Clinical trials: Laparotomy Patients
Female Reproductive Cancer
Feeding Schedules After Surgery in Patients With Gynecologic Cancer
RATIONALE: Abdominal pain and nausea and vomiting may be lessened by waiting after surgery before eating foods by mouth. It is not yet known which feeding schedule is more effective in patients undergoing surgery.
- Trial name
- NCT00742677
- Testing
- nutritional support
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- European Institute of Oncology
Hernia Incisional
The Mesh-RTL Project, for Prevention of Incisional Hernia
Introduction: By definition, the laparotomy is a surgical incision into the abdomen cavity performed to examine the abdominal and retroperitoneal organs.
- Trial name
- RTL (NCT04134455)
- Testing
- Mesh reinforcement, RTL reinforcement
- Where
- Mexico
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Gynecologic Neoplasms, Abdominal Neoplasms
Augmented Pulse Pressure Variation to Predict Fluid Responsiveness in Open Laparotomy
Pulse pressure variation (PPV) is a well-known and widely used dynamic preload indicator based on heart-lung interaction to predict fluid responsiveness.
- Trial name
- NCT02653469
- Testing
- Augmented ventilation, Fluid loading
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Samsung Medical Center
Geriatric Presentation of Urinary Tract Infection, Acute Kidney Injury
Intraoperative NGAL Level in Geriatric Patients Undergoing Laparotomy
The aim of this study is to detect early renal dysfunction that may occur during the surgical procedure in geriatric patients who will undergo laparotomy surgery.
- Trial name
- NCT05030727
- Testing
- record of pNGAL
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Colorectal Cancer, Metastatic Cancer
SCH 66336 Before Surgery in Treating Patients With Colorectal Cancer That Has Metastasized to the Liver
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Randomized phase I trial to compare the effectiveness of different doses of SCH 66336 before surgery…
- Trial name
- NCT00005030
- Testing
- SCH 66336, conventional surgery
- Sponsor
- M.D. Anderson Cancer Center
Abdomen, Acute, Surgery--Complications
Survival After Emergency Laparotomy in Octogenarians
In this single-center retrospective study we wanted to investigate mortality and postoperative complications after emergency laparotomy performed in patients aged 80 years or above.
- Conditions
- Abdomen, Acute, Surgery--Complications, Postoperative Complications, Frailty
- Trial name
- NCT04176432
- Testing
- No intervention
- Volunteers
- 106 people
- Sponsor
- Haukeland University Hospital
Pain Monitor During Anesthesia
Observational Evaluation of the Last Version of the PMD200TM
Title: Evaluation of the last version of the PMD200TM and its NoL index in patients undergoing laparotomies with intraoperative epidural analgesia Objectives: Measure NoL Index changes after a standardized nociceptive electrical…
- Trial name
- NCT02884778
- Testing
- Detection of pain after nociceptive stimulus
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Deep Venous Thromboses, Laparotomy Patients
Comparative Efficacy of Rivaroxaban and Enoxaparin in Post-Laparotomy DVT Prevention
The goal of this clinical trial is to learn if rivaroxaban works better than enoxaparin to prevent deep vein thrombosis (DVT) after emergency exploratory laparotomy in adults.
- Trial name
- NCT07243080
- Testing
- rivaroxaban (10mg), Enoxaparin 40 mg SC
- Where
- Pakistan
- Volunteers
- 212 people
- Sponsor
- Mayo Hospital Lahore
Laparotomy Closure After Abdominal Surgery
Comparing Delayed vs Primary Wound Closure After Emergency Laparotomy: Impact on Infection, Healing, and Hospital Stay
The purpose of this study is to find out which type of wound closure after emergency abdominal surgery leads to fewer wound infections and better recovery: closing the wound immediately after surgery (called primary closure) or…
- Trial name
- NCT07142395
- Testing
- Immediate skin closure, Delayed primary closure
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Bkahtawar Amin Medical and Dental College Multan
Incisional Hernia, Emergency Midline Laparotomy
The Time-Dependent Development of Incisional Hernias in Emergency Laparotomy Incisions of High-Risk Patients
The aim of this study is to describe the development of symptomatic and asymptomatic incisional hernias after emergency midline laparotomy over time in high-risk patients evaluated by consecutive MRI-scans.
- Trial name
- MAGELA (NCT05528692)
- Testing
- Magnetic resonance imaging (MRI)
- Where
- Denmark
- Sponsor
- Herlev Hospital
Emergencies, Frail Older Adult
Emergency Laparotomy and Frailty Study
Patients aged over 65 comprise more than half the emergency general surgical workload, however, available risk-prediction tools for such patients are extrapolated from younger cohorts.
