective induction at 39…
- Trial name
- LIRIC (NCT07082530)
- Testing
- Labor Induction at 39 Weeks, Expectant management
- Where
- China
- Volunteers
- 1,074 people, healthy volunteers welcome
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Labor (Obstetrics)--Complications
Uterocervical Angle Versus Cervical Length as a Predictor of Labor Induction in Term Singleton Pregnancy
Induction of labor is frequently performed in all obstetric clinics. Failed IOL has been defined in many different ways.Bishop scoring, which is a traditional and subjective method, is more frequently evaluated with cervical…
- Trial name
- NCT06558500
- Testing
- Uterocervical angle
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Labor Induction
Dinoprostone Vaginal Insert Versus Double Balloon Catheter for Preinduction Cervical Ripening
Effıcacy of dinoprostone vaginal insert versus double- balloon catheter among women in the induction of labor
- Trial name
- NCT03016442
- Testing
- Cook Double Balloon Catheter, Dinoprostone
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Induction of Labor, Unfavorable Cervix
Cervical Ripening With the Double Balloon Device for 6 Hours Compared With 12 Hours
This study will evaluate the insertion of double balloon device (DBD) for cervical ripening for 12 h vs 6 hours.
- Trial name
- DoubleCRIB (NCT03045939)
- Testing
- cervical ripening device
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Termed Pregnancy With Indications for Labor Induction.
Oral Versus Vaginal Misoprostol for Induction of Labor
The purpose of this study is to compare the efficacy between a single dose of oral misoprostol 100 microgram and vaginal misoprostol 50 microgram for induction of labor.
- Trial name
- NCT00148473
- Testing
- Misoprostol
- Where
- Thailand
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Gestational Diabetes, Induction of Labor Affected Fetus / Newborn
The Best Timing of Delivery in Women With GDM Study
The investigatiors aimed to conduct a well-designed RCT to firstly focus on GDM women controlled with only diet and exercise, and provide an optimize process on their timing and mode of delivery
- Trial name
- NCT03928899
- Testing
- New procedure
- Where
- China
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Induction of Labor
Foley Labor Induction Trial at Term and in PROM
This study is considering current standard oxytocin dosing regimen in combination with Foley bulb for cervical ripening is associated with improved outcomes including greater percentage of women delivered within or less than 24…
- Trial name
- NCT02098421
- Testing
- Oxytocin
- Where
- 2 sites in United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Induction of Labor, Cesarean
A Prospective Comparative Study of Induction of Labor With a Cervical Ripening Double Balloon vs Foley Catheter
Hypothesis: The induction of labor in patients with unfavorable Bishop score is a challenging obstetrical process, and may be influenced or complicated by the cervical ripening method used.
- Conditions
- Induction of Labor, Cesarean, Endometritis
- Trial name
- NCT00501033
- Testing
- Mechanical induction of labor, Double Balloon, Foley Catheter
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Labor, Induction
Induction of Labor in Term Premature Rupture of Membranes: A Comparison Between Oxytocin and Dinoprostone Followed Six Hours Later by Oxytocin
Prelabor rupture of membranes (PROM) is most commonly defined as rupture of membranes before the onset of labor and occurs in 8% of term pregnancies.
- Conditions
- Labor, Induction, PROM (Pregnancy)
- Trial name
- NCT01099280
- Testing
- SYNPITAN FORT 5 IU, Propess,SYNPITAN FORT
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital