Clinical trials: Laparotomy Closure After Abdominal Surgery
Incisional Hernia After Midline Laparotomy, Quality of Life (QOL)
NoPro - Norwegian Hernia Prophylaxis Study
A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh.
- Conditions
- Incisional Hernia After Midline Laparotomy, Quality of Life (QOL), Burst Abdomen, Surgical Site Infections
- Trial name
- NoPro (NCT06858020)
- Testing
- Prophylactic polypropylene onlay mesh
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Sykehuset Innlandet HF
Surgical Site Infection
Comparison Of Outcome Of Antibiotic Coated Vicryl Vs Non-Coated Vicryl In Abdominal Fascial Closure After Laparotomy In Children
We are investigating outcome of antibiotic coated vicryl versus non coated vicryl in terms of rate of surgical site infection and lebgth of hospital stay in children after lalaprotomy for perforated viscera.
- Trial name
- NCT06129773
- Testing
- antibiotic coated vicryl used for fascial closure
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Muhammad Adeel Ashiq
Laparotomy Closure After Abdominal Surgery
Comparing Delayed vs Primary Wound Closure After Emergency Laparotomy: Impact on Infection, Healing, and Hospital Stay
The purpose of this study is to find out which type of wound closure after emergency abdominal surgery leads to fewer wound infections and better recovery: closing the wound immediately after surgery (called primary closure) or…
- Trial name
- NCT07142395
- Testing
- Immediate skin closure, Delayed primary closure
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Bkahtawar Amin Medical and Dental College Multan
Wound Infection, Incisional Hernia
PDS*Plus and Wound Infections After Laparotomy
The aim of this study is to ascertain if the use of PDS plus® reduces the number of wound infections and incisional hernia after midline and transverse laparotomy comparing to polyglactin suture.
- Trial name
- PDS*plus (NCT00998907)
- Testing
- PDS plus, PDS II
- Where
- Germany
- Volunteers
- 1,042 people
- Sponsor
- University Hospital, Saarland
Surgical Wound Dehiscence
Abdominal Wall Dehiscence After Laparotomy Closure in Abdominal Surgery: a Retrospective Observational Study on the Influence of the Suture Used
In this retrospective longitudinal observational study we compare the incidence of fascial dehiscence and incisional hernia in patients operated via abdominal wall incision, comparing the barbed suture Stratafix Symmetric to…
- Trial name
- SUTURA (NCT06501508)
- Testing
- Stratafix Symmetric
- Where
- 4 sites in Spain
- Volunteers
- 1,900 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Laparotomy Closure After Abdominal Surgery, Suture Materials
Comparison of Vicryl Versus Prolene for Midline Rectus Sheath Closure After Elective Laparotomy
This randomized controlled trial compared two commonly used suture materials, Prolene and Vicryl, for closing the midline rectus sheath after elective laparotomy.
- Conditions
- Laparotomy Closure After Abdominal Surgery, Suture Materials, Complications Wounds
- Trial name
- NCT07451990
- Testing
- Vicryl (Polyglactin 910) Suture, Prolene (Polypropylene) Suture
- Where
- Pakistan
- Volunteers
- 152 people
- Sponsor
- Hayatabad Medical Complex
Dehiscence of Laparotomy Wound, Surgical Wound Infection
Short Stitch Monomax®
A number of studies identifies abdominal hernia as the most frequent postoperative complication following laparotomy with percentages of 9-20% - depending on duration of follow-up.
- Trial name
- Short-Stitch (NCT01938222)
- Testing
- Short Stitch
- Where
- Germany
- Volunteers
- 351 people
- Sponsor
- Diakonie-Klinikum Schwäbisch Hall gGmbH
Laparotomy, Dehiscence Wound
Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT
This randomized control trial aims to compare the efficacy of triclosan-coated barbed suture (TCB) versus conventional non-barbed polydioxanone (PDS) suture in the closure of the abdominal fascia after emergency exploratory…
- Conditions
- Laparotomy, Dehiscence Wound, Surgical Site Infections, Trauma Abdomen
- Trial name
- NCT06043414
- Testing
- triclosan-coated barbed suture, triclosan-coated non-barbed suture, Non-coated non-barbed suture
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Southern California
Laparotomy Closure After Abdominal Surgery, Wound Infection, Surgical
Effect of Continuous Versus Interrupted Suturing on Wound Dehiscence and Infection After Abdominal Surgery
The goal of this clinical trial is to learn whether the type of suturing technique used to close the abdomen after exploratory laparotomy affects the rate of wound complications.
- Conditions
- Laparotomy Closure After Abdominal Surgery, Wound Infection, Surgical, Dehiscence of Laparotomy Wound, Suture, Interrupted
- Trial name
- NCT07241507
- Testing
- Continuous suturing, Interrupted suturing
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Allama Iqbal Teaching Hospital
Wound Complication
Comparing Wound Complications After Elective Abdominal Surgery Using Two Closure Techniques
Wound complications, increased hospital stays and post-operative morbidity are all common following abdominal surgery. Abdominal closure complications are strongly associated with the closure technique and material used.
- Trial name
- COFACTOR (NCT03527433)
- Testing
- New closure technique
- Where
- Lebanon
- Volunteers
- 274 people
- Sponsor
- American University of Beirut Medical Center
Hernia Incisional, Suture, Complication
DuraMesh Laparotomy Closure Following Trauma and Emergency Surgery
The proposed project aims to evaluate the safety of DuraMesh™ suture for laparotomy closure in an emergent setting, while also providing preliminary efficacy data with regard to incisional hernia prevention.
- Trial name
- NCT04312165
- Testing
- Duramesh Laparotomy Closure, Conventional suture closure
- Where
- 2 sites in United States
- Sponsor
- Uniformed Services University of the Health Sciences
Laparotomy Closure After Abdominal Surgery
Duramesh™ vs Polydioxanone Suture for Laparotomy Closure
This study is intended to demonstrate the non-inferiority of a Duramesh closure as compared to a polydioxanone closure for early surgical site events (SSE) (< 1 month), and Duramesh superiority to polydioxanone for the…
- Trial name
- MOMENTUM RCT (NCT05804136)
- Testing
- Duramesh, Polydioxanone suture
- Where
- Belgium
- Volunteers
- 230 people
- Sponsor
- University Hospital, Ghent
Laparotomy
Abdominal Wall Closure After Laparotomy in Oncologic Surgery
The REBUILD Study is a first-in-human evaluation of the safety and performance of REBUILD Bioabsorbable.
- Trial name
- REBUILD (NCT05041530)
- Testing
- REBUILD Bioabsorbable
- Where
- 2 sites in Colombia
- Volunteers
- 30 people
- Sponsor
- AbSolutions Med Inc.
Incisional Hernia After Midline Laparotomy, Emergency Abdominal Surgery
Prophylactic Mesh Reinforcement Versus Primary Closure After Emergency Midline Laparotomy (PREEMPT)
The PREEMPT trial is a multicenter randomized controlled trial comparing prophylactic onlay biosynthetic mesh reinforcement with primary suture closure in adult patients undergoing emergency midline laparotomy.
- Trial name
- PREEMPT (NCT07753551)
- Testing
- Prophylactic Biosynthetic Mesh Placement, Direct suture
- Where
- Italy
- Volunteers
- 189 people
- Sponsor
- University of Rome Tor Vergata
Abdominal Wall Wound
MonoMax for Abdominal Wall Closure
A great number of different suture techniques and suture materials are in use in order to reconstitute the abdominal wall integrity, but there is no surgical gold standard for abdominal wall closure until today.
- Trial name
- MULTIMAC (NCT01901068)
- Testing
- MonoMax
- Where
- 3 sites in Czechia, Romania
- Volunteers
- 200 people
- Sponsor
- Aesculap AG