Clinical trials: Laparoscopy.
Inhalation Anesthesia, Dexmedetomidine
The Impact of a Single Dexmedetomidine Bolus on Intraoperative Sevoflurane Consumption (DEXHALE)
Sevoflurane is a volatile agent easy to control thanks to the Minimum Alveolar Concentration (MAC) allowing its titration for an optimal depth of anesthesia.
- Conditions
- Inhalation Anesthesia, Dexmedetomidine, Sevoflurane, Laparoscopy
- Trial name
- NCT05615194
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Perioperative Care, Fluid Therapy
Paired Comparison of SVV and PVI Accuracy
This study will compare two operating-room monitors-stroke volume variation (SVV, from the arterial line) and the Pleth Variability Index (PVI, from the pulse oximeter)-to see which one more accurately predicts whether giving a…
- Conditions
- Perioperative Care, Fluid Therapy, Monitoring, Physiologic, Hemodynamics
- Trial name
- NCT07260890
- Testing
- Stroke Volume Variation (SVV) monitoring, Pleth Variability Index (PVI) monitoring
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Laparoscopic Skills Acquisition, Surgical Education and Skill Acquisition
Effect of Mobile Video Games on Laparoscopic Simulation Skills in Medical Students
This study evaluated whether regular mobile video game play could improve laparoscopic simulation performance among medical students without prior surgical or simulation experience.
- Conditions
- Laparoscopic Skills Acquisition, Surgical Education and Skill Acquisition, Simulation Training, Laparoscopy, Medical Students
- Trial name
- NCT07744399
- Testing
- Mobile Phone Gaming
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Hysterectomy, Laparoscopy
Tolerance of the vNOTES Surgical Technique in Total Hysterectomy for Benign Lesion. Clinical Trial of Non-inferiority Compared to the Laparoscopic Technique.
During a first consultation with an indication of total hysterectomy for a benign lesion, we will study the patient's eligibility.
- Conditions
- Hysterectomy, Laparoscopy, vNOTES
- Trial name
- VLAP (NCT05031182)
- Testing
- Laparoscopy, vNOTES
- Where
- 2 sites in France
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Surgery, Laparoscopic
Low Versus Standard Pressure Pneumoperitoneum on Shoulder Tip Pain
This proposed study is a single-center, double blind, parallel group RCT comparing the use of low (10 mm Hg) versus standard pressure (15 mm Hg) pneumoperitoneum at the time of benign gynecologic laparoscopic surgery.
- Conditions
- Surgery, Laparoscopic, Laparoscopy, Penumoperitoneum
- Trial name
- NCT06504277
- Testing
- Low Pressure Penumoperitoneum, Standard Pressure Group (No intervention- active comparator)
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Gynecologic Surgical Procedures, Gastric Injury
Surgeon Perception of Gastric Decompression at Time of Gynecologic Laparoscopy
The goal of this clinical trial is to test whether it is necessary to decompress the stomach during gynecologic laparoscopy. The main questions it aims to answer are: Is there appropriate visualization during surgery without…
- Conditions
- Gynecologic Surgical Procedures, Gastric Injury, Aspiration, Nausea, Postoperative
- Trial name
- NCT06137976
- Testing
- Gastric decompression (oropharyngeal or nasopharyngeal gastric tube)
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Sterilization Tubal, Salpingectomy
SALpingectomy for STERilization (SALSTER)
The SALSTER study is a register-based randomized clinical trial (R-RCT) that examines if laparoscopic salpingectomy instead of tubal ligation, as a contraceptive method, has no increased risk for complications and has no negative…
- Conditions
- Sterilization Tubal, Salpingectomy, Laparoscopy, Ovarian Reserve
- Trial name
- SALSTER (NCT03860805)
- Testing
- Laparoscopic tubal ligation, Laparoscopic bilateral salpingectomy
- Where
- Sweden
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Simulation Training, Laparoscopy
Comparing Skills Acquisition on Different Laparoscopy Software
Simulation based training is a standard part of surgical training. Over the years virtual reality simulator have been more and more integrated into the surgical curriculum for surgical novices.
- Trial name
- NCT06255080
- Testing
- Training intervention
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Leiomyoma, Laparoscopy
Combined Vaginal Misoprostol and Perivascular Vasopressin
Injection of Vasopressin into the uterine tissue surrounding fibroids constricts blood vessels, and has been found to be beneficial by decreasing blood flow to fibroids, and thereby resulting in less bleeding with removal.
