Clinical trials: Lasers
Nausea, Vomiting
Placebo in Acupuncture
Placebo control in acupuncture research is challenging and difficult. The primary objective of the study is to explore a study design comparing stimulation by real acupuncture needle, sham acupuncture needle and laser.
- Trial name
- NCT01054495
- Testing
- Acupuncture, Laser acupuncture
- Where
- 2 sites in Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Research Centre of Complementary and Alternative Medicine, Norway
Recurrent Head and Neck Squamous Cell Carcinoma
A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in First-line Treatment of Locoregional Recurrent Squamous Cell Carcinoma of the Head and Neck With No Distant Metastases
The goal of this clinical trial is to learn if ASP-1929 photoimmunotherapy (PIT) in combination with pembrolizumab works to treat recurrent squamous cell cancer of the head and neck (HNSCC) with no distant metastases.
- Trial name
- ECLIPSE (NCT06699212)
- Testing
- ASP-1929 Photoimmunotherapy, Pembrolizumab, Carboplatin
- Where
- 22 sites in United States, Japan and 1 more
- Volunteers
- 412 people
- Sponsor
- Rakuten Medical, Inc.
Diabetic Retinopathy, Diabetes Complications
Study Evaluating Efficacy and Safety of PF-04523655 Versus Laser in Subjects With Diabetic Macular Edema
To evaluate the effectiveness of study drug in improving visual acuity compared to laser treatment in the patients with diabetic macular edema
- Trial name
- DEGAS (NCT00701181)
- Testing
- Laser Treatment, PF-04523655 high, PF-04523655 middle
- Where
- 53 sites in United States, Denmark and 6 more
- Volunteers
- 184 people
- Sponsor
- Quark Pharmaceuticals
Carpal Tunnel Syndrome (CTS)
Comparison of Rest Splints vs High-Intensity Laser Therapy in Carpal Tunnel Syndrome
The aim of this study is to compare the effectiveness of rest splints and high-intensity laser therapy(HILT) added to physical therapy programs for patients with carpal tunnel syndrome in terms of pain, function, nerve conduction…
- Trial name
- NCT07294157
- Testing
- Rest splint group, high-intensity laser therapy (HILT)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Afyonkarahisar Health Sciences University
Restenosis
Study to Evaluate the Safety and Performance of Spectranetics Laser w/Adjunct PTA and Gore Viabahn Endoprosthesis for Treatment of SFA Instent Restenosis
A Multicenter study to evaluation the safety and performance of Spectranetics Laser with Adjunct PTA and Gore Viabahn Endoprosthesis for the Treatment of SFA Instent Restenosis
- Trial name
- SALVAGE (NCT00712257)
- Testing
- Spectranetics Laser with adjunct PTA and Gore VIABAHN Endoprosthesis with Heparin Bioactive Surface
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- VIVA Physicians
Post Laser Vision Correction Pain and Discomfort
Laser Vision Correction Use of an Eye Shield for Maintaining Vision and Mitigating Pain
The purpose of this research is to determine if an investigational thin shield can effectively reduce discomfort following Laser Vision Correction.
- Trial name
- NCT01675375
- Testing
- Eye Shield
- Where
- 5 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- FORSIGHT Vision3
Benign Prostatic Hyperplasia (BPH)
Phase 4 Study of Greenlight XPS Laser Versus BiVAP Saline Vaporization of the Prostate in Men With Symptomatic Benign Prostatic Hyperplasia
This is a Phase 4, prospective, open-label, randomized study of Greenlight XPS Laser versus BiVAP Saline Vaporization of the prostate in men with symptomatic Benign Prostatic Hyperplasia (BPH).
- Trial name
- NCT01500057
- Testing
- Greenlight XPS Laser, BiVAP Saline Vaporization of the prostate
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Brooklyn Urology Research Group
Glioblastoma
Laser Interstitial Thermal Therapy (LITT) and Lomustine (CCNU) for Recurrent Glioblastoma
This is a phase 1 study evaluating the safety and feasibility of laser interstitial thermal therapy (LITT) followed by lomustine (CCNU) for recurrent glioblastoma in adults.
- Trial name
- NCT07145112
- Testing
- Laser interstitial thermal therapy, Lomustine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Davis
Muscle Fatigue Caused by Repetitive Muscle Exercise
Portable Low-Level Laser Therapy for Recovery After a Quadriceps-Dominant Fatiguing Task in Recreational Runners
This randomized, sham-controlled, two-period crossover study evaluated the effects of portable 808-nm low-level laser therapy (LLLT) on acute recovery and running biomechanics following a quadriceps-dominant fatiguing task in…
- Trial name
- NCT07808814
- Testing
- LLLT
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chia Nan University of Pharmacy & Science
Pancreatic Cysts
Diagnosis of Pancreatic Cysts: Endoscopic Ultrasound With Fine Needle Aspiration (EUS/FNA), Direct Visualization, and Confocal Laser-induced Endomicroscopy-A Pilot Study
The purpose of this study is to assess the yield of combination modalities in the diagnosis of pancreatic cysts using EUS/FNA, Fiber optics (direct visualization probe), and prototype needle based confocal laser-induced…
- Trial name
- NCT01447238
- Testing
- Direct visualization and needle based confocal laser-induced endomicroscopy miniprobe
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of California, Irvine
Tattoo Removal
A Clinical Evaluation for Tattoo Removal
Evaluate safety and efficacy with the enlighten laser for tattoo removal.
