Clinical trials: Lens Implantation, Intraocular
Intraocular Lens
Distance and Intermediate Visual Acuity in Patients With Implanted Monofocal Negative Aspheric Intraocular Lens
To get the visual outcomes for distance and intermediate and binocular defocus curve in patients with implanted monofocal intraocular lens Clareon (IOL; model SY60CL; Alcon Vision LLC) at 3 months after the surgery.
- Trial name
- CLAINT (NCT05697978)
- Testing
- Monofocal intraocular lens Clareon (Alcon LLC)
- Where
- 3 sites in Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Cataract
Night Driving Pilot
Pilot study to evaluate usability of Mesotest II for assessment of night driving capacity of pseudo-phakic patients implanted with aspheric monofocal posterior chamber IOL *AT.Smart 46LC.
- Trial name
- NCT00876278
- Testing
- *AT.Smart 46LC
- Where
- Germany
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Postmarket Study of an Intraocular Lens Power Selection System
The purpose of the study was to evaluate the visual acuity outcomes when using the Optiwave Refractive Analysis (ORA) with VerifEye+ and Barrett Toric Calculator for calculating intraocular lens (IOL) power and axis in subjects…
- Trial name
- NCT03579433
- Testing
- ORA with VerifEye+, Alcon Barrett Toric Calculator, Acrysof® IQ Toric IOL
- Where
- 9 sites in United States
- Volunteers
- 124 people
- Sponsor
- Alcon Research
Cataract
Post-Market Clinical Survey of Clareon® IOL AutonoMe™ in Japanese Subjects
This purpose of this survey study is to collect and describe clinical outcomes for the intraocular lens (IOL) delivery performance of Clareon® IOL AutonoMe™ when used in daily practice.
- Trial name
- NCT03824028
- Testing
- Clareon® IOL AutonoMe™ automated preloaded delivery system
- Where
- 3 sites in Japan
- Volunteers
- 384 people
- Sponsor
- Alcon Research
Cataract Surgeries
Comparison of the Concordance Between Digital Marking and Manual Marking for Toric Intraocular Lens Positioning
This cross-sectional comparative study evaluated patients from a single cataract center. In each eye, manual horizontal meridian axis line was marked on the cornea using the manual peripheral corneal marking technique (Horizontal…
- Trial name
- NCT07710963
- Testing
- Verion Digital Marking
- Volunteers
- 100 people
- Sponsor
- Thammasat University
Lenses, Intraocular, Glaucoma Filtration Implants
Visual Function and Patient Satisfaction in Glaucoma or Ocular Hypertensive Patients Undergoing Simultaneous Cataract Surgery and i-Stent Implantation
New extended depth of focus intraocular lenses (IOLs) are being used in a broader spectrum of patients than trifocal IOLs. The purpose of this study is to evaluate visual improvement after cataract surgery in patients with…
- Trial name
- NCT05392738
- Testing
- I-Stent implantation
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Clínica Rementería
Cataract
Cell Ongrowth and Biocompatibility Study of Two Different (Hydrophobic Acrylic) Intraocular Lenses: IOL XY1 vs. IOL XY1A
The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery.
- Trial name
- NCT06708806
- Testing
- cataract surgery
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Cataracts
Clinical Investigation of AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0]
The purpose of this study is to compare the safety and efficacy of an investigational multifocal intraocular lens (IOL) to an FDA-approved monofocal IOL.
- Trial name
- NCT01510717
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0], AcrySof® IQ Monofocal IOL Model SN60WF
- Volunteers
- 409 people
- Sponsor
- Alcon Research
Cataract
Clinical Trial on the Visual Function of Enhanced Monofocal and EDoF Intraocular Lenses
Randomized clinical trial to evaluate the visual performance of enhanced monofocal and extended depth-of-field intraocular lenses
- Trial name
- NCT07715071
- Testing
- Intraocular lens
- Volunteers
- 90 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Cataract
Low-add Multifocal vs. Monofocal IOLs
Compare low-add multifocal IOLs with monofocal IOLs to evaluate if patients in the low-add multifocal IOL group have better unaided distance visual acuity compared to the monofocal group.
- Trial name
- NCT03749161
- Testing
- Low-add multifocal IOL, Monofocal IOL
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Cataract, Astigmatism
Clinical Evaluation of Toric Intraocular Lens
Evaluate efficacy and safety of the toric IOL implanted into aphakic eye with corneal astigmatism after cataract surgery.
- Trial name
- NCT03242486
- Testing
- toric intraocular lens
- Volunteers
- 64 people
- Sponsor
- Nidek Co. LTD.