- Conditions
- Leiomyoma, Laparoscopy, Uterine Myomectomy
- Trial name
- NCT03815344
- Testing
- Standard, Standard-vaginal misoprostol
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Antonios Likourezos
Hysterectomy, Laparoscopy
Optimization of Pre-operative Oral Analgesics in Patients Undergoing Ambulatory Minimally Invasive Hysterectomy
This is a randomized controlled trial comparing pre-admission administration of routine oral preoperative non-narcotic analgesics with the administration of these medications in the pre-anesthesia care unit per our standard…
- Conditions
- Hysterectomy, Laparoscopy, Analgesia
- Trial name
- NCT03420794
- Testing
- Timing of pre-operative oral non-narcotic analgesics in relation to minimally invasive hysterectomy
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Functional Recovery, Laparoscopy
Comparison of Functional Recovery Between Laparoscopic and Open Pancreaticoduodenectomy
Laparoscopic surgery has not changed much in safety compared with open surgery through many existing studies, and has become a procedure to help patients' recovery.
- Conditions
- Functional Recovery, Laparoscopy, Periampullary Cancer
- Trial name
- NCT03870698
- Testing
- Laparoscopic group
- Where
- South Korea
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Autonomic Nervous System, Nerve Block
Heart Rate Variability and Electroencephalography Analysis in Laparoscopic Surgery With or Without Transversus Abdominis Plane Block
Heart rate variability(HRV) and electroencephalography(EEG) has been used widely in anesthetic practice nowadays. One of the most dominant applications is the nociception-analgesia balance.
- Conditions
- Autonomic Nervous System, Nerve Block, Laparoscopy, Anesthesia and Analgesia
- Trial name
- NCT04539080
- Testing
- transversus abdominis plane block
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Prolapse Uterovaginal, Prolapse Bladder
Laparoscopic Central and Anterior Compartment Prolapse Surgery: A Meshless Sacrocolpopexy Technique
Mesh is widely applied in the abdominal approach to pelvic organ prolapse surgery, and sacrocolpopexy-sacrohysteropexy is the gold standard application, particularly for central compartment abnormalities.
- Conditions
- Prolapse Uterovaginal, Prolapse Bladder, Laparoscopy
- Trial name
- NCT05558852
- Testing
- Laparoscopic Meshless Sacrocolpopexy Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Laparoscopy, Augmented Reality
Laparoscopic Augmented Reality for Identification of Liver Lesions - a Pre-clinical Randomized Cross-over Trial
Procedure preparation and accurate knowledge of the specific anatomy is an integral part of performing minimally invasive procedures.
- Conditions
- Laparoscopy, Augmented Reality, Orientation, Spatial, Liver
- Trial name
- LARA (NCT05389241)
- Testing
- Method A, Method B
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Köln
Morbid Obesity, Hernia
Minimally Invasive Surgery (MIS) Database for the Purpose of Research
The Minimally Invasive Surgery Team (MIST) are establishing a separate research database to find out more about patient's undergoing minimally invasive surgery (laparoscopic , open and robot assisted) procedures at UCSD.
- Conditions
- Morbid Obesity, Hernia, Colorectal Cancer, Laparoscopy
- Trial name
- NCT00535990
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Laparoscopy
Effect of Abdominal Binder After Laparoscopic Cholecystectomy on Enhanced Recovery
There have been reports that abdominal binder use after laparoscopic or open surgery affects postoperative respiratory function, walking performance, and pain but no study has evaluated binder use solely for laparoscopic…
- Trial name
- NCT04787458
- Testing
- abdomen binder (Sejung Korea, Seoul, Republic of Korea)
- Where
- South Korea
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Kangbuk Samsung Hospital
Laparoscopy
Effect of Video-based Guided Self-reflection on Intraoperative Skills
While video-assisted structured feedback by expert surgeons significantly improves laparoscopic skill acquisition in surgical trainees, this method is resource intensive and may have limited feasibility outside of research…
- Trial name
- NCT04643314
- Testing
- Guided video-based self-evaluation
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Benign Neoplasm of Cervix Uteri, Gynecological Laparoscopy
The Effects of CO2 Pneumoperitoneum at Different Temperature in Laparoscopic Surgery
Objective: It is recommended to heat and humidify CO2 in laparoscopic surgery to prevent postoperative pain and hypothermia but information about its effects on hemodynamic and respiratory parameters is limited.
- Trial name
- NCT04508387
- Testing
- Group HH (heated-humidified)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Laparoscopy
Comparison of the Effectiveness of 2D Versus 3D Basic Laparoscopic Skills Training
The aim of this study is to find out whether basic laparoscopic skills training (FLS tasks) on a standard pelvic trainer using conventional 2D visualization is at least equally effective in terms of skills improvement compared to…
- Trial name
- NCT03763903
- Testing
- 3D training, 2D training
- Where
- Austria
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Increase in Intra-abdominal Pressure, Increase in Intracranial Pressure (ICP)
Changes in Cerebral Oxygenation Studies During Laparoscopy Procedure
The motivation results from the fact, that an intra-abdominal pressure is correlated with cerebral perfusion, in a mechanism of reducing venous outflow.
- Conditions
- Increase in Intra-abdominal Pressure, Increase in Intracranial Pressure (ICP), Laparoscopy, Cerebral Perfusion and Oxygenation
- Trial name
- NCT03640741
- Testing
- Laparoscopy
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences