Clinical trials: Laser
Cataract, Healthy
Dynamic Light Scattering Device (DLS) Study of Age-Related Changes in the Lens and Cataracts
This study will use a newly developed instrument called dynamic light scattering device (DLS) to examine age-related changes in the human lens and to study the causes and development of cataracts.
- Trial name
- NCT00007215
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Oral Health
Quaternary Ammonium Methacryloxy Silicate-containing Acrylic Resin
One of the major challenges in orthodontic treatment is long-term stability. Because removable retainers are worn for at least one year, bacteria and fungi may accumulate on the retainers in the form of multi-species plaque…
- Trial name
- NCT02525458
- Testing
- QAMS-containing PMMA, QAMS-free PMMA
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Frank Tay, BDSc (Hons), PhD
Tattoo Removal
Pilot Study of Multi-wavelength Laser for Tattoo Removal
To evaluate the safety and efficacy of an investigational version of the Cutera enLighten laser that offers muliple wavelengths for tattoo removal.
- Trial name
- NCT03290547
- Testing
- Cutera enLighten laser
- Where
- 2 sites in United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Crowding of Anterior Maxillary Teeth
Clear Aligner Treatment With and Without Low Level Laser Therapy for Upper Incisor Crowding
The goal of this clinical trial is to assess the effect of Low Level Laser Therapy (LLLT) on Upper Incisor Crowding using Clear Aligner Treatment (CAT).
- Trial name
- NCT06493721
- Testing
- Clear Aligner Treatment, Low level laser
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Facial Swelling, Pain
Effects of Low-level Laser Therapy After Surgical Removal of Impacted Lower Third Molar
Goal: The aim of this study was to evaluate the effects of low-level laser (LLL) after surgical removal of impacted lower third molars (ILTM).
- Conditions
- Facial Swelling, Pain, Trismus
- Trial name
- NCT04280809
- Testing
- GaAlAs laser
- Where
- Vietnam
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Androgenetic Alopecia
Treatment of Androgenetic Alopecia in Males and Females
The purpose of this study is to evaluate the efficacy of Low Level Laser and Light Therapy system configured in a novel product called the TopHat 655 system, for promoting hair growth in males and females diagnosed with…
- Trial name
- LLLT (NCT01437163)
- Testing
- TopHat 655 rejuvenation system, Laser and/or Light Hair Rejuvenation System
- Where
- 4 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Apira Science, Inc.
Anisometropia
Ten-year Follow-up of Laser in Situ Keratomileusis in Patients 8 to 15 Years Old
The purpose of this study is to determine the safety, efficacy, predictability, and stability of laser in situ keratomileusis (LASIK) to correct high anisometropia in patients 8 to 15 years old in whom conventional treatments…
- Trial name
- NCT00800774
- Testing
- LASIK
- Where
- Brazil
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Instituto de Olhos de Goiania
Pulpotomy
Evaluation of Low Level Laser Therapy in Primary Tooth Pulpotomy Treatment
In our study, it was aimed to compare the long-term effectiveness of diode laser and low level laser therapy and primary tooth amputation treatments using calcium hydroxide (LLLT+CH) in primary second molars with deep dentinal…
- Trial name
- NCT05680285
- Testing
- diode lazer, low level diode laser
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Uşak University
Periodontitis
Diode Laser and SRP in Chronic Periodontitis
The purpose of this study is to compare the efficacy of photoablative and photodynamic diode laser in adjunct to scaling-root planing (PAPD+SRP) and SRP alone for the treatment of periodontitis.
- Trial name
- PAPD (NCT02407379)
- Testing
- PAPD+SRP
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Odontostomatologic Laser Therapy Center, Florence, Italy
Cornea, Refractive Surgery
Evaluation of the Effect of Myopic Femtosecond Laser Assisted-LASIK on Anterior Chamber Flare Values and Corneal Endothelial Cells: A Prospective Before-and-After Study
This study aimed to investigate whether femtosecond laser-assisted LASIK (FS-LASIK) surgery causes inflammation in the anterior chamber and to analyze its effect on endothelial cells.
- Conditions
- Cornea, Refractive Surgery, Anterior Chamber Inflammation
- Trial name
- NCT04899258
- Testing
- Femtosecond laser assisted LASIK
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Skin Aging, Transepidermal Water Loss
Microneedle Versus Fractional CO₂ Laser for Skin Aging Treatment With Stem Cell Secretome in Indonesian Adult Women
Evidences regarding the effectiveness of adipose-derived mesenchymal stem cells (ADMSCs) secretome to alleviate skin aging have been extensively available, yet no studies hitherto directly investigated the best administration…
- Trial name
- NCT05508191
- Testing
- Fractional CO₂ Laser, Microneedle
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shannaz Nadia Yusharyahya
Dental Caries
Er:YAG Laser for Dental Cavity Preparation
The goal of this clinical trial is to compare Er:YAG laser cavity preparation with conventional rotary instruments in adults who have permanent premolars planned for extraction as part of orthodontic treatment.
- Trial name
- NCT07831720
- Testing
- Er:YAG Laser, Conventional Rotary Cavity Preparation
- Where
- Vietnam
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ho Chi Minh City Odonto-Stomatology Hospital
Physiology of Microvascular Skin
Microvascular Function Assessment in Healthy Subjects
Current stimulation induces microvascular dilation in human skin. The investigators aimed to study (1) whether the current vasodilation is amplified after two segmental current stimulation as compared to one stimulation; (2)…
- Trial name
- MICROTEC (NCT01572961)
- Testing
- acetylsalicilic acids (Aspirin)
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Laser Burn, Gingival Disease
Comparison of Sample Biopsy Using Scalpel or Er:YAG Laser
For certain changes in the oral mucosa a histopathological examination of the affected tissue is indicated to confirm the diagnosis. The gold standard is the biopsy by scalpel.
- Conditions
- Laser Burn, Gingival Disease, Biopsy Wound
- Trial name
- NCT03638973
- Testing
- Biopsy
- Where
- Switzerland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Overweight and Obesity, Weight Loss
Low-level Laser and Lifestyle Modifications
The purpose of this research study is to evaluate the effectiveness of Low Level Laser Therapy in combination with Lifestyle Modifications in helping people reduce the extra weight and size in the central body region
- Trial name
- LLLT (NCT05083442)
- Testing
- Low Level Laser Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Irritable Bowel Syndrome
ConfocAl endomicroSCopy bAsed Diet Trial in IBS
After a thorough baseline evaluation, IBS patients will be exposed to nutrients while undergoing confocal laser endomicroscopy (CLE).
- Trial name
- CASCADE (NCT05097872)
- Testing
- Diet
- Where
- Belgium
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Diabetic Nephropathies
Effect of High-intensity Laser Exercise Versus Moderate-intensity Aerobic Exercise on Diabetic Polyneuropathy Patients
Diabetic poly neuropathy (DPN) is a length-dependent, symmetrical sensorimotor poly neuropathy and is among the most prevalent and challenging consequences of diabetes4.
- Trial name
- NCT06884462
- Testing
- High-intensity laser (HIL), moderate-intensity aerobic exercise
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Deraya University
Striae; Albicantes
Stretch Marks on Abdomen
The primary objective of this study is to determine the effect of Stratacel® wound dressing on cosmetic outcomes following 1064/532nm picosecond laser (Picoway®, Syneron Candela Corp, Wayland, MA, USA) treatment of abdominal…
- Trial name
- NCT03750422
- Testing
- Picoway, Stratacel, Aquasonic
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Chronic Shoulder Pain
The Effect of High-intensity Laser Therapy in Patients With Chronic Shoulder Pain
The aim of this study was to investigate the effects of biostimulating, analgesic and noninvasive high intensity laser therapy on pain, functionality and quality of life in patients with chronic shoulder pain.
- Trial name
- NCT05062941
- Testing
- Conventional physiotherapy, High-intensity laser therapy (HILT)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Marmara University
Chronic Heart Failure, Coronary Disease
Role of Endothelial Function, Muscular Fitness and Metabolism in Functional Activity in Patients With Chronic Heart Failure (CHF)
Shortness of breath, fatigue, and exercise intolerance are clinical symptoms of chronic heart failure (CHF). Recent studies suggested that peripheral impairment was the major cause of clinical symptoms, and mechanism may be…
- Conditions
- Chronic Heart Failure, Coronary Disease, Dilated Cardiomyopathy
- Trial name
- NCT01139086
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
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