- Trial name
- NCT02756806
- Testing
- Picosecond Q-switched laser
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Sports Performance, Injury Prevention
Effect of Whole-body Photobiomodulation on Muscular Performance Enhancement.
Introduction: Photobiomodulation therapy (PBMT) is based on the emission of light ranging from red to near-infrared spectra by different devices based on diode lasers or light-emitting diodes.
- Conditions
- Sports Performance, Injury Prevention, Muscle Damage, Musculoskeletal Pain
- Trial name
- WBPME (NCT05989815)
- Testing
- Muscle damage protocol training, Photobiomodulation therapy (PBMT)
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Crohn Disease
AI-enabled Endoscopic Prediction of Post-operative Recurrence in Crohn's Disease
This is a multicentre prospective international observational study. This study aims to introduce a novel multidimensional approach to precision imaging, enabling the identification and stratification of high-risk patients who…
- Trial name
- PROSPER (NCT06505304)
- Testing
- Colonoscopy, Intestinal biopsies, Confocal laser endomicroscopy
- Where
- 15 sites in Belgium, Canada and 4 more
- Volunteers
- 225 people
- Sponsor
- University College Cork
Myopia, Refractive Ametropia
The Impact of 'A Miss Is as Good as a Mile': Is Compensation Necessary for Minimal Ocular Deviation in Myopic Laser Surgery?
The goal of this clinical trial is to evaluate the effect of intraoperative kappa-angle compensation on postoperative visual quality in patients undergoing small incision lenticule extraction (SMILE) using the VisuMax 800…
- Trial name
- NCT07512115
- Testing
- Apply compensation to the Kappa angle., Apply no compensation to the Kappa angle
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Low-level Light Therapy, Cryotherapy
Comparison Between Low-level Laser Therapy, Intracanal Cryotherapy and Their Combination, on Post-endodontic Pain Level
Statement of the problem: Postoperative pain following endodontic treatment is a common complication that might require analgesics for pain relief.
- Trial name
- NCT04006717
- Testing
- Low Level Laser therapy, Intra canal Cryotherapy
- Where
- Egypt
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Misr International University
Capsule Opacification, Ocular Hypertension
Prophylactic Use of Timolol Maleate to Prevent Intraocular Pressure Elevation After Nd:YAG Laser Posterior Capsulotomy
This randomized controlled trial evaluated whether a single drop of 0.5% timolol maleate, administered before neodymium-doped yttrium aluminium garnet (Nd:YAG) laser posterior capsulotomy, reduced the rise in intraocular pressure…
- Trial name
- NCT07729189
- Testing
- Timolol Maleate, No intervention
- Where
- Pakistan
- Volunteers
- 210 people
- Sponsor
- CMH Multan Institute of Medical Sciences
Low Back Pain
Effect of Low Level Laser Versus Interferential Current on Postmenopausal Low Back Pain
This study will be conducted to compare the effect of low-level laser and interferential current on postmenopausal low back pain.
- Trial name
- NCT06586450
- Testing
- Low level laser therapy, Interferential current, Core stability exercise
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
FS-LASIK Surgery Effect on Higher Order Aberrations
Contribution of SA and Coma to The Total Ocular HOA Before and After FS-LASIK Using An Aspheric Ablation Profile
Laser-assisted in situ keratomileusis (LASIK) is the most frequently performed refractive surgery procedure for the correction of myopia, hyperopia, and astigmatism.
- Trial name
- NCT04966806
- Testing
- LASIK refractive surgery
- Where
- Egypt
- Volunteers
- 17 people
- Sponsor
- Kasr El Aini Hospital
Glaucoma
Efficacy of Direct Selective Laser Trabeculoplasty in Clinical Practice in Patients with Glaucoma
Prospective, single-arm, single-center, non-randomized, non-comparative study including naïve patients attending our center diagnosed with glaucoma, who have been recommended treatment with direct selective laser trabeculoplasty…
- Trial name
- NCT06808633
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Clínica Rementería
Tattoos
Clinical Evaluation of 755nm Alexandrite Laser Versus Nanosecond 755nm Alexandrite
Compare the efficacy of the 755nm Alexandrite laser to the nanosecond 755nm Alexandrite laser for the removal of unwanted tattoos using photographic evaluation and histological findings.
- Trial name
- NCT01811017
- Testing
- 755nm Alexandrite Laser
- Where
- United States
- Sponsor
- Cynosure, Inc.
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