- Conditions
- Emergencies, Frail Older Adult, Laparotomy
- Trial name
- ELF (NCT02952430)
- Testing
- Emergency laparotomy
- Volunteers
- 500 people
- Sponsor
- North Western Research Collaborative
Rectal Cancer
Rectal Surgery Evaluation Trial (RESET)
Total mesorectal excision (TME) is the standard of care for rectal cancer, which can be combined with low anterior resection (LAR) in patients with mid-to-low rectal cancer.
- Trial name
- RESET (NCT03574493)
- Testing
- TME with LAR
- Where
- France
- Volunteers
- 1,098 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Midline Laparotomy
COMPARISON OF MEAN DURATION OF POST OPERATIVE ANALGESIA FOLLOWING ADDITION OF DEXMEDETOMIDINE TO ROPIVACAINE VERSUS PLAIN ROPIVACAINE ON ULTRASOUND GUIDED RECTUS SHEATH BLOCK
To compare the mean duration of postoperative analgesia following addition of dexmedetomidine to ropivacaine versus plain ropivacaine in ultrasound guided rectus sheath block in patients undergoing midline laparotomies
- Trial name
- NCT07254130
- Testing
- Rectus Sheath Block
- Where
- Pakistan
- Volunteers
- 209 people
- Sponsor
- Quaid-e-Azam Medical College
Pain, Postoperative, Opioid Use
"Dexa vs Dexmedetomidine With Bupivacaine in TAP Block for Laparotomy Analgesia
Transversus abdominis plane block is a regional anesthetic technique which blocks the abdominal neural afferents by introducing local anesthetic into the neuro-fascial plane between the internal oblique and the transversus…
- Conditions
- Pain, Postoperative, Opioid Use, Laparotomy
- Trial name
- NCT07590752
- Testing
- Bupivacaine Hcl 0.25% Inj_#1, Bupivacaine Hcl 0.25% Inj_#2
- Where
- Pakistan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Emergency Abdominal Surgery
Physiotherapy After Emergency Laparotomy in the Elderly
Emergency laparotomy is associated with high postoperative morbidity and mortality. This risk is particularly high among elderly patients, who often present with reduced physiological reserve, frailty, and multimorbidity.
- Trial name
- NCT07504185
- Testing
- Experimental (Structured postoperative physiotherapy), Standard postoperative care
- Where
- Cyprus
- Volunteers
- 250 people
- Sponsor
- University of Cyprus
Fascial Closure
Optimal Method of Fascial Closure in High Risk Patients Undergoing Laparotomy
The primary objective of this study is to identify the optimal method of fascial closure of a laparotomy incision in high risk patients for intra-abdominal complications.
- Trial name
- NCT02145052
- Testing
- Continuous suture, Interrupted suture
- Where
- United States
- Volunteers
- 388 people
- Sponsor
- Massachusetts General Hospital
Neurogenic Bladder Disorder, Bladder Dysfunction
Urinary Artificial Sphincter in Children
Retrospective monocentric study of the outcomes of patients with neurogenic bladder who had a urinary artificial sphincter before the age of 18 years old.
- Conditions
- Neurogenic Bladder Disorder, Bladder Dysfunction, Spina Bifida, Urinary Incontinence Due to Urethral Sphincter Incompetence
- Trial name
- SUAPED (NCT06734429)
- Testing
- Urinary Artificial Sphincter
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Clermont-Ferrand
Incisional Hernia, Abdominal Aortic Aneurysm
Aneurysma Hernia Study - Incidence of Incisional Hernias After Abdominal Aortic Aneurysm Repair
Principles= Prevention of incision hernias by primary closure of mid line laparotomies with the best-evidenced suture techniques.
- Trial name
- АНЕУРИЗМА (NCT02012270)
- Testing
- PRINCIPLES technique, Conventional group
- Where
- 2 sites in Poland, Serbia
- Volunteers
- 240 people
- Sponsor
- Igor Koncar
Laparotomy, Gynecologic Diseases
Enhanced Recovery After Surgery: A RCT of Perioperative Management of Gynecologic Patients
This is a single-blinded randomized control trial comparing the current perioperative care of the investigators gynecologic oncology patients with a standardized perioperative "enhanced recovery" pathway.
- Trial name
- NCT02357251
- Testing
- Enhanced recovery protocol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Case Comprehensive Cancer Center
Effects of Coffee Ingestion on Recovery of Bowel Function
>The Purpose of This Study Was to Determine Whether Consuming a 100-mL Cup of Coffee is Effective in Preventing or Reducing Postoperative Ileus After Laparotomy of Benign Gynecological Patients
Comparison of the effectiveness coffee (with or without caffeine) ingestion and water for reducing the duration of Postoperative ileus after Laparotomy of Benign Gynecological Patients
- Trial name
- NCT03660267
- Testing
- caffeine coffee, decaffiene coffee, still water
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand