Clinical trials: Lactation Disorders
Maturation of the Healthy Infant Intestinal Microbiota, Microbial Colonization
Bern Birth Cohort / Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach
Background: Intestinal microbiota composition is fundamental to human health and undergoes critical changes within the first two years of life.
- Conditions
- Maturation of the Healthy Infant Intestinal Microbiota, Microbial Colonization, Nutrition Disorder, Infant, Milk Expression, Breast
- Trial name
- BeBiCo (NCT04447742)
- Where
- Switzerland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Childhood Obesity Prevention, Childhood Obesity
Postnatal Exercise to Activate Baby's Brown Fat
The purpose of this study is to learn how exercise and physical activity during pregnancy and after pregnancy may affect the composition of breastmilk.
- Conditions
- Childhood Obesity Prevention, Childhood Obesity, Physical Activity, Lactation
- Trial name
- PEABaBy (NCT07467694)
- Testing
- Active group
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Breastfeeding, Anxiety Disorders
The Effect of Breastfeeding Support Provided Via Video-conferencing
A randomized control trial was made to examine the effects of breastfeeding support given by the video-conferencing method in the early postpartum period on anxiety, breastfeeding self-efficiency, and newborn outcomes.
- Conditions
- Breastfeeding, Anxiety Disorders, Neonatal Outcomes
- Trial name
- NCT04929561
- Testing
- Video-conferencing group
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Obesity, Infant Obesity
Preventing Early Childhood Obesity, Part 2: Family Spirit Nurture, Prenatal - 18 Months
This study aims to assess the impact of a home-visiting program, called "Family Spirit Nurture" (FSN), on reducing early childhood obesity in American Indian (AI) children.
- Conditions
- Obesity, Infant Obesity, Mother-Child Relations, Dietary Habits
- Trial name
- NCT03334266
- Testing
- Family Spirit Nurture (FSN), Injury Prevention Education (IPE), Optimized Standard Care (OSC)
- Where
- 3 sites in United States
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Allergies, Obesity
Effects of the Mediterranean Diet During Pregnancy on the Onset of Allergies in the Offspring
Allergy prevalence is increasing steadily with some describing as the "epidemic of the twenty-first century". Maternal diet during pregnancy has been linked to offspring allergy risk, so it represents a potential target for…
- Conditions
- Allergies, Obesity, Gestational Complications, Gestational Weight Gain
- Trial name
- PREMEDI (NCT05119868)
- Testing
- Nutritional intervention based on Mediterranean Diet
- Where
- 2 sites in Italy
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Federico II University
Reduce the Risk of Obesity During Infancy, Reduce the Risk of Insulin Resistance
Minimizing the Risk for Obesity During Infancy by Extensive Advisory Service
0-hypothesis: advisory support does not 1. prolong the the breast-feeding period 2. minimize the risk of obesity and metabolic dysfunction in infants of obese mothers
- Trial name
- NCT01235663
- Testing
- advisory support
- Where
- Denmark
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Covid19, Breastfeeding
Gestational Immunity for Transfer
This is a study prospective cohort study at an urban academic centre, with two parts: 1. Health outcomes, and maternally transferred antibodies, in babies born to mothers who had antenatal COVID-19 and convalesced before…
- Conditions
- Covid19, Breastfeeding, Vaccine Exposure Via Breast Milk
- Trial name
- GIFT (NCT04802278)
- Testing
- COVID-19 vaccine
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Insufficient Lactation
Improving Lactation Success in Black Mothers of Critically Ill Infants
Racial disparities result in Black infants in the neonatal intensive care unit (NICU) receiving less breast milk (BM) than White and Hispanic infants.1 BM improves infant health yet mothers of critically ill infants produce…
- Trial name
- NCT05147987
- Testing
- Hands free wearable breast pump
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Florida
Smartphone Addiction, Breastfeeding
SMaRT Mom - Smartphone Management and Responsive Time for Breastfeeding Mothers
In the last decade, infants are born into a social environment in which the smartphone has become an essential part of our lives.
- Conditions
- Smartphone Addiction, Breastfeeding, Infant Behavior, Mother-Infant Interaction
- Trial name
- SMaRT (NCT06030830)
- Testing
- SMaRT Mom
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Obesity, Metabolic Syndrome
Milk Types and Fish Oil in 9- to 12-Month-Old Infants
The objective of this intervention study is to examine the effect of whole cow's milk versus infant formula as primary milk sources with or without supplements of n-3 LCPUFA for growth, nutritional status, development, risk…
- Conditions
- Obesity, Metabolic Syndrome, Growth, Blood Pressure
- Trial name
- NCT00379171
- Testing
- Cow's milk with fish oil, Cow's milk without fish oil, Formula with fish oil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Low Birthweight Infant, Preterm
Exploring Minor Proteins and Peptides in Human Milk: a Proteomic Analysis Across Lactation Stages
Human milk (HM) is the optimal food source for the nutrition, growth, and development of newborns. The protein fraction of HM plays a crucial role in the healthy development of infants.
- Conditions
- Low Birthweight Infant, Preterm, Very Low Birth Weight Preterms
- Trial name
- PROTEOM-MILK (NCT06787963)
- Where
- 2 sites in Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Hyperbilirubinemia, Jaundice
Improving Health Outcomes for New Mothers and Babies
Because adherence to postnatal care guidelines across the United States (U.S.) is poor, newborns and mothers often are placed at undue risk for adverse medical and social outcomes.
- Conditions
- Hyperbilirubinemia, Jaundice, Dehydration, Postpartum Depression
- Trial name
- NCT00360204
- Testing
- Home Nurse Visit
- Where
- 2 sites in United States
- Volunteers
- 1,154 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Child Malnutrition, Breastfeeding
Impact of Behavior Change Communications and Market-based Approach to Delivering Micronutrient Powders on Stunting, Infant Feeding Practices and Anemia in Bangladesh
This complex evaluation of a large-scale program uses a cluster-randomized design where 20 geographic clusters (subdistricts) were randomized to study two sets of interventions.
- Conditions
- Child Malnutrition, Breastfeeding, Complementary Feeding, Childhood Anemia
- Trial name
- NCT01678716
- Testing
- EHC + BCC, Micronutrient powders, Mass media
- Where
- Bangladesh
- Volunteers
- 8,800 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Birth, First, Birth Outcome, Adverse
Reducing Turkey High Cesarean Section Rates
Considering the increasing rates of cesarean delivery in Turkey, we aimed to research the impact of antenatal education on pregnancy, the childbirth process, the cesarean section rate, and the postpartum period through a…
- Conditions
- Birth, First, Birth Outcome, Adverse, Breast Feeding
- Trial name
- NCT07799545
- Testing
- Antenatal education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Infant Malnutrition, Pregnant Women
Peer Conselling Infant Feeding Education Program
Child undernutrition remains a highly prevalent condition in low and middle income countries and a major portion of the global burden of childhood malnutrition is found in South Asia with an estimated 74 million children living…
- Conditions
- Infant Malnutrition, Pregnant Women, Lactating Mother, Breastfeeding
- Trial name
- NCT01333995
- Testing
- Peer counseling on infant feeding
- Where
- Bangladesh
- Volunteers
- 2,050 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Vitamin B 12 Deficiency
The Impact of Vitamin B12 Deficiency on Infant Gut Microbiota
Vitamin B12 plays important roles in DNA synthesis and neurological functions. Vitamin B12 deficiency is one of the most common micronutrient deficiencies and it has become increasingly more frequent in infants.
- Trial name
- NCT03365583
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lactation, Other Disorders of Bone Density and Structure
Longitudinal Lactation Bone Density Study
Changes in maternal calcium metabolism are necessary during lactation to provide adequate calcium in breast milk for development of the newborn skeleton.
- Conditions
- Lactation, Other Disorders of Bone Density and Structure, Endocrine; Complications
- Trial name
- NCT01630629
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Malnutrition
Assessing Cost and Effectiveness of Training and Supervision of Front Line Workers on Early Breastfeeding Practices
The aim of this operational research is to compare the cost-effectiveness of two methods for capacity building of existing TBAs/CVs to improve rates of delayed cord clamping, early skin to skin contact and infant-led initiation…
- Trial name
- iycfch (NCT01407224)
- Testing
- Improve Early Breastfeeding
- Where
- Bangladesh
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Eminence
Vitamin A Deficiency, HIV
Single-dose Postpartum Vitamin A Supplementation of Mothers and Neonates
The ZVITAMBO PROJECT is testing whether giving mothers and infants a single large dose of vitamin A during the immediate post partum period will reduce: 1.
- Trial name
- ZVITAMBO (NCT00198718)
- Testing
- Vitamin A (retinyl palmitate)
- Volunteers
- 28,220 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Fathers, Premature Birth
Study on the Treatment of Children and Their Families in Services Related to Early Childhood
Breastfeeding is recommended for preterm infants. Development of breastfeeding is an important issue, requiring the involvement of medical and paramedical staff in neonatal units.
- Trial name
- PERAM-QUAL (NCT02201433)
- Where
- 2 sites in France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest