Clinical trials: Lenses
Cataract
Post-Approval Study of the Tecnis® Toric IOL
This study is a prospective, multicenter, bilateral, non-randomized, open-label, comparative clinical study conducted at up to 80 sites in the USA.
- Trial name
- NCT02566083
- Testing
- non-toric intraocular lens, toric intraocular lens
- Where
- 44 sites in United States
- Volunteers
- 365 people
- Sponsor
- Abbott Medical Optics
Myopia
Clinical Evaluation of an Investigational Soft Contact Lens
The purpose of this 4-week dispensing trial is to evaluate and compare an investigational soft contact lens worn on a daily disposable basis with three other soft contact lenses also worn on a daily disposable basis.
- Trial name
- NCT01254747
- Testing
- Delefilcon A contact lens, Lotrafilcon B contact lens (O2 OPTIX, AIR OPTIX), Nelfilcon A contact lens (DAILIES AquaComfort Plus)
- Where
- 2 sites in United States, Germany
- Volunteers
- 130 people
- Sponsor
- CIBA VISION
Cataract
AMO's Tecnis™ Multifocal Intraocular Lenses (Tecnis MF), Alcon's ReStor Multifocal IOL
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR IOLs Six months post cataract surgery.
- Trial name
- NCT01278420
- Testing
- Tecnis MF, ReSTOR
- Where
- 6 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Visual Acuity
Clinical Study of Approved and Investigational Contact Lenses
This is a multi-site, 5-visit, double-masked, dispensing study comparing an investigational contact lens with currently-marketed contact lenses.
- Trial name
- NCT02708524
- Testing
- Senofilcon C Contact Lens, Comfilcon A Contact Lens, Lotrafilcon B Contact Lens
- Where
- 18 sites in United States
- Volunteers
- 554 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract, Presbyopia
Comparative Analysis of the Visual Performance and Patient Satisfaction After Cataract Surgery With Implantation of a Medicontur Monofocal (877PAY) or a Medicontur Extended Depth of Focus (877PEY) IOL
The purpose of this multi-center, prospective, randomized, comparative clinical investigation was to evaluate and compare the visual performance at far, intermediate and near distances, the presence of photopic phenomena and…
- Conditions
- Cataract, Presbyopia, Ametropia
- Trial name
- NCT06642779
- Testing
- VFQ- 25 (Visual Function Questionnaire), Optical Biometry, Slit lamps / Fundoscopy / Biomicroscopy
- Where
- 3 sites in Hungary
- Volunteers
- 64 people
- Sponsor
- Medicontur Medical Engineering Ltd
Myopia
Daily Disposable Dispensing Clinical Trial of Test Lens Against Stenfilcon A Lens
The purpose of this study is to investigate the overall clinical performance of the test daily disposable stenfilcon A lens with solution additive (test) compared to the stenfilcon A lens (control).
- Trial name
- NCT03024970
- Testing
- stenfilcon A lens with solution additive (test), stenfilcon A lens (control)
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract
A Clinical Study of the ACRYSOF® IQ Extended Depth of Focus Intraocular Lens (IOL)
The purpose of the study is to demonstrate the safety and performance of ACRYSOF IQ extended depth of focus (EDF) intraocular lens (IOL) at Month 6.
- Trial name
- NCT03274986
- Testing
- ACRYSOF® IQ Extended Depth of Focus IOL, ACRYSOF® IQ Monofocal IOL, Cataract surgery
- Where
- 11 sites in United States
- Volunteers
- 242 people
- Sponsor
- Alcon Research
Cataract
Clinical Investigation of the AcrySof® IQ PanOptix™ IOL
The purpose of this study is to evaluate the effectiveness and safety of the AcrySof® IQ PanOptix™ Intraocular Lens (IOL) Model TFNT00 when implanted to replace the natural lens following cataract removal.
- Trial name
- NCT03090256
- Testing
- AcrySof® IQ PanOptix™ IOL
- Where
- 2 sites in Japan
- Volunteers
- 76 people
- Sponsor
- Alcon Research
Aphakia, Cataract
Comparison of the Hoya Surgical Optics (HSO) iSert 251 Posterior Chamber Aspheric Aphakic Intraocular Lens to Historical / Literature Controls.
The purpose of this multi-center clinical trail is to determine the safety and efficacy of the iSert 251 for the correction of aphakia.
- Trial name
- NCT01292629
- Testing
- iSert 251 intraocular lens
- Where
- 5 sites in United States
- Volunteers
- 125 people
- Sponsor
- Hoya Surgical Optics, Inc.
Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression.
This is a mono-centre, prospective, one-arm, unmask clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation compared to a single vision spectacle lens from…
- Trial name
- NCT05534022
- Testing
- Test myopia control lenses (BSL)
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Essilor International
Dry Eye Syndromes
Clinical Trial to Evaluate the Symptoms in Symptomatic Contact Lens Wearers Following Application of Intranasal Tear Neurostimulator Versus Control
This study will evaluate the increase in comfort and comfortable contact lens (CL) wear time associated with application of TrueTear (active intranasal neurostimulation) compared with application of TrueTear sham control…
- Trial name
- NCT03325673
- Testing
- TrueTear
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Allergan
Ametropia, Myopia
Clinical Investigation of Proclear® 1 Day and MyDay® Sphere Contact Lenses
The aim of this study is to evaluate and compare the performance of two soft contact lenses.
- Trial name
- NCT07104773
- Testing
- Control Lens (omafilcon A), Test Lens (stenfilcon A)
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Lens Wearers
The purpose of this trial is to evaluate the extent to which symptoms improve in symptomatic contact lens wearers when fit with one of 5 different daily disposable contact lenses.
- Trial name
- NCT00953407
- Testing
- Nelfilcon A contact lens, Narafilcon A contact lens, Etafilcon A contact lens
- Volunteers
- 128 people
- Sponsor
- CIBA VISION
Refractive Error - Myopia Bilateral
Clinical Performance of 59% Hioxifilcon A vs. Marketed Hydrogel Contact Lenses in Habitual Hydrogel Wearers
The study will compare the short-term clinical performance and wearer and practitioner acceptability of a new-to-market spherical daily disposable (DD) hydrogel soft contact lens to a currently marketed spherical DD hydrogel soft…
- Trial name
- NCT04986644
- Testing
- Hioxifilcon A standard hydrogel contact lens with Hyaluronic Acid (HA)
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vision Service Plan
Myopia, Astigmatism
Study of an Implantable Collamer Lens (ICL)
A prospective, open-labeled, single-site study of an implantable collamer lens (ICL) for the correction/reduction of myopia with or without astigmatism.
- Trial name
- NCT07791381
- Testing
- Implantable collamer lens (ICL)
- Volunteers
- 10 people
- Sponsor
- Staar Surgical Company
Myopia
Post-market Follow Up Study on Paragon CRT® 100 (Paflufocon D)
The main objective of this post market clinical study is to evaluate the effectiveness and safety of the Paragon CRT®100 Contact Lens.
- Trial name
- NCT04187599
- Testing
- Paragon CRT®100 Contact Lens
- Where
- 4 sites in China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Cataracts
Nepafenac 0.1% Eye Drops, Suspension Compared to Ketorolac Trometamol 0.5% Eye Drops, Solution and Placebo
To evaluate the safety and efficacy of Nepafenac 1 mg/ml Eye Drops, Suspension, compared to Placebo and Ketorolac Trometamol 5 mg/ml Eye Drops, Solution for the prevention and treatment of ocular inflammation and ocular pain…
- Trial name
- NCT00405730
- Testing
- Nepafenac 1mg/ml eye drops, suspension, Ketorolac Trometamol 5 mg/ml eye drops, solution, Nepafenac vehicle eye drops
- Where
- France
- Volunteers
- 227 people
- Sponsor
- Alcon Research
Ametropia, Myopia
Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Toric Contact Lenses
The primary objective of this study is to evaluate the axis orientation of LID226397 toric contact lenses.
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT05959200
- Testing
- Serafilcon A toric contact lenses, Senofilcon A toric contact lenses, CLEAR CARE
- Where
- 7 sites in United States
- Volunteers
- 92 people
- Sponsor
- Alcon Research
Cataract
Surveillance of Ocular Surface Flora (SURFACE)
Topical fluoroquinolones (FQs) have achieved widespread use in ophthalmology for both the treatment and prophylaxis of ocular infections.
- Trial name
- NCT00621933
- Where
- United States
- Volunteers
- 399 people
- Sponsor
- Allergan
Myopia, Cornea
Euclid Phoenix Lens Design Trial
The "first fit" success rate of the current Euclid orthokeratology "MAX" lens design will be compared to that of the new Euclid orthokeratology MAX "Phoenix" lens design in 30 children.
- Trial name
- NCT06389916
- Testing
- Euclid orthokeratology MAX (current design), Euclid orthokeratology MAX Phoenix (new design)
- Where
- 5 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Euclid Systems Corporation
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