Clinical trials: Life Experiences
Early Life Adversity, Chronic Stress
Health Experiences & Early Life Disadvantages
Growing up in a low-income household has been shown to increase risk for, and susceptibility to many illnesses.The purpose of the study is to test an affective intervention for reversing biological risk factors, as related to…
- Trial name
- HEELD (NCT02400593)
- Testing
- Meditation Workshop
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Sexual Dysfunction, Stress Incontinence
A Study to Measure the Degree and Effectiveness of the Various vSculpt Operating Modes
A pilot study to determine the degree and effectiveness of the various modes of vSculpt, an over-the-counter "OTC" medical device, on enhanced genital blood flow and improvement in quality of life in menopausal women who suffer…
- Trial name
- NCT02856490
- Testing
- vSculpt, InTone
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Joylux, Inc.
Dementia, Neuro-Degenerative Disease
Lived Experience Narratives in Dementia
The Lived Experience Narratives in Dementia (LEND) research programme involves five work packages (WP). WP1 explores how people living with dementia use narratives and how narratives can impact them.
- Conditions
- Dementia, Neuro-Degenerative Disease, Alzheimer Disease, Caregiver Burden
- Trial name
- LEND (NCT07757178)
- Testing
- Online LEND Intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Grief
A Finding Balance Writing Intervention for Older Bereaved Caregivers
The overall purpose of this study is to develop and pilot-test a theory-based psychosocial supportive "finding balance" intervention for older, bereaved spousal caregivers of a palliative cancer patient.
- Trial name
- NCT01416779
- Testing
- Writing Intervention
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Hearing Loss, Bilateral or Unilateral
How Parents, Children, and Clinicians Experience Digital Health Tools in Pediatric Audiology
The goal of this observational study is to understand how children with hearing loss, their parents, and health care providers experience digital health questionnaires that are completed before audiology follow-up appointments.
- Trial name
- NCT06943976
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Multiple Myeloma
Patient and Care Partner Experiences Living With Multiple Myeloma (PaCE-MM)
This research study is explore the impact over time of multiple myeloma and its associated treatments on the physical and cognitive function and quality of life of patients and their care partners and how these impacts affect the…
- Trial name
- PaCE-MM (NCT05276622)
- Testing
- Comprehensive Geriatric Assessment, Qualitative patient-care partner interviews, Surveys on well-being and function
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Experience, Life, Dialysis
What Does the Patient Experience Represent for Patients and Caregivers in Dialysis?
The primary objective of this work is to describe the vision, representations, and beliefs of professionals and patients regarding the role and place of the user during their care journey at the Calydial renal health facility.
- Conditions
- Experience, Life, Dialysis, Patient Engagement, Patient Participation
- Trial name
- EnquêteXP (NCT06529887)
- Where
- 4 sites in France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Calydial
Periodontitis
Effect of Periodontitis Treatment on Quality of Life and Experiences of Fear, Anxiety and Pain
There are different protocols to treat gum diseases. One relevant differential aspect is related to time. There are protocols that usually takes one to two months to be completed while other are completed within 24 hours.
- Trial name
- NCT02409966
- Testing
- Quadrant-wise scaling, Full-mouth 24-hour scaling
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Taubate
Life Experiences
Sleep Health, Workplace Stress and Wellbeing in NUS Staff: the NUS1000 Staff Edition Study
Workplace stress can significantly affect workers sleep, physical health and mental wellbeing. Recognizing and characterizing obstacles to healthy sleep patterns in office workers can help identify targets for corporate…
- Trial name
- NUS1000SE (NCT06594549)
- Where
- Singapore
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Overweight and Obesity
An App-based Mindfulness Intervention for Sexual Minority Women With a History of Early Life Adversities (ELA)
Sexual minority women (SMW) in mid-age are at significantly higher risk for obesity, which is associated with greater vulnerability to cardiovascular disease, diabetes, cancer, and mortality.
- Trial name
- NCT05201391
- Testing
- "Eat Right Now" (ERN) mobile application
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brown University
Breast Reconstruction, Patient Education
Educational Session To Optimize Patient's Breast Reconstruction Experience at McMaster
This pilot study uses a randomized controlled trial design to introduce an educational session for breast reconstruction patients. Participants will be randomly assigned to the (1) control group or the (2) experimental group.
- Trial name
- RESTORE (NCT03743753)
- Testing
- Experimental
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Adverse Childhood Experience, Endothelial Function (FMD)
Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity
Adverse childhood experiences (ACEs) represent highly stressful events in the first 18 years of life that include abuse, neglect, and household and community-level dysfunction.
- Conditions
- Adverse Childhood Experience, Endothelial Function (FMD), Endothelial Injury, Mitochondrial Function
- Trial name
- PROMISE (NCT07244809)
- Testing
- Mitoquinone mesylate (MitoQ)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Critical Illness, Near-Death Experience
Incidence of Episodes of (Dis)Connected Consciousness Among Emergency Patients Admitted in the Resuscitation Room
This observational study aims to describe the incidence of episodes of disconnected consciousness (including near-death experience (NDE)) and episodes of connected consciousness in patients admitted to the resuscitation room, who…
- Conditions
- Critical Illness, Near-Death Experience, Consciousness, Loss of, Quality of Life
- Trial name
- NCT06362525
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Liege
Haematological Malignancy, Leukemia, Acute
Rehabilitation Needs of the Malaysian Haematological Cancer Survivors
Many cancers are being treated more effectively nowadays due to the raised awareness and early detection as well as advancement in researches and technology.
- Conditions
- Haematological Malignancy, Leukemia, Acute, Lymphoma, Myeloma Multiple
- Trial name
- NCT04236063
- Testing
- WHODAS 2.0 Questionnaire
- Where
- Malaysia
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Stress, Psychological Stress
Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity
The aim of the Everyday Moments of Mindfulness (EMMI) study is to test whether brief mindfulness-based practices will improve daily psychological stress responses in women (age 30-60) who report a history of early life adversity.
- Conditions
- Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms
- Trial name
- EMMI (NCT04606199)
- Testing
- Mindfulness-based intervention, up to 5 minutes 0-3 times/day
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sleep Disturbance
Bonafide Sleep Supplement for Menopausal Women With Sleep Complaints
This open-label study was designed to evaluate whether a daily dietary sleep supplement could improve sleep quality and related daytime well-being in menopausal women aged 40 to 65 with sleep complaints.
- Trial name
- NCT07839312
- Testing
- S-Adenosyl Methionine (SAMe), Propyl Gallate, Gamma-Aminobutyric Acid (GABA), L-Theanine, and Magnesium Glycinate
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Bonafide Health
Fatigue Symptom, Fatigue Intensity
Monitoring Fatigue In Daily Life In Adults With Cerebral Palsy or Acquired Brain Injury
The goal of this observational study is to learn about levels and patterns of fatigue in adults with cerebral palsy (CP) and acquired brain injury (ABI) in daily life.
- Conditions
- Fatigue Symptom, Fatigue Intensity, Cerebral Palsy (CP), Acquired Brain Injury Including Stroke
- Trial name
- NCT07135791
- Testing
- Real-time monitoring
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Experience, Life, Stress
The Use of the Diary in Neonatal Pathology: a Mixed-method Study for Collecting and Analyzing the Experience of Parents and Health Care Personnel.
The study is mixed-methods (qualitative + quantitative observational cross-sectional) and the aims are to explore the use of diaries by parents of newborns admitted to Neonatal Pathology and to describe some variables related to…
- Conditions
- Experience, Life, Stress, Depression, Postpartum, Support, Family
- Trial name
- DiaPaNeo (NCT06316193)
- Testing
- Diary
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- IRCCS Ospedale San Raffaele
Cardiac Arrest (CA)
The Effect of Virtual Reality-Assisted Escape Room Experience
The aim of this study is to improve associate degree Dialysis Program students' Basic Life Support (BLS) knowledge and skills through a virtual reality (VR)-supported escape room intervention.
- Trial name
- VR (NCT07846124)
- Testing
- Virtual Reality-Supported Escape Room Training, Control Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Adverse Childhood Experiences, Housing Problems
Evaluation of the Building Healthy Life Skills Program
The goal of this intervention trial is to learn test whether participation in the Building Health Life Skills Program leads to improvements in psychological well-being and stress management skills for people who are experiencing…
- Conditions
- Adverse Childhood Experiences, Housing Problems, Emotion Regulation
- Trial name
- NCT05611060
- Testing
- Building Healthy Life Skills Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Merced