Clinical trials: Low Back Pain, active
Low Back Pain
Effects of Motor Control Exercises With and Without Pressure Biofeedback in Recurrent Low Back Pain (MCE)
This study aims to compare the effects of Motor Control Exercises (MCE) with and without Pressure Biofeedback-Guided Training in patients with recurrent low back pain.
- Trial name
- yes (NCT07892079)
- Testing
- Motor Control Exercise with Pressure Biofeedback-Guided Training, Motor Control Exercise
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Management and Technology Lahore
Chronic Non-specific Low Back Pain With Lumbar Multifidus Muscle Injury or Dysfunction
The Intervention Effect of Exercise on Lumbar Multifidus Muscle Injuries
This is a single-center, prospective interventional study. The main purpose is to use ultrasound radiomics to analyze changes in multifidus muscle ultrasound imaging features before and after rehabilitation therapy in patients…
- Trial name
- NCT07892846
- Testing
- Lumbar multifidus muscle rehabilitation exercise
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Chinese PLA General Hospital
Low Back Pain, Low Back Pain and Core Muscle
Gamified Home-Based Core Neuromuscular Training for Chronic Low Back Pain
This randomized controlled trial aims to evaluate the effects of gamified home-based core neuromuscular training on pain intensity, functional disability, core muscular endurance, and exercise adherence in women with chronic…
- Trial name
- NCT07890363
- Testing
- Gamified Intervention Group: core neuromuscular exercise program using a digital application with gamification features, Non-Gamified Control Group
- Volunteers
- 60 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Low Back Pain, Low Back Dysfunction
EFFICACY OF ARTIFICIAL INTELLIGENCE DRIVEN PROGRAM VERSUS TRADITIONAL PHYSICAL THERAPY PROGRAM IN PATIENTS WITH LOW BACK DYSFUNCTION
Low back dysfunction is one of the most common musculoskeletal disorders and is associated with pain, disability, and reduced quality of life.
- Trial name
- AI-LBD (NCT07749833)
- Testing
- AI-Driven Rehabilitation Program, Traditional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Chronic Low Back Pain
Visual Feedback-Assisted Sensorimotor Training in Chronic Nonspecific Low Back Pain
Chronic nonspecific low back pain is a common musculoskeletal condition that can negatively affect physical function and quality of life.
- Trial name
- VF-SMT (NCT07887789)
- Testing
- Visual Feedback-Assisted Sensorimotor Training, Conventional Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Low Back Pain
Therapeutic Exercise and Education for Low Back Pain
This study will evaluate a new treatment program for patients with ongoing or long-term low back pain who receive care at primary care physiotherapy units.
- Trial name
- NCT07713082
- Testing
- Therapeutic Exercise, Education on the self-management of low back pain, Usual Care
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- University of Valladolid
Chronic Pain
Examining Racial and Socioeconomic Differences in Chronic Low Back Pain
The purpose of this research study is to gain a better understanding of how people's racial background and socioeconomic status (e.g., income, education, and employment) impact their experiences of chronic low back pain (cLBP).
- Trial name
- ERASED (NCT05991440)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Washington University School of Medicine
Spine, Low Back Pain
Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain
The goal of this randomized cross-over mechanistic trial is to compare pre- and post-level cortisol and oxytocin changes in patients with chronic spine pain who receive either a hand's on (massage) or a hand's off (talk-based)…
- Conditions
- Spine, Low Back Pain, Neck Pain
- Trial name
- COTHA (NCT06987786)
- Testing
- Massage, Talk-based therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
Chronic Low Back Pain (Non-specific, Uncomplicated)
Comparison of Abdominal Expansion and Abdominal Drawing-In Training With Manual and Verbal Cueing in Chronic Non-Specific Low Back Pain
This study aims to investigate the interactive effects of two core stability training strategies-abdominal drawing-in manoeuvre (ADIM) and Dynamic Neuromusculoskeletal Stabilization abdominal expansion (DNS-AE)-and two…
- Trial name
- NCT07318454
- Testing
- Abdominal Drawing-In Manoeuvre Training, Dynamic Neuromusculoskeletal Stabilization Abdominal Expansion Training
- Volunteers
- 96 people
- Sponsor
- National Yang Ming Chiao Tung University
Acute Low Back Pain (Low Back Pain for Less Than 3 Months)
Preventing the Transition From Acute to Persistent Disabling Low Back Pain Through Cognitive Functional Therapy
Acute low back pain often resolves spontaneously, but some patients develop persistent pain and disability. The goal of this clinical trial is to determine whether Cognitive Functional Therapy (CFT), compared with usual care, can…
- Trial name
- FIN-BACK (NCT07877454)
- Testing
- Cognitive Functional Therapy (CFT), Usual Care
- Where
- Finland
- Volunteers
- 461 people
- Sponsor
- University of Oulu
Lower Back Pain
Electronic Approach to the Human Massage Therapist
The purpose of this study is to gather information about patient experience receiving a massage through a robotic EMMA (Expert Manipulative Massage Automation) compared to receiving a massage from a massage therapist.
- Trial name
- NCT07040397
- Testing
- EMMA massage therapy, Clinical massage treatment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Degenerative Disc Disease
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease
This is a Phase III, randomized, double-blinded, Sham-controlled, multi-center study in subjects with single-level, symptomatic lumbar (L3- S1) intervertebral disc degeneration.
- Trial name
- IDCT (NCT07254806)
- Testing
- IDCT (rebonuputemcel)
- Where
- 31 sites in United States
- Volunteers
- 162 people
- Sponsor
- DiscGenics, Inc.
Low Back Pain, Chronic Low Back Pain
Pain Neuroscience Education and Neuromuscular Exercise in Individuals With Chronic Low Back Pain and Central Sensitization
The goal of this randomized controlled study is to evaluate the effectiveness of pain neuroscience education (PNE) combined with neuromuscular exercises (NME) in individuals with chronic low back pain and central sensitization…
- Conditions
- Low Back Pain, Chronic Low Back Pain, Central Sensitization
- Trial name
- NCT07866690
- Testing
- Pain Neuroscience Education, Neuromuscular Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Izmir Katip Celebi University
Chronic Nonspecific Low-back Pain, CNSLBP
Effects of Virtual Reality Exergames Versus Spinal Manipulation in Chronic Nonspecific Low Back Pain
The goal of this clinical trial is to compare the acute effects of virtual reality exergames (VR-EXG) and spinal manipulation on pain, kinesiophobia, mood states, functional disability and lumbar range of motion in individuals…
- Trial name
- NCT07876960
- Testing
- Virtual Reality, Spinal manipulation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Chronic Low Back Pain (Non-specific, Uncomplicated)
Immediate Effects of Manual and Verbal Cueing During Movement Control Training in Chronic Non-Specific Low Back Pain
Chronic non-specific low back pain is commonly associated with impaired movement control. Movement control training is often used in rehabilitation, and different cueing methods may influence how patients perform and learn…
- Trial name
- NCT07324538
- Testing
- Movement Control Training With Manual Cueing, Movement Control Training With Verbal Cueing
- Where
- 2 sites in Taiwan
- Volunteers
- 40 people
- Sponsor
- National Yang Ming Chiao Tung University
Low Back Pain
Feasibility of Identifying Brain Mechanisms of Qigong and Behavioral Outcomes After Qigong Practice in People With Chronic Low Back Pain
The long-term objective of this investigation is to identify how Qigong affects brain function in brain areas relevant to patients with chronic low back pain (cLBP), thereby setting a foundation from which to perform further…
- Trial name
- NCT04164225
- Testing
- Qigong Exercise, P.Volve Exercises
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
Chronic Pain, Intractable Pain
Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control
Study to evaluate the effectiveness of time variant pulse (TVP)-SCS in patients with chronic pain using commercially approved Boston Scientific SCS Systems per local Instructions for use (IFU).
- Conditions
- Chronic Pain, Intractable Pain, Low Back Pain, Chronic Low-back Pain
- Trial name
- MOSAIC (NCT07190807)
- Testing
- Boston Scientific WaveWriter Alpha™ SCS Systems
- Where
- 7 sites in United States
- Volunteers
- 70 people
- Sponsor
- Boston Scientific Corporation
Non-specific Low Back Pain
Comparing Myofascial Exercise and Trigger Point Therapy for Non-Specific Low Back Pain
The goal of this clinical trial is to learn if two common physical therapy approaches, used alone or together, can help reduce pain and improve daily function in adults with nonspecific low back pain.
- Trial name
- NCT07362420
- Testing
- Myofascial Trigger Point Manual Compression, Myofascial Chain-Based Specific Exercise
- Where
- 2 sites in Taiwan
- Volunteers
- 105 people
- Sponsor
- National Yang Ming Chiao Tung University
Chronic Low Back Pain, Spinal Cord Injury
SERENITY Study of Chronic Pain Interference in Adults
SERENITY is a remote observational study designed to characterize inter-individual differences in chronic pain among adults with chronic low back pain and adults with spinal cord injury-related neuropathic pain.
- Conditions
- Chronic Low Back Pain, Spinal Cord Injury, Neuropathic Pain, Chronic Pain
- Trial name
- SERENITY (NCT07820475)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Minnesota