Clinical trials: Low Back Pain (LBP)
Patients With Chronic Mechanical LBP
Core Stability Exercise Versus Aerobic Exercise on Pain, Range of Motion and Function in Patients With Chronic Mechanical Low Back Pain: Randomized Controlled Trial
Chronic mechanical low back pain (CMLBP) is a prevalent musculoskeletal condition characterized by persistent pain originating from the spine, muscles, ligaments, or intervertebral discs.
- Trial name
- NCT06634511
- Testing
- core stability exercises
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- Cairo University
Chronic Low Back Pain, Gait
Complexity & Distraction in LBP
Motor control, notably expressed through the complexity of the variability of the locomotor pattern, is disturbed at the central level by an apprehension of pain and movement, more than pain itself (or by biomechanical /…
- Conditions
- Chronic Low Back Pain, Gait, Motor Activity
- Trial name
- CoDiLoBP (NCT03633578)
- Testing
- walk test
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Low Back Pain, Quality of Life
Low Back Pain and Quality of Life Among the Ambulance Drivers in Malaysia's Hospitals
The study is a community interventional study by using an integrated back pain module (IBPM). The purpose of this study is to find out if the module training has any benefit on Low Back pain among ambulance drivers.
- Trial name
- NCT04824846
- Testing
- Integrated back pain module (IBPM), Health Educational Pamphlet.
- Where
- Malaysia
- Volunteers
- 198 people
- Sponsor
- Universiti Sains Malaysia
Low Back Pain, Low Back Pain, Mechanical
Diaphragm Function in Low Back Pain People
Pathomechanism of nonspecific low back pain is not clear for the researchers yet. Our aim is to evaluate the function of one of the stabilizer muscles of the low back area. Diaphragm's postural function is evident.
- Trial name
- LBP_DIA (NCT05486858)
- Testing
- MSK ultrasonograpy, sitting Functional and Lateral Reach Test
- Where
- Hungary
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Szeged University
Pain, Back
Implementation of the ACP Guideline for Low Back Pain (IMPACt-LBP)
The purpose of this study is to assess whether the primary spine practitioner (PSP) model of care will lead to improvements in patient outcomes, as compared to usual care, based on change in patient-reported PROMIS Pain…
- Trial name
- IMPACt-LBP (NCT05626049)
- Testing
- Primary Spine Provider Model, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 1,800 people
- Sponsor
- Duke University
Central Sensitization, Low Back Pain
Verbalization in Patients With Non-specific Low Back Pain and Central Sensitization
The primary goal of this study is to examine the effects of limiting complaints on pain and pain catastrophizing (PC) in individuals with low back pain (LBP) who are in a state of central sensitization (CS).
- Conditions
- Central Sensitization, Low Back Pain, Pain Catastrophizing
- Trial name
- NCT01705600
- Testing
- Pain Verbalization Repression Rules
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Keystone Rehabilitation Systems
Low Back Pain
Special Lower Back Pillow Examination
Low back pain is a significant, serious and widespread problem in our world today, both in terms of social and economic burdens.
- Trial name
- LBP PILLOW (NCT05486845)
- Testing
- survey
- Where
- Hungary
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Szeged University
Moderate to Severe Acute Lower Back Pain
Safety and Efficacy of SP-103 in Subjects With Moderate to Severe Acute Lower Back Pain
This is a Phase 2, randomized, double-blind, placebo-controlled, parallel group, multicenter study to evaluate the safety and efficacy of SP-103 in subjects with moderate to severe acute lower back pain.
- Trial name
- NCT05096494
- Testing
- SP-103
- Where
- 10 sites in United States
- Volunteers
- 76 people
- Sponsor
- Scilex Pharmaceuticals, Inc.
Intervertebral Disc Degeneration, Chronic Low-back Pain
Efficacy of Intradiscal Injection of Autologous BM-MSC in Subjects With Chronic LBP Due to Multilevel Lumbar IDD
DREAM is a phase II B efficacy monocentric, prospective, randomized, controlled double blinded trial, comparing intra-discal autologous adult bone marrow mesenchymal stem cells (BM-MSC) therapy and sham treated controls in…
- Trial name
- DREAM (NCT05066334)
- Testing
- Autologous BM-MSC
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Chronic Low Back Pain (CLBP)
Impairment Based Treatment Versus Modified Functional Restoration Program in Chronic Low Back Pain Patients
The aim of this feasibility study is to evaluate the practicality of conducting a future randomized controlled trial comparing two rehabilitation approaches for older adults with degenerative chronic low back pain…
- Trial name
- FIRM-CLBP (NCT07699419)
- Testing
- Impairment-based trearment, Modified Functional restoration program
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Low Back Pain, Pain, Chronic
What Determines a Positive Outcome of Spinal Manipulation for Persistent Low Back Pain: Stiffness or Pain Sensitivity? A Randomized Trial
Introduction Several treatment methods have been proposed to ease the burden of low back pain (LBP) but none are clearly superior.
- Trial name
- POPS (NCT04086667)
- Testing
- Spinal manipulation
- Where
- Denmark
- Volunteers
- 132 people
- Sponsor
- Spine Centre of Southern Denmark
Chronic Low Back Pain
The Impact of Epidural Steroid Analgesia on Functional MRI for Patients With LBP
Chronic low back pain (CLBP) is the most prevalent form of chronic pain, and the most common reason for disability in working-age population [2].
- Trial name
- NCT01913782
- Where
- Taiwan
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Chronic Low Back Pain, Neuropathic Pain
Sham-Controlled RCT on 10kHz High-Frequency Spinal Cord Stimulation for Chronic Neuropathic Low Back Pain (Modulate-LBP)
Multicentre, randomised, double-blinded, sham-controlled trial with parallel economic evaluation. Patients will be allocated 1:1 to activated 10kHz SCS plus usual care (intervention) or sham 10kHz SCS plus usual care (control)…
- Conditions
- Chronic Low Back Pain, Neuropathic Pain, Refractory Pain
- Trial name
- Modulate-LBP (NCT03470766)
- Testing
- Nevro Senza System (HF10 Therapy)
- Where
- 2 sites in United Kingdom
- Volunteers
- 41 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Conditions
Association Between TMD and LBP Back Pain
Investigate the relationships between temporomandibular disorder and low back pain
- Trial name
- NCT03139175
- Testing
- balance assessment with Biodex balance system
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Low Back Pain, Paraspinal Muscle
Sodium Aescinate for the Treatment of Low Back Pain (LBP) in Adults
The goal of this clinical trial is to assess the clinical efficacy and safety of sodium aescinate in treating low back pain (LBP) in adult participants.
- Conditions
- Low Back Pain, Paraspinal Muscle, CLBP - Chronic Low Back Pain, Non-specific Chronic Low Back Pain
- Trial name
- NCT07339631
- Testing
- Sodium Aescinate Tablets
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xijing Hospital
Low Back Pain
Dose of Spinal Manipulation for Chronic Low Back Pain
This study will determine the number of visits to a chiropractor for spinal manipulation, light massage, and ultrasound necessary for optimal relief of chronic low back pain.
- Trial name
- NCT00376350
- Testing
- Spinal Manipulation, Light Massage, Pulsed Ultrasound
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Western States
Low Back Pain, Spondylolisthesis
Effects of Exercise Intervention in Patients With Spondylolisthesis Related LBP
The first purpose of this study is to define parameters of the trunk neuromuscular functions that are pathologically altered in patients with low back pain due to spondylolytic spondylolisthesis.
- Trial name
- EXER-SPO-TNC (NCT01985776)
- Testing
- Exercise intervention, Exercise and e-stim
- Where
- 4 sites in Slovenia
- Volunteers
- 48 people
- Sponsor
- University of Primorska
Low Back Pain, Orthopedic Disorder
Evaluation on the Effects of Two Rehabilitation Treatment and Tape for Functional and Motor Recovery of LBP Patients
The objective of this study is to verify which is the most effective type of rehabilitation treatment (rehabilitation based on core strengthening vs pilates) in patients suffering from low back pain.
- Conditions
- Low Back Pain, Orthopedic Disorder, Physical Therapy, Core Strengthening
- Trial name
- LBPT001 (NCT05419310)
- Testing
- Rehabilitation - core strengthening, Rehabilitation - rehabilitation pilates, Elastic taping application
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Campus Bio-Medico University
Low Back Pain, Guideline Adherence
Understanding How Physiotherapists in Türkiye Follow Low Back Pain Guidelines and What Affects Their Use of Research in Practice
The goal of this observational study is to understand how physiotherapists and physiotherapy students in Türkiye manage low back pain and how closely they follow clinical practice guidelines and use research evidence.
- Conditions
- Low Back Pain, Guideline Adherence, Physiotherapist, Physiotherapist Students
- Trial name
- NCT07178548
- Testing
- Online Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Medipol University
Derangement; Low Back
Cyriax Manipulation in Lumbar Derangement Syndrome
the objective of the study was to determine the effect of Cyriax manipulation for Pain, range of motion and quality of life in lumbar internal derangement radiculopathy in single physical therapy session.
- Trial name
- NCT04082065
- Testing
- conventional physical therapy, cyriax lumber manipulation group
- Where
- Pakistan
- Volunteers
- 43 people
- Sponsor
- Riphah International University