Clinical trials: Light
Meibomian Gland Dysfunction
Efficacy and Safety of Meibomian Gland Dysfunction and Dry Eye With an LED Blue Treatment Device
This study will test the efficacy and safety of application of LED light to meibomian glands in upper and lower eyelids in eyes of patients suffering with meibomian gland disease.
- Trial name
- NCT03788486
- Testing
- 2-3 Joule LED blue light device
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Toyos Clinic
Uremic; Toxemia
A Comparison of Protein-bound and Large Molecular Weight Uremic Toxin Removals With Novel Super High-flux Dialyzer Between Hemodialysis and High Volume Online HDF Modalities
The goal of this prospective, randomized, crossover study is to study about using super high-flux dialyzer in the chronic hemodialysis patients.
- Trial name
- NCT06567483
- Testing
- ELISIO21HX
- Where
- Thailand
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Major Depression
The Effect of Exercise on Depressive Symptoms in Unmedicated Patients
This trial investigates the biological effect of exercise training on depression. Participants will randomly be allocated to either a aerobic exercise group performing exercise on stationary bikes or a group performing low-impact…
- Trial name
- DEMOII (NCT00695552)
- Testing
- Aerobic exercise, Low impact exercise
- Where
- Denmark
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Optical Properties of Laminate Veneers
Optical Properties of Light Cured Luting Agent on Laminate Veneer
The aim of this randomized clinical trial is to evaluate the influence of luting agent, thickness and color of laminate veneers (LVs) and color of dental substrate on the optical properties of LVs.
- Trial name
- NCT02464540
- Testing
- Laminate veneers luted with light-cured resin cement, Laminate veneers luted with light-cured flowable composite
- Where
- Brazil
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Hydration Status, Substrate Metabolism During Exercise
The Effect of Hydration Status on Substrate Oxidation at Rest and During Light and Moderate Exercise
Metabolic flexibility is the ability to properly switch between fat and carbohydrate stores to use for energy under different conditions (rest, feeding, exercise).
- Trial name
- NCT07298863
- Testing
- Part 1 - Exercise Trial, Part 1 - Experimental Trial, Part 2 - Oral Glucose Tolerance Test
- Where
- 2 sites in United States, Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Concussion, Mild, Post-Concussion Symptoms
Effects of Bright Light Therapy in Mild Traumatic Brain Injury
Mild traumatic brain injuries (mTBI) or "concussions" are an increasingly prevalent injury in our society. Patients with post-concussion syndrome have been shown to have deficits on tests of short term memory, divided attention…
- Conditions
- Concussion, Mild, Post-Concussion Symptoms, Sleep Problems
- Trial name
- NCT01747811
- Testing
- wavelength-1 bright light, wavelength-2 bright light
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Psoriasis
Resolvin D1 in Psoriasis Before and After Narrowband UVB Phototherapy
Assessment of tissue level of resolvin D1 in psoriasis in comparison to its level in healthy controls in order to verify its role in the pathogenesis of psoriasis.
- Trial name
- NCT03483311
- Testing
- skin biopsy before and after NB-UVB phototherapy
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Cancer
Effects of Bright Light on Co-occurring Cancer-related Symptoms in Breast Cancer Survivors
This study will implement therapeutic bright light that is tailored to the individual's circadian typology and will estimate its effects on circadian rhythms, 4 common cancer-associated symptoms, and impact on quality of life in…
- Trial name
- NCT03304587
- Testing
- Polysomnography (PSG), Rectal thermistor 400 Series, Bright blue-green light
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Non-visual Effects of Light
Effect of Lighting Supplementation on Daytime Cognition
The aim of the study is to examine the efficacy of supplementing sub-optimal ambient room lighting with a task lamp on working memory and procedural learning.
- Trial name
- NCT04745312
- Testing
- Visible light
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pregnant Women, Stress
Effect of Light Color on Stress, Anxiety, and Psychological Well-being During Nonstress Test in Pregnant Women at Risk
Purpose of the research: To determine the effect of light color on stress, anxiety, and psychological well-being during the Nonstress Test in at-risk pregnant women.
- Conditions
- Pregnant Women, Stress, Light
- Trial name
- NCT06736873
- Testing
- Light intervention
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Osmaniye Korkut Ata University
COVID-19
Platelet Aggregation in COVID-19 Patients
Context: Hypercoagulable state associated with COVID-19 is one of the pathologic events that noticed in different waves of COVID-19 pandemics and leads to serious consequences in mortality and morbidity Aim: To evaluate platelet…
- Trial name
- NCT06097429
- Testing
- blood sample for platelet aggregation
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Phototherapy
PBMT on Muscular Performance and Recovery in Different Time-points
Recent studies with photobiomodulation therapy (PBMT) have shown positive results delaying skeletal muscle fatigue and improving the status of biochemical markers related to skeletal muscle damage when these therapies were…
- Trial name
- NCT03420391
- Testing
- Photobiomodulation Therapy (PBMT)
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Anorexia Nervosa, Anorexia Nervosa Restricting Type
Novel Targetable BIOmarkers in ANorexia NervosA
The overall aim of this present study is to evaluate Growth Differentiation Factor-15 (GDF-15) and inflammatory cytokines as a possible novel and readily treatable target for the successful therapy of Anorexia Nervosa (AN).
- Trial name
- BIOANNA (NCT05885724)
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Sedentary Lifestyle, Risk Factor, Cardiovascular
Assessing the Effects Of Treadmill On LPA, Sitting Time, and Cardiovascular Risk
The purpose of this study is to: 1. Evaluate the relative efficacy of a treadmill desk intervention on light physical activity and sitting behaviors at work over four weeks; 2.
- Trial name
- NCT03236597
- Testing
- Treadmill desk
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Refractory Epilepsy
Effect of Blue Light on Vagus Nerve Stimulation in Patients With Refractory Epilepsy
Vagus nerve stimulation (VNS) is an adjunctive treatment for refractory epilepsy. Although widely used, there is still a substantial number of patients with insufficient response.
- Trial name
- BLUELIGHTVNS (NCT06304389)
- Testing
- electroencephalography, electrocardiogram, pupillometry, evoked potentials, light administration, transcutaneous vagus nerve stimulation, electroencephalography, pupillometry, electrocardiogram, light administration
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Nociceptive Pain, Pupillary Light Reflex Lost
Clinical Trial Using Pupillometry to Measure Nociception in Healthy Volunteers.
Pupillometry has been used in healthy volunteers to investigate the usefulness of the pupil light reflex as an indicator of pain intensity on pressure as a nociceptive stimulus.
- Conditions
- Nociceptive Pain, Pupillary Light Reflex Lost, Healthy, Pain, Procedural
- Trial name
- NCT04864340
- Testing
- CE marked medical device, Algometer, Comparator
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Neonatal Jaundice
Intermountain Inpatient Bilirubin Decision Accuracy Study Using Smartphone-based Measurements by Picterus Jaundice Pro
The goal of this project is to evaluate the performance of Picterus Jaundice Pro in an American population, including preterm and term newborns and pre- and post- phototherapy.
- Trial name
- NCT06329843
- Testing
- Picterus Jaundice Pro (JP)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Picterus AS
Amyloidosis, AL Amyloidosis
BE.Amycon Biobank & Data Registry UZ Leuven
The goal of this study is to collect and store human body material (HBM) of patients with amyloidosis in a biobank "BE.Amycon biobank" for future research and to collect clinical data of patients with amyloidosis in a database…
- Conditions
- Amyloidosis, AL Amyloidosis, Amyloidosis Cardiac
- Trial name
- NCT07172243
- Where
- 2 sites in Belgium
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Photodermatoses
The Effects of Visible Light on the Skin After Administration of Oral Polypodium Leucotomos
Polypodium Leucotomos Extract (PLE) is a tropical fern that has antioxidative, photoprotective, chemoprotective, anti-inflammatory, and immunomodulatory properties.
- Trial name
- NCT02904798
- Testing
- Polypodium Leucotomos
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Idiopathic Guttate Hypomelanosis
Excimer Light Treatment for Idiopathic Guttate Hypomelanosis: A Pilot Study
This pilot study will consist of 10 adult subjects with symmetric idiopathic guttate hypomelanosis on the lower legs. Subjects will be randomized to which extremity (right or left) will be treated.
- Trial name
- NCT01956435
- Testing
- Excimer Light Treatment
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Seton Healthcare Family