Clinical trials: Light Therapy
COVID-19
Platelet Aggregation in COVID-19 Patients
Context: Hypercoagulable state associated with COVID-19 is one of the pathologic events that noticed in different waves of COVID-19 pandemics and leads to serious consequences in mortality and morbidity Aim: To evaluate platelet…
- Trial name
- NCT06097429
- Testing
- blood sample for platelet aggregation
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Phototherapy
PBMT on Muscular Performance and Recovery in Different Time-points
Recent studies with photobiomodulation therapy (PBMT) have shown positive results delaying skeletal muscle fatigue and improving the status of biochemical markers related to skeletal muscle damage when these therapies were…
- Trial name
- NCT03420391
- Testing
- Photobiomodulation Therapy (PBMT)
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Anorexia Nervosa, Anorexia Nervosa Restricting Type
Novel Targetable BIOmarkers in ANorexia NervosA
The overall aim of this present study is to evaluate Growth Differentiation Factor-15 (GDF-15) and inflammatory cytokines as a possible novel and readily treatable target for the successful therapy of Anorexia Nervosa (AN).
- Trial name
- BIOANNA (NCT05885724)
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Sedentary Lifestyle, Risk Factor, Cardiovascular
Assessing the Effects Of Treadmill On LPA, Sitting Time, and Cardiovascular Risk
The purpose of this study is to: 1. Evaluate the relative efficacy of a treadmill desk intervention on light physical activity and sitting behaviors at work over four weeks; 2.
- Trial name
- NCT03236597
- Testing
- Treadmill desk
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Refractory Epilepsy
Effect of Blue Light on Vagus Nerve Stimulation in Patients With Refractory Epilepsy
Vagus nerve stimulation (VNS) is an adjunctive treatment for refractory epilepsy. Although widely used, there is still a substantial number of patients with insufficient response.
- Trial name
- BLUELIGHTVNS (NCT06304389)
- Testing
- electroencephalography, electrocardiogram, pupillometry, evoked potentials, light administration, transcutaneous vagus nerve stimulation, electroencephalography, pupillometry, electrocardiogram, light administration
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Nociceptive Pain, Pupillary Light Reflex Lost
Clinical Trial Using Pupillometry to Measure Nociception in Healthy Volunteers.
Pupillometry has been used in healthy volunteers to investigate the usefulness of the pupil light reflex as an indicator of pain intensity on pressure as a nociceptive stimulus.
- Conditions
- Nociceptive Pain, Pupillary Light Reflex Lost, Healthy, Pain, Procedural
- Trial name
- NCT04864340
- Testing
- CE marked medical device, Algometer, Comparator
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Amyloidosis, AL Amyloidosis
BE.Amycon Biobank & Data Registry UZ Leuven
The goal of this study is to collect and store human body material (HBM) of patients with amyloidosis in a biobank "BE.Amycon biobank" for future research and to collect clinical data of patients with amyloidosis in a database…
- Conditions
- Amyloidosis, AL Amyloidosis, Amyloidosis Cardiac
- Trial name
- NCT07172243
- Where
- 2 sites in Belgium
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Photodermatoses
The Effects of Visible Light on the Skin After Administration of Oral Polypodium Leucotomos
Polypodium Leucotomos Extract (PLE) is a tropical fern that has antioxidative, photoprotective, chemoprotective, anti-inflammatory, and immunomodulatory properties.
- Trial name
- NCT02904798
- Testing
- Polypodium Leucotomos
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Idiopathic Guttate Hypomelanosis
Excimer Light Treatment for Idiopathic Guttate Hypomelanosis: A Pilot Study
This pilot study will consist of 10 adult subjects with symmetric idiopathic guttate hypomelanosis on the lower legs. Subjects will be randomized to which extremity (right or left) will be treated.
- Trial name
- NCT01956435
- Testing
- Excimer Light Treatment
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Seton Healthcare Family
Emergence Delirium, Anesthesia Emergence Delirium
Effect of Monochromatic Light on Incidence of Emergence Delirium in Children
Emergence delirium/emergence agitation (ED/EA) is a behavioral phenomenon of unclear etiology consisting of short lived behavioral changes that can be both traumatic to families and pose a safety risk to patients and staff.
- Trial name
- NCT03285243
- Testing
- Monochromatic blue light
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Vitamin D Deficiency, Vitamin D Insufficiency
Evaluating the Effect of SOLIUS UV Light Source in Improving Vitamin D Status
The aim of this study is to evaluate the safety and effectiveness of the SOLIUS System in improving serum levels of 25-hydroxyvitamin D in vitamin D deficient/ insufficient adults of various skin types.
- Trial name
- NCT04780776
- Testing
- UVB treatment
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Boston University
Bronchiolitis
Pneumacare SLP Validation in Infants and in Clinical Bronchiolitis
A cohort observational study to characterise baseline Structured Light Plethysmography (SLP) outputs in infants with bronchiolitis and examine response to treatment using the Thora3DiTM
- Trial name
- NCT02881632
- Testing
- Structured Light Plethysmography (SLP) - Pneumscan
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospitals of North Midlands NHS Trust
Tooth Bleaching, Dentin Sensitivity
In-office Bleaching Using a Violet Light
The objective of this clinical study is to evaluate the effect of the whitening treatment performed with the violet LED light (405-410 nm), with or without a bleaching gel, on the tooth color changes (immediate and long-term)…
- Trial name
- NCT03207204
- Testing
- 35% Hydrogen peroxide bleaching, 30% Carbamide peroxide bleaching, Violet LED bleaching 1
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Healthy, Circadian Rhythm
Effects of Different Colors of Light on Human Physiology
This study will determine which color of light is most effective in stimulating a range of biological functions in humans including activation of sleep-wake regulatory system (alertness, performance, microsleeps, brain activity)…
- Trial name
- NCT00200863
- Testing
- Monochromatic visible light exposure
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Acne
The Comparative Efficacy of an Over the Counter Light Therapy Mask vs Over the Counter Topical Benzoyl Peroxide 2.5% and Used in Combination With Over the Counter Adapalene Gel 0.1% for Mild to Moderate Acne
This is a single-center prospective study of two standard-of-care treatments to evaluate the efficacy of the Neutrogena® Light Therapy Acne Mask an Over the Counter (OTC) Blue/Red light LED mask, as compared to the combination of…
- Trial name
- NCT03650881
- Testing
- Neutrogena ® Light Therapy Acne Mask (MASK), Topical OTC benzoyl peroxide 2.5% gel and OTC adapalene
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Sleep Initiation and Maintenance Disorders
Light Treatment for Sleep/Wake Disturbances in Alzheimer's Disease
The aim of this study is to demonstrate the efficacy of timed exposure to bright light for the treatment of disturbed nighttime sleep and daytime wake in community-dwelling dementia patients and their caregivers, and to determine…
- Trial name
- NCT00946530
- Testing
- Bright light, Control
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Stanford University
Circadian Rhythms
Real-World Use of an iPad-Based Light Therapy App, With Optional Biomarker Collection
This study looks at how adults use an iPad-based light app in everyday life. Light is the main signal that sets the body's internal clock, which controls daily rhythms in sleep, alertness, and many other body systems.
- Trial name
- NCT07744711
- Testing
- Circadian OS iPad-based light app
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Circadian OS, Inc
Jumper's Knee
Effect of Two Different Modes of Polarized Polychromatic Non-coherent Light Therapy on Jumper's Knee
The purposes of this study are: 1. To examine the combined effects of Yellow CPPNLT and conventional treatment on pain intensity, pain pressure threshold, functional disability, and muscle strength in athletic jumper knee. 2.
- Trial name
- NCT06306664
- Testing
- Bioptron
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cardiovascular Diseases
The Effects of Unfiltered (Turkish) Coffee Consumption on Cardiovascular Risk Parameters
Purpose/Objective: The aim of this study is to investigate the impact of boiled unfiltered (Turkish) coffee consumption on the plasma cardiovascular risk parameters of healthy subjects.
- Trial name
- NCT03495336
- Testing
- coffee abstention phase, LR Coffee consumption, DR Coffee consumption
- Where
- Cyprus
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Social Perception in Parkinson's Disease
Brain Mechanisms of Social Perception in Parkinson's Disease
Social cognition is a complex process that enables humans to interpret social information and behave appropriately in a social environment.
- Trial name
- Park Social (NCT06884722)
- Testing
- Behavioral task of social perception (stage 1), Functional magnetic resonance imaging: 3 Tesla magnetic resonance imaging (stage 2), Neurological and neuropsychological assessments
- Where
- France
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon