Clinical trials: Long Term Results
Allergic Rhinitis, Asthma
Comparative Real World Effectiveness of SQ Sublingual Immunotherapy (SLIT)-Tablets vs. Controls in Allergic Rhinitis and Asthma
To assess the impact of SQ SLIT-tablets (SQ Grass SLIT-tablet and SQ HDM SLIT-tablet) in Danish and Swedish allergic rhinitis (AR) patients, with or without asthma, between 2007-2020.
- Conditions
- Allergic Rhinitis, Asthma, Allergy
- Trial name
- RELY (NCT05476484)
- Testing
- SQ SLIT-tablet
- Where
- Denmark
- Volunteers
- 46,196 people
- Sponsor
- ALK-Abelló A/S
Respiratory Distress Syndrome, Adult
Long-Term Results in Mechanically Ventilated Individuals With Acute Lung Injury/Acute Respiratory Distress Syndrome
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a severe lung condition that causes respiratory failure. Individuals with ALI/ARDS often require the use of a respirator or artificial breathing machine, known…
- Trial name
- NCT00300248
- Where
- 4 sites in United States
- Volunteers
- 520 people
- Sponsor
- Johns Hopkins University
Migraine
Chronic Pain and Conditioned Pain Modulation After on Line-behavioral Approach
Chronic pain is a disabling condition associated with progressive changes and decline in psychological wellbeing. According with a modern conceptualization, pain has to be considered a biopsychosocial disorder where biological…
- Trial name
- Be-Home-Pain (NCT04859374)
- Testing
- Mindfullness, treatment as usual (TAU) (pharmacological)
- Volunteers
- 35 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Epilepsy
Comparison of Quality of Life and Changes Experienced by Patients After Epilepsy Surgery
Epilepsy is one of the most common chronic neurological diseases. According to data from the World Health Organization (WHO), it affects 0.5 to 1% of the population, or around 70 million people world-wide and around 600,000 in…
- Trial name
- EPICHANGE (NCT06035965)
- Testing
- Epilepsy Surgery Satisfaction Questionnaire (ESSQ-19), Quality of Life in Epilepsy Inventory (QOLIE-31), Generalized Anxiety Disorder 7 (GAD7)
- Where
- France
- Volunteers
- 151 people
- Sponsor
- University Hospital, Toulouse
Quality of Life
Quality of Life Results After Laparoscopic Fundoplication.
The present study focuses on determining aspects of satisfaction and quality of life of patients that underwent laparoscopic Nissen fundoplication with or without short gastric vessel division (SGVD) and long-term differences.
- Trial name
- NCT04237038
- Testing
- laparoscopic Nissen fundoplication short gastric vessel division
- Volunteers
- 87 people
- Sponsor
- Instituto Mexicano del Seguro Social
Obstructive Sleep Apnea, Tonsillar Hypertrophy
Long-term Results of Tonsillectomy in the Treatment of Obstructive Sleep Apnea in Adults
Long-term results of tonsillectomy in the treatment of obstructive sleep apnea in adults
- Conditions
- Obstructive Sleep Apnea, Tonsillar Hypertrophy, Sleep Apnea Syndromes
- Trial name
- NCT05049369
- Testing
- Polysomnography
- Where
- Finland
- Volunteers
- 17 people
- Sponsor
- Turku University Hospital
Glaucoma Open-Angle, Glaucoma Eye
INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register
The study is an observational analysis of patients' medical data recorded in a large-scale register, both retrospective (for patients operated and data recorded before 2018) and prospective (for data collected after 2018) in…
- Conditions
- Glaucoma Open-Angle, Glaucoma Eye, Glaucoma; Drugs, Glaucoma, Angle-Closure
- Trial name
- NCT04381611
- Where
- Switzerland
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Dr. Kaweh Mansouri
Castration-resistant Prostate Cancer
Long-Term Specified Drug Use-Results Survey for Xtandi Capsule
The purpose of this study is to confirm the long term safety and efficacy of enzalutamide in patients.
- Trial name
- NCT02669771
- Testing
- enzalutamide
- Where
- 47 sites in Japan
- Volunteers
- 1,018 people
- Sponsor
- Astellas Pharma Inc
Perineum; Tear, Traumatic, Anal Tear
Perineal Trauma After Jet Ski Accidents and Long-term Functional Outcomes Results
French multicentric retrospective cohort study including patients who underwent an ano-perineal trauma following a personal watercraft/jet-ski accident and that were treated in France from January 2017 to December 2023.
- Conditions
- Perineum; Tear, Traumatic, Anal Tear, Anal Incontinence
- Trial name
- TP-JET (NCT06368284)
- Testing
- Patients who experienced an ano-perineal trauma following a PWC/Jet-Ski accident
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Papillary Thyroid Microcarcinoma, Radiofrequency Ablation
10 Years' Follow-up Results of Ultrasound-guided Radiofrequency Ablation Versus Surgery for Low-risk Papillary Thyroid Micro-carcinoma
Papillary thyroid micro-carcinoma (PTMC) generally demonstrates favorable prognosis. However, the potential risk of disease progression requires careful therapeutic consideration.
- Conditions
- Papillary Thyroid Microcarcinoma, Radiofrequency Ablation, Surgical Resection, Long-term Outcomes
- Trial name
- NCT07107503
- Testing
- Radiofrequency ablation alone, surgical resection
- Volunteers
- 757 people
- Sponsor
- Yi Mao
HIV-1 Infection
Capacity of the Dual Combination Raltegravir/Etravirine to Maintain Virological Success in HIV-1 Infected Patients of at Least 45 Years of Age- ANRS 163 ETRAL
This multicenter, international, non randomized (single arm), open, phase II trial aims to evaluate the capacity of the dual combination raltegravir/etravirine to maintain virological success in virologically suppressed HIV-1…
- Trial name
- NCT02212379
- Testing
- raltegravir and etravirine
- Where
- 19 sites in France, Spain
- Volunteers
- 170 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Stent Thrombosis
Long-Term Safety of Drug Eluting Stents in the "Real World" (FReIburger STent Registry)
The FReIburger STent Registry (FRIST) is designed to determine the long term safety and efficacy of Drug Eluting Stents (DES) in a "real-world" patient population requiring stent implantation.
- Trial name
- FRIST (NCT00905008)
- Testing
- transluminal percutaneous coronary intervention, Drug-Eluting and Bare-Metal stents
- Volunteers
- 1,502 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Coronary Artery Disease, Diabetes Mellitus
Safety and Efficacy of Empagliflozin for Patients With Diabetes Mellitus and Planned Percutaneous Coronary Interventions
Aim: To study the effectiveness and safety of empagliflozin as a preoperative preparation tool, as well as to improve the long-term prognosis of planned percutaneous coronary interventions in patients with type 2 diabetes
- Conditions
- Coronary Artery Disease, Diabetes Mellitus, Percutaneous Coronary Intervention
- Trial name
- SAFARY (NCT04497792)
- Testing
- Empagliflozin 10Mg Tab, hypoglycemic therapy
- Volunteers
- 40 people
- Sponsor
- Research Institute for Complex Problems of Cardiovascular Diseases, Russia
Glaucoma, Glaucoma Patient
Long-Term Clinical Results of Ab-Interno Trabeculotomy in Glaucoma Management
Glaucoma is one of the leading causes of irreversible vision loss worldwide. Elevated intraocular pressure (IOP) is the most important risk factor for the development and progression of the disease.
- Conditions
- Glaucoma, Glaucoma Patient, GLAUCOMA 1, OPEN ANGLE, D (Disorder), Glaucoma Following Surgery
- Trial name
- NCT07780916
- Testing
- Ab-interno trabeculotomy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Wuerzburg University Hospital
Tricuspid Regurgitation
Very Long-term (>15 Years) Results of Tricuspid Valve Repair.
Interest in Tricuspid valve disease grew exponentially in the last years in response to an increased awareness of the poor outcome of patients with functional Tricuspid Regurgitation (TR).
- Trial name
- NCT05836493
- Testing
- Ring annuloplasty, Suture procedure
- Where
- Italy
- Volunteers
- 146 people
- Sponsor
- Michele De Bonis
Liver Tumor
National Polish Registry of Minimally Invasive Liver Surgery
After the two consensus meetings on laparoscopic liver resection in Louisville (2008) and in Morioka (2014) minimally invasive approach for liver resection was finally widely established in liver surgery practice.
- Trial name
- PL-MILS (NCT05516394)
- Testing
- Laparoscopic liver resection
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Medical University of Warsaw
Tibial Fractures
Results of Cross-leg Free Vascularized Fibular Graft
This study aims to evaluate the new technique of cross-leg vascularized fibular graft for reconstruction of post-traumatic long tibial bone defects in terms of restoring normal anatomy and function of the traumatized limb in a…
- Trial name
- NCT06491316
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Assiut University
Dementia, Inappropriate Prescribing
An Intervention to Reduce Inappropriate Medications in Long-term Care Residents With Severe Dementia
An education intervention to promote medication reviews and interdisciplinary discussions within long-term care facilities with the aim of improving medication regimen among residents with severe dementia
- Trial name
- OptimaMed (NCT03539276)
- Testing
- Knowledge exchange
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- CHU de Quebec-Universite Laval
Mixed Hearing Loss
Long Term Results With the Vibrant Soundbridge in Patients With Mixed Hearing Loss: a 60-month Longitudinal Study
Vibrant Soundbridge (VSB, MED-EL, Innsbruck) Active middle ear implants (AMEI) can benefit patients who are unable to use conventional hearing aids (HA) due to medical reasons, discomfort or unsuccessful rehabilitation.
- Trial name
- NCT05793580
- Testing
- Vibrant Soundbridge active middle ear implant
- Where
- France
- Volunteers
- 31 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Plaque-type Psoriasis
Judging the Efficacy of Secukinumab in Patients With Psoriasis Using AutoiNjector: a Clinical Trial Evaluating Treatment Results (JUNCTURE)
The purpose of this study was to demonstrate efficacy of autoinjector administered secukinumab at Week 12 based on PASI and IGA response rates versus placebo in subjects with moderate to severe chronic plaque-type psoriasis.
- Trial name
- JUNCTURE (NCT01636687)
- Testing
- Secukinumab 150mg, Secukinumab 300mg
- Where
- 39 sites in United States, Canada and 3 more
- Volunteers
- 182 people
- Sponsor
- Novartis Pharmaceuticals