Cataract
Level of Agreement of Intraocular Lens Power Measurements Between IOLMaster and Verion
Primary objective of this study is to evaluate the level of agreement of two keratometry modules, the IOLMaster and the Verion Reference Unit, in terms of keratometric values and IOL power calculation.
- Trial name
- NCT03876782
- Testing
- IOLMaster, Verion
- Where
- Greece
- Volunteers
- 54 people
- Sponsor
- Democritus University of Thrace
Cataract, Retinitis Pigmentosa (RP)
Impact of Capsular Tension Ring on Intraocular Lens Position in Retinitis Pigmentosa Cataract Patients
This is a self-controlled randomized clinical trial to investigate the effect of capsular tension ring (CTR) implantation on intraocular lens (IOL) position in cataract patients with retinitis pigmentosa(RP).
- Trial name
- NCT07126470
- Testing
- CTR implantation
- Where
- 3 sites in China
- Volunteers
- 88 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataracts Infantile, Subluxation of Lens
Anterior Versus Posterior Artisan Intraocular Lens Fixation in Aphakic Children With Insufficient Capsular Support.
The Artisan lens (Artisan Aphakic, Ophtec BV) is an iris- claw lens designed for implantation in children with insufficient capsular support.
- Conditions
- Cataracts Infantile, Subluxation of Lens, Intraocular Lens Complication, Corneal Endothelial Cell Loss
- Trial name
- NCT06396156
- Testing
- Anterior enclavation, Posterior enclavation
- Where
- 2 sites in Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Cataract, Cataract (Post-operative Cataract Surgery Follow-up)
Evaluation of Visual Outcomes, Complications, and Neuroadaptation Following Bilateral Implantation of enVista Envy Trifocal Intraocular Lenses
The enVista Envy intraocular lens (IOL) manufactured by Bausch + Lomb is a new multifocal intraocular lens based on diffractive optics.
- Trial name
- NCT07696130
- Testing
- cataract surgery
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Pomeranian Medical University Szczecin
Cataract, Lens Opacities
Clinical Investigation of a Monofocal Toric Intra Ocular Lens (IOL) in Cataractous Eyes
This is a Multi-center, single-arm and non-masked study whereby patients undergoing routine cataract surgery be implanted with a hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC (model POD T 49P).
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- PHY2107 (NCT05255029)
- Testing
- POD T 49P implantation experimental
- Where
- 4 sites in Japan
- Volunteers
- 42 people
- Sponsor
- Beaver-Visitec International, Inc.
Aphakia, Postcataract
Clinical Outcomes of Clareon Vivity Intraocular Lens With Mini-Monovision Approach
Purpose is to study the clinical outcomes of Clareon Vivity and Clareon Vivity Toric intraocular lens (IOL) implants in patients who are planning to have cataract surgery in both eyes with a mini-monovision approach.
- Trial name
- NCT05821101
- Testing
- Clareon Vivity and Clareon Vivity Toric IOLs targeted for mini-monovision with dominant eye set at emmetropia and non-dominant eye at -0.50.
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Debbie S. Kuo, MD
Cataract, Uveitis
Safety and Efficacy of a Heparin-Coated Intraocular Lens in Uveitis
To investigate the safety and efficacy of a heparin surface-modified intraocular lens in patients with uveitis undergoing cataract surgery.
- Trial name
- NCT00000119
- Testing
- Heparin Surface-Modified Intraocular Lens
- Where
- United States
- Sponsor
- National Eye Institute (NEI)
Cataract, Presbyopia
Comparative Analysis of the Visual Performance and Patient Satisfaction After Cataract Surgery With Implantation of a Medicontur Monofocal (877PAY) or a Medicontur Extended Depth of Focus (877PEY) IOL
The purpose of this multi-center, prospective, randomized, comparative clinical investigation was to evaluate and compare the visual performance at far, intermediate and near distances, the presence of photopic phenomena and…
- Conditions
- Cataract, Presbyopia, Ametropia
- Trial name
- NCT06642779
- Testing
- VFQ- 25 (Visual Function Questionnaire), Optical Biometry, Slit lamps / Fundoscopy / Biomicroscopy
- Where
- 3 sites in Hungary
- Volunteers
- 64 people
- Sponsor
- Medicontur Medical Engineering Ltd
Cataract
Pseudophakic Eyes With Presbyopia-correcting IOLs: OCT Biometry and Pyramid Aberrometry
To correlate ocular morphology from anterior segment OCT and pyramid wavefront sensing in order to comprehensively analyze pseudophakic in vivo image quality of presbyopia-correcting IOLs in cataract patients.
- Trial name
- NCT07436247
- Testing
- Osiris-T Pyramid Wavefront Sensor - (CSO, Italy)
- Where
- 2 sites in Austria
- Volunteers
- 80 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA